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PALMATINE

  • Palmatine
  • Chemical compound

    Palmatine is a protoberberine alkaloid found in several plants including Coptis chinensis (Rhizoma coptidis, chinese goldthread), Corydalis yanhusuo,

    Palmatine

    Palmatine

    Palmatine

  • Corydalis yanhusuo
  • Species of flowering plant in the poppy family

    alkaloid. Corydalis yanhusuo also contains the alkaloids glaucine and palmatine. It also contains the acetylcholinesterase inhibitor corydaline.

    Corydalis yanhusuo

    Corydalis_yanhusuo

  • Corydaline synthase
  • Enzyme

    chemical reaction palmatine + SAM + 2 NADPH     H+         corydaline + SAH + 2 NADP+   This is a methylation reaction in which palmatine is converted to

    Corydaline synthase

    Corydaline synthase

    Corydaline_synthase

  • Berberis vulgaris
  • Species of shrub

    alkaloids; the primary constituents include berberine, oxyacanthine, palmatine, berberrubine, lambertine, obamegine, aromoline, columbamine, berlambine

    Berberis vulgaris

    Berberis vulgaris

    Berberis_vulgaris

  • Phellodendron amurense
  • Species of tree

    major chemical constituents of its bark are the isoquinoline alkaloids, palmatine, jatrorrhizine, phellodendorine with berberine found within the leaves

    Phellodendron amurense

    Phellodendron amurense

    Phellodendron_amurense

  • Coptis chinensis
  • Species of flowering plant

    rhizomes of Coptis chinensis contain the isoquinoline alkaloids berberine, palmatine, and coptisine among others. Coptis chinensis is one of the 50 fundamental

    Coptis chinensis

    Coptis_chinensis

  • SkQ
  • Class of organic molecules

    properties. The cations with the well-known medical properties — berberine and palmatine were also tested. SkQBerb and SkQPalm – SkQ derivatives, do not differ

    SkQ

    SkQ

  • Columbamine O-methyltransferase
  • Enzyme

              palmatine + SAH   This is a methylation reaction in which the benzylisoquinoline alkaloid, columbamine, is converted to palmatine. The methyl

    Columbamine O-methyltransferase

    Columbamine O-methyltransferase

    Columbamine_O-methyltransferase

  • Corydaline
  • Chemical compound

    platelet aggregation in vitro (IC50 = 54.16 μg/ml). In Corydalis cava, palmatine is converted to corydaline by the enzyme corydaline synthase. The methyl

    Corydaline

    Corydaline

    Corydaline

  • Nephroia carolina
  • Species of flowering plant

    lactone, loliolide; and three alkaloids, sinoacutine, magnoflorine, and palmatine. The common name for this plant in East Texas is Margil's Vine, referencing

    Nephroia carolina

    Nephroia carolina

    Nephroia_carolina

  • Tetrahydropalmatine
  • Isoquinoline alkaloid, found mainly in Corydalis

    tetrahydroberberine oxidase, which oxidises it to palmatine: tetrahydropalmatine + H+     2 O2 2 H2O2       palmatine L-THP has a pharmacokinetic profile that

    Tetrahydropalmatine

    Tetrahydropalmatine

    Tetrahydropalmatine

  • HEC96719
  • Chemical compound

    Hongwei; Song, Danqing (January 2023). "Discovery and development of palmatine analogues as anti-NASH agents by activating farnesoid X receptor (FXR)"

    HEC96719

    HEC96719

    HEC96719

  • Phellodendrine
  • Chemical compound

    originally from Phellodendron amurense (Rutaceae). Berberine Jatrorrhizine Palmatine SHIMAMOTO K, JUJIHARA M, TORII H (March 1962). "[Pharmacological studies

    Phellodendrine

    Phellodendrine

    Phellodendrine

  • Huang Bai
  • Herb in Chinese medicine

    12alpha-hydroxylimonin nomilin γ-Fagarine canthin-6-one 4-methoxy-N-methyl-2-quinolone palmatine and oxypalmatine (+/-)-lyoniresinol β-sitosterol stigmasterine amurenlactone

    Huang Bai

    Huang Bai

    Huang_Bai

  • Columbamine
  • Organic chemical

    methylation reaction catalysed by columbamine O-methyltransferase produces palmatine. The methyl group comes from the cofactor, S-adenosyl methionine (SAM)

    Columbamine

    Columbamine

    Columbamine

  • Zanthoxylum coco
  • Species of tree

    α-fagarine, fagarine-2, magnoflorine, nitidine, chelerythrine, berberine, palmatine and candicine have been isolated from the foliage and wood. The coco belongs

    Zanthoxylum coco

    Zanthoxylum coco

    Zanthoxylum_coco

  • Anamirta cocculus
  • Climbing plant

    The stem and the roots contain quaternary alkaloids, such as berberine, palmatine, magnoflorine and columbamine. The seeds deliver picrotoxin, a sesquiterpene

    Anamirta cocculus

    Anamirta cocculus

    Anamirta_cocculus

  • Jatrorrhizine
  • Chemical compound

    DE (1988). "Natural protoberberine alkaloids from Enantia chlorantha, palmatine, columbamine and jatrorrhizine for thioacetamide-traumatized rat liver"

    Jatrorrhizine

    Jatrorrhizine

    Jatrorrhizine

  • Coscinium fenestratum
  • Species of flowering plant

    bioactive ingredient in Coscinium fenestratum is berberine, but also palmatine and jatrorrhizine. Because of the growing populations and industrialization

    Coscinium fenestratum

    Coscinium fenestratum

    Coscinium_fenestratum

  • Phellodendron
  • Genus of trees

    Phellodendrine has promise as an immune suppressant[citation needed] Palmatine may be a vasodilator[citation needed] The phytochemical descriptions are

    Phellodendron

    Phellodendron

    Phellodendron

  • Canadine
  • Chemical compound

    the phthalideisoquinoline structural subgroup. (S)-Canadine, berberine, palmatine, and hydrastine are the major alkaloids present in goldenseal. In Corydalis

    Canadine

    Canadine

    Canadine

  • Berberis koreana
  • Species of shrub

    as berberine, canadine, columbamine, corypalmine, jatrorrhizine, and palmatine. These alkaloids are all very similar in chemical structure, but they

    Berberis koreana

    Berberis koreana

    Berberis_koreana

  • Tetrahydroberberine oxidase
  • Type of enzyme

    (S)-isocorypalmine is oxidised to columbamine; tetrahydropalmatine to palmatine, and tetrahydropapaverine to papaverine. (S)-isocorypalmine + H+     2

    Tetrahydroberberine oxidase

    Tetrahydroberberine oxidase

    Tetrahydroberberine_oxidase

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