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Protein-coding gene in the species Homo sapiens
cohesion protein PDS5 homolog A is a protein that in humans is encoded by the PDS5A gene. GRCh38: Ensembl release 89: ENSG00000121892 – Ensembl, May 2017 GRCm38:
PDS5A
Protein complex that regulates the separation of sister chromatids during cell division
motifs for separase cleavage and a region that is competitively bound by PDS5A, PDS5B or NIPBL. The C-terminal domain of RAD21 forms a winged helix that
Cohesin
Protein-coding gene in the species Homo sapiens
single strand or a pair of sister chromosomes. WAPL forms a complex with PDS5A or PDS5B and releases cohesin from DNA by opening the interface between
Wings apart-like protein homolog
Wings_apart-like_protein_homolog
Mechanism of nuclear organization
"The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism". Nature Structural & Molecular Biology. 29 (6): 586–591
Loop_extrusion
for the establishment of cohesion. In humans, the gene has two homologs, Pds5A and Pds5B. Pds5 interacts with chromatin-associated cohesin. Pds5 is not
Establishment of sister chromatid cohesion
Establishment_of_sister_chromatid_cohesion
Q86YL7 11914 PDPR HGNC:30264; Q8NCN5 11915 PDRG1 HGNC:16119; Q9NUG6 11916 PDS5A HGNC:29088; Q29RF7 11917 PDS5B HGNC:20418; Q9NTI5 11918 PDSS1 HGNC:17759;
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Protein-coding gene in humans
and calpain to cleave, as well as a region that is competitively bound by PDS5A, PDS5B or NIPBL. The C-terminal domain of RAD21 forms a winged helix that
RAD21
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PDS5A
PDS5A
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