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American Baptist minister (1930–2005)
Estus Washington Pirkle (March 12, 1930 – March 3, 2005) was an American Baptist minister, evangelist, and filmmaker. Estus Washington Pirkle was born in Vienna
Estus_Pirkle
Surname list
Pirkle is a surname. Notable people with the surname include: Clay Pirkle (born 1967), American politician Estus Pirkle (1930–2005), American Baptist
Pirkle
American photographer
Pirkle Jones (January 2, 1914 – March 15, 2009) was an American documentary photographer and educator. Pirkle Jones was born in Shreveport, Louisiana
Pirkle_Jones
American television sitcom (2015–2019)
Airborne Division. Dianne Wiest as Dr. Joan (Pirkle) Short: Wife of John Short; therapist; daughter of GiGi Pirkle; mother of Heather (Short) Hughes, Matt
Life_in_Pieces
Chemical compound
Pirkle's alcohol is an off-white, crystalline solid that is stable at room temperature when protected from light and oxygen. This chiral molecule is typically
Pirkle's_alcohol
United States historic place
The Bowman-Pirkle House is a historic two-story log house in Buford, Georgia. It was built in 1818 for John Bowman, who served under General Andrew Jackson
Bowman-Pirkle_House
American politician
Clay Pirkle is an American politician. He was a Republican member of Georgia House of Representatives from District 169, representing Ben Hill, Irwin,
Clay_Pirkle
American horror film
Galeen Dracula by Bram Stoker (uncredited) Produced by Derek Zemrak Leonard Pirkle Paula Elins Jenna Cedicci Emrhys Cooper Don Barton Starring Doug Jones Sarah
Nosferatu_(2023_film)
1971 American film
featuring Southern Baptist minister Estus Pirkle. The film is based on and shares its name with a sermon by Estus W. Pirkle held on January 31, 1968 at Camp Zion
If Footmen Tire You, What Will Horses Do?
If_Footmen_Tire_You,_What_Will_Horses_Do?
Georgia racecar museum
founded in 2002 by local businessman Gordon Pirkle. Exhibits and artifacts for the museum were collected by Pirkle or donated by racers and collectors within
Georgia_Racing_Hall_of_Fame
Species of plant
Mathews, Thomas P.; Harden, Leslie A.; Takeoka, Gary R.; Thomas, Jerry D.; Pirkle, James L.; Johnson, Rudolph C. (13 July 2016). "Quantification of toxins
Ackee
American photojournalist (1895–1965)
magazine Aperture. In the mid-1950s, Life magazine commissioned Lange and Pirkle Jones to shoot a documentary about the death of the town of Monticello,
Dorothea_Lange
American photographer and environmentalist (1902–1984)
became accomplished photographers in their own right. His assistants were: Pirkle Jones (1914–2009), assisting from 1947–1953 Don Worth (1924–2009), assisting
Ansel_Adams
State district in Georgia, USA
Turner County, as well as parts of Coffee County and Tift County. Clay Pirkle (2023–2025) Angie O'Steen (since 2025) https://statisticalatlas
Georgia's 169th House of Representatives district
Georgia's_169th_House_of_Representatives_district
Chemical separation technique
complexes. Most of the types of stationary phases can be classified as Pirkle type (Brush type), Protein-based, Cyclodextrins based, Polymer-based carbohydrates
Chiral_column_chromatography
Species of plant
Mathews, Thomas P.; Harden, Leslie A.; Takeoka, Gary R.; Thomas, Jerry D.; Pirkle, James L.; Johnson, Rudolph C. (October 2018). "Quantitative HPLC–MS/MS
Melicoccus_bijugatus
County in Georgia, United States
black men in connection with the assault, including Tony Howell and Isaiah Pirkle. That same afternoon members of numerous area black churches gathered for
Forsyth_County,_Georgia
City in Georgia, United States
leaving some information unavailable or unverifiable. W. W. Pirkle (possible) T. J. Pirkle (possible) E. F. Smith (possible) Charles Leon Harris, term
Cumming,_Georgia
Illinois, United States, in 1952, originally as "Pirkle Lee and the Five Stars". It comprised Pirkle Lee Moses Jr. (lead vocals), Louis Bradley and Arthur
The_El_Dorados
American filmmaker and showman (1910–1981)
Christianity and began making Christian films. He collaborated with Estus Pirkle on If Footmen Tire You, What Will Horses Do? (1971), The Burning Hell (1974)
Ron_Ormond
American politician
January 12, 2015 – January 9, 2023 Preceded by Chuck Sims Succeeded by Clay Pirkle Personal details Born (1971-05-23) May 23, 1971 (age 55) Douglas, Georgia
Dominic_LaRiccia
Jodi Lott retired. District 135: David Knight retired. District 169: Clay Pirkle retired. District 170: Penny Houston retired. District 42: Doug Stoner retired
2024 Georgia House of Representatives election
2024_Georgia_House_of_Representatives_election
2008 ROM hack of EarthBound
defeating Giygas. Varik, the main character, is hired by ex-mayor B. H. Pirkle to investigate a murder, and is given a key to the sewers to find clues
EarthBound_Halloween_Hack
Aspect of Christian media
If Footmen Tire You, What Will Horses Do? was based on a sermon by Estus Pirkle held on January 31, 1968, at Camp Zion in Myrtle Mississippi with the title
Christian_film_industry
Dam in Napa County, California
had to be relocated to higher ground. Photographers Dorothea Lange and Pirkle Jones documented the town and its people before the town was flooded by
Monticello_Dam
Liquid fuel derived from petroleum
Exposure on Crime" (PDF). National Bureau of Economic Research. "a" ref citing Pirkle, Brody, et al. (1994). Archived (PDF) from the original on 17 January 2024
Gasoline
Pennsylvania Supreme Court denied the board's petition for appeal. See also Pirkle v. Wolf. "Supreme Court tosses out another Republican 2020 election challenge"
Post-election lawsuits related to the 2020 U.S. presidential election from Pennsylvania
Post-election_lawsuits_related_to_the_2020_U.S._presidential_election_from_Pennsylvania
Scientific publications term
including polysaccharides, cyclodextrins, glycopeptide antibiotics, proteins, Pirkle, crown ethers, etc. to achieve analysis of chiral molecules. This term has
Chiral_analysis
1987 studio album by Negativland
"Christianity Is Stupid", a track featuring samples of evangelist Estus Pirkle from his film If Footmen Tire You, What Will Horses Do?, proved to be an
Escape_from_Noise
Reservoir in California, United States
This abandonment was chronicled by the photographers Dorothea Lange and Pirkle Jones in their work Death of a Valley, published in Aperture magazine in
Lake_Berryessa
1987 film by Paul Verhoeven
John Landis appears in an in-film advertisement. Smith's partner, Joan Pirkle, appears as Dick Jones's secretary. RoboCop was conceived in the early 1980s
RoboCop
2002 video game
AWE Games Publisher THQ Designer Scott Nixon Composers Joe Abbati Will Pirkle Series SpongeBob SquarePants Platform Microsoft Windows Release NA: September
SpongeBob SquarePants: Employee of the Month
SpongeBob_SquarePants:_Employee_of_the_Month
CH3OH; simplest possible alcohol
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Methanol
1998 space western anime television series
to begin with—or have seen any other anime series prior." Michelle Onley Pirkle, in her book Science Fiction Film, Television, and Adaptation: Across the
Cowboy_Bebop
City in Georgia, United States
Branch on his way to the First Seminole War in 1818. The historic Bowman-Pirkle House, built that same year, was originally located on the border of Flowery
Flowery_Branch,_Georgia
Electronic musical instrument
September 2005). "Moog Filter Module in VHDL 2005". Sound of L.A. Music. Will Pirkle (2013). "Virtual Analog Filter Implementation and Comparisons" (PDF). www
Moog_synthesizer
Simplest secondary alcohol
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Isopropyl_alcohol
Organic compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Ethanol
1987 American film
assortment of clips from classic movies and archival footage. Don King Estus Pirkle Michael Agbabian James Allport Lazaro Arvizubr Stephen Augustine Tracy Bauer
Heaven_(1987_film)
Petrea, state representative from the 166th District (2015–present) Clay Pirkle, state representative from the 155th District (2015–present) Robert Pruitt
2022 Georgia gubernatorial election
2022_Georgia_gubernatorial_election
Stages in the development of children
from the original (PDF) on 2017-06-17. Retrieved 2012-12-06. Brody DJ, Pirkle JL, Kramer RA, Flegal KM, Matte TD, Gunter EW, Paschal DC (July 1994). "Blood
Child_development
Organolead compound
Economic Research. Archived 13 July 2024 at the Wayback Machine "a" ref citing Pirkle, Brody, et. al (1994). Retrieved 17 August 2009. "Blood Lead Reference Value"
Tetraethyllead
State district in Georgia, USA
Representatives. It contains the entirety of Johnson County and Laurens County. Clay Pirkle (2015–2023) Matt Hatchett (since 2023) https://statisticalatlas
Georgia's 155th House of Representatives district
Georgia's_155th_House_of_Representatives_district
High-capacity electrochemical capacitor
Shanthi; Stoller, Meryl D.; Ganesh, K. J.; Cai, Weiwei; Ferreira, Paulo J.; Pirkle, Adam; Wallace, Robert M.; Cychosz, Katie A.; Thommes, Matthias; Su, Dong;
Supercapacitor
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Trifluoromethanol
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Mannitol
Chemical reaction which exchanges the R groups of an alcohol and ester
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Transesterification
John Humble (MFA 1973), photographer of the Los Angeles urban landscape Pirkle Jones (class of 1946), documentary photographer, educator Annie Leibovitz
List of San Francisco Art Institute people
List_of_San_Francisco_Art_Institute_people
Repertory Theatre was founded as Tennessee Repertory Theatre in 1985 by Mac Pirkle and Martha Rivers Ingram. The first production was Macbeth. The theatre's
Nashville_Repertory_Theatre
Sugar alcohol that is used as a sweetener
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Erythritol
Aromatic alcohol
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Benzyl_alcohol
Miocene geologic formation in Florida
Bulletin of the Florida State Museum, Biological Sciences. 7 (2): 53–97. Pirkle, E. C. (December 1956). "The Hawthorne and Alachua Formations of Alachua
Alachua_Formation
Mammalian protein found in humans
277 (12): 9989–9996. doi:10.1074/jbc.M111399200. PMID 11788601. Crider-Pirkle S, Billingsley P, Faust C, Hardy DM, Lee V, Weitlauf H (May 2002). "Cubilin
Cubilin
Biannual Royal Society of Chemistry award
Taitiro Fujinaga 1996 (1996): James D. Winefordner 1998 (1998): William H. Pirkle 2000 (2000): William Horwitz 2002 (2002): Michael Thompson 2004 (2004):
Robert Boyle Prize for Analytical Science
Robert_Boyle_Prize_for_Analytical_Science
Method for preparing ethers
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Williamson_ether_synthesis
Mathews, Thomas P.; Harden, Leslie A.; Takeoka, Gary R.; Thomas, Jerry D.; Pirkle, James L.; Johnson, Rudolph C. (13 July 2016). "Quantification of toxins
List_of_poisonous_plants
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Isoamyl_alcohol
Smoke directly released into the air from a burning cigarette, cigar, or smoking pipe
doi:10.1007/s11065-007-9035-9. PMID 17690985. S2CID 25382242. Bernert JT, Pirkle JL, Xia Y, Jain RB, Ashley DL, Sampson EJ (November 2010). "Urine concentrations
Sidestream_smoke
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
1-Octanol
Census-designated place in California, United States
Church and Japanese School building. In 1961, documentary photographer Pirkle Jones did a photo essay on Walnut Grove. The Walnut Grove Buddhist Church
Walnut_Grove,_California
City in Mississippi, United States
Paquin, poet Steve Patterson, politician John Pennebaker, politician Estus Pirkle, Baptist minister and filmmaker Matthew Prater, musician Mike Ratliff, basketball
New_Albany,_Mississippi
Racially motivated violence and subsequent racial cleansing in Forysth County in 1912
suspect, along with alleged accomplices Johnny Bates, Fate Chester, Isaiah Pirkle, and Joe Rogers. The five black men were placed in the small Forsyth County
1912 racial conflict in Forsyth County, Georgia
1912_racial_conflict_in_Forsyth_County,_Georgia
Chemical compound (CH3)2CHCH2OH
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Isobutanol
Active ingredient in fermented drinks
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Alcohol_(drug)
U.S. House district for Mississippi
Kelly 14,418 16.32 Nonpartisan Mike Tagert 11,231 12.71 Nonpartisan Greg Pirkle 7,142 8.08 Nonpartisan Starner Jones 6,993 7.91 Nonpartisan Chip Mills 6
Mississippi's 1st congressional district
Mississippi's_1st_congressional_district
Chemical compound family
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Amyl_alcohol
Primary alcohol compound (CH3CH2CH2OH)
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
1-Propanol
Primary alcohol with formula C26H54O
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
1-Hexacosanol
Natural sweetener
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Xylitol
Land grant in California
promoted the dam. Residents started leaving the valley. Dorothea Lange and Pirkle Jones were commissioned to shoot a photographic documentary of the death
Rancho_Las_Putas
Organic compound with at least one hydroxyl (–OH) group
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Alcohol_(chemistry)
Poisoning caused by lead in the body
Retrieved 2023-01-15. Jones RL, Homa DM, Meyer PA, Brody DJ, Caldwell KL, Pirkle JL, Brown MJ (March 2009). "Trends in blood lead levels and blood lead testing
Lead_poisoning
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Cetyl_alcohol
Radio station in Maryville, Tennessee, United States
until November 1. On November 1, ownership of WNFZ was returned to John W. Pirkle and that station switched to News/Talk. It was announced on May 28, 2014
WDKW
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Phenethyl_alcohol
Former art school in San Francisco, California
typographers to design fonts for computers. Alumni Ruth-Marion Baruch and Pirkle Jones documented the early days of the Black Panther Party in northern California
San_Francisco_Art_Institute
Cruz; Joseph Keaweʻaimoku Kaholokula; Chantelle Eseta Matagi; Catherine M. Pirkle; Emily K. Roberson; Tetine Sentell; Lisa Watkins-Victorino; Courtni A. Andrews;
Demographics of Filipino Americans
Demographics_of_Filipino_Americans
Chemical compound (C4H9OH)
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
1-Butanol
American actor (born 1943)
Stanford University (MFA) Occupation Actor Years active 1970–present Spouses Cecilia Souza (m. 1964; div. 1974) Joan Pirkle (m. 1988) Children 2
Kurtwood_Smith
American materials scientist
Murali, Meryl D Stoller, KJ Ganesh, Weiwei Cai, Paulo J Ferreira, Adam Pirkle, Robert M Wallace, Katie A Cychosz, Matthias Thommes, Dong Su, Eric A Stach
Eric_Stach
District Attorney Chip Mills, Itawamba County Prosecutor Greg Pirkle, attorney and son of Estus Pirkle Henry Ross, former mayor of Eupora and candidate for the
2015 Mississippi's 1st congressional district special election
2015_Mississippi's_1st_congressional_district_special_election
American photographer (1922–1997)
War II. Baruch's works, in collaboration with photographer and husband Pirkle Jones, including Illusion For Sale, and a series on the Black Panther Party
Ruth-Marion_Baruch
Organic compound ethane-1,2-diol
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Ethylene_glycol
Ion, and compounds containing the ion
from the original (PDF) on October 13, 2006. Benjamin C. Blount; James L. Pirkle; John D. Osterloh; Liza Valentin-Blasini & Kathleen L. Caldwell (2006).
Perchlorate
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
1-Heptacosanol
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
2-Ethylhexanol
Chemical compound
cognition and memory disorder drugs Thiazide diuretics Uzunov DP, Zivkovich I, Pirkle WH, Costa E, Guidotti A (August 1995). "Enantiomeric resolution with a new
IDRA-21
American street artist and activist (born 1970)
documented that Fairey has appropriated work by Koloman Moser, Ralph Chaplin, Pirkle Jones, Rupert Garcia, Rene Mederos, Félix Beltrán, and Gary Grimshaw, among
Shepard_Fairey
1989 song by Negativland
KPIX-TV's coverage of the Brom hoax, the piece also includes samples from Estus Pirkle, Charles Manson, and the Beatles song "Helter Skelter". Robert Christgau
Helter_Stupid_(song)
Inhalation of tobacco smoke by persons other than the intended active smoker
doi:10.1007/s11065-007-9035-9. PMID 17690985. S2CID 25382242. Bernert JT, Pirkle JL, Xia Y, Jain RB, Ashley DL, Sampson EJ (November 2010). "Urine concentrations
Passive_smoking
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Glycerol
American college football season
touchdowns, two interceptions, and a 62.1 quarterback rating. End Mike Pirkle was the team's leading receiver with 72 receiving yards on four catches
1961 North Texas State Eagles football team
1961_North_Texas_State_Eagles_football_team
Hemorrhage Velvert Turner 49 December 11, 2000 Brooklyn, New York, U.S. Pirkle Lee Moses The El Dorados 63 December 16, 2000 Chicago, Illinois, U.S. Cancer
List of 2000s deaths in popular music
List_of_2000s_deaths_in_popular_music
Schiffman S, Shaw E, Bajwa SS, Reddy KN, Kirakossian H, Patkos GB, Theodor I, Pirkle H (March 1982). "Kallikrein-like activity of crotalase, a snake venom enzyme
Venombin_A
Sugar alcohol used as a sweetener
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Maltitol
American college baseball season
vs Akron Ting Stadium • Holly Springs, North Carolina 13–0 Iwinski (1–0) Pirkle (0–1) None 554 7–4 – 12 March 5 vs Akron Ting Stadium • Holly Springs, North
2023 Purdue Boilermakers baseball team
2023_Purdue_Boilermakers_baseball_team
American chemist
; Murali, S.; Stoller, M. D.; Ganesh, K. J.; Cai, W.; Ferreira, P. J.; Pirkle, A.; Wallace, R. M.; Cychosz, K. A.; Thommes, M.; Su, D.; Stach, E. A.;
Rodney_S._Ruoff
Chemical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Tryptophol
American college soccer season
Defenders 5 Julia Laskaris – Senior 7 Caroline Brooks – Freshman 11 Brooke Pirkle – Senior 18 Reagan Swindall – Sophomore 19 Margot Reemtsen – Freshman (F)
2020 Arkansas Razorbacks women's soccer team
2020_Arkansas_Razorbacks_women's_soccer_team
Pharmaceutical compound
Cyclopentanol Cyclopropanol Diphenylmethanol Isopropanol Pinacolyl alcohol Pirkle's alcohol Propylene glycol methyl ether Tertiary alcohols (3°) 2-Methyl-2-pentanol
Policosanol
PIRKLE
PIRKLE
PIRKLE
PIRKLE
PIRKLE
PIRKLE
PIRKLE
PIRKLE
PIRKLE