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PPM1D

  • PPM1D
  • Protein-coding gene in the species Homo sapiens

    Protein phosphatase 1D is an enzyme that in humans is encoded by the PPM1D gene. The protein encoded by this gene is a member of the PP2C family of Ser/Thr

    PPM1D

    PPM1D

    PPM1D

  • Clonal hematopoiesis
  • Expansion of blood cells

    components (SF3B1 and SRSF2), or members of the DNA damage response (TP53 and PPM1D). Many people identified as having clonal hematopoiesis have a mutation

    Clonal hematopoiesis

    Clonal_hematopoiesis

  • Margaret Goodell
  • American scientist

    Staff". Blood. August 30, 2024. Retrieved August 30, 2024. Globe and Mail "PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy"

    Margaret Goodell

    Margaret Goodell

    Margaret_Goodell

  • Cyclin O
  • Protein-coding gene in the species Homo sapiens

    Appella E, Donehower LA (August 2004). "The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair"

    Cyclin O

    Cyclin O

    Cyclin_O

  • Protein phosphatase
  • Class of enzymes

    DULLARD EPM2A ILKAP MDSP PGAM5 PHLPP1, PHLPP2 PPEF1, PPEF2 PPM1A, PPM1B, PPM1D, PPM1E, PPM1F, PPM1G, PPM1H, PPM1J, PPM1K, PPM1L, PPM1M, PPM1N PPTC7 PTPMT1

    Protein phosphatase

    Protein_phosphatase

  • CDC5L
  • Protein-coding gene in humans

    with: ASF/SF2, BZW1, CWC15, DNA-PKcs, DYNC1H1, GCN1L1, HSPA8, ILF2, PLRG1, PPM1D, PPP1CA, PRPF19, RBMX and RPL12, RPL13, RPS16, RPS25, SF3A1, SF3B1, SF3B2

    CDC5L

    CDC5L

    CDC5L

  • List of human protein-coding genes 6
  • O60437 12628 PPM1A HGNC:9275; P35813 12629 PPM1B HGNC:9276; O75688 12630 PPM1D HGNC:9277; O15297 12631 PPM1E HGNC:19322; Q8WY54 12632 PPM1F HGNC:19388;

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

  • Charles Brenner (biochemist)
  • American biologist

    ÁM; Nazarian, J; Berens, ME; Brenner, C; Bindra, RS (22 August 2019). "PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity

    Charles Brenner (biochemist)

    Charles_Brenner_(biochemist)

  • List of OMIM disorder codes
  • 113650; EYA1 Branchiootorenal syndrome; 113650; EYA1 Breast cancer; 114480; PPM1D Breast cancer; 114480; SLC22A1L Breast cancer; 114480; TP53 Breast cancer

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

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