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Protein found in humans
damage-inducible protein (GADD34), is a protein that in humans is encoded by the PPP1R15A gene. The Gadd34/MyD116 gene was originally discovered as a member in a
PPP1R15A
Protein-coding gene in the species Homo sapiens
shown to interact with: ASH2L, CREBBP, CTBP1, HDAC1, HCFC1, MEN1, PPIE, PPP1R15A, RBBP5, and WDR5. KMT2A rearrangements GRCh38: Ensembl release 89: ENSG00000118058
KMT2A
Class of enzymes
subunit 14: PPP1R14A, PPP1R14B, PPP1R14C, PPP1R14D regulatory subunit 15: PPP1R15A, PPP1R15B regulatory subunit 16: PPP1R16A, PPP1R16B As described earlier
Protein_phosphatase_1
Protein-coding gene in the species Homo sapiens
translocation in lymphoid neoplasms. Translin has been shown to interact with PPP1R15A. GRCh38: Ensembl release 89: ENSG00000211460 – Ensembl, May 2017 GRCm38:
Translin
Cellular stress response
growth arrest and DNA damage‐inducible protein (GADD34), also known as PPP1R15A, or constitutive repressor of eIF2α phosphorylation (CReP), also known
Integrated_stress_response
Enzyme
1, BCL2L2, BRCA1, CDC5L, Host cell factor C1, KvLQT1, LMTK2, PHACTR3, PPP1R15A, PPP1R8, PPP1R9B, Protein kinase R, and SMARCB1. GRCh38: Ensembl release
PPP1CA
Protein-coding gene in the species Homo sapiens
Cyclin-dependent kinase 8, Myc, P53, POLR2A, PPP1CA, PPP1CB, PPP1CC, PPP1R15A, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SS18, and XPO1. ENSG00000275837 GRCh38:
SMARCB1
Protein-coding gene in the species Homo sapiens
distinct isoforms have been observed. PPP1CB has been shown to interact with PPP1R15A, Nucleolin, SMARCB1 and PPP1R9B. GRCh38: Ensembl release 89: ENSG00000213639
PPP1CB
Protein-coding gene in the species Homo sapiens
receptor, C-Raf, Calcitriol receptor, Glucocorticoid receptor, HSPA8, HBEGF, PPP1R15A, NR1B1, and SIAH1. GRCh38: Ensembl release 89: ENSG00000107262 – Ensembl
BAG1
Mammalian protein found in Homo sapiens
CD22, Cdk1, DOK1, EPOR GPVI, INPP5D, IRS1, LCP2, MUC1, NEDD9, PLCG2, PPP1R15A, PTPRC, Syk, TRPV4, UNC119, Lyn-CD22-SHP-1 pathway GRCh38: Ensembl release
LYN
Protein-coding gene in the species Homo sapiens
is encoded by the PPP1CC gene. PPP1CC has been shown to interact with PPP1R15A, SMARCB1, TLX1 and PPP1R9B. GRCh38: Ensembl release 89: ENSG00000186298
PPP1CC
Neurological disease researcher
(September 2017). "Decoding the selectivity of eIF2α holophosphatases and PPP1R15A inhibitors". Nature Structural & Molecular Biology. 24 (9): 708–716. doi:10
Anne_Bertolotti
12671 PPP1R14C HGNC:14952; Q8TAE6 12672 PPP1R14D HGNC:14953; Q9NXH3 12673 PPP1R15A HGNC:14375; O75807 12674 PPP1R15B HGNC:14951; Q5SWA1 12675 PPP1R16A HGNC:14941;
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
PPP1R15A
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