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Protein-coding gene in the species Homo sapiens
subunit gamma isoform (PP2BC) is an enzyme that in humans is encoded by the PPP3CC gene. Calmodulin-dependent protein phosphatase, calcineurin, is involved
PPP3CC
Area of study for clinical research
mutants have less aggressive behaviours and have olfactory abnormalities. PPP3CC is a gene in which mutations are risk factors for schizophrenia; knockout
Animal_model_of_schizophrenia
Class of enzymes
catalytic subunit, each encoded by a separate gene (PPP3CA, PPP3CB, and PPP3CC) and two isoforms of the regulatory, also encoded by separate genes (PPP3R1
Calcineurin
Protein-coding gene in Homo sapiens
manner. Murine Ube3b ubiquitinated the catalytic γ-subunit of calcineurin, Ppp3cc, the overexpression of which phenocopied Ube3b loss with regard to dendrite
Ubiquitin-protein_ligase_E3B
Risk factors related to schizophrenia
neuregulin (NRG1), and that a number of other genes (such as COMT, RGS4, PPP3CC, ZDHHC8, DISC1, and AKT1) showed some early promising results. Knockout
Risk_factors_of_schizophrenia
Q16537 12702 PPP3CA HGNC:9314; Q08209 12703 PPP3CB HGNC:9315; P16298 12704 PPP3CC HGNC:9316; P48454 12705 PPP3R1 HGNC:9317; P63098 12706 PPP3R2 HGNC:9318;
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Class of enzymes
activity include: PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, PPP3CA, PPP3CB, PPP3CC, PPP4C PPP5C, PPP6C CDC14s: CDC14A, CDC14B, CDC14C, CDKN3 Phosphatase and
Protein_phosphatase
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