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PTPN1

  • PTPN1

    • Protein-coding gene in the species Homo sapiens

    protein tyrosine phosphatase (PTP) family. In humans it is encoded by the PTPN1 gene. PTP1B is a negative regulator of the insulin signaling pathway and

    PTPN1

    PTPN1

    PTPN1

  • Epidermal growth factor receptor

    • Transmembrane protein

    DCN, EGF, GRB14, Grb2, JAK2, MUC1, NCK1, NCK2 PKC alpha, PLCG1, PLSCR1, PTPN1, PTPN11, PTPN6, PTPRK, SH2D3A, SH3KBP1, SHC1, SOS1, Src, STAT1, STAT3, STAT5A

    Epidermal growth factor receptor

    Epidermal growth factor receptor

    Epidermal_growth_factor_receptor

  • Brunangelo Falini

    • Italian hematologist, academic and researcher

    tumor cells discovered recurrent mutations of STAT3, STAT5B, JAK1, JAK2 and PTPN1 that support the pivotal role of aberrant activation of JAK-STAT signalling

    Brunangelo Falini

    Brunangelo Falini

    Brunangelo_Falini

  • GRB2

    • Protein-coding gene in the species Homo sapiens

    9, NCKIPSD, NEU3, PDGFRB, PIK3R1, PLCG1, PRKAR1A, PTK2, PTPN11, PTPN12, PTPN1, PTPN6, PTPRA, RAPGEF1, RET proto-oncogene, SH2B1, SH3KBP1, SHC1, SOS1,

    GRB2

    GRB2

    GRB2

  • Insulin receptor substrate 1

    • Protein found in humans

    Bcl-2, Grb2, INSR, IGF1R, JAK1, JAK2, MAPK8, PIK3R1 PIK3R3, PTK2, PTPN11, PTPN1, and YWHAE. IRS-1, as a signalling adapter protein, is able to integrate

    Insulin receptor substrate 1

    Insulin receptor substrate 1

    Insulin_receptor_substrate_1

  • List of human protein-coding genes 6

    • Q15257 13128 PTPDC1 HGNC:30184; A2A3K4 13129 PTPMT1 HGNC:26965; Q8WUK0 13130 PTPN1 HGNC:9642; P18031 13131 PTPN2 HGNC:9650; P17706 13132 PTPN3 HGNC:9655; P26045

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

  • PTPN2

    • Protein-coding gene in the species Homo sapiens

    Baumgartner, CK, Ebrahimi-Nik, H, Iracheta-Vellve, A (2023). "The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity". Nature. 622

    PTPN2

    PTPN2

    PTPN2

  • Mirela Delibegovic

    • British virologist

    the American Heart Association personal fellowship to study the role of PTPN1 in glucose homeostasis at the Harvard Medical School in Boston, USA. She

    Mirela Delibegovic

    Mirela_Delibegovic

  • PILRA

    • Protein-coding gene in the species Homo sapiens

    has many known protein-protein interactions. PILRalpha recruits PTPN6 and PTPN1 via interactions of its ITIM motifs. PILRalpha is also used by some viruses

    PILRA

    PILRA

    PILRA

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