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DNA locus associated with variation in a quantitative trait
A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of
Quantitative_trait_locus
Genomic loci that explain variation in gene expression levels
An expression quantitative trait locus (eQTL) is a type of quantitative trait locus (QTL), a genomic locus (region of DNA) that is associated with phenotypic
Expression quantitative trait loci
Expression_quantitative_trait_loci
Member of a group of interacting genes
locate candidate genes for the trait. In the case that such a gene is identified, it is referred to as a quantitative trait locus (QTL). These genes are generally
Polygene
Genetic trait
architecture of complex traits has been explored using statistical approaches such as genome-wide association studies (GWAS) and quantitative trait loci (QTL) mapping
Complex_traits
Genetic loci that regulate pre-mRNA splicing
Splicing quantitative trait loci (abbreviated sQTLs or splicing QTLs) are quantitative trait loci that regulate alternative splicing of pre-mRNA. They
Splicing quantitative trait loci
Splicing_quantitative_trait_loci
Indirect selection process in breeding
the gene or quantitative trait locus (QTL) of interest, due to genetic linkage (close proximity, on the chromosome, of the marker locus and the disease
Marker-assisted_selection
Location of a gene or region on a chromosome
process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association mapping, also known as
Locus_(genetics)
Genome regions affecting protein levels
Protein quantitative trait loci (pQTL) are regions in the genome associated with variation in protein expression levels. Since proteins are the primary
Protein quantitative trait loci
Protein_quantitative_trait_loci
Genetic element in the species Homo sapiens
Bone mineral density quantitative trait locus 8 is a protein that in humans is encoded by the BMND8 gene. "Human PubMed Reference:". National Center for
Bone mineral density quantitative trait locus 8
Bone_mineral_density_quantitative_trait_locus_8
Type of genetic selection favoring one extreme phenotype
environmental factors and plays a major role in speciation. Analysis on quantitative trait locus (QTL) effects has been used to examine the impact of directional
Directional_selection
Protein-coding gene in the species Homo sapiens
is in the last 76 amino acids (89% homology) of both proteins. Quantitative trait locus: Primates, chimp and gibbon, represented the closest group of orthologous
FAM193A
Link between a disease and the causal genetic entity
A quantitative trait (see quantitative trait locus) is a measurable trait that shows continuous variation, such as height or weight. Quantitative traits
Genetic_association
(May 2004). "Quantitative trait locus mapping based on resampling in a vast maize testcross experiment and its relevance to quantitative genetics for
Genomic_selection
between a genetic locus and a phenotype. It is commonly used during genetic association studies, including quantitative trait locus (QTL) analyses and
Fine-mapping
Study of the inheritance of continuously variable traits
Quantitative genetics is the study of quantitative traits, which are phenotypes that vary continuously—such as height or mass—as opposed to phenotypes
Quantitative_genetics
interval mapping (ICIM) has been proposed as an approach to QTL (quantitative trait locus) mapping for populations derived from bi-parental crosses. QTL
Inclusive composite interval mapping
Inclusive_composite_interval_mapping
Sequence of DNA that determines traits in an organism
gene prediction software Lists of human genes Predictive medicine Quantitative trait locus Selfish genetic element Whole genome sequencing Orgogozo V, Peluffo
Gene
Swiss neuroscientist (born 1978)
groundbreaking work including the discovery of the first methylation quantitative trait locus associated with Alzheimer's disease, and the identification of
Johannes_Gräff
Dependence of a gene mutation's phenotype on mutations in other genes
Interactome (Genetic interaction network) Mutation Pleiotropy Quantitative trait locus Synthetic lethality Synthetic viability Neil A. Campbell, Jane
Epistasis
American-Israeli agricultural geneticist (1931–2026)
University of Illinois and elsewhere. Soller was the originator of quantitative trait locus mapping and marker-assisted selection. He began noticing the statistical
Morris_Soller
Genetic disease resulting in abnormal formation or function of cilia
challenging. Advances in genetic technologies, such as expression quantitative trait locus (eQTL) analysis, are helping to clarify the molecular mechanisms
Ciliopathy
Person with an elevated taste response
Drayna, Dennis (2003-02-21). "Positional Cloning of the Human Quantitative Trait Locus Underlying Taste Sensitivity to Phenylthiocarbamide". Science.
Supertaster
Human chromosome
factor-like protein 6-interacting protein 1 ARMC5 BMIQ5: Body mass index quantitative trait locus 5 C16orf58: encoding protein Chromosome 16 open reading frame 58
Chromosome_16
contains an integrated set of tools including genome, synteny and quantitative trait locus browsers for exploring genetic data. Expression tools include an
Popgenie
Subdiscipline of ecology
than expected. A quantitative trait locus (QTL) refers to a suite of genes that controls a quantitative trait. A quantitative trait is one that is influenced
Molecular_ecology
Variant of polymerase chain reaction
technology has many applications in quality control (QC) genotyping, quantitative trait locus (QTL) mapping, marker-assisted selection (MAS), and allele mining
Kompetitive allele specific PCR
Kompetitive_allele_specific_PCR
the trait of interest directly, or (b) are linked to/ in linkage disequilibrium with a quantitative trait locus (QTL) that contributes to the trait of
Association_mapping
Statistical methods for testing associations between rare genetic variants and phenotypes
Genome-wide association study Genetic association Kernel method Quantitative trait locus Whole genome sequencing Exome sequencing Li, Bingshan; Leal, Suzanne
Rare variant association testing
Rare_variant_association_testing
Application of statistical techniques to biological systems
measurable trait, a quantitative trait, that is under polygenic control. A genome region that is responsible for a continuous trait is called a quantitative trait
Biostatistics
Estimation of effect of genetic variation on phenotypic variation of a trait
human traits result from a combination of causes. If these causes interact, it is impossible to assign quantitative values to the fraction of a trait due
Heritability
One gene variant masking the effect of another in the other copy of the gene
describe gene variants on non-sex chromosomes (autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant
Dominance_(genetics)
Field that examines the role of genetic and environmental influences on human behaviour
environmental factors on characteristics and their evolution across time. Quantitative trait locus (QTL) analysis is a statistical approach for attempting to explain
Human_behaviour_genetics
Study of genes and heredity in plants
mechanisms that control complex traits, making it an ideal system for functional genomics, quantitative trait locus (QTL) mapping, and genetic improvement
Plant_genetics
Personality model consisting of five broad dimensions
In psychology and psychometrics, the Big Five personality trait model or five-factor model (FFM), sometimes called by the mnemonic acronym OCEAN or CANOE
Big_Five_personality_traits
Genetic characteristic
genetics Gene-environment correlation Eugenics Allergy Oncogene Quantitative trait locus Genetic privacy Genetic discrimination Gomes, Julia do Amaral;
Genetic_predisposition
Range of possible values for any characteristic of human beings
physical appearance Mendelian traits in humans Quantitative trait locus Human behaviour genetics Big Five personality traits "Human variation -- an introduction
Human_variability
Genetic marker commonly used in human genetics investigations
sensitivity is very likely a complex Mendelian trait whose variance is overwhelmingly dependent on a single gene locus; however, it is likely that a few other
PTC_tasting
Chemical compound
M, Risch N, Drayna D (2003). "Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide". Science.
Phenylthiocarbamide
Protein-coding gene in the species Homo sapiens
L, Garcia-Esparcia P, Vidal E, et al. (May 2018). "PM20D1 is a quantitative trait locus associated with Alzheimer's disease". Nature Medicine. 24 (5):
PM20D1
phenotypic values to specific genotypes and gene products. quantitative trait quantitative trait locus (QTL) quantum evolution A rapid evolutionary shift in
Glossary of genetics and evolutionary biology
Glossary_of_genetics_and_evolutionary_biology
Topics referred to by the same term
intended article. The acronym QTLS might refer to: Qualified Teacher Learning and Skills, an award for teachers quantitative trait locus, a section of DNA
QTLS
Single nucleotide in genomic DNA at which different sequence alternatives exist
alter the level of expression of a gene, as an eQTL (expression quantitative trait locus). SNPs in coding regions: synonymous substitutions by definition
Single-nucleotide polymorphism
Single-nucleotide_polymorphism
DNA profiling tool
within populations, and in linkage studies to generate maps for quantitative trait locus (QTL) analysis. There are many advantages to AFLP when compared
Amplified fragment length polymorphism
Amplified_fragment_length_polymorphism
Species of grass
PMC 1206392. PMID 7713443. Latta, RG; Gardner, KM; Staples, DA (2010). "Quantitative trait locus mapping of genes under selection across multiple years and sites
Avena_barbata
Medical condition
may be related to macular retinal edema and intraocular pressure quantitative trait locus. With the lack of research and understanding about this specific
Tenonitis
Canadian neuroscientist (born 1966)
press, including an episode of the TED Radio Hour. Using both quantitative trait locus mapping and genetic association study (including GWAS) techniques
Jeffrey_Mogil
Laboratory process
Error in the mendelian inheritance Quantitative trait locus – DNA locus associated with variation in a quantitative trait SNP genotyping – Measurement of
Genotyping
Individuals nearly identical in genotype due to long inbreeding
a quantitative trait locus analysis. The replication increases the precision of the results from the mapping experiment, and is required for traits such
Inbred_strain
British evolutionary biologist
reconstruction, inbreeding depression, parasite resistance, and quantitative trait locus (QTL) detection in natural populations. She has worked primarily
Josephine_Pemberton
Effect when genes source into a phenotype
regard to quantitative traits, as the sum of these effects informs the placement of a trait on the spectrum of possible outcomes. Quantitative traits are commonly
Additive_genetic_effects
Basal organ of a vascular plant
Liu, Dan; Pedersen, Ole; Sauter, Margret (11 January 2023). "A quantitative trait locus conferring flood tolerance to deepwater rice regulates the formation
Root
Quantitative genetic model developed by Ronald Fisher in 1918
1918 by Ronald Fisher, it is based on the idea that variation in a quantitative trait is influenced by an infinitely large number of genes, each of which
Infinitesimal_model
Protein-coding gene in the species Homo sapiens
region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level[citation needed], and
HBS1-like_protein
American geneticist
Drayna, Dennis (2003-02-21). "Positional Cloning of the Human Quantitative Trait Locus Underlying Taste Sensitivity to Phenylthiocarbamide". Science.
Dennis_Drayna
German breed of horse
Distl (2008). Associations between Candidate Gene Markers at a Quantitative Trait Locus on Equine Chromosome 4 Responsible for Osteochondrosis Dissecans
South_German_Coldblood
Protein-coding gene in the species Homo sapiens
linked to epithelial homeostasis. Another found it to be in a quantitative trait locus linked to haloperidol-induced catalepsy. TMEM63A has two paralogs:
TMEM63A
Gene that has the potential to cause cancer
Oncogenomics Tumor suppressor gene Oncovirus Genetic predisposition Quantitative trait locus Genetic susceptibility Oncometabolism Becker, Wayne M.; Kleinsmith
Oncogene
Protein-coding gene in the species Homo sapiens
N, Drayna D (February 2003). "Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide". Science.
TAS2R38
Protein-coding gene in the species Homo sapiens
Hashimoto K, Osumi N, Yoshikawa T (Nov 2007). "Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype". PLOS Biology. 5 (11): e297
FABP7
Fungal disease of wheat
most often abbreviated Yr and Yr1, Yr24, etc. QYr.niab-2D.1 is a quantitative trait locus (QTL) for adult plant resistance (APR). This allele comes from
Wheat_yellow_rust
American maize geneticist and plant breeder
302-line maize association population developed for high-resolution quantitative trait locus analysis. Goodman was elected to the National Academy of Sciences
Major_M._Goodman
(2010-10-01). "Detection of a quantitative trait locus for ham weight with polar overdominance near the ortholog of the callipyge locus in an experimental pig
Polar_overdominance
Process of locating specific genes
fingerprinting Genome project Human Genome Project Optical mapping Quantitative trait locus Sulston score Mader S (2007). Biology (Ninth ed.). New York: McGraw-Hill
Gene_mapping
PMC 408579. PMID 10525048. Kohara, Yuki (2001). "A major determinant quantitative-trait locus responsible for atopic dermatitis-like skin lesions in NC/Nga mice
Nc/Nga_mice_model
Concept in genetic epidemiology
Iwayama Y, Matsumata M, et al. (November 2007). "Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype". PLOS Biology. 5 (11): e297
Endophenotype
index for a single genetic locus (FST). QST is often compared with FST of neutral loci to test if variation in a quantitative trait is a result of divergent
QST_(genetics)
Oxygen carrier protein in the human fetus
S2CID 5500015. Hemosh A (9 September 2014). "FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1; HBFQTL1". OMIM. Johns Hopkins University. Retrieved 15 March
Fetal_hemoglobin
Ischemic bone disease
(March–April 2008). "Associations between candidate gene markers at a quantitative trait locus on equine chromosome 4 responsible for osteochondrosis dissecans
Osteochondritis_dissecans
Protein-coding gene in the species Homo sapiens
the HPFH KLF1-related condition and established KLF1 as a novel quantitative trait locus for HbF (HBFQTL6). Permissive nature of the role of KLF1 on expression
KLF1
PsycINFO Puer Aeternus Punishment Quantitative psychological research Quantitative psychology Quantitative trait locus Radical behaviorism Radical Psychology
Index_of_psychology_articles
Disorders from genes and environment combined
color of petals.[citation needed] Genetic disorders polygenes Quantitative trait locus Duarte, Christine W.; Vaughan, Laura K.; Beasley, T. Mark; Tiwari
Multifactorial_disease
Australian geneticist
Division of Forestry, where she undertook genetic mapping and quantitative trait locus (QTL) analysis in eucalypts. In 1996 she returned to Perth to establish
Margaret_Byrne
sequence; 208150; RAPSN Fetal hemoglobin quantitative trait locus 1; 141749; HBG1 Fetal hemoglobin quantitative trait locus 1; 141749; HBG2 FG syndrome 2; 300321;
List_of_OMIM_disorder_codes
computer mouse Barbara Engelhardt – latent variable models, genomics, quantitative trait locus (QTL) David Eppstein Andrey Ershov – languages ALPHA, Rapira; first
List_of_computer_scientists
Protein found in humans
DW, Kimberling WJ, Pennington BF, DeFries JC (October 1994). "Quantitative trait locus for reading disability on chromosome 6". Science. 266 (5183): 276–9
Dyslexia-associated_protein
American geneticist
genetic locus as a gene encoding the TAS1R3 taste receptor was the first successful positional cloning of a behavioral quantitative trait locus (QTL).
Alexander_Bachmanov
Passing of traits to offspring from the species' parents or ancestor
also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or
Heredity
Protein-coding gene in the species Homo sapiens
(September 2014). "SIRPB1 copy-number polymorphism as candidate quantitative trait locus for impulsive-disinhibited personality". Genes, Brain and Behavior
SIRPB1
Proportion of variance that two traits share due to genetic causes
"Variance components models for gene-environment interaction in quantitative trait locus linkage analysis". Twin Research. 5 (6): 572–6. doi:10.1375/136905202762342035
Genetic_correlation
small changes in allele frequencies at hundreds or thousands of loci. Many traits in humans and other species are highly polygenic, i.e., affected by standing
Polygenic_adaptation
Protein-coding gene in the species Homo sapiens
important for lactation, with quantitative trait locus (QTL) for several milk production and composition traits observed at this locus in cattle. GRCh38: Ensembl
GPAT4
Part of the genetic makeup of a cell which determines one of its characteristics
the pea plant. However, other traits are only partially influenced by genotype. These traits are often called complex traits because they are influenced
Genotype
Type of biological inheritance
processes. A Mendelian trait is one whose inheritance follows Mendel's principles—namely, the trait depends only on a single locus, whose alleles are either
Mendelian_inheritance
American professor of biology at Stanford University
of cis-regulatory divergence more efficiently than traditional quantitative trait locus (QTL) mapping approaches. Model organisms used by the lab span
Hunter_Fraser
Diagnostic framework in personalized psychiatry
multiple dimensions (e.g., cognition, mood, social interactions), with traits that exist on a continuum ranging from normal to extreme. Co-occurrence
Research_Domain_Criteria
Fungal disease of maize
2016 uses a near-isogenic line (NIL) to find Qgls8 . Qgls8 is a quantitative trait locus (QTL) for GLS resistance originally from the teosinte Zea parviglumis
Corn_grey_leaf_spot
Branch of psychology focused on personality
many different people, such as the principle of self-actualization or the traits of extraversion and introversion. Idiographic psychology is an attempt to
Personality_psychology
Enzyme found in humans
Skarić-Jurić T, Salihović MP, Klarić IM, Lauc LB, et al. (June 2009). "A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate". American
Prostacyclin_synthase
Mechanism of evolution by differential reproduction
than one direction. In particular, if the trait is quantitative and univariate then both higher and lower trait levels are favoured. Disruptive selection
Natural_selection
Genus of viruses
of resistance to the rice hoja blanca disease deciphered by a quantitative trait locus approach". G3. 13 (12). doi:10.1093/g3journal/jkad223. PMC 10700108
Tenuivirus
Gene considered likely to be involved in a condition
interest in the genome. Genome-wide association studies (GWAS) and quantitative trait locus (QTL) mapping examine common variation across the entire genome
Candidate_gene
Protein-coding gene in the species Homo sapiens
annotation of a 1.5 Mb region of human chromosome 6q23 encompassing a quantitative trait locus for fetal hemoglobin expression in adults". BMC Genomics. 5 (1)
AHI1
1918 scientific article by Ronald Fisher
formed the theoretical basis of population genetics and the study of quantitative traits. In 1918, Ronald A. Fisher published The Correlation Between Relatives
The Correlation between Relatives on the Supposition of Mendelian Inheritance
The_Correlation_between_Relatives_on_the_Supposition_of_Mendelian_Inheritance
Maize laboratory technique
"Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in maize". Proc. Natl. Acad. Sci. U.S.A. 104 (27): 11376–81. Bibcode:2007PNAS
Nested_association_mapping
British computational biologist
M. F.; Cookson, W. O. C. M. (2003). "Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and
Chris_Ponting
genetics responses affecting alcohol withdrawal and preference. Quantitative trait locus which relates gene expression to genotypes. Genetic analysis of
Alcoholic_beverages_in_Oregon
American Plant Biologist
T; Weitz, JS; Benfey, PN (April 30, 2013). "3D phenotyping and quantitative trait locus mapping identify core regions of the rice genome controlling root
Philip_Benfey
Personality trait of negativity
personality trait with disagreement on its definition, but widely understood to be associated with negative emotions. It is one of the Big Five traits. People
Neuroticism
Modelling evolution using differential equations
population dynamics. Where the evolution of continuous heritatable traits is studied quantitative genetics provides a means of understanding them in a mathematical
Evolutionary_dynamics
Mouse assay for heritable germline mutation
marker loci, classically seven, with visible traits such as altered coat color or short ears. The specific-locus test is an assay that uses mutagenesis of
Specific-locus_test
QUANTITATIVE TRAIT-LOCUS
QUANTITATIVE TRAIT-LOCUS
Boy/Male
Tamil
Lightning
Boy/Male
French
Surname with American connotations due to Laramie; a town in Wyoming USA on the Overland Trail of...
Boy/Male
Australian, British, English
Sparkle
Girl/Female
Muslim/Islamic
Good traits excellent disposition
Boy/Male
American, British, Celtic, Chinese, Christian, English, German, Hebrew, Indian, Irish, Jamaican
Narrow; Channel; Strait; Near the Chapel; A Place-name Referring to the Narrows; A Wood; A Church; Fair and Handsome; Crowned with Laurel; Victory; Slender
Girl/Female
American, Anglo, Australian, British, English, Polish
Pleasant and Bright; Brings Joy; Cheerful; Happy
Surname or Lastname
English
English : habitational name from Haveland in Membury, Devon, probably named in Old English with hæfer ‘he-goat’ + land ‘tract of land’, ‘estate’.
Surname or Lastname
English
English : variant of Straight.
Boy/Male
Norse Swedish English Irish Scandinavian
Happy.
Boy/Male
American, Anglo, Australian, British, English, Irish, Norse, Polish, Scandinavian
Happy; Measure of Land; Form of Tate; To be Cheerful
Male
Vietnamese
Vietnamese name TRAI means "oyster."
Girl/Female
Arabic, Muslim, Sindhi
Good Traits; Excellent Disposition
Girl/Female
Muslim
Good traits excellent disposition
Girl/Female
Arabic, Muslim
To Trail a Garment
Girl/Female
English Anglo Saxon
Brings joy.
Girl/Female
Muslim
To trail a garment
Surname or Lastname
English (Devon)
English (Devon) : metonymic occupational name for a trapper or hunter, from Middle English trayne, Old French traine ‘guile’, ‘snare’, ‘trap’.English (Devon) : topographic name from Middle English atte trewen ‘at the trees’, or a habitational name from any of the places named with this phrase, for example Train, Traine, or Trewyn, all in Devon.
Surname or Lastname
English (Devon)
English (Devon) : unexplained.Irish (County Kerry) : reduced form of Tramant, which MacLysaght describes as ‘a family of pre-Norman origin’.
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Lightning
Surname or Lastname
English
English : from Middle English trowte ‘trout’, hence a metonymic occupational name for a fisherman, or a nickname for someone supposedly resembling the fish.Altered spelling of German Traut.
QUANTITATIVE TRAIT-LOCUS
QUANTITATIVE TRAIT-LOCUS
Girl/Female
Australian, German, Swedish
Pearl
Girl/Female
Arabic, Muslim
Strong
Girl/Female
Hindu
Short name of Malavika
Girl/Female
Arabic, Australian, Muslim
Voice; Rhythm
Girl/Female
English French American Latin
Jewel.
Male
Portuguese
Galician-Portuguese form of Latin Stephanus, ESTEVO means "crown."
Boy/Male
Indian
Brilliant
Boy/Male
English American
From the Old English 'ceorl' meaning man.
Girl/Female
Hindu, Indian, Malayalam, Marathi
Ocean of Blood
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
All Knowing; Lord Vishnu
QUANTITATIVE TRAIT-LOCUS
QUANTITATIVE TRAIT-LOCUS
QUANTITATIVE TRAIT-LOCUS
QUANTITATIVE TRAIT-LOCUS
QUANTITATIVE TRAIT-LOCUS
v. t.
To draw along; to trail; to drag.
v.
A roll train; as, a 12-inch train.
n.
Anything drawn out to a length; as, the trail of a meteor; a trail of smoke.
n.
A track left by man or beast; a track followed by the hunter; a scent on the ground by the animal pursued; as, a deer trail.
v.
Regular method; process; course; order; as, things now in a train for settlement.
v. t.
To teach and form by practice; to educate; to exercise; to discipline; as, to train the militia to the manual exercise; to train soldiers to the use of arms.
v.
A region or quantity of land or water, of indefinite extent; an area; as, an unexplored tract of sea.
n.
Same as Strait-jacket.
n.
Anything drawn behind in long undulations; a train.
a.
A (comparatively) narrow passageway connecting two large bodies of water; -- often in the plural; as, the strait, or straits, of Gibraltar; the straits of Magellan; the strait, or straits, of Mackinaw.
v.
The after part of a gun carriage; the trail.
v.
A distinguishing or marked feature; a peculiarity; as, a trait of character.
v. i.
To prepare by exercise, diet, instruction, etc., for any physical contest; as, to train for a boat race.
a.
Estimable according to quantity; quantitative.
n.
A footpath or road track through a wilderness or wild region; as, an Indian trail over the plains.
v.
Traits; features; lineaments.
a.
Relating to quantity.
v.
Continuity or extension of anything; as, the tract of speech.