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See searches and references containing RAB8A!RAB8A
Protein-coding gene in the species Homo sapiens
Ras-related protein Rab-8A is a protein that in humans is encoded by the RAB8A gene. The protein encoded by this gene is a member of the RAS superfamily
RAB8A
Protein superfamily of small GTPases
RAB4B; RAB5A; RAB5B; RAB5C; RAB6A; RAB6B; RAB6C; RAB7A; RAB7B; RAB7L1; RAB8A; RAB8B; RAB9; RAB9B; RABL2A; RABL2B; RABL4; RAB10; RAB11A; RAB11B; RAB12;
Ras_superfamily
Membrane-bound organelle in cells containing fluid
Merrifield, Christien; Soldati, Thierry (April 2012). Brennwald, Patrick (ed.). "Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium
Vacuole
Protein found in humans
vasoconstriction. Optineurin has been shown to interact with Huntingtin and RAB8A. GRCh38: Ensembl release 89: ENSG00000123240 – Ensembl, May 2017 GRCm38:
Optineurin
Protein-coding gene in humans
FLCN-FNIP complex, which it resembles. In addition, the complex is a GAP for Rab8a and Rab11a, with cryo-EM identifying an arginine finger conserved between
C9orf72
Protein-coding gene in the species Homo sapiens
85.8% amino acid identity), the knockdown of any of them (from RAB1A to RAB8A) causes Golgi complex to disperse through the cell's cytoplasm. Because
RAB2B
Family of GTP-binding proteins
trans-Golgi network RAB6B RAB6C RAB6D RAB7 (Ypt7, RabS) Late endosomes, vacuoles RAB8A Basolateral secretory vesicles RAB8B RAB9A Late endosome, trans-golgi network
Rab_(G-protein)
Protein-coding gene in the species Homo sapiens
by Akt phosphorylation. Specifically, this inhibition activates RAB2A, RAB8A, RAB10 and RAB14. AS160 also contains a calmodulin-binding domain, and this
TBC1D4
Protein-coding gene in the species Homo sapiens
including 55 co-complex interactions. NDUFA10 appears to interact with RAB8A. GRCh38: Ensembl release 89: ENSG00000130414 – Ensembl, May 2017 GRCm38:
NDUFA10
Protein found in humans
preferentially interact with the GDP-bound form of the small GTPase RAB8A. RAB8A is involved in rhodopsin trafficking in primary cilia. The C-terminal
Retinitis pigmentosa GTPase regulator
Retinitis_pigmentosa_GTPase_regulator
transporting the CNGB1 protein which has a RVxP motif into human cilia, as is Rab8a in transporting PKD2. Not all ciliary proteins use a RVxP motif for transport
RVxP_motif
Protein-coding gene in humans
Hippo pathway effectors YAP and TAZ. MAP4K2 has been shown to interact with RAB8A and TRAF2. GRCh38: Ensembl release 89: ENSG00000168067 – Ensembl, May 2017
MAP4K2
Q53S08 13278 RAB7A HGNC:9788; P51149 13279 RAB7B HGNC:30513; Q96AH8 13280 RAB8A HGNC:7007; P61006 13281 RAB8B HGNC:30273; Q92930 13282 RAB9A HGNC:9792;
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Australian cell biologist
201001028. PMC 3101599. PMID 20837769. Luo L, Wall AA, Yeo JC, et al. (2014). "Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling"
Jennifer_Stow
Protein-coding gene in humans
CBY1 has also been shown to interact with CEP164, CIBAR1 (FAM92A1), and RAB8A. GRCh38: Ensembl release 89: ENSG00000100211 – Ensembl, May 2017 GRCm38:
Protein_chibby_homolog_1
Protein-coding gene in the species Homo sapiens
2017). "The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking". Hum. Mol
TMEM230
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