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RASGRP1

  • RASGRP1
  • Protein-coding gene in the species Homo sapiens

    guanyl-releasing protein 1 is a protein that in humans is encoded by the RASGRP1 gene. RAS guanyl nucleotide-releasing protein (RASGRP) is a member of a

    RASGRP1

    RASGRP1

    RASGRP1

  • SKAP1
  • Protein-coding gene in the species Homo sapiens

    Additional work has implicated SKAP1 in binding to the exchange factor RasGRP1 and in regulating ERK activation in T-cells. SKAP1 has been shown to interact

    SKAP1

    SKAP1

    SKAP1

  • Cation-chloride cotransporter
  • cotransporter cause the recessive Gitelman syndrome. It is regulated by RasGRP1. CCC plays a key role in chloride homeostasis. During the day, NKCC is

    Cation-chloride cotransporter

    Cation-chloride_cotransporter

  • C1 domain
  • Protein domain

    PRKCI; PRKCN; PRKCQ; PRKCZ; PRKD1; PRKD2; PRKD3; RACGAP1; RAF1; RASGRP; RASGRP1; RASGRP2; RASGRP3; RASGRP4; RASSF1; RASSF5; ROCK1; ROCK2; STAC; STAC2;

    C1 domain

    C1 domain

    C1_domain

  • EF hand
  • Protein helix–loop–helix motif

    PPEF1; PPEF2; PPP3R1; PPP3R2; PRKCSH; PVALB RAB11FIP3; RASEF; RASGRP; RASGRP1; RASGRP2; RASGRP3; RCN1; RCN2; RCN3; RCV1; RCVRN; REPS1; RHBDL3; RHOT1;

    EF hand

    EF hand

    EF_hand

  • Luk Van Parijs
  • American biologist

    B (2003) Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1. Immunity 19(2): 243-55 (August). PMID 12932358 (Retracted, see doi:10

    Luk Van Parijs

    Luk_Van_Parijs

  • PLCG1
  • Protein found in humans

    the encoded protein causes the Ras guanine nucleotide exchange factor RASGRP1 to translocate to the Golgi apparatus, where it activates Ras. Also, this

    PLCG1

    PLCG1

    PLCG1

  • RasGEF domain
  • Protein domain

    RAPGEF5; RAPGEF6; RAPGEFL1; RASGEF1A; RASGEF1B; RASGEF1C; RASGRF1; RASGRF2; RASGRP1; RASGRP2; RASGRP3; RASGRP4; RGL1; RGL2; RGL3; RGL4/RGR; SOS1; SOS2; Boriack-Sjodin

    RasGEF domain

    RasGEF domain

    RasGEF_domain

  • List of human protein-coding genes 6
  • 13446 RASGRF1 HGNC:9875; Q13972 13447 RASGRF2 HGNC:9876; O14827 13448 RASGRP1 HGNC:9878; O95267 13449 RASGRP2 HGNC:9879; Q7LDG7 13450 RASGRP3 HGNC:14545;

    List of human protein-coding genes 6

    List_of_human_protein-coding_genes_6

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