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SAREDUTANT

  • Saredutant

    • Chemical compound

    Saredutant (SR-48,968) is a drug that acts as a NK2 receptor antagonist. It was under development by Sanofi-Aventis as a novel antidepressant and anxiolytic

    Saredutant

    Saredutant

    Saredutant

  • Tradipitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Tradipitant

    Tradipitant

    Tradipitant

  • Tachykinin peptides

    • Protein family

    include: Aprepitant Casopitant Fosaprepitant Maropitant Nepadutant Osanetant Saredutant Talnetant Tachykinin InterPro: IPR008215 Grace RC, Lynn AM, Cowsik SM

    Tachykinin peptides

    Tachykinin peptides

    Tachykinin_peptides

  • Fezolinetant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Fezolinetant

    Fezolinetant

    Fezolinetant

  • Elinzanetant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Elinzanetant

    Elinzanetant

    Elinzanetant

  • Substance P

    • Chemical compound (polypeptide neurotransmitter)

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Substance P

    Substance P

    Substance_P

  • Maropitant

    • Veterinary medication

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Maropitant

    Maropitant

    Maropitant

  • List of drugs: S–Sd

    • (USAN, INN) Sarafem sarafloxacin (INN) saralasin (INN) sarcolysin (INN) saredutant (INN) Sarenin sargramostim (INN) sarilumab (USAN) saripidem (INN) Sarisol

    List of drugs: S–Sd

    List_of_drugs:_S–Sd

  • Casopitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Casopitant

    Casopitant

    Casopitant

  • NK1 receptor antagonist

    • Chemical compound class

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    NK1 receptor antagonist

    NK1_receptor_antagonist

  • Netupitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Netupitant

    Netupitant

    Netupitant

  • Aprepitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Aprepitant

    Aprepitant

    Aprepitant

  • Pavinetant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Pavinetant

    Pavinetant

    Pavinetant

  • Rolapitant

    • Pharmaceutical drug

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Rolapitant

    Rolapitant

    Rolapitant

  • Lanepitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Lanepitant

    Lanepitant

    Lanepitant

  • Tachykinin receptor 1

    • Protein-coding gene in the species Homo sapiens

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Tachykinin receptor 1

    Tachykinin receptor 1

    Tachykinin_receptor_1

  • Osanetant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Osanetant

    Osanetant

    Osanetant

  • List of investigational antidepressants

    • List of pharmaceutical drugs under clinical development for treatment of depression

    CEB-242; Memric; SB-202026) – muscarinic acetylcholine M1 receptor agonist Saredutant (SR-48968) – neurokinin NK2 receptor antagonist SB-236057 – serotonin

    List of investigational antidepressants

    List_of_investigational_antidepressants

  • Netupitant/palonosetron

    • Pharmaceutical drug

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Netupitant/palonosetron

    Netupitant/palonosetron

  • Tachykinin receptor 2

    • Protein-coding gene in the species Homo sapiens

    compounds developed so far are peptides, one small-molecule antagonist Saredutant is currently in clinical trials as an anxiolytic and antidepressant. GR-64349

    Tachykinin receptor 2

    Tachykinin receptor 2

    Tachykinin_receptor_2

  • Vofopitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Vofopitant

    Vofopitant

    Vofopitant

  • Burapitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Burapitant

    Burapitant

    Burapitant

  • Orvepitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Orvepitant

    Orvepitant

    Orvepitant

  • Nepadutant

    • Chemical compound

    gastrointestinal disorders and asthma but was never marketed. GR-159,897 Ibodutant Saredutant Annual Reports in Medicinal Chemistry. Academic Press. 8 September 1999

    Nepadutant

    Nepadutant

    Nepadutant

  • Vestipitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Vestipitant

    Vestipitant

    Vestipitant

  • Serlopitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Serlopitant

    Serlopitant

    Serlopitant

  • Talnetant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Talnetant

    Talnetant

    Talnetant

  • Fosaprepitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Fosaprepitant

    Fosaprepitant

    Fosaprepitant

  • GR-159897

    • Chemical compound

    potentially make it useful in the treatment of asthma. Ibodutant Nepadutant Saredutant Beresford IJ, Sheldrick RL, Ball DI, Turpin MP, Walsh DM, Hawcock AB,

    GR-159897

    GR-159897

    GR-159897

  • Neurokinin A

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Neurokinin A

    Neurokinin A

    Neurokinin_A

  • Tachykinin receptor 3

    • Protein-coding gene in the species Homo sapiens

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Tachykinin receptor 3

    Tachykinin receptor 3

    Tachykinin_receptor_3

  • Neurokinin B

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Neurokinin B

    Neurokinin B

    Neurokinin_B

  • Ibodutant

    • Chemical compound

    response and negative results of study NAK-06. GR-159,897 Nepadutant Saredutant "Clinical Trials Database". Menarini Group. Retrieved 11 March 2015. Spreitzer

    Ibodutant

    Ibodutant

    Ibodutant

  • L-733,060

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    L-733,060

    L-733,060

    L-733,060

  • Ezlopitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Ezlopitant

    Ezlopitant

    Ezlopitant

  • Tachykinin receptor

    • InterPro Family

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Tachykinin receptor

    Tachykinin_receptor

  • Befetupitant

    • Chemical compound

    NK2 Agonists: Neurokinin A Antagonists: GR-159897 Ibodutant Nepadutant Saredutant Otilonium bromide NK3 Agonists: Neurokinin B Senktide Antagonists: Elinzanetant

    Befetupitant

    Befetupitant

    Befetupitant

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