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SEPTIN

  • Septin
  • Family of proteins

    Septins are a group of GTP-binding proteins expressed in all eukaryotic cells except plants. Different septins form protein complexes with each other.

    Septin

    Septin

  • Cytoskeleton
  • Network of filamentous proteins that forms the internal framework of cells

    function in consciousness. Septins are a group of the highly conserved GTP binding proteins found in eukaryotes. Different septins form protein complexes

    Cytoskeleton

    Cytoskeleton

    Cytoskeleton

  • Septin-4
  • Protein-coding gene in the species Homo sapiens

    Septin-4 is a protein that in humans is encoded by the gene SEPTIN4 (previously SEPT4). The gene is 2,698 base pairs long, contains one gt-ag intron, and

    Septin-4

    Septin-4

    Septin-4

  • SEPTIN3
  • Protein-coding gene in the species Homo sapiens

    Neuronal-specific septin-3 is a protein that in humans is encoded by the SEPTIN3 gene (previously SEPT3). This gene belongs to the septin family of GTPases

    SEPTIN3

    SEPTIN3

    SEPTIN3

  • SEPTIN9
  • Protein-coding gene in the species Homo sapiens

    Septin-9 is a protein that in humans is encoded by the SEPTIN9 gene (previously SEPT9). SEPT9 has been shown to interact with SEPT2 and SEPT7. Along with

    SEPTIN9

    SEPTIN9

    SEPTIN9

  • Fluid mosaic model
  • Model of cell membranes

    extracellular matrix outside the cell, cytoskeleton filaments inside the cell, and septin ring-like structures. These interactions have a strong influence on shape

    Fluid mosaic model

    Fluid mosaic model

    Fluid_mosaic_model

  • Septin-12
  • Protein-coding gene in the species Homo sapiens

    Septin-12 is a protein that in humans is encoded by the SEPTIN12 gene (previously SEPT12). This gene encodes a guanine-nucleotide binding protein and member

    Septin-12

    Septin-12

    Septin-12

  • Septin-14
  • Protein-coding gene in the species Homo sapiens

    Septin-14 is a protein that in humans is encoded by the SEPTIN14 gene (previously SEPT14). SEPT14 is a member of the highly conserved septin family of

    Septin-14

    Septin-14

    Septin-14

  • SEPTIN5
  • Protein-coding gene in the species Homo sapiens

    Septin-5 is a protein that in humans is encoded by the SEPTIN5 gene (previously SEPT5). This gene is a member of the septin gene family of nucleotide

    SEPTIN5

    SEPTIN5

    SEPTIN5

  • Septin-10
  • Protein-coding gene in the species Homo sapiens

    Septin-10 is a protein that in humans is encoded by the SEPTIN10 gene (previously SEPT10). This gene encodes a member of the septin family of cytoskeletal

    Septin-10

    Septin-10

    Septin-10

  • SEPTIN6
  • Protein-coding gene in the species Homo sapiens

    Septin-6 is a protein that in humans is encoded by the SEPTIN6 gene (previously SEPT6). This gene is a member of the septin family of GTPases. Members

    SEPTIN6

    SEPTIN6

    SEPTIN6

  • SEPTIN2
  • Protein-coding gene in the species Homo sapiens

    Septin-2 (also known as SEPT2) is a protein which in humans is encoded by the SEPTIN2 gene (previously SEPT2). SEPT2 can hetero-oligomerize with SEPT6

    SEPTIN2

    SEPTIN2

    SEPTIN2

  • Saccharomyces cerevisiae
  • Species of yeast

    the septin ring forms an hourglass. The septin hourglass and the myosin ring together are the beginning of the future division site. The septin and AMR

    Saccharomyces cerevisiae

    Saccharomyces cerevisiae

    Saccharomyces_cerevisiae

  • Septum
  • Biological term for a wall dividing a cavity or structure

    Septins in Saccharomyces cerevisiae

    Septum

    Septum

  • SEPTIN7
  • Protein-coding gene in the species Homo sapiens

    Septin-7 is a protein that in humans is encoded by the SEPTIN7 gene (previously SEPT7). This gene encodes a protein that is highly similar to the CDC10

    SEPTIN7

    SEPTIN7

    SEPTIN7

  • ANLN
  • Mammalian protein found in Homo sapiens

    anillin and septins was first shown by the interaction seen between Xenopus anillin and a minimal reconstituted heterooligomer of human septins 2, 6, and

    ANLN

    ANLN

    ANLN

  • SEPTIN11
  • Protein-coding gene in the species Homo sapiens

    Septin-11 is a protein that in humans is encoded by the SEPTIN11 gene (previously SEPT11). GRCh38: Ensembl release 89: ENSG00000138758 – Ensembl, May 2017

    SEPTIN11

    SEPTIN11

    SEPTIN11

  • SEPTIN8
  • Protein-coding gene in the species Homo sapiens

    Septin-8 is a protein that in humans is encoded by the SEPTIN8 gene (previously SEPT8). SEPT8 is a member of the highly conserved septin family. Septins

    SEPTIN8

    SEPTIN8

    SEPTIN8

  • Microsoft Excel
  • Spreadsheet editor by Microsoft

    Ring-CH-type finger 1) gets converted to the date March 1 (1-Mar) and SEPT2 (Septin 2) is converted into September 2 (2-Sep) etc. While some secondary news

    Microsoft Excel

    Microsoft Excel

    Microsoft_Excel

  • SEPT4
  • Protein-coding gene in the species Homo sapiens

    Septin-4 is a protein that in humans is encoded by the SEPTIN4 gene (previously SEPT4). This gene is a member of the septin gene family of nucleotide

    SEPT4

    SEPT4

    SEPT4

  • Amy Gladfelter
  • American cell biologist (born 1974)

    innovative reconstitution assays to study septin filament dynamics on membranes.  Her lab discovered septin filaments sense local cell curvature on the

    Amy Gladfelter

    Amy Gladfelter

    Amy_Gladfelter

  • Alternating electric field therapy
  • Type of electromagnetic field therapy

    α/β-tubulin and the mitotic septin heterotrimer. Tubulin is necessary for mitotic spindle formation during metaphase, while septins stabilize the cell during

    Alternating electric field therapy

    Alternating_electric_field_therapy

  • Shigella flexneri
  • Species of bacterium

    also septins by inducing their ubiquitination compared to non-infected state. This ubiquitination prevents them from forming higher filamentous septin structures

    Shigella flexneri

    Shigella flexneri

    Shigella_flexneri

  • SEPTIN1
  • Protein-coding gene in the species Homo sapiens

    Septin-1 is a protein that in humans is encoded by the SEPTIN1 gene. It was renamed from SEPT1 to avoid problems where Microsoft Excel would auto-correct

    SEPTIN1

    SEPTIN1

    SEPTIN1

  • Septum (cell biology)
  • New cell wall that forms between two daughter cells in cell division

    of microtubules (from the center to the outside of the cell). In yeast, septins form a ring structure, to which other proteins are recruited. In particular

    Septum (cell biology)

    Septum (cell biology)

    Septum_(cell_biology)

  • MARCH5
  • Protein-coding gene in the species Homo sapiens

    signal transduction, and cell cycle regulation. Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the

    MARCH5

    MARCH5

    MARCH5

  • Proto-Balto-Slavic language
  • Reconstructed proto-language

    *uš? (> Proto-Western-Baltic *us) *šéš (> PS *šȅstь) Seven (7) *septḿ̥ *septín Eight (8) *oḱtṓw *aśtṓ Nine (9) *h₁néwn̥ *néwin (> variant *dewin) Ten (10)

    Proto-Balto-Slavic language

    Proto-Balto-Slavic_language

  • RTKN
  • Protein-coding gene in the species Homo sapiens

    (October 2005). "Possible role of Rho/Rhotekin signaling in mammalian septin organization". Oncogene. 24 (47): 7064–7072. doi:10.1038/sj.onc.1208862

    RTKN

    RTKN

    RTKN

  • Nikolay Dokholyan
  • Russian-American Biophysicist, academic and researcher

    motility. Septin Engineering for Immunotherapy: His lab engineered optogenetic and structural variants of cytoskeletal septin proteins (such as Septin-7) to

    Nikolay Dokholyan

    Nikolay Dokholyan

    Nikolay_Dokholyan

  • Chromosome 4
  • Human chromosome

    protein SDA1 homolog SEC24B: Sec24 homolog B SEC24D: Sec24 homolog D SEPT11: Septin-11 SLC9B2: solute carrier family 9 member B2 SLC10A4: solute carrier family

    Chromosome 4

    Chromosome 4

    Chromosome_4

  • Actomyosin ring
  • Cellular formation during cytokinesis

    by abscission. In fungi, it forms at the mother-bud neck before mitosis. Septin is heavily involved in the formation of the fungal AMR. In most bacteria

    Actomyosin ring

    Actomyosin ring

    Actomyosin_ring

  • WD repeat containing planar cell polarity effector
  • Protein-coding gene in the species Homo sapiens

    critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome

    WD repeat containing planar cell polarity effector

    WD repeat containing planar cell polarity effector

    WD_repeat_containing_planar_cell_polarity_effector

  • Chromosome 22
  • Human chromosome

    machinery component 50 homolog SEPT3: encoding protein neuronal-specific septin-3 SEPT5 SHFM3P1: SOX10 SYNGR1: encoding protein synaptogyrin-1 TBC1D10A:

    Chromosome 22

    Chromosome 22

    Chromosome_22

  • Universalglot
  • Constructed language created in 1868

    not de bank/un banknot (a banknote). septin (week): Lundai, Mardai, Erdai, Jovdai, Vendai, Samdai, Diodai = un septin Li mens (months): Januar, Februar,

    Universalglot

    Universalglot

  • Epigenomics AG
  • 2008). "Sensitive Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay". PLOS ONE. 3 (11) e3759. Bibcode:2008PLoSO...3

    Epigenomics AG

    Epigenomics_AG

  • GTPase
  • Class of enzymes

    the AAA+ superclass. G protein-coupled receptors Growth factor receptor Septins Stouten, PF; Sander, C; Wittinghofer, A; Valencia, A (1993). "How does

    GTPase

    GTPase

    GTPase

  • EXOC4
  • Protein-coding gene in the species Homo sapiens

    interactions, and structures of the mammalian brain sec6/8 complex and septin filaments". Neuron. 20 (6): 1111–22. doi:10.1016/S0896-6273(00)80493-6.

    EXOC4

    EXOC4

    EXOC4

  • CDC42EP2
  • Protein-coding gene in humans

    Kinoshita M, Noda M, Haystead T, Macara IG (Oct 2001). "Borg proteins control septin organization and are negatively regulated by Cdc42". Nature Cell Biology

    CDC42EP2

    CDC42EP2

    CDC42EP2

  • Gaiti Hasan
  • Indian scientist (born 1956)

    May 2016). "Store-independent modulation of Ca2+ entry through Orai by Septin 7". Nature Communications. 7 11751. Bibcode:2016NatCo...711751D. doi:10

    Gaiti Hasan

    Gaiti_Hasan

  • CDC42EP3
  • Protein-coding gene in humans

    Joberty G, Perlungher RR, Sheffield PJ, et al. (2001). "Borg proteins control septin organization and are negatively regulated by Cdc42". Nat. Cell Biol. 3 (10):

    CDC42EP3

    CDC42EP3

    CDC42EP3

  • CDC42 effector protein 5
  • Protein-coding gene in humans

    (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided

    CDC42 effector protein 5

    CDC42 effector protein 5

    CDC42_effector_protein_5

  • KIF1A
  • Motor protein in humans

    also required for several microtubule associated proteins (MAPs), such as septin-9 and MAP9, to exert their effects on KIF1A. Additionally, the K-loop facilitates

    KIF1A

    KIF1A

    KIF1A

  • EXOC1
  • Protein-coding gene in the species Homo sapiens

    interactions, and structures of the mammalian brain sec6/8 complex and septin filaments". Neuron. 20 (6): 1111–22. doi:10.1016/S0896-6273(00)80493-6.

    EXOC1

    EXOC1

    EXOC1

  • Cytokinesis
  • Final stage of cell division

    contractile forces by rectifying thermal fluctuations. Another protein, septin, has also been speculated to serve as a structural scaffold on which the

    Cytokinesis

    Cytokinesis

    Cytokinesis

  • Proto-Baltic language
  • Ancestor of the Baltic languages

    Proto-Baltic might have retained the uninflected numeral forms of *su̯eš, *septin 'seven', *aštō 'eight', *neu̯in 'nine' as well. The reconstruction of Latvian

    Proto-Baltic language

    Proto-Baltic_language

  • MARCH2
  • Protein-coding gene in the species Homo sapiens

    function upon viral and bacterial infections. Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the

    MARCH2

    MARCH2

    MARCH2

  • Protein inhibitor of activated STAT
  • 2001). "An E3-like factor that promotes SUMO conjugation to the yeast septins". Cell. 106 (6): 735–44. doi:10.1016/s0092-8674(01)00491-3. PMID 11572779

    Protein inhibitor of activated STAT

    Protein inhibitor of activated STAT

    Protein_inhibitor_of_activated_STAT

  • EXOC5
  • Protein-coding gene in the species Homo sapiens

    interactions, and structures of the mammalian brain sec6/8 complex and septin filaments". Neuron. 20 (6): 1111–22. doi:10.1016/S0896-6273(00)80493-6.

    EXOC5

    EXOC5

    EXOC5

  • FAM107B
  • Protein-coding gene in the species Homo sapiens

    that of FAM107B: that of a human septin trimer in Homo sapiens and that of the 3rd HMG-box of mouse UBF1. The septin trimer is that of a Ras-like GTPase

    FAM107B

    FAM107B

    FAM107B

  • Super-resolution dipole orientation mapping
  • quantitative imaging of excitation polarized fluorescence reveals ordered septin dynamics in live yeast". Biophysical Journal. 101 (4): 985–994. Bibcode:2011BpJ

    Super-resolution dipole orientation mapping

    Super-resolution_dipole_orientation_mapping

  • Mac Con Midhe
  • Gaelic Irish family of poets

    MacNamee is now rare in Connacht, it may be assumed that survivors of the septin that province have become Conmee, which has been widely absorbed in the

    Mac Con Midhe

    Mac_Con_Midhe

  • Ordospora colligata
  • Intracellular parasite

    homology to genes of D. pulex and D. magna. These genes code for the protein septin 7, which is important for the endocytosis-based invasion process of a fungal

    Ordospora colligata

    Ordospora colligata

    Ordospora_colligata

  • Plant defensin
  • Host-defense peptide family in plants

    et al. (April 2012). "The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans". Molecular

    Plant defensin

    Plant defensin

    Plant_defensin

  • EXOC3
  • Protein-coding gene in the species Homo sapiens

    interactions, and structures of the mammalian brain sec6/8 complex and septin filaments". Neuron. 20 (6): 1111–22. doi:10.1016/S0896-6273(00)80493-6.

    EXOC3

    EXOC3

    EXOC3

  • Cyclin-dependent kinase 14
  • Enzyme found in humans

    1". Yang, Tao; Gao Yan-Kun; Chen Jiang-Ye (Jul 2002). "KIAA0202, a human septin family member, interacting with hPFTAIRE1". Sheng Wu Hua Xue Yu Sheng Wu

    Cyclin-dependent kinase 14

    Cyclin-dependent kinase 14

    Cyclin-dependent_kinase_14

  • STX4
  • Protein-coding gene in the species Homo sapiens

    Nurden P, Nurden A, Trimble WS, Ware J (Mar 2002). "A prototypic platelet septin and its participation in secretion". Proceedings of the National Academy

    STX4

    STX4

    STX4

  • MARCH6
  • Protein-coding gene in the species Homo sapiens

    that in humans is encoded by the MARCH6 gene. Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the

    MARCH6

    MARCH6

    MARCH6

  • Patrick Hogan (biologist)
  • Cellular & Molecular Biologist

    Patrick G (2013-07-11). "An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry". Nature. 499 (7457): 238–242

    Patrick Hogan (biologist)

    Patrick_Hogan_(biologist)

  • Mitosis inducer protein kinase cdr2
  • kinases, which prevent progression of mitosis if there is a problem with septin. The N-terminus contains a sequence characteristic of serine/threonine protein

    Mitosis inducer protein kinase cdr2

    Mitosis_inducer_protein_kinase_cdr2

  • EXOC8
  • Protein-coding gene in humans

    interactions, and structures of the mammalian brain sec6/8 complex and septin filaments". Neuron. 20 (6): 1111–22. doi:10.1016/S0896-6273(00)80493-6.

    EXOC8

    EXOC8

    EXOC8

  • Fluorescent tag
  • Biochemical identification method

    S. cerevisiae septins revealed with fluorescent microscopy utilizing fluorescent labeling

    Fluorescent tag

    Fluorescent tag

    Fluorescent_tag

  • Citron kinase
  • Enzyme found in humans

    impaired the accumulation of 3 key proteins: Rho, Anillin and septins (specifically septin 6 and 7) in the intercellular bridge in mid–late telophase, which

    Citron kinase

    Citron kinase

    Citron_kinase

  • Pom1
  • , and Gould, K.L. “The GIN4 family kinase, Cdr2p, acts independently of septins in fission yeast. The Journal of Cell Science 117, 5293-5302 (2004).

    Pom1

    Pom1

  • Cell mechanics
  • dyneins), intermediate filaments, other assemblies such as spectrins and septins. The active non-equilibrium and non-linear rheological properties of cellular

    Cell mechanics

    Cell_mechanics

  • MAPK6
  • Protein-coding gene in the species Homo sapiens

    heterodimerization activity MAP kinase activity Cellular component nucleoplasm septin cytoskeleton cytosol nucleus cytoplasm protein-containing complex Biological

    MAPK6

    MAPK6

    MAPK6

  • GP1BB
  • Protein-coding gene in the species Homo sapiens

    a separate gene (septin 5) located upstream of this gene. In the absence of polyadenylation from its own imperfect site, the septin 5 gene uses the consensus

    GP1BB

    GP1BB

    GP1BB

  • Nick Talbot
  • British molecular geneticist (born 1965)

    research group's recent discoveries on fungal morphogenetic proteins, called septins, being essential for the rice blast pathogen to cause disease. Talbot was

    Nick Talbot

    Nick Talbot

    Nick_Talbot

  • EXOC2
  • Protein-coding gene in the species Homo sapiens

    interactions, and structures of the mammalian brain sec6/8 complex and septin filaments". Neuron. 20 (6): 1111–22. doi:10.1016/S0896-6273(00)80493-6.

    EXOC2

    EXOC2

    EXOC2

  • SOCS7
  • Protein-coding gene in the species Homo sapiens

    PMC 1190369. PMID 16127460. Kremer BE, Adang LA, Macara IG (Sep 2007). "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation

    SOCS7

    SOCS7

    SOCS7

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