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RNA family
Small Cajal body specific RNA 16 (also known as SCARNA16 or ACA47) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation
Small Cajal body specific RNA 16
Small_Cajal_body_specific_RNA_16
Class of small RNA molecules
are referred to as small Cajal body-specific RNAs (scaRNAs). This is in contrast to the majority of C/D box or H/ACA box snoRNAs, which localise to the
Small_nucleolar_RNA
Family of large biological molecules
(January 2007). "Sno/scaRNAbase: a curated database for small nucleolar RNAs and cajal body-specific RNAs". Nucleic Acids Research. 35 (Database issue): D183–D187
RNA
for the different types of RNA are listed and explained. List of cis-regulatory RNA elements RNA: Types of RNA Non-coding RNA Gribaldo S, Brochier-Armanet
List_of_RNAs
Primary cell of the nervous system
Ramón y Cajal also postulated the Law of Dynamic Polarization, which states that a neuron receives signals at its dendrites and cell body and transmits
Neuron
Organelle in eukaryotic cells
RNA processing, specifically small nucleolar RNA (snoRNA) and small nuclear RNA (snRNA) maturation, and histone mRNA modification. Similar to Cajal bodies
Cell_nucleus
Protein-coding gene in humans
U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation
EFTUD2
Protein-coding gene in the species Homo sapiens
Factors localized to Cajal bodies with the help of WRAP53β includes the SMN protein, small Cajal body-specific scaRNAs and the enzyme telomerase. WRAP53β
WRAP53
Human chromosome
RNU4ATAC: RNA, U4atac small nuclear (U12-dependent splicing) RPL37A: encoding protein 60S ribosomal protein L37a SATB2: Homeobox 2 SCARNA5: Small Cajal body-specific
Chromosome_2
Protein in animal cells
Shpargel KB, Matera AG (October 2001). "Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein". Genes & Development. 15
Survival_of_motor_neuron
Use of non-coding RNA to treat disease
distinguishes lncRNA from small non-coding RNAs which encompasses microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar
NcRNA_therapy
snoRNA See small nucleolar RNA. snRNA See small nuclear RNA. soluble RNA (sRNA) See transfer RNA. somatic cell Any biological cell forming the body of
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
Glial cell located throughout the brain and spinal cord
Ramón y Cajal defined a "third element" (cell type) besides neurons and astrocytes. Pío del Río Hortega, a student of Santiago Ramón y Cajal, first called
Microglia
Conversion of a gene's sequence into a mature gene product or products
compartments called Cajal bodies. Their bases are methylated or pseudouridinilated by a group of small Cajal body-specific RNAs (scaRNAs), which are structurally
Gene_expression
Protein-coding gene in the species Homo sapiens
Morris GE (2007). "Absence of gemin5 from SMN complexes in nuclear Cajal bodies". BMC Cell Biol. 8: 28. doi:10.1186/1471-2121-8-28. PMC 1939999. PMID 17640370
Gem-associated_protein_5
Endogenous tag expressed in different cells along neurogenesis and differentiated cells
staining since it stains the cell body and the endoplasmic reticulum. In 1887, a Spanish scientist called Santiago Ramon y Cajal learned the staining technique
Neuronal_lineage_marker
Organ system within humans and other animals
tract. Exceptions are more primitive ones: sponges have small pores (ostia) throughout their body for digestion and a larger dorsal pore (osculum) for excretion
Gastrointestinal_tract
Aqueous phase rich in macromolecules
"Cajal Bodies, Nucleoli, and Speckles in the Xenopus Oocyte Nucleus Have a Low-Density, Sponge-like Structure". Molecular Biology of the Cell. 16 (1):
Coacervate
Protein-coding gene in the species Homo sapiens
snRNP-specific protein C". Nucleic Acids Research. 23 (23): 4864–71. doi:10.1093/nar/23.23.4864. PMC 307476. PMID 8532530. "Entrez Gene: SNRPC small nuclear
Small nuclear ribonucleoprotein polypeptide C
Small_nuclear_ribonucleoprotein_polypeptide_C
Protein-coding gene in the species Homo sapiens
PMID 15231748. Nesic D, Tanackovic G, Krämer A (September 2004). "A role for Cajal bodies in the final steps of U2 snRNP biogenesis". Journal of Cell Science.
SF3A2
Protein-coding gene in the species Homo sapiens
"Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies". The Journal of Cell Biology. 160 (4): 505–16. doi:10.1083/jcb.200210087
SART3
Class of membrane-less organelles within biological cells
biomolecular condensates. Perinuclear compartment Nucleolus Nuclear speckle Cajal body Paraspeckle Synaptonemal complex Other nuclear structures including heterochromatin
Biomolecular_condensate
Protein found in humans
plays a role in export of various RNAs including U snRNAs, rRNAs (as a part of ribosomal subunits), and some mRNAs. XPO1 is involved in various viral
XPO1
Human protein and coding gene
fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses". Cell. 112 (3): 317–27. doi:10
FMR1
Protein-coding gene in the species Homo sapiens
Query CC, Meier UT (2003). "Immunopurified small nucleolar ribonucleoprotein particles pseudouridylate rRNA independently of their association with phosphorylated
Nucleolar_phosphoprotein_p130
Protein-coding gene in the species Homo sapiens
binding of U2 snRNP to the pre-mRNA branch site. This gene encodes a small (~35 kDa) subunit that plays a critical role in RNA splicing by recognizing and
U2 small nuclear RNA auxiliary factor 1
U2_small_nuclear_RNA_auxiliary_factor_1
and asked him to withdraw his report. In 1888, in Spain, Santiago Ramón y Cajal, having used the Italian scientist Camillo Golgi's technique for staining
List_of_multiple_discoveries
Protein-coding gene in the species Homo sapiens
Neugebauer KM (Sep 2004). "Detection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transfer". The Journal of Cell Biology
LSM7
Protein-coding gene in humans
snRNA-associated Sm-like protein LSm10 is a protein that in humans is encoded by the LSM10 gene. LSM10 has been shown to interact with LSM3. U7 small nuclear
LSM10
Glycoprotein involved in neuronal migration
be specific monoclonal antibodies for reelin, and were termed CR-50 (Cajal–Retzius marker 50). They noted that CR-50 reacted specifically with Cajal–Retzius
Reelin
Neuron communication by electric impulses
tissue is made up of discrete cells, the Spanish physician Santiago Ramón y Cajal and his students used a stain developed by Camillo Golgi to reveal the myriad
Action_potential
Persistent strengthening of synapses based on recent patterns of activity
the absence of new neurons. The Spanish neuroanatomist Santiago Ramón y Cajal was among the first to suggest a mechanism of learning that did not require
Long-term_potentiation
Protein-coding gene in the species Homo sapiens
"Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins". RNA. 5 (12): 1597–604. doi:10.1017/S1355838299991288. PMC 1369881
NOP58
Protein-coding gene in the species Homo sapiens
Bertrand E, Tazi J, Bordonné R (2004). "Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival
TGS1
Structure in the midbrain
of the tectal system is to direct behavioral responses toward specific points in body-centered space. Each layer contains a topographic map of the surrounding
Superior_colliculus
Japanese stem cell researcher (born 1962)
formation, were used. However, now, non-integrating viruses, stabilised RNAs or proteins, or episomal plasmids (integration-free delivery mechanism) are
Shinya_Yamanaka
tolerance and developing the theory of clonal selection Santiago Ramón y Cajal (1852–1934): Spanish pathologist, histologist, neuroscientist; considered
List_of_agnostics
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