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SPECTRIN

  • Spectrin
  • Cytoskeletal protein

    Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane in many eukaryotic cells, including animal cells but not in

    Spectrin

    Spectrin

    Spectrin

  • Spectrin, alpha 1
  • Protein-coding gene in the species Homo sapiens

    Spectrin alpha chain, erythrocyte is a protein that in humans is encoded by the SPTA1 gene. Spectrin is an actin crosslinking and molecular scaffold protein

    Spectrin, alpha 1

    Spectrin, alpha 1

    Spectrin,_alpha_1

  • SPTAN1
  • Protein-coding gene in the species Homo sapiens

    Alpha II-spectrin, also known as Spectrin alpha chain, brain is a protein that in humans is encoded by the SPTAN1 gene. Alpha II-spectrin is expressed

    SPTAN1

    SPTAN1

    SPTAN1

  • Cell cortex
  • Layer on the inner face of a cell membrane

    protein spectrin may be present in the cortex. Spectrin helps to create a network by cross-linked actin filaments. The proportions of spectrin and actin

    Cell cortex

    Cell cortex

    Cell_cortex

  • Spectrin repeat
  • Protein family

    Spectrin repeats are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin, dystrophin and more recently

    Spectrin repeat

    Spectrin repeat

    Spectrin_repeat

  • Nesprin
  • Protein family

    Nesprins (nuclear envelope spectrin repeat proteins) are a family of proteins that are found primarily in the outer nuclear membrane, as well as other

    Nesprin

    Nesprin

  • Protein 4.1
  • Protein-coding gene in the species Homo sapiens

    stability and deformability by stabilizing spectrin-actin interaction. Protein 4.1 (80 kD) interacts with spectrin and short actin filaments to form the erythrocyte

    Protein 4.1

    Protein 4.1

    Protein_4.1

  • Cytoskeleton
  • Network of filamentous proteins that forms the internal framework of cells

    immobilizing the harmful microbes and preventing them from invading other cells. Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma

    Cytoskeleton

    Cytoskeleton

    Cytoskeleton

  • Actinin
  • Protein factor that regulates the length of R-actin

    horizontal axis. Alpha-actinin is a part of the spectrin superfamily. This superfamily is made of spectrin, dystrophin, and their homologous and isoforms

    Actinin

    Actinin

  • SPTBN5
  • Protein-coding gene in the species Homo sapiens

    Spectrin, beta, non-erythrocytic 5 also known as SPTBN5 is a protein that in humans is encoded by the SPTBN5 gene. SPTBN5 belongs to the spectrin family

    SPTBN5

    SPTBN5

    SPTBN5

  • Hereditary spherocytosis
  • Genetic disorder causing red blood cells to be spherical

    Alpha-1 refers the alpha-1 subunit of the spectrin protein. The Beta refers the beta subunit of the spectrin protein. These genetic mutations are acted

    Hereditary spherocytosis

    Hereditary spherocytosis

    Hereditary_spherocytosis

  • Diffuse axonal injury
  • Medical condition

    process called calpain-mediated spectrin proteolysis, or CMSP, begins to occur. Calpain breaks down a molecule called spectrin, which holds the membrane onto

    Diffuse axonal injury

    Diffuse axonal injury

    Diffuse_axonal_injury

  • Node of Ranvier
  • Gaps between myelin sheaths on the axon of a neuron

    expression of Na+ channels. Ankyrin has been found to be bounded to βIV spectrin, a spectrin isoform enriched at nodes of Ranvier and axon initial segments. The

    Node of Ranvier

    Node of Ranvier

    Node_of_Ranvier

  • SPTBN1
  • Protein-coding gene in the species Homo sapiens

    Spectrin beta chain, brain 1 is a protein that in humans is encoded by the SPTBN1 gene. Spectrin is an actin crosslinking and molecular scaffold protein

    SPTBN1

    SPTBN1

    SPTBN1

  • Ankyrin
  • Protein family

    membrane proteins to the spectrin-actin based membrane cytoskeleton. Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families

    Ankyrin

    Ankyrin

    Ankyrin

  • Nezha (disambiguation)
  • Topics referred to by the same term

    folk religion. Nezha or Ne Zha may also refer to: Calmodulin-regulated spectrin-associated protein 3, also sometimes known as Nezha Nezha (given name)

    Nezha (disambiguation)

    Nezha_(disambiguation)

  • SPTBN4
  • Protein-coding gene in the species Homo sapiens

    Spectrin, beta, non-erythrocytic 4, also known as SPTBN4, is a protein that in humans is encoded by the SPTBN4 gene. Spectrin is an actin crosslinking

    SPTBN4

    SPTBN4

    SPTBN4

  • Fluopicolide
  • Chemical compound

    precise mode of action is not known, but it is thought to act by affecting spectrin-like proteins in the cytoskeleton of oomycetes. This mode of action differs

    Fluopicolide

    Fluopicolide

    Fluopicolide

  • Hereditary elliptocytosis
  • Genetic haematological condition

    it is generally true that α-spectrin mutations result in an inability of α-spectrin to interact properly with β-spectrin to form a heterodimer. In contrast

    Hereditary elliptocytosis

    Hereditary elliptocytosis

    Hereditary_elliptocytosis

  • SPTB
  • Protein-coding gene in the species Homo sapiens

    Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene. GRCh38: Ensembl release 89: ENSG00000070182 – Ensembl, May 2017

    SPTB

    SPTB

    SPTB

  • Actin-binding protein
  • Class of proteins

    polymers, or both. Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin-binding calponin

    Actin-binding protein

    Actin-binding_protein

  • Calmodulin-regulated spectrin-associated CKK domain
  • Protein domain

    In molecular biology, the calmodulin-regulated spectrin-associated CKK domain (also known as the CKK domain) is a domain which occurs at the C-terminus

    Calmodulin-regulated spectrin-associated CKK domain

    Calmodulin-regulated spectrin-associated CKK domain

    Calmodulin-regulated_spectrin-associated_CKK_domain

  • Impala
  • Species of antelope found in Africa

    dorsalis) and the klipspringer (Oreotragus oreotragus). An rRNA and β-spectrin nuclear sequence analysis in 2003 also supported an association between

    Impala

    Impala

    Impala

  • CAMSAP2
  • Protein found in humans

    Calmodulin-regulated spectrin-associated protein family member 2 (CAMSAP2) is a protein in humans that is encoded by the CAMSAP2 gene. CAMSAP2 possesses

    CAMSAP2

    CAMSAP2

    CAMSAP2

  • Actin filament
  • Filament in the cytoplasm of eukaryotic cells

    embryonic kidney cells, neurons, and sperm cells. In red blood cells, a spectrin-actin hexagonal lattice is formed by interconnected short actin filaments

    Actin filament

    Actin filament

    Actin_filament

  • Calmodulin-regulated spectrin-associated protein 3
  • Microtubule minus-end binding human protein

    Calmodulin-regulated spectrin-associated protein family member 3 (CAMSAP3) is a human protein encoded by the gene CAMSAP3. The protein is commonly referred

    Calmodulin-regulated spectrin-associated protein 3

    Calmodulin-regulated spectrin-associated protein 3

    Calmodulin-regulated_spectrin-associated_protein_3

  • SPTBN2
  • Protein-coding gene in the species Homo sapiens

    Spectrin beta chain, brain 2 is a protein that in humans is encoded by the SPTBN2 gene. Mutations in this gene is associated with Spinocerebellar ataxia

    SPTBN2

    SPTBN2

    SPTBN2

  • Hereditary pyropoikilocytosis
  • Medical condition

    associated with a defect of the erythrocyte membrane protein spectrin and with spectrin deficiency. It was characterized in 1975. It is considered a severe

    Hereditary pyropoikilocytosis

    Hereditary pyropoikilocytosis

    Hereditary_pyropoikilocytosis

  • CAMSAP1
  • Microtubule minus-end binding human protein

    Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) is a human protein encoded by the gene CAMSAP1. Like other CAMSAP-family proteins, it is a

    CAMSAP1

    CAMSAP1

    CAMSAP1

  • SYNE2
  • Protein-coding gene in the species Homo sapiens

    the nuclear envelope (NE) spectrin-repeat (nesprin) family. Nesprins are modular proteins with a central extended spectrin-repeat (SR) rod domain and

    SYNE2

    SYNE2

    SYNE2

  • Spectrin repeat containing nuclear envelope family member 3
  • Protein-coding gene in the species Homo sapiens

    Spectrin repeat containing nuclear envelope family member 3, or Nesprin-3, is a Nesprin-family protein that in humans is encoded by the SYNE3 gene. Nesprin-3

    Spectrin repeat containing nuclear envelope family member 3

    Spectrin repeat containing nuclear envelope family member 3

    Spectrin_repeat_containing_nuclear_envelope_family_member_3

  • Ground substance
  • Extracellular non-fibrous substance

    during staining in the preparation process. Link proteins such as vinculin, spectrin and actomyosin stabilize the proteoglycans and organize elastic fibers

    Ground substance

    Ground_substance

  • List of MeSH codes (D12.776)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D12.776)

    List_of_MeSH_codes_(D12.776)

  • Pleckstrin homology domain
  • Clinical Significance

    Caenorhabditis elegans kinesin-like protein unc-104 (see InterPro: IPR001752), spectrin beta-chain, syntrophin (2 PH domains), and S. cerevisiae nuclear migration

    Pleckstrin homology domain

    Pleckstrin homology domain

    Pleckstrin_homology_domain

  • Terminal web
  • Structure on the surface of epithelial cells

    microvilli. It is composed primarily of actin filaments stabilized by spectrin, which also anchors the terminal web to the apical cell membrane. The presence

    Terminal web

    Terminal_web

  • Neural plate
  • Structure in an embryo which will become the nervous system

    6a7022.2006. PMID 16899759. Sadler, T.W. (1986). "A potential role for spectrin during neurulation". J. Embryol. 94 (1): 73–82. Retrieved 27 April 2013

    Neural plate

    Neural plate

    Neural_plate

  • Filaggrin
  • Protein found in Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Filaggrin

    Filaggrin

    Filaggrin

  • Brain-derived neurotrophic factor
  • Protein found in humans

    the growing ends of actin filaments and promote their association with spectrin, another cytoskeletal protein, to create stable and integrated cytoskeletal

    Brain-derived neurotrophic factor

    Brain-derived neurotrophic factor

    Brain-derived_neurotrophic_factor

  • Fusome
  • germ cell development. Cytoskeleton components, such as alpha and beta spectrins, hu-li tai shao (hts), and ankyrin were the first proteins identified

    Fusome

    Fusome

    Fusome

  • Peter Agre
  • American physician and academic (born 1949)

    Department at Johns Hopkins where he studied red cell membranes and identified spectrin deficiency as a common cause of hereditary spherocytosis, a hemolytic anemia

    Peter Agre

    Peter Agre

    Peter_Agre

  • Alpha-actinin-4
  • Protein-coding gene in the species Homo sapiens

    belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins

    Alpha-actinin-4

    Alpha-actinin-4

    Alpha-actinin-4

  • Activity-regulated cytoskeleton-associated protein
  • Protein-coding gene in the species Homo sapiens

    is conserved across vertebrate species and has low sequence homology to spectrin, a cytoskeletal protein involved in forming the actin cellular cortex.

    Activity-regulated cytoskeleton-associated protein

    Activity-regulated cytoskeleton-associated protein

    Activity-regulated_cytoskeleton-associated_protein

  • ADD2
  • Protein-coding gene in the species Homo sapiens

    to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial

    ADD2

    ADD2

    ADD2

  • Dystrophin
  • Rod-shaped cytoplasmic protein

    "The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families". Journal of Cell Science. 115 (Pt 22): 4215–25. doi:10

    Dystrophin

    Dystrophin

    Dystrophin

  • Desmoplakin
  • Protein found in humans

    further sub divided into a region called the "Plakin domain" made up of six spectrin repeat domains separated by SH3 domain. A crystal structure of part of

    Desmoplakin

    Desmoplakin

    Desmoplakin

  • Kinesin
  • Eukaryotic motor protein

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Kinesin

    Kinesin

    Kinesin

  • Keratin
  • Structural fibrous protein

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Keratin

    Keratin

    Keratin

  • CSRP3
  • Protein-coding gene in humans

    costameres, where it binds to zyxin, integrin linked kinase (ILK) and beta1-spectrin; intercalated discs, where it associates with the nebulin-related anchoring

    CSRP3

    CSRP3

    CSRP3

  • Cell membrane
  • Biological membrane that separates the interior of a cell from its outside environment

    packed lipid bilayer that works closely with the cytoskeleton components spectrin and actin. These cytoskeleton components are able to bind to and interact

    Cell membrane

    Cell membrane

    Cell_membrane

  • Vimentin
  • Type III intermediate filament protein

    microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin". The Journal of Biological Chemistry. 262 (3): 1320–1325. doi:10

    Vimentin

    Vimentin

    Vimentin

  • PDE6G
  • Protein-coding gene in the species Homo sapiens

    expression data Gene ontology Molecular function enzyme inhibitor activity spectrin binding cGMP binding protein binding 3',5'-cyclic-GMP phosphodiesterase

    PDE6G

    PDE6G

    PDE6G

  • Enaptin
  • Protein-coding gene

    that in humans that is encoded by the SYNE1 gene. This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and

    Enaptin

    Enaptin

    Enaptin

  • Microvillus
  • Microscopic protrusion of a cell membrane that increases surface area substantially

    in the terminal web composed of a complicated set of proteins including spectrin and myosin II. The space between microvilli at a cell's surface is called

    Microvillus

    Microvillus

    Microvillus

  • Actin
  • Family of proteins that form microfilaments

    rings is found in axons. In this structure, the actin rings, together with spectrin tetramers that link the neighboring actin rings, form a cohesive cytoskeleton

    Actin

    Actin

    Actin

  • Calpain-1 catalytic subunit
  • Protein found in humans

    SB, Zhang Z, Morrow JS (1997). "Site-directed mutagenesis of alpha II spectrin at codon 1175 modulates its mu-calpain susceptibility". Biochemistry. 36

    Calpain-1 catalytic subunit

    Calpain-1 catalytic subunit

    Calpain-1_catalytic_subunit

  • Peripheral membrane protein
  • Membrane proteins that adhere temporarily to membranes with which they are associated

    Archived from the original on 2007-09-29. Retrieved 2007-01-25. "Pfam entry Spectrin". Archived from the original on 2007-09-26. Retrieved 2007-01-25. Rochat

    Peripheral membrane protein

    Peripheral membrane protein

    Peripheral_membrane_protein

  • Microtubule-associated protein 2
  • Mammalian protein found in Homo sapiens

    (April 1991). "Interaction domains of neurofilament light chain and brain spectrin". Biochem. J. 275 (Pt 2): 521–7. doi:10.1042/bj2750521. PMC 1150082. PMID 1902666

    Microtubule-associated protein 2

    Microtubule-associated protein 2

    Microtubule-associated_protein_2

  • Glial fibrillary acidic protein
  • Type III intermediate filament protein

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Glial fibrillary acidic protein

    Glial fibrillary acidic protein

    Glial_fibrillary_acidic_protein

  • Cytokeratin
  • Keratin protein

    three components, have been probed to associate also with the ankyrin and spectrin complex protein network that underlies the cell membrane.[citation needed]

    Cytokeratin

    Cytokeratin

    Cytokeratin

  • Neurofilament light polypeptide
  • Protein-coding gene in the species Homo sapiens

    (April 1991). "Interaction domains of neurofilament light chain and brain spectrin". The Biochemical Journal. 275 (2): 521–527. doi:10.1042/bj2750521. PMC 1150082

    Neurofilament light polypeptide

    Neurofilament light polypeptide

    Neurofilament_light_polypeptide

  • Fluorescein isothiocyanate
  • Chemical compound

    in the erythrocyte membrane by the cytoskeletal network: dependence on spectrin association state". Biochemistry. 25 (20): 6133–6139. doi:10.1021/bi00368a045

    Fluorescein isothiocyanate

    Fluorescein isothiocyanate

    Fluorescein_isothiocyanate

  • Nuclear envelope
  • Nuclear membrane surrounding the nucleus in eukaryotic cells

    the endoplasmic reticulum. All four nesprin proteins (nuclear envelope spectrin repeat proteins) present in mammals are expressed in the outer nuclear

    Nuclear envelope

    Nuclear envelope

    Nuclear_envelope

  • Microtubule
  • Polymer of tubulin that forms part of the cytoskeleton

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Microtubule

    Microtubule

    Microtubule

  • Tubulin beta-3 chain
  • Microtubule element of the tubulin family

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Tubulin beta-3 chain

    Tubulin beta-3 chain

    Tubulin_beta-3_chain

  • Emery–Dreifuss muscular dystrophy
  • Medical condition

    {{cite book}}: |work= ignored (help), update 2011 "OMIM Entry – * 608441 – SPECTRIN REPEAT-CONTAINING NUCLEAR ENVELOPE PROTEIN 1; SYNE1". www.omim.org. Archived

    Emery–Dreifuss muscular dystrophy

    Emery–Dreifuss muscular dystrophy

    Emery–Dreifuss_muscular_dystrophy

  • PRKCQ
  • Protein-coding gene in the species Homo sapiens

    lymphoid cells where it negatively influence and delay the aggregation of spectrin in an early phase of apoptosis. PKC-θ has a role in the transduction of

    PRKCQ

    PRKCQ

    PRKCQ

  • Ankyrin-1
  • Protein-coding gene in the species Homo sapiens

    are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility

    Ankyrin-1

    Ankyrin-1

    Ankyrin-1

  • List of A1 genes, proteins or receptors
  • amyloid A1 Solute carrier family 35 (CMP-sialic acid transporter), member A1 Spectrin, alpha 1 Sperm protein associated with the nucleus, X-linked, family member

    List of A1 genes, proteins or receptors

    List_of_A1_genes,_proteins_or_receptors

  • Poisson–Boltzmann equation
  • Equation used for physiological interfaces, polymer science, and semiconductors

    bilayer of an erythrocyte. This takes into account both the glycocalyx and spectrin layers of the erythrocyte membrane. This information is useful for many

    Poisson–Boltzmann equation

    Poisson–Boltzmann_equation

  • List of MeSH codes (D12.776.543)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D12.776.543)

    List_of_MeSH_codes_(D12.776.543)

  • Titin
  • Largest known protein in human muscles

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Titin

    Titin

    Titin

  • Beta-actin
  • Protein-coding gene in the species Homo sapiens

    Tokito M, Stankewich MC, Morrow JS, Holzbaur EL (Sep 2001). "beta III spectrin binds to the Arp1 subunit of dynactin". The Journal of Biological Chemistry

    Beta-actin

    Beta-actin

    Beta-actin

  • Tropomyosin
  • Protein

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Tropomyosin

    Tropomyosin

    Tropomyosin

  • Myosin
  • Family of motor proteins

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Myosin

    Myosin

    Myosin

  • Gap-43 protein
  • Protein-coding gene in the species Homo sapiens

    number of different molecules, including PKC, PIP2, actin, calmodulin, spectrin, palmitate, synaptophysin, amyloid and tau protein, it may be useful to

    Gap-43 protein

    Gap-43 protein

    Gap-43_protein

  • Erythrocyte deformability
  • Ability of red blood cells to deform under stress without rupturing

    supports that aid resilience, which include the cytoskeleton: actin and spectrin that are held together by ankyrin. Shape change of erythrocytes under applied

    Erythrocyte deformability

    Erythrocyte_deformability

  • MYH1
  • Protein-coding gene in the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    MYH1

    MYH1

    MYH1

  • KRIT1
  • Gene of the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    KRIT1

    KRIT1

    KRIT1

  • Tonofibril
  • Protein cytoskeletal component

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Tonofibril

    Tonofibril

  • Keratin 12
  • Protein found in humans

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Keratin 12

    Keratin 12

    Keratin_12

  • Spherocytosis
  • Abnormal presence of spherical red blood cells in the blood

    or more of the proteins of the red blood cell cytoskeleton, including spectrin, ankyrin, Band 3, or Protein 4.2. Because the cell skeleton has a defect

    Spherocytosis

    Spherocytosis

    Spherocytosis

  • TUBA8
  • Protein-coding gene in the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    TUBA8

    TUBA8

    TUBA8

  • MYL2
  • Protein-coding gene in the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    MYL2

    MYL2

    MYL2

  • GRIA2
  • Mammalian protein found in Homo sapiens

    "Interaction of the C-terminal domain of delta glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells". Neuroscience Research

    GRIA2

    GRIA2

    GRIA2

  • PLEKHA7
  • Protein-coding gene in the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    PLEKHA7

    PLEKHA7

    PLEKHA7

  • Arp2/3 complex
  • Macromolecular complex

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Arp2/3 complex

    Arp2/3 complex

    Arp2/3_complex

  • Red blood cell
  • Oxygen-delivering blood cell and the most common type of blood cell

    interactions with skeletal proteins such as spectrin and protein 4.1R. Recent studies have shown that binding of spectrin to PS promotes membrane mechanical stability

    Red blood cell

    Red blood cell

    Red_blood_cell

  • RNA activation
  • Biological gene-regulation phenomenon

    infarction. and erectile dysfunction (ED). saRNA-mediated activation of βII spectrin alleviated ischemia/reperfusion (I/R)-induced cardiac contractile dysfunction

    RNA activation

    RNA_activation

  • Α-Catenin
  • Primary protein link between cadherins and the actin cytoskeleton

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Α-Catenin

    Α-Catenin

    Α-Catenin

  • Axolemma
  • Cell membrane of an axon

    of this structure is formed by hexagonal or pentagonal arrangement of spectrin on the inside of the cell membrane, as well as actin connected to the transmembrane

    Axolemma

    Axolemma

    Axolemma

  • LINC complex
  • filaments (through dynein and kinesin motors), intermediate filaments (through spectrin), centrosomes and cytoplasmic organelles. The number of SUN-domain and

    LINC complex

    LINC_complex

  • Dynactin
  • Motor protein

    vesicles (such as Golgi or late endosome) through its association with β-spectrin. The pointed end complex (PEC) has been shown to be involved in selective

    Dynactin

    Dynactin

    Dynactin

  • MYO9B
  • Protein-coding gene in the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    MYO9B

    MYO9B

    MYO9B

  • Keratin 20
  • Protein found in humans

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Keratin 20

    Keratin 20

    Keratin_20

  • ACTA2
  • Protein-coding gene in the species Homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    ACTA2

    ACTA2

    ACTA2

  • Alpha-actinin-1
  • Protein-coding gene in the species Homo sapiens

    belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins

    Alpha-actinin-1

    Alpha-actinin-1

    Alpha-actinin-1

  • KIF18B
  • Mammalian protein found in homo sapiens

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    KIF18B

    KIF18B

    KIF18B

  • Catenin
  • Type of protein

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Catenin

    Catenin

    Catenin

  • Lamin
  • Fibrous proteins

    catenin GAN Membrane Dystrophin Dystroglycan Utrophin Ankyrin ANK1 ANK2 ANK3 Spectrin SPTA1 SPTAN1 SPTB SPTBN1 SPTBN2 SPTBN4 SPTBN5 Other Plakins Corneodesmosin

    Lamin

    Lamin

    Lamin

  • PTPRN
  • Protein-coding gene in the species Homo sapiens

    Maksimova E, Stabach P, Hermel JM, et al. (November 2000). "betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the

    PTPRN

    PTPRN

    PTPRN

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Online names & meanings

  • Faqir
  • Boy/Male

    Indian

    Faqir

    Poor, Needy

  • Asuppim
  • Girl/Female

    Biblical

    Asuppim

    Gatherings.

  • Moris
  • Surname or Lastname

    English, Welsh, and Scottish

    Moris

    English, Welsh, and Scottish : variant of Morris.Dutch and North German : variant of Moritz.French : variant of Maurice.Latvian : nickname for a dark person, from Moris ‘Moor’, ‘Negro’. Compare Moore 2.Lithuanian : possibly a nickname from morỹs ‘lazy person’.

  • Rabah
  • Girl/Female

    Hebrew

    Rabah

    Fourth born.

  • Tardif
  • Surname or Lastname

    English and French (Channel Islands)

    Tardif

    English and French (Channel Islands) : nickname for a sluggish person, from Middle English, Old French tardif ‘slow’ (Late Latin tardivus, for classical Latin tardus).A Tardif from the Brittany region of France is documented in Quebec City in 1637.

  • Johnna
  • Girl/Female

    English American

    Johnna

    Modern feminine of John and Jon.

  • Aaryaa
  • Girl/Female

    Indian

    Aaryaa

    Goddess Parvati, Durga, A noble lady

  • Dimitrie
  • Boy/Male

    Australian, Greek, Romanian

    Dimitrie

    Follower of Demeter

  • Rithul
  • Boy/Male

    Hindu, Indian, Malayalam, Marathi, Tamil

    Rithul

    Truth Seeking

  • Worman
  • Surname or Lastname

    English

    Worman

    English : possibly a variant of Warman.

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