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Human salivary gland
The paired submandibular glands (historically known as submaxillary glands) are major salivary glands located beneath the floor of the mouth. In adult
Submandibular_gland
Duct in the salivary gland
from each bilateral submandibular gland and sublingual gland to the sublingual caruncle in the floor of the mouth. The submandibular duct arises from deep
Submandibular_duct
Major salivary glands in the mouth
sublingual gland is the smallest and most diffuse of the three major salivary glands of the oral cavity, with the other two being the submandibular and parotid
Sublingual_gland
Lymph nodes near the jaw
superficial to the submandibular salivary gland, and posterolateral to the anterior belly of either digastric muscle. One gland, the middle gland of Stahr, which
Submandibular_lymph_nodes
Parasympathetic nerve bundle in the lower jaw
ganglion). The submandibular ganglion is small and fusiform in shape. It is situated above the deep portion of the submandibular gland, on the hyoglossus
Submandibular_ganglion
Region of the neck
anterior part contains the submandibular gland, superficial to which is the anterior facial vein, while imbedded in the gland is the facial artery and its
Submandibular_triangle
Major salivary gland in many animals
glands; they are submandibular and sublingual glands. Sometimes accessory parotid glands are found close to the main parotid glands. The venom glands
Parotid_gland
Medical condition
salivary glands consist of the parotid, submandibular, and sublingual glands. The minor salivary glands consist of 800 to 1000 small mucus-secreting glands located
Salivary_gland_tumour
Medical condition
gland diseases (SGDs) are multiple and varied in cause. There are three paired major salivary glands in humans: the parotid glands, the submandibular
Salivary_gland_disease
Formation of stones in the salivary glands
gland, usually in the duct of the submandibular gland (also termed "Wharton's duct"). Less commonly the parotid gland or rarely the sublingual gland or
Sialolithiasis
Gland that secretes serous fluid
alpha-amylase. Serous glands are most common in the parotid gland and lacrimal gland but are also present in the submandibular gland and, to a far lesser
Serous_gland
Watery-saliva producing cells of the salivary glands
salivary glands and ~600-1000 smaller minor salivary glands. Serous acinar cells are primarily found in the parotid gland and the submandibular gland, while
Salivary_serous_cell
Fascial space of the head and neck
lateral pharyngeal space In health, the contents of the space are: the submandibular gland, which largely fills the space, branches of the facial and lingual
Submandibular_space
Gland that secretes substances onto an epithelial surface by way of a duct
parotid gland (saliva secretion 25%) is predominantly serous, the sublingual gland (saliva secretion 5%) mainly mucous gland, and the submandibular gland (saliva
Exocrine_gland
Exocrine glands that produce saliva through a system of ducts
paired major salivary glands (parotid, submandibular, and sublingual), as well as hundreds of minor salivary glands. Salivary glands can be classified as
Salivary_gland
the mandible below the mylohyoid line. It is the location for the submandibular gland. This article incorporates text in the public domain from the 20th
Submandibular_fovea
Inflammation of the salivary glands
inflammation of salivary glands, usually the major ones, the most common being the parotid gland, followed by submandibular and sublingual glands. It should not
Sialadenitis
Medical condition
pathogenesis of the Küttner tumor of the submandibular gland - Analysis of 349 cases with chronic sialadenitis of the submandibular (author's translation)]. HNO (in
IgG4-related_disease
Depression of the jawbone
as the depression is created by ectopic salivary gland tissue associated with the submandibular gland and does not represent a pathologic lesion as such
Stafne_defect
subplatysmal fat, the anterior bellies of the digastric muscles and the submandibular glands. These structures can contribute to central bulging or fullness beneath
Platysmaplasty
Type of animal organ
A gland is a cell or an organ in an animal's body that produces and secretes different substances that the organism needs, either into the bloodstream
Gland
Benign growth on the salivary gland
the submandibular gland, but is also known to occur in other major and minor salivary glands, including the parotid gland. Overall, salivary gland tumors
Chronic sclerosing sialadenitis
Chronic_sclerosing_sialadenitis
Protein that stimulates cell division and differentiation
submaxillary glands of mice and in human urine. EGF has since been found in many human tissues, including platelets, submandibular gland (submaxillary gland), and
Epidermal_growth_factor
Channel leading from a bodily gland or organ
They are found in the submandibular gland, sublingual duct, and the parotid gland, but are more developed in the parotid gland. They are not present in
Duct_(anatomy)
Cranial nerve VII, for the face and tasting
synapses with the submandibular ganglion. Postsynaptic fibers from the submandibular ganglion supply the sublingual and submandibular glands. Upon emerging
Facial_nerve
Mammalian protein found in humans
lumbar subsegment of spinal cord blood tibiofemoral joint gastrula submandibular gland calvaria spleen superior frontal gyrus More reference expression
CD33
Protein-coding gene in the species Homo sapiens
tibial arteries Top expressed in submandibular gland right kidney human kidney parotid gland left lobe of liver lacrimal gland primary oocyte choroid plexus
Alpha-aminoadipic semialdehyde synthase
Alpha-aminoadipic_semialdehyde_synthase
glands of the human body There are several specialized glands within the human integumentary system that are derived from apocrine or sebaceous gland
List of glands of the human body
List_of_glands_of_the_human_body
Fascial space of the head and neck
recognized, known as Bartholin's duct. the deep part of the submandibular gland and the submandibular duct (Wharton's duct) some extrinsic tongue muscle fibers
Sublingual_space
a half-moon (hence the name "demilune") on the mixed submandibular and sublingual salivary glands. Serous demilunes are the serous cells at the distal
Serous_demilune
Tendons Digestive Mouth Teeth Tongue Lips Salivary glands Parotid glands Submandibular glands Sublingual glands Pharynx Esophagus Stomach Small intestine Duodenum
List of organs of the human body
List_of_organs_of_the_human_body
Protein-coding gene in humans
anterior pituitary Top expressed in mesenteric lymph nodes thymus submandibular gland otolith organ utricle brown adipose tissue hand right kidney proximal
NEIL1
Protein found in humans
tibiofemoral joint atrioventricular valve right lung mucous cell of stomach submandibular gland More reference expression data BioGPS More reference expression data
Syntenin-1
Rare form of cancer
salivary gland tumor overall (after mucoepidermoid carcinoma and polymorphous adenocarcinoma). It represents 28% of malignant submandibular gland tumors
Adenoid_cystic_carcinoma
Mammalian protein found in humans
expressed in mesenteric lymph nodes spleen blood oocyte primary oocyte submandibular gland tibiofemoral joint secondary oocyte zygote Ileal epithelium More
CD20
Protein-coding gene in the species Homo sapiens
membrane of cochlear duct cochlea granulocyte submandibular gland parasympathetic nervous system thyroid gland pharynx tongue More reference expression data
TMPRSS3
Protein-coding gene in humans
urinary bladder lip corneal stroma saccule otic placode otic vesicle submandibular gland esophagus duodenum More reference expression data BioGPS More reference
CLDN4
Protein-coding gene in the species Homo sapiens
epithelium of urinary bladder decidua thymus seminal vesicula granulocyte submandibular gland mesenteric lymph nodes lumbar spinal ganglion islet of Langerhans
USP18
Nerve carrying taste sensations
and parasympathetic (secretomotor) innervation to the submandibular and sublingual salivary glands. Chorda tympani has a complex course from the brainstem
Chorda_tympani
Protein-coding gene in the species Homo sapiens
immunoglobulins, secretory component and J chain in the human minor salivary glands". Journal of Oral Pathology. 17 (8): 390–395. doi:10.1111/j.1600-0714.1988
J_chain
Protein-coding gene in the species Homo sapiens
lacrimal gland dentate gyrus of hippocampal formation granule cell primary motor cortex parotid gland zygote cerebellar cortex submandibular gland hippocampus
SIDT1
Digestive system in humans
jaw, the submandibular glands, these produce both serous fluid and mucus. The serous fluid is produced by serous glands in these salivary glands which also
Human_digestive_system
Protein-coding gene in the species Homo sapiens
of glomerular capsule muscle of thigh lactiferous gland lumbar spinal ganglion submandibular gland More reference expression data BioGPS More reference
STC2
Protein-coding gene in the species Homo sapiens
aorta deep cerebellar nuclei ascending aorta motor neuron amygdala submandibular gland More reference expression data BioGPS More reference expression data
Plakophilin-4
Protein-coding gene in the species Homo sapiens
vestibular membrane of cochlear duct spleen triceps brachii muscle submandibular gland More reference expression data BioGPS More reference expression data
FCN1
Bodily fluid secreted by salivary glands
humans, when not stimulated, the submandibular gland contributes around 65 to 75% of secretions, while the parotid gland secretes about 20 to 25%; small
Saliva
Microtubule minus-end binding human protein
of thyroid gland salivary gland minor salivary glands Top expressed in secondary oocyte lip primary oocyte submandibular gland lacrimal gland zygote epiblast
Calmodulin-regulated spectrin-associated protein 3
Calmodulin-regulated_spectrin-associated_protein_3
Autoimmune disease
reduced production of saliva from the salivary glands (parotid gland, submandibular gland, and sublingual gland). In unstimulated whole saliva flow collection
Sjögren's_disease
Mammalian protein found in Homo sapiens
mesenteric lymph nodes molar left colon seminal vesicula tail of embryo submandibular gland temporal muscle Ileal epithelium tibiofemoral joint More reference
B-cell_linker
Protein-coding gene in the species Homo sapiens
of liver blood tibiofemoral joint human fetus cervix granulocyte submandibular gland bone marrow More reference expression data BioGPS n/a Gene ontology
Glutathione_peroxidase_1
Protein-coding gene in the species Homo sapiens
brachii Top expressed in muscle of thigh lacrimal gland stroma of bone marrow submandibular gland dorsomedial hypothalamic nucleus digastric muscle transitional
VAPB
Protein-coding gene in the species Homo sapiens
Top expressed in body of femur blastocyst cochlea submandibular gland adrenal gland pituitary gland lens lip islet of Langerhans respiratory system More
Dendrocyte expressed seven transmembrane protein
Dendrocyte_expressed_seven_transmembrane_protein
Protein-coding gene in humans
ankle joint Ileal epithelium morula gastrula intercostal muscle submandibular gland More reference expression data BioGPS More reference expression data
PLA2G2A
Protein-coding gene in the species Homo sapiens
fetal liver hematopoietic progenitor cell conjunctival fornix blood submandibular gland left colon facial motor nucleus tibiofemoral joint superior cervical
CMAS_(gene)
Protein-coding gene in the species Homo sapiens
in lacrimal gland parotid gland internal carotid artery external carotid artery migratory enteric neural crest cell submandibular gland calvaria seminal
ALDH18A1
Digestive organ
from the mouse submandibular gland, but since then found in many human tissues including the submandibular gland, and the parotid gland. Salivary EGF,
Stomach
Lectin molecule
lymph nodes blood tibiofemoral joint subcutaneous adipose tissue submandibular gland granulocyte calvaria morula tunica adventitia of aorta More reference
CD22
Protein-coding gene in the species Homo sapiens
Top expressed in tail of embryo Region II of hippocampus proper submandibular gland supramammillary nucleus medial amygdaloid nucleus CA3 field central
GZMK
Protein-coding gene in the species Homo sapiens
right hemisphere of cerebellum Top expressed in parotid gland lacrimal gland submandibular gland right kidney vestibular membrane of cochlear duct human
Deoxyribonuclease_I
Enzyme found in humans
"Immunoelectron microscopy of carbonic anhydrase isozyme VI in human submandibular gland: comparison with isozymes I and II". The Journal of Histochemistry
Carbonic_anhydrase_6
Protein-coding gene in the species Homo sapiens
oocyte gastrula decidua seminal vesicula lacrimal gland submandibular gland adrenal gland zygote parotid gland More reference expression data BioGPS More reference
ERN1
Mammalian protein found in humans
lymphatic vessel Ileal epithelium cervix right lung lobe left colon submandibular gland More reference expression data BioGPS More reference expression data
CD14
Abnormal passageway between salivary glands or ducts
fistulae are almost always related to the parotid gland or duct, although the submandibular gland is rarely the origin. The fistula can communicate with
Salivary_gland_fistula
Protein-coding gene in humans
bone marrow tibiofemoral joint spermatid embryo spleen Paneth cell submandibular gland seminiferous tubule blood More reference expression data BioGPS More
CLEC4A
Protein-coding gene in humans
spleen blood subcutaneous adipose tissue embryo white adipose tissue submandibular gland bone marrow embryo granulocyte More reference expression data BioGPS
FCMR
Protein-coding gene in the species Homo sapiens
adrenal gland left adrenal cortex Top expressed in submandibular gland lacrimal gland morula parotid gland spermatocyte esophagus blastocyst embryo seminal
Histo-blood group ABO system transferase
Histo-blood_group_ABO_system_transferase
Protein-coding gene in the species Homo sapiens
granulocyte blood spleen mesenteric lymph nodes thymus tibiofemoral joint submandibular gland fetal liver hematopoietic progenitor cell blastocyst More reference
INPP5D
Protein-coding gene in the species Homo sapiens
eminence gonad glomerulus Top expressed in parotid gland lacrimal gland left colon submandibular gland esophagus Epithelium of choroid plexus pyloric antrum
Gamma-glutamyl_hydrolase
Protein-coding gene in the species Homo sapiens
lymph nodes gastrula liver seminiferous tubule left lobe of liver submandibular gland sciatic nerve More reference expression data BioGPS More reference
MSR1
Protein-coding gene in the species Homo sapiens
gland Top expressed in lacrimal gland muscle of thigh saccule parotid gland yolk sac otic vesicle submandibular gland otic placode extensor digitorum
BCKDK
Protein found in humans
expressed in parotid gland submandibular gland left lung lobe left colon conjunctival fornix epithelium of small intestine lacrimal gland seminal vesicula
Erbin_(protein)
Protein-coding gene in the species Homo sapiens
coronary artery Top expressed in mesenteric lymph nodes spleen thymus submandibular gland carotid body right lung lip white adipose tissue right lung lobe
HLA-DRB1
Protein-coding gene in the species Homo sapiens
secondary oocyte primary oocyte lumbar subsegment of spinal cord embryo submandibular gland temporal muscle More reference expression data BioGPS n/a Gene ontology
HSF5
Mammalian protein found in humans
granulocyte spleen thymus tibiofemoral joint stroma of bone marrow submandibular gland blood right lung Paneth cell mesenteric lymph nodes More reference
PTPRC
Protein-coding gene in humans
small intestine duodenum Paneth cell parotid gland jejunum lacrimal gland left lobe of liver submandibular gland More reference expression data BioGPS More
Polymeric immunoglobulin receptor
Polymeric_immunoglobulin_receptor
Blood vessel
four large vessels, which supply the submandibular gland, some being prolonged to the neighboring muscles, lymph glands, and integument. This article incorporates
Glandular branches of facial artery
Glandular_branches_of_facial_artery
Division of the autonomic nervous system
controls secretion of the sublingual and submandibular salivary glands, the lacrimal gland, and the glands associated with the nasal cavity. The preganglionic
Parasympathetic nervous system
Parasympathetic_nervous_system
Protein-coding gene in the species Homo sapiens
pyloric antrum lacrimal gland epithelium of stomach mucous cell of stomach salivary gland submandibular gland parotid gland iris decidua Ileal epithelium
Melanophilin
Protein-coding gene in the species Homo sapiens
mesenteric lymph nodes spleen blood subcutaneous adipose tissue submandibular gland primitive streak thymus embryo granulocyte bone marrow More reference
BTLA
Protein-coding gene in the species Homo sapiens
Nagashunmugam T, Malamud D, Davis C, Abrams WR, Friedman HM (Dec 1998). "Human submandibular saliva inhibits human immunodeficiency virus type 1 infection by displacing
SLPI
Protein-coding gene in the species Homo sapiens
minor salivary glands right lobe of thyroid gland mucosa of ileum Top expressed in lacrimal gland neural layer of retina submandibular gland granulocyte
OS9_(gene)
Mammalian protein found in Homo sapiens
apocrine glands in the axilla, vulva, eyelid and ear canal, serous cells of the submandibular salivary gland, serous cells of the submucosal glands of the
Prolactin-induced_protein
Protein-coding gene in the species Homo sapiens
proximal tubule olfactory epithelium primitive streak lactiferous gland submandibular gland calvaria More reference expression data BioGPS n/a Orthologs Databases
MFSD1
Enzyme found in humans
adrenal cortex tibia left adrenal gland body of pancreas left adrenal cortex Top expressed in morula submandibular gland urethra endocardial cushion medullary
Tryptophan–tRNA ligase, mitochondrial
Tryptophan–tRNA_ligase,_mitochondrial
Protein-coding gene in the species Homo sapiens
glands Top expressed in granulocyte stroma of bone marrow mesenteric lymph nodes spleen tibiofemoral joint calvaria ankle joint ankle submandibular gland
UNC93B1
Protein-coding gene in the species Homo sapiens
gland Top expressed in submandibular gland parotid gland corneal stroma transitional epithelium of urinary bladder lacrimal gland lactiferous gland epithelium
Placenta expressed transcript 1
Placenta_expressed_transcript_1
Protein-coding gene in the species Homo sapiens
transitional epithelium of urinary bladder left colon submandibular gland decidua seminal vesicula lacrimal gland More reference expression data BioGPS n/a Gene
ANO1
Mammalian protein found in humans
lumbar subsegment of spinal cord urethra right lung right lung lobe submandibular gland left lung lobe respiratory epithelium More reference expression data
Wilson_disease_protein
Protein-coding gene in the species Homo sapiens
nigra submandibular gland medial dorsal nucleus anterior amygdaloid area cerebellar vermis medial geniculate nucleus lobe of cerebellum parotid gland More
G protein-coupled receptor kinase 3
G_protein-coupled_receptor_kinase_3
Protein-coding gene in humans
epithelium of urinary bladder vestibular sensory epithelium utricle submandibular gland interventricular septum myocardium of ventricle cardiac muscle tissue
S100A1
Human nerve relaying sense to the tongue
deep part of the submandibular gland; it finally runs from laterally to medially inferiorly crossing the duct of the submandibular gland, and along the
Lingual_nerve
Mammalian protein found in Homo sapiens
muscle canal of the cervix nipple glutes Top expressed in right lung submandibular gland right lung lobe masseter muscle left lung muscle of thigh brown adipose
TXNIP
Excretory duct of the sublingual gland
the sublingual gland are from eight to twenty in number. Of the smaller sublingual ducts (ducts of Rivinus), some join the submandibular duct; others open
Major_sublingual_duct
Cell-surface glycoprotein
expressed in molar granulocyte calvaria dermis submandibular gland epithelium of lens tibiofemoral joint parotid gland endothelial cell of lymphatic vessel body
CD44
Human enzyme
proximal tubule hippocampus proper primary visual cortex CA3 field submandibular gland islet of Langerhans More reference expression data BioGPS n/a Gene
Klotho_(biology)
Protein-coding gene in the species Homo sapiens
primary oocyte fossa Paneth cell hair follicle secondary oocyte submandibular gland primitive streak More reference expression data BioGPS n/a Gene ontology
PTPN2
Mammalian protein found in humans
and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women. PSA is produced for the ejaculate, where it liquefies
Prostate-specific_antigen
Mammalian protein found in humans
mesenteric lymph nodes spleen decidua tibiofemoral joint body of femur submandibular gland More reference expression data BioGPS n/a Gene ontology Molecular
CD43
Anatomical structure in the human neck
and muscles of facial expression. It also contains the submandibular and parotid salivary gland as well as the muscles of mastication (the masseter, pterygoid
Deep_cervical_fascia
Protein-coding gene in the species Homo sapiens
embryo vastus lateralis muscle central gray substance of midbrain submandibular gland skin of abdomen gastrula More reference expression data BioGPS n/a
ENTH domain-containing protein 1
ENTH_domain-containing_protein_1
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SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
SUBMANDIBULAR GLAND
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