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Canada-based charity
Transforming Cleft is a Canadian-based charity that provides comprehensive cleft care for children born with cleft lip and palate. Jackie Elton, a UK-based
Transforming_Cleft
This is a list of cleft lip and palate organisations around the world. Transforming Cleft AboutFace Smile Angel Foundation Cleft Lip and Palate Association
List of cleft lip and palate organisations
List_of_cleft_lip_and_palate_organisations
Protein-coding gene in the species Homo sapiens
PMID 16549496. "Entrez Gene: TGFB3 transforming growth factor, beta 3". Herpin A, Lelong C, Favrel P (May 2004). "Transforming growth factor-beta-related proteins:
Transforming growth factor, beta 3
Transforming_growth_factor,_beta_3
Malformation of the face
facial cleft is an opening or gap in the face, or a malformation of a part of the face. Facial clefts is a collective term for all sorts of clefts. All
Craniofacial_cleft
Solid part of maxilla
possible mutations found in the transforming growth factor-alpha gene (TGFA) that could lead to the development of a cleft palate. Even though several risk
Hard_palate
Children's charity for cleft defects
for children with cleft lips and palates. Headquartered in New York City and founded in 1999, Smile Train provides free corrective cleft surgery in 87 countries
Smile_Train
Protein
Medicine. "Entrez Gene: TGFA transforming growth factor alpha". Ojeda SR, Ma YJ, Rage F (September 1997). "The transforming growth factor alpha gene family
TGF_alpha
American dancer, choreographer and singer (born 1974)
Indonesian, and Chinese descent.[failed verification] She was born with a cleft lip and cleft palate. She was raised in Encino, California. Both parents were dancers;
Carmit_Bachar
Supernatural entity in Olmec mythology
is characterized by almond-shaped eyes, a downturned open mouth, and a cleft head. It appears widely in the Olmec archaeological record, and in many
Werejaguar
Medical condition
split uvula, and aneurysms at the aortic root. Other features may include cleft palate and a blue/gray appearance of the white of the eyes. Cardiac defects
Loeys–Dietz_syndrome
U.S.-based nonprofit organization
in 2004 in San Francisco. They provide free surgical repairs for cleft lip and cleft palate, with missions mostly in the continents of Asia and Africa
Alliance_for_Smiles
Fictional characters
Sometimes, Timmy joins him in his comic book adventures as his sidekick "Cleft the Boy Chin Wonder," and at other times, the Chin comes to the real world
List of The Fairly OddParents characters
List_of_The_Fairly_OddParents_characters
Long, narrow crack opening on a planetary surface
of Earth. The term is derived from the Latin word fissura, which means 'cleft' or 'crack'. Fissures emerge in Earth's crust, on ice sheets and glaciers
Fissure
Charity in UK
adults in Pakistan. The OPSA team operate on facial abnormalities including cleft lip and palate. OPSA was founded in 1998 by Nick Hart who, after travelling
Overseas Plastic Surgery Appeal
Overseas_Plastic_Surgery_Appeal
American singer and songwriter (1958–2009)
autobiography and a 1993 interview having only two rhinoplasty surgeries and a cleft chin surgery. He mentioned losing weight in the early 1980s because of his
Michael_Jackson
Dragon Gate in Chinese mythology
the border of Shanxi and Shaanxi where the Yellow River flows through a cleft in the Longmen mountains, supposedly made by Yu the Great, who cut through
Dragon_Gate_(mythology)
Primary cell of the nervous system
releasing their contents into the synaptic cleft. The neurotransmitters diffuse across the synaptic cleft and activate receptors on the postsynaptic neuron
Neuron
Interpretation of sensory information
amphetamine, which increases concentrations of dopamine at the synaptic cleft advances the start of responding during interval timing, whereas antagonists
Perception
American actor (born 1980)
continued to raise money for Operation Smile to help children with cleft lip and cleft palate receive surgery they need. In 2020, the Chuck cast performed
Zachary_Levi
West Germanic language
construction, "the girl was stung by the bee". Another way is through a cleft sentence where the main clause is demoted to be a complement clause of a
English_language
Roman goddess of wisdom
relieve the pain, Vulcan used a hammer to split Jupiter's head and, from the cleft, Minerva emerged, as a grown adult and in full battle armour.[citation needed]
Minerva
American actress and producer (born 1977)
around a bone structure that has a touch of the masculine, right down to the cleft in her chin." She was named the sexiest vegetarian actress in a poll conducted
Jessica_Chastain
"Skrep", which at a single blow of the smiter struck straight through and cleft asunder any obstacle whatsoever; nor would aught be hard enough to check
Weapons_of_Norse_mythology
Mountain in British Columbia, Canada
traditions say it is a longhouse transformed to stone by Xáays, as the Transformer Brothers are known in this language. The great cleft in the mountain's cliff-face
Stawamus_Chief
painting Chromosome region p Chromosome region q Classical genetics Cleft lip Cleft palate Clinical geneticist Clone (genetics) Clone bank Cloned DNA Cloning
Index_of_genetics_articles
2005 video game
formerly been a settlement. The only point of entry to the region is a small cleft in the mountains to the north that leads to a massive stone bridge. This
Shadow_of_the_Colossus
Greek goddess and mother of Apollo and Artemis
monsters that came across Leto was the dragon Python, which lived in a cleft of the mother-rock beneath Delphi and beside the Castalian Spring. Once
Leto
God of the underworld in Greek mythology
chthonic sacrifices including those to propitiate Hades dripped into a pit or cleft in the ground. The person who offered the sacrifice had to avert his face
Hades
Miracle attributed to Muhammad
that perhaps all three are applicable to the verse: Moon once appeared cleft asunder at the time of Muhammad to convince the unbelievers. It will split
Splitting_of_the_Moon
Medical history of American celebrity
had surgery on his nose, while at other times saying that he also had a cleft created in his chin. Jackson attributed the changes in the structure of
Health and appearance of Michael Jackson
Health_and_appearance_of_Michael_Jackson
Autoimmune disease
to any dysfunction at checkpoints of autoimmune B-cell activation to transform into malignancy. A study's findings concluded that continuous stimulation
Sjögren's_disease
1819 short story by Washington Irving
Dutch clothing and carrying a keg. Rip helps the man carry his burden to a cleft in the rocks from which thunderous noises are emanating; the source proves
Rip_Van_Winkle
Inflammatory disease involving a buildup of lesions in the walls of arteries
cells), which form areas of cholesterol crystals with empty, needle-like clefts. At the periphery of the plaque are younger "foamy" cells and capillaries
Atherosclerosis
Greek goddess of spring and the queen of the underworld
Hymn says, in a field when Hades came to abduct her, bursting through a cleft in the earth. In another version of the myth, Persephone had her own personal
Persephone
Greek and Roman mythological creature
cults of individual nymphs venerated by country people in the springs and clefts of Latium. Among the Roman literate class, their sphere of influence was
Nymph
Chemical herbicide and defoliant
was used have been affected and have multiple health problems, including cleft palate, mental disabilities, hernias, and extra fingers and toes. In the
Agent_Orange
2017 novel by Min Jin Lee
little more money. They have three sons, but only one, Hoonie, who has a cleft lip and club foot, survives to adulthood. Because of his deformities, Hoonie
Pachinko_(novel)
Wood with naturally occurring diamond-shaped patterns
not move back very much each year, then the diamonds will be deep bowl or cleft-shaped. These stems will be able to survive longer than the ones with flat
Diamond_willow
2021 novel by Anthony Doerr
Cuckoo Land and keeps it with her. Meanwhile, Omeir is a boy born with a cleft lip. He grows up in a remote cottage, where his grandfather teaches him
Cloud_Cuckoo_Land_(novel)
General cell type
proliferation and differentiation can also contribute to deformities such as cleft lips and Gorlin syndrome. In the respiratory tract, basal cells function
Basal_cell
Mountain in the Swiss and Italian Alps
but at a point not very far below the summit, they were stopped by a deep cleft that defied their utmost efforts. The Matterhorn remained unclimbed. Whymper
Matterhorn
Exocrine gland in humans and other mammals
other paracrine growth factors such as epidermal growth factor (EGF), transforming growth factor beta (TGF-β), amphiregulin, fibroblast growth factor (FGF)
Mammary_gland
Family of carnivoran mammals
is alluded to in a valley in Israel known as Shaqq-ud-Diba` (meaning "cleft of the hyenas") and Wadi-Abu-Diba` (meaning "valley of the hyenas"). Both
Hyena
Drug mixture used mainly to treat ADHD and narcolepsy
(primarily NE and DA) on the synaptic cleft. ... LDX can also promote the increase of DA in the synaptic cleft by activating protein TAAR1, which produces
Adderall
Central nervous system stimulant
(primarily NE and DA) on the synaptic cleft. ... LDX can also promote the increase of DA in the synaptic cleft by activating protein TAAR1, which produces
Amphetamine
First part of Dante Alighieri's Divine Comedy
Muhammad's son-in-law, Ali, for schism between Sunni and Shiite: his face is cleft from top to bottom. Muhammad tells Dante to warn the schismatic and heretic
Inferno_(Dante)
the disease formerly named CATCH22 for "cardiac anomaly, T-cell deficit, clefting and hypocalcaemia for chromosome 22q11.2 microdeletions". This name was
List of unusual biological names
List_of_unusual_biological_names
Sacred site and oracle of Ancient Greece
at the site flowed toward the temple but disappeared beneath, creating a cleft which emitted chemical vapors that purportedly caused the oracle at Delphi
Delphi
Attitudes and behaviors towards sex in ancient Rome
leaving it standing, in such a way that the boy can be passed through the cleft. Then join the sapling together again and seal it with cow manure and other
Sexuality_in_ancient_Rome
Tropane alkaloid and stimulant drug
Some common teratogenic defects caused by cocaine include hydronephrosis, cleft palate, polydactyly, and down syndrome. Cocaine as a drug has a low molecular
Cocaine
Chemical compound found in some species of mushrooms
cortical 5HT2A increases extracellular glutamate release in the synaptic cleft which is reversed by selective 5-HT2A antagonists (Vollenweider et al.,
Psilocybin
Irish mythological hero
golden yellow. This hair was settled strikingly into three coils on the cleft at the back of his head. Each long loose-flowing strand hung down in shining
Cú_Chulainn
Member of the British royal family (born 1965)
medical research charity coordinating funds in wound healing, burns and cleft research. In 2003, she succeeded Queen Elizabeth the Queen Mother as patron
Sophie,_Duchess_of_Edinburgh
Roman statesman and lawyer (106–43 BC)
that the name was originally given to one of Cicero's ancestors who had a cleft in the tip of his nose resembling a chickpea. The famous family name of
Cicero
Primary type of cell found in the epidermis
DNA-binding domain are associated with ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome. The transcriptome of p63 mutant keratinocytes
Keratinocyte
Growth of thymus tissue elsewhere in the body
of neck masses in children, including: thyroglossal duct cyst. branchial cleft cyst. dermoid cyst. inflammatory lymphadenitis. salivary gland infection
Ectopic_thymus
the erosive activity of the once larger Erkyupryia River. It transformed the marble clefts into a deep-water cave, the ceiling of which eroded through
Marvelous_Bridges
Country in Eastern Europe
Running on empty" National Geographic Magazine March 1993 Ivan Katchanovski: Cleft Countries: Regional Political Divisions and Cultures in Post-Soviet Ukraine
Ukraine
Ancient Roman goddess of love, sex and fertility
Dolphin", 19th century, lithograph Venus in nude art history Love goddess Cleft of Venus Dimples of Venus Astrological planet Venus Hottentot Venus Sailor
Venus_(mythology)
Psychedelic drug
vesicular release, the resulting concentration of serotonin in the synaptic cleft, to which serotonin receptors are exposed, is estimated to be about 300 μmol/L
Dimethyltryptamine
Species of mammal
bog hummocks, in the cracks of vacant mud buildings, in rock piles, rock clefts, and even in magpie nests. Males and females typically live apart, but close
Stoat
Impairments, activity limitations, and participation restrictions
congenital anomalies or impairments, such as weasel-arm, clubfoot, and cleft conditions. Ironically, among these, the practice of infanticide or the
Disability
Central nervous system stimulant
Neurotransmitter transporter Receptor Neurotransmitter Axon terminal Synaptic cleft Dendrite In the absence of caffeine and when a person is awake and alert
Caffeine
muscular student with a Mohawk hairstyle, a scar over his left eye and a cleft chin. Nendo is the only student at PK Academy whose mind Saiki cannot read
List of The Disastrous Life of Saiki K. characters
List_of_The_Disastrous_Life_of_Saiki_K._characters
hung from the ceiling, while paint going over the dark wainscoting, and a cleft-slate surround gracing the Rumford firebox. Upstairs, the drywall has been
List of This Old House episodes (seasons 11–20)
List_of_This_Old_House_episodes_(seasons_11–20)
Research paradigm in behavioural genetics
inheritance of undesirable traits, whether physical such as club foot or cleft palate, or psychological such as alcoholism, bipolar disorder and criminality
Biological_determinism
American amateur parachute jumper (1932-1966)
Auyán-tepui, the plateau in Venezuela from which Angel Falls drops from a cleft near the summit. For this accomplishment he was interviewed on the Today
Nick_Piantanida
Ancient Roman novel by Apuleius
clumps of wool from thorn bushes nearby. Venus next requests water from a cleft high beyond mortal reach. An eagle gathers the water for Psyche. Next, Psyche
The_Golden_Ass
German social philosopher (1929–2026)
born in Düsseldorf, Rhine Province, on 18 June 1929. He was born with a cleft palate and had corrective surgery twice in childhood. Habermas later argued
Jürgen_Habermas
Taiwanese-American biostatistician and epidemiologist
A. (1995-04-01). "Association Study of Transforming Growth Factor Alpha (TGFα) TaqI Polymorphismand Oral Clefts: Indication of Gene-Environment Interaction
Shih-Jen_Hwang
Collection of notable objects
reconstructive plastic surgery. His specialty was repairing congenital anomalies, cleft lip and palates, and club foot. He also collected medical oddities, tumors
Cabinet_of_curiosities
Literary fairy tale by Johann Wolfgang von Goethe
ferryman takes the gold up to a high place, and deposits it in a rocky cleft, where it is discovered by a green snake. The snake eats the gold and becomes
The Green Snake and the Beautiful Lily
The_Green_Snake_and_the_Beautiful_Lily
Species of mammal
riverbanks, as well as in ditches, depressions and gutters, and in rock clefts and neglected human environments. Red foxes prefer to dig their burrows
Red_fox
American physician and academic (1950–2025)
Site Mutation (1084+1G > A): Case Report", The Cleft Palate-Craniofacial Journal, 49 (1), American Cleft Palate-Craniofacial Association: 104–8, doi:10
Phyllis Gardner (clinical pharmacologist)
Phyllis_Gardner_(clinical_pharmacologist)
Development and formation of the human embryo
auditory meatus develops from the dorsal portion of the first pharyngeal cleft. Six auricular hillocks, which are mesenchymal proliferations at the dorsal
Human_embryonic_development
Nordic dragon type
the lead from the verb louhia ("to mine, quarry, shatter" etc), to lovi ("cleft, crack"), which then connects to the trait that the dragon would drill into
Flogdrake
South Korean actress (born 1978)
from the bag she designed to Operation Smile, a NGO that performs cleft lip and cleft palate surgery and delivers postoperative and ongoing medical therapies
Ha_Ji-won
and luxuriant woods; on their slopes are copious vineyards, and in the clefts of the rocks numerous bees, feeding on their aromatic plants, deposit their
Timeline of the name Palestine
Timeline_of_the_name_Palestine
First season of the One-Punch Man anime television series
years earlier that pushed him to become a hero; after saving a boy with a cleft-chin from Crablante, Saitama resolved to become a hero but became too powerful
One-Punch_Man_season_1
used to automatically evaluate the outcome of maxillo-facial surgery or cleft palate therapy in regard to facial attractiveness or age appearance. AI
Artificial intelligence in healthcare
Artificial_intelligence_in_healthcare
Part of an animal that coordinates actions and senses
between the presynaptic and postsynaptic membranes, called the synaptic cleft. The neurotransmitter then binds to receptors embedded in the postsynaptic
Nervous_system
Germanic goddess
white, who at Easter, at the season of returning spring, show themselves in clefts of the rock and on mountains, are suggestive of the ancient goddess. In
Ēostre
Central nervous system stimulant
the presynaptic neuron, and their subsequent release into the synaptic cleft by the phosphorylated transporters. Other transporters that methamphetamine
Methamphetamine
Mythologically significant animal of the Western Hemisphere
fleshy lips, almond-shaped eyes, and a cleft head similar – it is said – to that of the male jaguar which has a cleft running vertically the length of its
Jaguars in Mesoamerican cultures
Jaguars_in_Mesoamerican_cultures
Monoamine neurotransmitter
drugs inhibit the re-uptake of serotonin, making it stay in the synaptic cleft longer. The tricyclic antidepressants (TCAs) inhibit the reuptake of both
Serotonin
Video game franchise
Switch). Nintendo. Nia: In the distant past, what was once a single world was cleft in twain. Plus and minus... On the surface, they were identical. These two
Xenoblade
International non-governmental organization
provide surgeries and healthcare to treat a wide range of problems, including cleft lip and palate, cataract, bowed legs (genu varum), burns and burn scars
Mercy_Ships
Class of kinase enzymes
ATP and substrate to nRTKs, catalysis of phosphate transfer occurs in a cleft between these two lobes. It was found that nRTKs have some sequence preference
Non-receptor_tyrosine_kinase
Video game series
Karnaca, which is powered by wind turbines fed by currents generated by a cleft mountain along the city's borders. In the main entries, the endings are
Dishonored_(series)
Field of studies related to crimes
physiological traits such as the measurements of cheekbones or hairline, or a cleft palate could indicate "atavistic" criminal tendencies. This approach, whose
Criminology
Indian otorhinolaryngologist, social activist and philanthropist
of several articles and two books, Histopathological Study of Middle Ear Cleft and its Clinical Applications and Head and Neck Cancer. He was one among
Lakhumal_Hiranand_Hiranandani
Neanderthal fossils
struggle to argue "that a rickety Cossack of 1814 would have holed up in the clefts of the rock of Gibraltar." Final recognition that Neanderthals were a distinct
Neanderthal_1
CNS stimulant and isomer of amphetamine
(primarily NE and DA) on the synaptic cleft. ... LDX can also promote the increase of DA in the synaptic cleft by activating protein TAAR1, which produces
Dextroamphetamine
Aesthetic assessment of physical traits
Ray; Kingstone, Alan (March 2020). "Effects of Breast Size, Intermammary Cleft Distance (Cleavage) and Ptosis on Perceived Attractiveness, Health, Fertility
Physical_attractiveness
Chinese-American neuroscientist
Zika Virus". The New York Times. Retrieved September 25, 2022. "Identity Cleft". The Pennsylvania Gazette. August 28, 2017. Retrieved September 26, 2022
Guo-li_Ming
Genus of succulents
alone thrive, on these exposed geological habitats. Pachypodium root in cleft, fissures, and crevices of those rocky formations. The non-succulent roots
Pachypodium
Figure in Greek mythology
had a woman's face and breasts, and a hissing snake protruding from the cleft of her rusty-colored forehead, and it would slide into children's bedrooms
Lamia
Human chromosome
disorder Burkitt lymphoma Charcot–Marie–Tooth disease COACH syndrome Cleft lip and cleft palate Cohen syndrome Congenital hypothyroidism Fahr's syndrome Hereditary
Chromosome_8
Short skirt that usually extends to mid-thigh
sensuality from Azzedine Alaïa, whose designs reveal the wearer's every cleft and curve. [Four mini-length dresses are shown: 1. a mid-thigh-length black
Miniskirt
Human protein and coding gene
member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families
Bone_morphogenetic_protein_4
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TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
TRANSFORMING CLEFT
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