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Antiviral medication used against herpes, chickenpox, and shingles
Aciclovir, also known as acyclovir, is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox
Aciclovir
Antiviral medication
appears to be safe. It is a prodrug, which works after being converted to aciclovir in a person's body. Valaciclovir was patented in 1987 and came into medical
Valaciclovir
Viral disease caused by herpes simplex viruses
help with the symptoms. Treatments with antiviral medication such as aciclovir or valaciclovir can lessen the severity of symptomatic episodes. Worldwide
Herpes
Human viral disease
those at increased risk of complications, antiviral medication such as aciclovir is recommended. Chickenpox occurs in all parts of the world. In 2013,
Chickenpox
Antiviral medicine used to treat herpes simplex virus
trade names Viru-Merz and Viru-Merz Serol. Its performance is similar to aciclovir. Like rimantadine, amantadine, and adapromine, tromantadine is a derivative
Tromantadine
Viral disease caused by the varicella zoster virus
occurs, its severity. If shingles develops, antiviral medications such as aciclovir can reduce the severity and duration of disease if started within 72 hours
Shingles
Medical condition
For herpes the treatment of choice is aciclovir. If encephalitis is suspected, empiric treatment with IV aciclovir is often warranted. Surgical management
Viral_meningitis
Formulary by the World Health Organization
Cefotaxime Ceftriaxone Chloramphenicol Gentamicin Complementary: Meropenemα Aciclovir Complementary: Normal immunoglobulinα Neostigmine Complementary: Pyridostigmineα
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
Systematic naming of drugs
drugs within the class include in their generic names. For example, "aciclovir" can be identified as an antiviral drug because its name contains the
Drug_nomenclature
Muscle relaxant medication
(amiodarone, mexiletine, propafenone, verapamil), cimetidine, famotidine, aciclovir, ticlopidine and oral contraceptives) is contraindicated. Concomitant
Tizanidine
Infectious agent that replicates in cells
nucleoside analogues are aciclovir for Herpes simplex virus infections and lamivudine for HIV and hepatitis B virus infections. Aciclovir is one of the oldest
Virus
Chemical compound
daily, in contrast to aciclovir, valaciclovir and other antivirals. A study has found that it is more effective than aciclovir, but this has been disputed
Brivudine
Compound that is metabolized into a pharmacologically active drug
Examples Type I Intracellular Type IA Therapeutic target tissues/cells Aciclovir, fluorouracil, cyclophosphamide, diethylstilbestrol diphosphate, L-DOPA
Prodrug
Chemical compound
which is known as the principal metabolite of the antiviral medication aciclovir (and its prodrug valaciclovir), and has been suggested as the causative
9-Carboxymethoxymethylguanine
Official generic name for a pharmaceutical drug or active ingredient
(e.g., darunavir) -ciclovir for bicyclic heterocycle antivirals (e.g., aciclovir and famciclovir) The term stem is not used consistently in linguistics
International nonproprietary name
International_nonproprietary_name
Region of England
manufactured by Wellcome in 1987 in Kent; they also introduced Zovirax (aciclovir), and the naturally occurring digoxin, a cardiac glycoside. After a plane
South_East_England
Medical condition
Chemical structure of aciclovir
Neonatal_meningitis
Inflammation of membranes around the brain
varicella zoster virus may respond to treatment with antiviral drugs such as aciclovir. There are no clinical trials that have specifically addressed whether
Meningitis
Biochemical compound
(ddC) — HIV guanosine and deoxyguanosine analogues: abacavir (ABC) — HIV aciclovir — antiviral entecavir (ETV) — hepatitis B virus ganciclovir — Cytomegalovirus
Nucleoside_analogue
Chemical compound
other nucleoside analogues, such as the more widely used aciclovir. A difference between aciclovir and penciclovir is that the active triphosphate form of
Penciclovir
20th episode of the 5th season of House
suggests that she has melioidosis. The team start her on an IV drip and aciclovir, which works, until she starts gasping. Thirteen suggests polyserositis
Simple_Explanation
Common viral infectious disease
replication. There is little evidence to support the use of antivirals such as aciclovir and valacyclovir, although they may reduce initial viral shedding. Antivirals
Infectious_mononucleosis
symptoms, with typical early symptoms followed by a characteristic rash. Aciclovir Yes Alphavirus Chikungunya Laboratory criteria include a decreased lymphocyte
List_of_infectious_diseases
the virus in 1932, 21 of which led to death. Early treatment including aciclovir can improve prognosis. Aspergillosis, invasive pulmonary form Fungal Opportunistic
List of human disease case fatality rates
List_of_human_disease_case_fatality_rates
Inflammation of the eye
by herpes simplex viruses, can be serious and requires treatment with aciclovir. Acute hemorrhagic conjunctivitis is a highly contagious disease caused
Conjunctivitis
Epigenetic modification of HSV genetic code
The related valaciclovir Aciclovir triphosphate is the L-valine ester prodrug of aciclovir, which is thus converted to aciclovir in the liver.[citation
HSV_epigenetics
Facial paralysis
generally physician dependent. One review found that antivirals (such as aciclovir) are ineffective in improving recovery from Bell's palsy beyond steroids
Bell's_palsy
698-70-4 C8H10N4O2 caffeine 58–08–2 C8H11NO tyramine 51–67–2 C8H11N5O3 aciclovir 59277–89–3 C8H16 (1R,3R)-1,2,3-Trimethylcyclopentane C8H16O2 cyclohexanedimethanol
Glossary_of_chemical_formulae
Increase in lymphocytes within cerebrospinal fluid
Intravenous aciclovir, can be used to prevent viral replication, and in the event of persistent lymphocytic pleocytosis, higher doses of aciclovir can also
Lymphocytic_pleocytosis
nucleoside analogues are aciclovir for herpes virus infections and lamivudine for HIV and hepatitis B virus infections. Aciclovir is one of the oldest and
Introduction_to_viruses
Chemical compound
quinolones, penicillins, methotrexate, zidovudine, ganciclovir, lorazepam, and aciclovir. In all these interactions, the excretion of these drugs is reduced due
Probenecid
Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes simplex, chickenpox, varicella zoster virus GSK guanosine analogue
List_of_antiviral_drugs
Antiviral drug
cytomegalovirus retinitis. Cidofovir has also shown efficacy in the treatment of aciclovir-resistant HSV infections. Cidofovir has also been investigated as a treatment
Cidofovir
Medication used to treat a viral infection
antivirals include aciclovir which is used to treat herpes simplex virus, and letermovir which is used to treat cytomegalovirus. Aciclovir functions by competitively
Antiviral_drug
Medical condition
shedding in immunocompromised individuals. Treatment is with systemic aciclovir. Strawberry tongue, or raspberry tongue, is glossitis which manifests
Glossitis
Inflammation of the mouth, lips, and gums, often due to herpes infection
Antiviral drugs are used to treat herpetic gingivostomatitis such as aciclovir, valaciclovir, famciclovir, and in resistance cases foscarnet can be used
Herpetic_gingivostomatitis
Cheilitis characterized by inflammation of one or both of the corners of the mouth
in the same way as a cold sore, with topical antiviral drugs such as aciclovir. 22% of cases of angular cheilitis are due to irritants. Saliva contains
Angular_cheilitis
Pharmaceutical drug classification
Sulfonamides, combinations D06BB01 Idoxuridine D06BB02 Tromantadine D06BB03 Aciclovir D06BB04 Podophyllotoxin D06BB05 Inosine D06BB06 Penciclovir D06BB07 Lysozyme
ATC_code_D06
Inflammation of the uvea of the eye
of herpetic uveitis, anti-viral medications, such as valaciclovir or aciclovir, may be administered to treat the causative viral infection. The prognosis
Uveitis
Protein family
infected cells only. Such antivirals include: Purine analogues of guanine: Aciclovir, Famciclovir, Ganciclovir, Penciclovir, Valaciclovir, Valganciclovir Vidarabine
Thymidine kinase from herpesvirus
Thymidine_kinase_from_herpesvirus
Medical condition
results from inability of the corneal epithelium to heal. But on the viral aciclovir eye ointment q.i.d can be used together a systemic antiviral drug t.d
Herpes_simplex_keratitis
discoveries in which women played a major role. Aciclovir Gertrude B. Elion contributed to the development of aciclovir, an antiviral drug used for the treatment
List of inventions and discoveries by women
List_of_inventions_and_discoveries_by_women
Rare but severe and contagious disseminated infection
[citation needed] It can be treated with systemic antiviral drugs, such as aciclovir or valganciclovir. Foscarnet may also be used for immunocompromised host
Eczema_herpeticum
Type of warning that appears on the package insert for certain prescription drugs
used its power to mandate a warning on fluoroquinolones, ceftriaxone, aciclovir, and pioglitazone. Health Canada terms its version of boxed warnings "serious
Black_box_warning
Cryptotethya crypta, were the basis for the synthesis of zidovudine (AZT), aciclovir (Cyclovir), cytarabine (Depocyt), and cytarabine derivative gemcitabine
Sponge_isolates
Species of virus
thymidine kinase gene or DNA polymerase gene have caused resistance to aciclovir. However, most of the mutations occur in the thymidine kinase gene rather
Herpes_simplex_virus
Agent that deactivates or destroys viruses
Overall, the notion of virucide differs from an antiviral drug such as Aciclovir, which inhibits the proliferation of the virus inside the body. CDC's
Virucide
Pain due to peripheral nerve damage following infection by the shingles virus
postherpetic neuralgia (PHN) found no significant difference between placebo and aciclovir. Additionally, there was no significant difference in preventing the incidence
Postherpetic_neuralgia
Touitou, E. (1999) A Clinical Evaluation of a Novel Liposomal Carrier for Aciclovir in the Topical Treatment of Recurrent Herpes Labialis. Oral Surg. Oral
Ethosome
Formulary
Cefotaxime Ceftriaxone Chloramphenicol Gentamicin Complementary: Meropenemα Aciclovir Complementary: Normal immunoglobulinα Neostigmine Complementary: Pyridostigmineα
WHO Model List of Essential Medicines for Children
WHO_Model_List_of_Essential_Medicines_for_Children
Toxicity in the kidneys
cyclophosphamide, amphotericin B Tubular obstruction: sulphonamides, methotrexate, aciclovir, diethylene glycol, triamterene. Main article : Acute interstitial nephritis
Nephrotoxicity
(albendazole) Zinacef (cefuroxime) Zinnat (cefuroxime axetil) Zovirax (aciclovir) Zyban (bupropion hydrochloride) Ambirix (for hepatitis A (inactivated)
List_of_GSK_plc_products
Topics referred to by the same term
native language spoken by the Pit River people of present-day California Aciclovir, an antiviral drug ACV, an astronomical notation for an Alpha2 Canum Venaticorum
ACV
Medical condition
are no reports of successful treatments using antiviral drugs such as aciclovir. Due to the concomitant presence of bladder disorders, gastrointestinal
Chronic prostatitis/chronic pelvic pain syndrome
Chronic_prostatitis/chronic_pelvic_pain_syndrome
agents. The list is up-to-date as of January 2024. Acenaphthene Acepyrene Aciclovir Acridine orange Acriflavinium chloride Acrylic acid Acrylic fibres
IARC_group_3
Pharmaceutical drug classification
this list, which follows the WHO version. J05AA01 Metisazone J05AB01 Aciclovir J05AB02 Idoxuridine J05AB03 Vidarabine J05AB06 Ganciclovir J05AB09 Famciclovir
ATC_code_J05
Pharmaceutical drug classification
S01AB05 Sulfafenazol S01AD01 Idoxuridine S01AD02 Trifluridine S01AD03 Aciclovir S01AD05 Interferon S01AD06 Vidarabine S01AD07 Famciclovir S01AD08 Fomivirsen
ATC_code_S01
Science that studies the disease called herpes
innovation, except for the development of their respective prodrugs (Aciclovir, Famciclovir, Valacilovir..). Drawbacks such as poor bioavailability or
Herpes_simplex_research
Chemical compound
of the eye. A Cochrane Systematic Review showed that trifluridine and aciclovir were a more effective treatment than idoxuridine or vidarabine, significantly
Trifluridine
Enzyme found in most living cells
structures of thymidine kinase substrate analogs AZT Stavudine Idoxuridine Aciclovir Ganciclovir Other thymidine analogues, for instance Idoxuridine (ATC:
Thymidine_kinase
(INN) acexamic acid (INN) Aches-N-Pain Achromycin Achromycin V Aci-jel aciclovir (INN) acifran (INN) Acihexal Acilac Aciphex acipimox (INN) acitazanolast
List_of_drugs:_Ac
British medical doctor (1934–2024)
the cause of Q fever. Other research included studies on the antiviral aciclovir. In August 1978, five years after returning from Bangladesh, Geddes diagnosed
Alasdair_Macintosh_Geddes
(ranitidine) was launched by Glaxo; and the antiviral herpes treatment Zovirax (aciclovir) was launched by Wellcome. In 1991 SmithKline Beecham launched Seroxat/Paxil
Pharmaceutical industry in the United Kingdom
Pharmaceutical_industry_in_the_United_Kingdom
Mainstream medical research into cancer treatment
with introducing thymidine kinase in gliomas, making them susceptible to aciclovir, are in their experimental stage. Epigenetics is the study of heritable
Experimental_cancer_treatment
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