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Glycopeptide antibiotic used to treat various cancers
Bleomycin is a medication primarily used to treat cancer. This includes Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, ovarian cancer
Bleomycin
Protein-coding gene in the species Homo sapiens
Bleomycin hydrolase is an enzyme that in humans is encoded by the BLMH gene. Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly
Bleomycin_hydrolase
Medical condition
may include salicylic acid, cryotherapy, chemo-based fluorouracil or bleomycin, and surgical removal. The skin atop the lesion should generally be removed
Plantar_wart
Treatment of cancer using drugs that inhibit cell division or kill cells
cell division. The most important subgroup is the anthracyclines and the bleomycins; other prominent examples include mitomycin C and actinomycin. Among the
Chemotherapy
Procedure to treat vascular anomalies
traditional approaches.[citation needed] Bleomycin electrosclerotherapy consists of locally delivering the sclerosant bleomycin and applying short high voltage
Sclerotherapy
Species of bacterium
antibiotics called the bleomycins. Examples of the bleomycins in clinical use include bleomycin A2 (also known as bleomycin) and bleomycin A5 (also known as
Streptomyces_verticillus
Chemotherapy regimen used to treat Hodgkin lymphoma
(also known as doxorubicin/hydroxydaunorubicin, designated as H in CHOP) Bleomycin Vinblastine Dacarbazine (similar to procarbazine, designated as P in MOPP
ABVD
Medical condition
characterized by linear hyperpigmented streaks are seen on the chest and back. Bleomycin List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo
Scratch_dermatitis
Small, rough growth resembling a cauliflower or a solid blister
compounding pharmacies. Bleomycin — A more potent chemotherapy drug, can be injected into deep warts, destroying the viral DNA or RNA. Bleomycin is notably not
Wart
Glycopeptide antibiotic used to treat various cancers
Pingyangmycin (also known as bleomycin A5) is an antitumor glycopeptide antibiotic belonging to the bleomycin family, which is produced by Streptomyces
Pingyangmycin
Chemical compound
one of the phleomycins from Streptomyces verticillus belonging to the bleomycin family of antibiotics. It is a broad-spectrum antibiotic that is effective
Zeocin
Chemical compound
pulmonary fibrosis. Of these, the bleomycin model is the most widely used model of pulmonary fibrosis. In this model, bleomycin administration results in oxidative
Pirfenidone
Cellular state
bleomycin. Cell death occurs as it would in apoptosis, but certain apoptotic mechanisms are not utilized when in the presence of bleomycin. Bleomycin
Pseudoapoptosis
the potential to cause hearing loss. Such agents include cisplatin and bleomycin. Cisplatin is known as a platinum coordination complex. Carboplatin and
Ototoxic_medication
Class of antibiotic drugs
and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin. Vancomycin is used if infection with methicillin-resistant Staphylococcus
Glycopeptide_antibiotic
Medical condition
flagellate dermatitis and shiitake mushroom (Lentinula edodes) ingestion. Bleomycin ingestion may also cause similar findings. On physical exam, one key difference
Shiitake_mushroom_dermatitis
Medical intervention
reached clinical use by utilizing drugs such as bleomycin or cisplatin). Electrochemotherapy with bleomycin was used to treat a patient for the first time
Electrochemotherapy
Class of drugs used to treat malignant tumors
fibrosis, with key drugs including bleomycin, carmustine, mitomycin C, methotrexate, and gefitinib. Long-term high-dose bleomycin use can cause interstitial pneumonia
Antineoplastic
Type of blood and immune-system cancer
inhibitors, nivolumab and pembrolizumab. Adding nivolumab to AVD (ABVD without bleomycin) regimen significantly increases the progression-free survival. For Hodgkin
Hodgkin_lymphoma
Chemotherapy medication
component of certain chemotherapy regimens, particularly when used with bleomycin and methotrexate in VBM chemotherapy for Stage IA or IIA Hodgkin lymphomas
Vinblastine
Class of antibiotics
effects of casts and azotaemia in the urine are observed in most patients. Bleomycin is a polypeptide (more specifically a glycopeptide) antibiotic derived
Polypeptide_antibiotic
neuropathy. There are several modifications of CEPP. In combination with bleomycin, this regimen is called CEPP (B). With the further addition of the anti-CD20
CEPP
Drugs that are useful against cancer
Methotrexate Nelarabine Pemetrexed Tioguanine (formerly Thioguanine) Actinomycin Bleomycin Carboplatin Cisplatin Dicycloplatin Oxaliplatin Nedaplatin Satraplatin
List of chemotherapeutic agents
List_of_chemotherapeutic_agents
Pharmaceutical drug
Pharmaceuticals compared ABVD (a combination of the chemotherapy drugs doxorubicin, bleomycin, vinblastine, and dacarbazine) versus A+AVD (a combination of brentuximab
Brentuximab_vedotin
Chemical compound
Pitt–Hopkins syndrome, cholestatic liver disease, multiple sclerosis, bleomycin-induced lung fibrosis, and COVID-19 caused ARDS. It was designated as
Sobetirome
Medical condition in which spasm of arteries causes episodes of reduced blood flow
Cytotoxic drugs – particularly chemotherapeutics and most especially bleomycin Cyclosporin Bromocriptine Ergotamine Sulfasalazine Anthrax vaccines whose
Raynaud_syndrome
Pharmaceutical drug classification
Pirarubicin L01DB09 Valrubicin L01DB10 Amrubicin L01DB11 Pixantrone L01DC01 Bleomycin L01DC02 Plicamycin L01DC03 Mitomycin L01DC04 Ixabepilone L01DC05 Utidelone
ATC_code_L01
Relevance of metallic elements in biomedical contexts
emission tomography. Cobalt(III): 57Cobalt(III) is used with the compound bleomycin (BLM) (Figure 1), which is an antibiotic, to selectively be taken up by
Metals_in_medicine
Medication used as chemotherapy and to suppress the immune system
Matthay RA (March 1990). "Pulmonary effects of cytotoxic agents other than bleomycin". Clinics in Chest Medicine. 11 (1): 31–54. doi:10.1016/S0272-5231(21)00670-5
Cyclophosphamide
Species of bacterium
species from the genus of Streptomyces. Streptomyces mobaraensis produces bleomycin, detoxin, piericidin A, piericidin B, reticulol and transglutaminase.
Streptomyces_mobaraensis
Radiologic sign indicating pulmonary fibrosis (lung scarring)
[citation needed] Various medications (such as amiodarone, methotrexate, bleomycin, or TKIs) have also been linked to causing pulmonary damage leading to
Honeycombing
Class of chemical compounds
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Indolocarbazole
Chemical compound
products. Unlike other anticancer agents like mitomycin C, streptonigrin, bleomycin, and the anthracyclines, lomustine does not require bioactivation to react
Lomustine
Type of cancer
[COP], vincristine, doxorubicin, prednisone, etoposide, cyclophosphamide, bleomycin VAPEC-B). Alemtuzumab (Campath), a monoclonal antibody that attacks white
Leukemia
Chemotherapy medication
(Adriamycin, cyclophosphamide), TAC (taxotere, AC), ABVD (Adriamycin, bleomycin, vinblastine, dacarbazine), BEACOPP, CHOP (cyclophosphamide, hydroxydaunorubicin
Doxorubicin
Widely used enzyme extracted from papayas
cleavage of the propeptide is required for enzyme activation, although bleomycin hydrolase is cytosolic in fungi and mammals. Papain-like cysteine proteinases
Papain
Medication
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Decitabine/cedazuridine
Medical condition
Huma (2011). "Successful Treatment of Periungual Warts with Diluted Bleomycin Using Translesional Multipuncture Technique: A Pilot Prospective Study"
Periungual_wart
Cancer involving the vulva
given in melanoma of the vulva. Electrochemotherapy with intravenous bleomycin administered to heavily pre-treated patients showed a reasonable tumor
Vulvar_cancer
American cyclist (born 1971)
standard treatment for Armstrong's cancer was a "cocktail" of the drugs bleomycin, etoposide, and cisplatin (or Platinol) (BEP). The first chemotherapy
Lance_Armstrong
Chemotherapy medication used for several cancer types
lymphoma, it is often delivered as part of the BEACOPP regimen that includes bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine (tradename Oncovin)
Procarbazine
Chemotherapy medication
For Hodgkin's lymphoma, it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein. Common side effects
Dacarbazine
Gene therapy medication
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Tisagenlecleucel
Accumulation of collagen in the skin and internal organs
has been linked to exposure to gadolinium-containing radiocontrast. Bleomycin (a chemotherapeutic agent) and possibly taxane chemotherapy may cause
Systemic_scleroderma
Japanese microbiologist
through fermentation processes. In 1963, he discovered the anticancer drug bleomycin, and in 1965 he discovered kasugamycin, a compound useful in combating
Hamao_Umezawa
Classification of agents that are possibly carcinogenic to humans
violet 4B 2,2-Bis(bromomethyl)propane-1,3-diol BK polyomavirus (BKV) Bleomycin Bracken fern 1-Bromo-3-chloropropane Bromochloroacetic acid Bromodichloromethane
IARC_group_2B
Protein-coding gene in the species Homo sapiens
introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin". Am. J. Respir. Cell Mol. Biol. 28 (5): 582–91. doi:10.1165/rcmb.2002-0162OC
Hematopoietic prostaglandin D synthase
Hematopoietic_prostaglandin_D_synthase
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Nirogacestat
Chemical compound and pharmaceutical drug
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Cisplatin
syndrome Riehl melanosis Scratch dermatitis (flagellate pigmentation from bleomycin) Segmental vitiligo Shah–Waardenburg syndrome Shiitake mushroom dermatitis
List_of_skin_conditions
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Rabacfosadine
Medical condition
PVOD has also been associated with several chemotherapy regimens such as bleomycin, BCNU, and mitomycin. Chloe Temtchine, American singer-songwriter with
Pulmonary venoocclusive disease
Pulmonary_venoocclusive_disease
Chemical that inhibits the use of a metabolite
Anti-tumor antibiotics that are not anthracyclines include: Actinomycin-D Bleomycin Mitomycin-C Mitoxantrone Phototrexate Some antimetabolites can also be
Antimetabolite
Darkening of an area of skin or nails due to increased melanin
gastrointestinal polyps. Exposure to certain chemicals such as salicylic acid, bleomycin, and cisplatin. Smoker's melanosis Coeliac disease Cronkhite–Canada syndrome
Hyperpigmentation
transition metal complexes of carboxamido (deprotonated carboxamide) ligands: bleomycin (Fe), Nickel superoxide dismutase (Ni), and nitrile hydratase (Co). The
Transition metal carboxamide complex
Transition_metal_carboxamide_complex
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Carfilzomib
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Perfosfamide
Pharmaceutical drug
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Cladribine
Medical condition
regimen most commonly used in GCTs is called PEB (or BEP), and consists of bleomycin, etoposide, and a platinum-based antineoplastic (cisplatin). Targeted
Germ_cell_tumor
Pharmaceutical compound
targets extracellular matrix production in fibroblasts and ameliorates bleomycin-induced pulmonary fibrosis in mice". Naunyn-Schmiedeberg's Archives of
FOXO4-DRI
Brain tumor of pituitary gland embryonic tissue
experimental therapies using intracavitary phosphorus-32, yttrium, or bleomycin delivered via an external reservoir are sometimes employed, especially
Craniopharyngioma
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Bisantrene
Chemotherapy medication
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Fluorouracil
Chemotherapy medication
multiforme. It is often given in combination with other drugs (such as bleomycin in treating testicular cancer). It is also sometimes used in a conditioning
Etoposide
mouse model of bleomycin-induced lung fibrosis. Orotracheal application of CCN4 neutralizing antibodies to the lung ameliorates bleomycin-induced lung fibrosis
WNT1-inducible-signaling pathway protein 1
WNT1-inducible-signaling_pathway_protein_1
Topics referred to by the same term
Ligand Model, a toxicology tool Black lipid membranes, in cell biology Bleomycin, a cancer medication Bloom syndrome protein, in genetics BLM protein,
BLM
Chemical compound
Kasugamycin was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug that prevent growth of a fungus causing rice blast disease
Kasugamycin
Protein found in humans
deletion of Ctgf in fibroblasts and smooth muscle cells greatly reduces bleomycin-induced skin fibrosis. In addition to fibrosis, aberrant CTGF expression
Connective tissue growth factor
Connective_tissue_growth_factor
Medical condition
is caused by many chemotherapeutic agents (especially the antibiotics bleomycin, and daunorubicin) and the alkylating agents (cyclophosphamide and busulfan)
Chemotherapy-induced hyperpigmentation
Chemotherapy-induced_hyperpigmentation
Vinblastine, an alkaloid cell toxin Vincristine, another alkaloid cell toxin Bleomycin, another anti-tumor antibiotic Etoposide, a DNA toxin Prednisone, a corticosteroid
Stanford_V
Cell based gene therapy
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Brexucabtagene_autoleucel
Use of oxygen as a medical treatment
Oxygen therapy is not recommended for people with pulmonary fibrosis or bleomycin-associated lung damage. ARDS caused by acid aspiration may be exacerbated
Oxygen_therapy
INN) bizelesin (INN) Bizengri Bkemv Blenoxane (Bristol-Myers Squibb) bleomycin (INN) Bleph-10 (Allergan) Blephamide (Allergan) blinatumomab (USAN, INN)
List_of_drugs:_Bi–Bo
Pharmaceutical drug
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Tagraxofusp
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Copanlisib
Gene therapy medication
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Lisocabtagene_maraleucel
injection, as marketed in the United States c. 1993. Clockwise from center: bleomycin, an antitumor antibiotic; vincristine, a spindle poison; dacarbazine,
History of cancer chemotherapy
History_of_cancer_chemotherapy
Medical drug glass
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Phosphoinositide 3-kinase inhibitor
Phosphoinositide_3-kinase_inhibitor
Chemotherapy regimen for colorectal cancer treatment
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
FOLFIRI
Medical condition
combination of paclitaxel and carboplatin (TC) and the combination of bleomycin, etoposide, and cisplatin (BEP). Immunotherapy's adoption in platinum-resistant
Ovarian squamous cell carcinoma
Ovarian_squamous_cell_carcinoma
Alkylating type cancer drug
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Melphalan_flufenamide
Genus of bacteria
used in other medical treatments: migrastatin (from S. platensis) and bleomycin (from S. verticillus) are antineoplastic (anticancer) drugs; boromycin
Streptomyces
Cancerous tumour in a bone
rescue, intra-arterial cisplatin, adriamycin, ifosfamide with mesna, BCD (bleomycin, cyclophosphamide, dactinomycin), etoposide, and muramyl tripeptide. Rotationplasty
Osteosarcoma
Organism that thrives at relatively high temperatures
these organisms are exposed to the DNA damaging agents UV irradiation, bleomycin or mitomycin C, species-specific cellular aggregation is induced. In S
Thermophile
Medication given to people before they have a bone marrow transplant
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Treosulfan
Disease that causes scarring of the lungs
Infections, including COVID-19 Certain medications, e.g. amiodarone, bleomycin (pingyangmycin), busulfan, apomorphine, and nitrofurantoin Radiation therapy
Pulmonary_fibrosis
Medication
Chlorpropamide Phenytoin Theophylline Cyclophosphamide, doxorubicin, bleomycin, procarbazine, mechlorethamine Co-administration of the following drugs
Allopurinol
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Idelalisib
Mouse myoblast cell line
2025. Kamal, Michael; Joanisse, Sophie; Parise, Gianni (1 April 2024). "Bleomycin-treated myoblasts undergo p21-associated cellular senescence and have
C2C12
Human disease
removal of cystic hygroma are surgery or sclerosing agents, which include: Bleomycin Doxycycline Ethanol (pure) Picibanil (OK-432) Sodium tetradecyl sulfate
Cystic_hygroma
American biochemist
work with Arthur on studying the mechanism of how the anticancer drug bleomycin interferes with DNA replication. Sylvy married Arthur Kornberg in 1943
Sylvy_Kornberg
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Rucaparib
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Pentostatin
Type of tumor
therapy, and clinical trials. Among the treatments, the BEP combination (bleomycin, etoposide, cisplatin) is the standard chemotherapy treatment method for
Extracranial_germ_cell_tumor
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Clofarabine
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Umbralisib
Protein-coding gene in the species Homo sapiens
JS (Dec 1998). "An evolutionarily conserved cysteine protease, human bleomycin hydrolase, binds to the human homologue of ubiquitin-conjugating enzyme
UBE2I
Combination medication
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Bifikafusp alfa/onfekafusp alfa
Bifikafusp_alfa/onfekafusp_alfa
Chemical compound
Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# (Pingyangmycin) Ixabepilone Mitomycin Plicamycin Utidelone) Photosensitizers/PDT
Talazoparib
Group of antibiotics
from MMC-producing microorganisms protects from the lethal effect of bleomycin: crystallographic analysis to elucidate the binding mode of the antibiotic
Mitomycins
BLEOMYCIN
BLEOMYCIN
BLEOMYCIN
BLEOMYCIN
Boy/Male
Bengali, Hindu, Indian, Tamil
Lord Shiva
Surname or Lastname
English
English : metonymic occupational name for a weaver or textile worker, from Middle English wyndhows ‘winding house’. Compare Winder 1.
Boy/Male
Muslim
Latch, Door lock
Girl/Female
Hindu
One who save the world
Female
Greek
(Ξανθίππη) Feminine form of Greek Xanthippos, XANTHIPPE means "yellow horse." In mythology, this is the name of a daughter of Doros.
Girl/Female
Latin American
Born ninth. Traditionally given to the ninth child in a large family.
Girl/Female
Australian, Hebrew
Ewe
Boy/Male
American, Australian, British, Chinese, Christian, English, French
Round; Lumpy; Gentle; Barrel-maker
Boy/Male
Assamese, Hindu, Indian, Kannada, Telugu
King of Wisdom
Female
Arthurian
, noble cheer, or, noble maiden.
BLEOMYCIN
BLEOMYCIN
BLEOMYCIN
BLEOMYCIN
BLEOMYCIN