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COBRATOXIN

  • Cobratoxin

    • Chemical compound

    α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by

    Cobratoxin

    Cobratoxin

    Cobratoxin

  • Pentobarbital

    • Short-acting barbiturate

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Pentobarbital

    Pentobarbital

    Pentobarbital

  • Paralysis

    • Loss of motor function

    Neuroprosthetics Brain–computer interface Tonic immobility Cerebral palsy Cobratoxin Obdormition Narcolepsy Cataplexy Locked-in syndrome – Condition in which

    Paralysis

    Paralysis

  • Lean (drug)

    • Recreational drug beverage

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Lean (drug)

    Lean (drug)

    Lean_(drug)

  • Barbiturate

    • Class of depressant drugs derived from barbituric acid

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Barbiturate

    Barbiturate

    Barbiturate

  • Datura

    • Genus of poisonous, potentially psychoactive plants

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Datura

    Datura

    Datura

  • Datura stramonium

    • Species of flowering plant in the nightshade family

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Datura stramonium

    Datura stramonium

    Datura_stramonium

  • Sodium thiopental

    • Barbiturate general anesthetic

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Sodium thiopental

    Sodium thiopental

    Sodium_thiopental

  • Atropa bella-donna

    • Deadly nightshade, a flowering plant

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Atropa bella-donna

    Atropa bella-donna

    Atropa_bella-donna

  • Ketamine

    • Dissociative anesthetic and anti-depressant

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Ketamine

    Ketamine

    Ketamine

  • Choline m-bromophenyl ether

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Choline m-bromophenyl ether

    Choline m-bromophenyl ether

    Choline_m-bromophenyl_ether

  • Bupropion

    • Medication mainly used for depression and smoking cessation

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Bupropion

    Bupropion

    Bupropion

  • Monocled cobra

    • Species of snake

    major α-neurotoxin in the monocled cobra's venom is a long neurotoxin, α-cobratoxin; the minor α-neurotoxin is different from cobrotoxin in one residue. The

    Monocled cobra

    Monocled cobra

    Monocled_cobra

  • Phencyclidine

    • Dissociative hallucinogenic drug, mostly used recreationally

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Phencyclidine

    Phencyclidine

    Phencyclidine

  • Genetic vaccine

    • Vaccine containing nucleic acids

    "Protective immunity against alpha-cobratoxin following a single administration of a genetic vaccine encoding a non-toxic cobratoxin variant". Human Gene Therapy

    Genetic vaccine

    Genetic_vaccine

  • Rocuronium bromide

    • Non-depolarizing neuromuscular blocker

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Rocuronium bromide

    Rocuronium bromide

    Rocuronium_bromide

  • Epibatidine

    • Toxic chemical from some poison dart frogs

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Epibatidine

    Epibatidine

    Epibatidine

  • Robert Charles Hider

    • Professor of Medicinal Chemistry at King's College London

    Williams RJP, Endo T and Miyatawa T. The molecular conformation of α-cobratoxin as studied by nuclear magnetic resonance and circular dichroism. J. Mol

    Robert Charles Hider

    Robert Charles Hider

    Robert_Charles_Hider

  • Levamisole

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Levamisole

    Levamisole

    Levamisole

  • Alcohol (drug)

    • Active ingredient in fermented drinks

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Alcohol (drug)

    Alcohol (drug)

    Alcohol_(drug)

  • Nicotinic acetylcholine receptor

    • Acetylcholine receptors named for their selective binding of nicotine

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Nicotinic acetylcholine receptor

    Nicotinic acetylcholine receptor

    Nicotinic_acetylcholine_receptor

  • Polycephaly

    • Condition of having more than one head

    biotechnology company developing treatments using modified cobra venom and cobratoxin. "We" died of natural causes at age seven in June 2007. Two-headed farm

    Polycephaly

    Polycephaly

    Polycephaly

  • Agmatine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Agmatine

    Agmatine

  • Suxamethonium chloride

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Suxamethonium chloride

    Suxamethonium chloride

    Suxamethonium_chloride

  • Allopregnanolone

    • Endogenous inhibitory neurosteroid

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Allopregnanolone

    Allopregnanolone

    Allopregnanolone

  • Alpha-3 beta-4 nicotinic receptor

    • Type of nicotinic acetylcholine receptor

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Alpha-3 beta-4 nicotinic receptor

    Alpha-3_beta-4_nicotinic_receptor

  • Anticholinergic

    • Parasympathetic nervous system inhibitors

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Anticholinergic

    Anticholinergic

  • Dextromethorphan

    • Cough suppressant and dissociative drug

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Dextromethorphan

    Dextromethorphan

    Dextromethorphan

  • Pancuronium bromide

    • Aminosteroid muscle relaxant

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Pancuronium bromide

    Pancuronium bromide

    Pancuronium_bromide

  • Lecithin

    • Generic term for amphiphilic substances of plant and animal origin

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Lecithin

    Lecithin

    Lecithin

  • Choline

    • Chemical compound and essential nutrient

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Choline

    Choline

    Choline

  • Arecoline

    • Stimulant alkaloid responsible for mouth cancers

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Arecoline

    Arecoline

    Arecoline

  • Esketamine

    • Medication

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Esketamine

    Esketamine

    Esketamine

  • Vecuronium bromide

    • Muscle relaxant

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Vecuronium bromide

    Vecuronium bromide

    Vecuronium_bromide

  • Dimenhydrinate

    • Anti-emetic and antihistamine medication

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Dimenhydrinate

    Dimenhydrinate

    Dimenhydrinate

  • Cholinesterase

    • Esterase that lyses choline-based esters

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Cholinesterase

    Cholinesterase

  • Cyclizine

    • Medication for motion sickness or vertigo

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Cyclizine

    Cyclizine

    Cyclizine

  • Thiocolchicoside

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Thiocolchicoside

    Thiocolchicoside

    Thiocolchicoside

  • Cytisine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Cytisine

    Cytisine

    Cytisine

  • Acetylcholine

    • Organic chemical and neurotransmitter

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Acetylcholine

    Acetylcholine

    Acetylcholine

  • Curare

    • Group of chemical substances used as poison

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Curare

    Curare

    Curare

  • Naltrexone/bupropion

    • Medication for treatment of obesity

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Naltrexone/bupropion

    Naltrexone/bupropion

    Naltrexone/bupropion

  • Ibogaine

    • Psychoactive substance found in plants in the family Apocynaceae

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Ibogaine

    Ibogaine

    Ibogaine

  • Brugmansia

    • Genus of flowering plants in the nightshade family

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Brugmansia

    Brugmansia

    Brugmansia

  • Phosphatidylcholine

    • Class of phospholipids

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Phosphatidylcholine

    Phosphatidylcholine

    Phosphatidylcholine

  • Alpha-7 nicotinic receptor

    • Type of cell receptor found in humans

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Alpha-7 nicotinic receptor

    Alpha-7 nicotinic receptor

    Alpha-7_nicotinic_receptor

  • Snake venom

    • Highly modified saliva containing zootoxins

    cardiotoxins, and postsynaptic neurotoxins (such as α-bungarotoxin and α-Cobratoxin), which bind to acetylcholine receptors at neuromuscular junctions. Compounds

    Snake venom

    Snake venom

    Snake_venom

  • Memantine

    • Medication used to treat Alzheimer's disease

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Memantine

    Memantine

    Memantine

  • Galantamine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Galantamine

    Galantamine

    Galantamine

  • Tabernanthalog

    • Pharmaceutical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Tabernanthalog

    Tabernanthalog

    Tabernanthalog

  • Sevoflurane

    • Inhalational anaesthetic

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Sevoflurane

    Sevoflurane

    Sevoflurane

  • Tubocurarine chloride

    • Obsolete muscle relaxant

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Tubocurarine chloride

    Tubocurarine chloride

    Tubocurarine_chloride

  • Mivacurium chloride

    • Drug used in a hospital setting

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Mivacurium chloride

    Mivacurium chloride

    Mivacurium_chloride

  • Metopimazine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Metopimazine

    Metopimazine

    Metopimazine

  • Acetylcarnitine

    • Form of L-carnitine

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Acetylcarnitine

    Acetylcarnitine

    Acetylcarnitine

  • Dextromethorphan/bupropion

    • Combination medication

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Dextromethorphan/bupropion

    Dextromethorphan/bupropion

    Dextromethorphan/bupropion

  • Halothane

    • General anaesthetic

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Halothane

    Halothane

    Halothane

  • Neuromuscular-blocking drug

    • Type of paralyzing anesthetic including lepto- and pachycurares

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Neuromuscular-blocking drug

    Neuromuscular-blocking drug

    Neuromuscular-blocking_drug

  • Dextropropoxyphene

    • Withdrawn opioid medication

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Dextropropoxyphene

    Dextropropoxyphene

    Dextropropoxyphene

  • Sugammadex

    • Selective relaxant binding agent

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Sugammadex

    Sugammadex

    Sugammadex

  • Citicoline

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Citicoline

    Citicoline

    Citicoline

  • Pantothenic acid

    • Vitamin

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Pantothenic acid

    Pantothenic acid

    Pantothenic_acid

  • Muscarinic antagonist

    • Drug that binds to but does not activate muscarinic cholinergic receptors

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Muscarinic antagonist

    Muscarinic antagonist

    Muscarinic_antagonist

  • Nitrous oxide

    • Colourless non-flammable greenhouse gas

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Nitrous oxide

    Nitrous oxide

    Nitrous_oxide

  • Organophosphate

    • Organic compounds with the structure O=P(OR)3

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Organophosphate

    Organophosphate

    Organophosphate

  • Amantadine

    • Medication used to treat dyskinesia

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Amantadine

    Amantadine

    Amantadine

  • List of dangerous snakes

    • Venom and aggression rankings

    The major α-neurotoxin in Naja kaouthia venom is a long neurotoxin, α-cobratoxin; the minor α-neurotoxin is different from cobrotoxin in one residue. The

    List of dangerous snakes

    List of dangerous snakes

    List_of_dangerous_snakes

  • Cisapride

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Cisapride

    Cisapride

  • Hydroxybupropion

    • Group of stereoisomers

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Hydroxybupropion

    Hydroxybupropion

    Hydroxybupropion

  • Ropanicant

    • Neurological drug under development

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Ropanicant

    Ropanicant

    Ropanicant

  • Glycerophosphorylcholine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Glycerophosphorylcholine

    Glycerophosphorylcholine

    Glycerophosphorylcholine

  • Cholinergic

    • Agent which mimics choline

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Cholinergic

    Cholinergic

    Cholinergic

  • Pharmacology of ethanol

    • Pharmacodynamics and pharmacokinetics of ethanol

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Pharmacology of ethanol

    Pharmacology of ethanol

    Pharmacology_of_ethanol

  • Irditoxin

    • different protein-protein interaction surface; the recently described alpha-cobratoxin also forms both covalent homodimers and low-abundance covalent heterodimers

    Irditoxin

    Irditoxin

    Irditoxin

  • Arketamine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Arketamine

    Arketamine

    Arketamine

  • Bungarotoxin

    • Class of neurotoxic proteins

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Bungarotoxin

    Bungarotoxin

  • Dexbrompheniramine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Dexbrompheniramine

    Dexbrompheniramine

    Dexbrompheniramine

  • Phenylpiracetam

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Phenylpiracetam

    Phenylpiracetam

    Phenylpiracetam

  • Nifene

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Nifene

    Nifene

    Nifene

  • Stercuronium iodide

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Stercuronium iodide

    Stercuronium iodide

    Stercuronium_iodide

  • Nicotine

    • Chemical stimulant produced by some plants

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Nicotine

    Nicotine

    Nicotine

  • Alpha-3 beta-2 nicotinic receptor

    • Type of human nicotinic acetylcholine receptor

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Alpha-3 beta-2 nicotinic receptor

    Alpha-3_beta-2_nicotinic_receptor

  • Kappa-Bungarotoxin

    • Protein neurotoxin of the bungarotoxin family

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Kappa-Bungarotoxin

    Kappa-Bungarotoxin

    Kappa-Bungarotoxin

  • Ivermectin

    • Medication for parasite infestations

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Ivermectin

    Ivermectin

    Ivermectin

  • Leptodactyline

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Leptodactyline

    Leptodactyline

    Leptodactyline

  • Candocuronium iodide

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Candocuronium iodide

    Candocuronium iodide

    Candocuronium_iodide

  • Acetyl-CoA

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Acetyl-CoA

    Acetyl-CoA

    Acetyl-CoA

  • Pyrantel

    • Medication for parasitic worm infections

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Pyrantel

    Pyrantel

    Pyrantel

  • Tramadol

    • Synthetic opioid pain medication

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Tramadol

    Tramadol

    Tramadol

  • Tobacco

    • Agricultural product processed from the leaves of plants in the genus Nicotiana

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Tobacco

    Tobacco

    Tobacco

  • Droperidol

    • Antidopaminergic drug

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Droperidol

    Droperidol

    Droperidol

  • Varenicline

    • Nicotinic receptor agonist

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Varenicline

    Varenicline

    Varenicline

  • Muscarinic agonist

    • Activator of the muscarinic acetylcholine receptor

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Muscarinic agonist

    Muscarinic agonist

    Muscarinic_agonist

  • AQW-051

    • Nicotinic agonist medication

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    AQW-051

    AQW-051

    AQW-051

  • Progesterone

    • Sex hormone

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Progesterone

    Progesterone

    Progesterone

  • Xenon

    • Chemical element with atomic number 54 (Xe)

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Xenon

    Xenon

    Xenon

  • Conotoxin

    • Group of neurotoxins

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Conotoxin

    Conotoxin

    Conotoxin

  • Phenothiazine

    • Heterocyclic compound containing a ring of four carbon, one nitrogen and one sulfur atom

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Phenothiazine

    Phenothiazine

    Phenothiazine

  • 5-Hydroxyindoleacetic acid

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    5-Hydroxyindoleacetic acid

    5-Hydroxyindoleacetic acid

    5-Hydroxyindoleacetic_acid

  • Alimemazine

    • Chemical compound

    allosteric modulators) 18-MAC 18-MC α-Neurotoxins (e.g., α-bungarotoxin, α-cobratoxin, α-conotoxin, many others) ABT-126 Alcuronium Allopregnanolone Amantadine

    Alimemazine

    Alimemazine

    Alimemazine

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