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Class of proteins
CREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements
CREB
Group of transcription factors
The ATF/CREB family is a group of transcription factors, consisting of different ATFs (Activating transcription factors), CREB (cAMP response element binding
ATF/CREB
The cellular transcription factor CREB (cAMP response element-binding protein) helps learning and the stabilization and retrieval of fear-based, long-term
CREB_in_cognition
Nuclear protein that binds to CREB
CREB-binding protein, also known as CREBBP or CBP or KAT3A, (where CREB is cAMP response element-binding protein) is a coactivator encoded by the CREBBP
CREB-binding_protein
Fourth season of American Horror Story
Dolcefino Lily Rabe as Sister Mary Eunice McKee Neil Patrick Harris as Chester Creb Naomi Grossman as Pepper Grace Gummer as Penny Nelson Chrissy Metz as Barbara
American Horror Story: Freak Show
American_Horror_Story:_Freak_Show
Topics referred to by the same term
CREB regulated transcription coactivator (CRTC) may refer to the following proteins and genes: CRTC1 CRTC2 CRTC3 CREB CRTC (disambiguation) This disambiguation
CREB regulated transcription coactivator
CREB_regulated_transcription_coactivator
1980 novel by Jean M. Auel
antagonists of the Clan. The child is adopted by Iza and her eldest brother Creb. Creb is the group's "Mog-ur" or shaman, despite being deformed as a result
The_Clan_of_the_Cave_Bear
1986 film by Michael Chapman
considered deformed and a precipitant of bad luck. However, Creb intervenes, appealing to Brun that Creb's deformities also qualified him as a burden but he was
The Clan of the Cave Bear (film)
The_Clan_of_the_Cave_Bear_(film)
Mammalian protein found in Homo sapiens
CAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene. This protein binds the cAMP
CREB1
Form of behavioral dependence involving emotional symptoms
overlapping signaling cascades that diverge at the CREB transcription factor. Upregulation of CREB expression in the nucleus accumbens plays a major role
Psychological_dependence
Field of research
Some CREB-target genes, relevant for understanding alcoholism, include NPY, BDNF, Arc, and CRF. Levels of CREB and p-CREB (a highly phosphorylated CREB protein)
Molecular and epigenetic mechanisms of alcoholism
Molecular_and_epigenetic_mechanisms_of_alcoholism
Interconnected biochemical reactions releasing energy
The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle)—is a series of biochemical reactions
Citric_acid_cycle
Protein family
biochemistry, the KIX domain (kinase-inducible domain (KID) interacting domain) or CREB binding domain is a protein domain of the eukaryotic transcriptional coactivators
KIX_domain
Atypical antidepressant
no affinity for the dopamine transporter or the dopamine receptors. CREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription
Tianeptine
Cell cycle regulation pathway
membrane. AKT can have a number of downstream effects such as activating CREB, inhibiting p27, localizing FOXO in the cytoplasm, and activating phosphatidylinositol
PI3K/AKT/mTOR_pathway
Selective artificial removal of memories or associations from the mind
element-binding protein (CREB) in them. As a result, the neurons were activated in fear memory or testing far more often in both wild-type and CREB-deficient mice
Memory_erasure
Protein-coding gene in the species Homo sapiens
CREB/ATF bZIP transcription factor is a protein that in humans is encoded by the CREBZF gene. GRCh38: Ensembl release 89: ENSG00000137504 – Ensembl, May
CREB/ATF bZIP transcription factor
CREB/ATF_bZIP_transcription_factor
Neurological process
substantial evidence exists implicating the cellular transcription factor CREB (cyclic AMP responsive element-binding protein) in this process. Certain
Neuronal_memory_allocation
Need for a drug, whose discontinuation results in withdrawal symptoms
and the gene transcription factor "cAMP response element binding protein" (CREB). The nucleus accumbens (NAcc) is one brain structure that has been implicated
Substance_dependence
Protein family
E1A binding protein p300, is encoded by the EP300 gene) CBP (also known as CREB-binding protein encoded by the CREBBP) Both p300 and CBP interact with numerous
P300-CBP_coactivator_family
American neuropsychiatrist
control protein CREB (cAMP response element binding protein). In collaboration with David Glanzman and Craig Bailey, Kandel identified CREB as being a protein
Eric_Kandel
American judge (1912–1988)
Jones Crebs (January 14, 1912 – March 5, 1988) was an American jurist who was a justice of the Illinois Supreme Court. Born in Carmi, Illinois, Crebs received
Caswell_J._Crebs
Central nervous system stimulant
element binding protein (CREB), the phosphorylation of which induces its association with the histone acetyltransferase, CREB binding protein (CBP) to
Methamphetamine
Process that kills nerve cells
triggered by both glutamate exposure or hypoxic/ischemic conditions, activate a CREB (cAMP response element binding) protein shut-off, which in turn caused loss
Excitotoxicity
Protein-coding gene in the species Homo sapiens
CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (Transducer Of Regulated CREB activity 1), is a protein that in humans
CRTC1
Congenital disorder of nervous system
TBP-associated factor (TAFII130), Sp1, camp-responsive element-binding protein (CREB) and CREB-binding protein (CBP). It has been proposed that recruitment of transcription
Dentatorubral–pallidoluysian atrophy
Dentatorubral–pallidoluysian_atrophy
Chemical compound
element-binding protein (CREB). Neuroprotection that is associated with 4-PPBP increases Bcl-2 expression; Bcl-2 expression is regulated by CREB. 3-PPP Yang S,
4-PPBP
American politician
John Montgomery Crebs (April 9, 1830 – June 26, 1890) was a U.S. Representative from Illinois, as well as an officer and brigade commander in the Union
John_M._Crebs
Fictional character by Jean Auel
Brun; Ayla is adopted by Iza, the clan's medicine-woman, and her brother, Creb, the clan's "Mog-ur" (shaman). Though no one knows Ayla's age, the author
Ayla_(Earth's_Children)
Protein-coding gene in the species Homo sapiens
CREB regulated transcription coactivator 2, also known as CRTC2, is a protein which in humans is encoded by the CRTC2 gene. CRTC2, initially called TORC2
CRTC2
Field of study
genes involved in BDNF-TrkB-CREB signaling pathway. This causes enhanced phosphorylation of CREB downstream in the pathway. CREB causes enhanced acetylation
Epigenetics of cocaine addiction
Epigenetics_of_cocaine_addiction
Cell surface protein binding somatostatin and triggering intracellular changes
very susceptible to gene promoter region activation by transcription factor CREB. There are five known somatostatin receptors: SST1 and SST4 are potential
Somatostatin_receptor
Class of opioid peptides
effects of CREB and dynorphin on learned helplessness (an animal model for depression) in mice. Overexpression of dominant negative CREB (mCREB) in transgenic
Dynorphin
Mammalian protein found in Homo sapiens
transcription and interacts with cAMP-response-element-binding protein (CREB) and CREB-binding protein (CBP). It also increases transcription via interaction
TOX3
1980–2011 series of books by Jean M. Auel
worship is so ancient that Creb had to use deep meditation to find them in the Clan memories—bore female names. Goov, Creb's apprentice, also speculates
Earth's_Children
2015 studio album by Built to Spill
the Way" 4:25 4. "Some Other Song" 4:26 5. "Never Be the Same" 3:15 6. "C.R.E.B." 4:21 7. "Another Day" 3:10 8. "Horizon to Cliff" 2:44 9. "So" 4:28 10
Untethered_Moon
Persistent strengthening of synapses based on recent patterns of activity
potent transcriptional coactivator for cAMP response element binding protein (CREB). This requirement for a molecular coincidence accounts perfectly for the
Long-term_potentiation
President of the United States from 1861 to 1865
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Abraham_Lincoln
Drug mixture used mainly to treat ADHD and narcolepsy
element binding protein (CREB), the phosphorylation of which induces its association with the histone acetyltransferase, CREB binding protein (CBP) to
Adderall
Anti-obesity medication
hypothalamus and is consistent with GPCR activation leading to stimulation of CREB and Fos activity in neuronal cells. Researchers at Stanford University derived
BRINP2-related_peptide
Field of study
protein (CREB), inducing CREB-mediated changes in gene expression. With chronic alcohol intake, consumption of ethanol similarly induces CREB phosphorylation
Neuropharmacology
Heritable characteristics affecting learning
activate the ERK pathway which then modulates transcription factors like CREB. CREB then recruits a HAT to help create and stabilize the long term formation
Epigenetics in learning and memory
Epigenetics_in_learning_and_memory
Protein-coding gene in the species Homo sapiens
FOSB FOSL1 FOSL2 JDP2 c-Jun JUNB JunD BACH 1 2 BATF BLZF1 C/EBP α β γ δ ε ζ CREB 1 3 L1 CREM DBP DDIT3 GABPA GCN4 HLF MAF B sMaf F G K NFE 2 L1 L2 L3 NFIL3
TRPS1
Illinois politician and 51st mayor of Chicago
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Harold_Washington
target promoters. CREB-binding protein, also known as CREBBP or CBP, is a protein that is encoded by the CREBBP gene in humans. The CREB protein carries
Deficiency of RbAp48 protein and memory loss
Deficiency_of_RbAp48_protein_and_memory_loss
Academic discipline focused on effects of social factors on genome activity
results in the activation of the transcription factor CREB, via the activity of β-adrenergic receptors. CREB then is able to up-regulate the transcription of
Sociogenomics
CREB-binding protein/β-catenin inhibitor
Foscenvivint (PRI 724 or OP 724) is a CREB-binding protein/β-catenin inhibitor that is developed for the treatment of liver diseases such as primary biliary
Foscenvivint
Chemical compound
scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway". Behavioural Brain Research. 253: 212–6. doi:10.1016/j.bbr.2013
Tetramethylpyrazine
Protein-coding gene in the species Homo sapiens
second messengers, and energy. SREBF1 has been shown to interact with: CREB-binding protein, DAX1 LMNA, and TWIST2. BHLHE40 BHLHE41 Sterol regulatory
Sterol regulatory element-binding protein 1
Sterol_regulatory_element-binding_protein_1
DNA-binding structural motif
cAMP-response element binding protein (CREB), and the NFIL3 protein in turn competes for binding sites shared with CREB and CCAAT/Enhancer Binding Protein
Leucine_zipper
Cognitive process
Digital media addictions Cellular mechanisms Transcriptional ΔFosB c-Fos Cdk5 CREB GluR2 NF-κB Epigenetic G9a G9a-like protein HDAC1 HDAC2 HDAC3 HDAC4 HDAC5
Motivational_salience
activation of CREB. Overall, HULC lncRNA is part of a self-amplifying autoregulatory loop in which it sponges miR-372 to activate CREB, and in turn upregulates
Competing_endogenous_RNA
Medication used for alcohol intoxication
Metadoxine may block the differentiation step of preadipocytes by inhibiting CREB phosphorylation and binding to the cAMP response element, thereby repressing
Metadoxine
Topics referred to by the same term
Park, a business park in Gunnersbury, West London Contention based protocol CREB-binding protein a protein used in human transcriptional coactivation Calcium-binding
CBP
Group of biological receptors
is activated, it phosphorylates the CREB protein (adds a high energy phosphate group) and activates it. The CREB protein binds to cAMP response elements
Opioid_receptor
Construct in psychology
demonstrated that increasing the excitability of these neurons via increased CREB expression resulted in an increased amount of time that the rats would keep
Distress_tolerance
Monoamine neurotransmitter
results in a complex relay of signals in the osteoblasts culminating in FoxO1/ Creb and ATF4 dependent transcriptional events. Following the 2008 findings that
Serotonin
Protein-coding gene in humans
alternate cleavage products of SMIM20. PNX-20 treatments increased CREB phosphylation (pCREB) and ERK1/2 phosphorylation (pERK1/2) in various cell lines. These
GPR173
Pharmacodynamics and pharmacokinetics of ethanol
protein (CREB), inducing CREB-mediated changes in gene expression. With chronic alcohol intake, consumption of ethanol similarly induces CREB phosphorylation
Pharmacology_of_ethanol
Radiograph made by recording radiation emitted by samples on photographic plates
autoradiograph of the gel. (See figure 3. of a recent study showing that CREB-binding protein is phosphorylated by HIPK2.) In plant physiology, autoradiography
Autoradiograph
Description of an addiction as a disease
their mechanisms. The common biomolecular mechanisms underlying addiction – CREB and ΔFosB – were reviewed by Eric J. Nestler in a 2013 review. Genetics and
Disease_model_of_addiction
Rare genetic condition
that helps control the activity of many other genes. The protein, called CREB-binding protein, plays an important role in regulating cell growth and division
Rubinstein–Taybi_syndrome
Aspect of learning procedure
transduction pathway are necessary for conditioning related plasticity. CREB is also necessary for conditioning related plasticity, and it may induce
Classical_conditioning
Protein-coding gene in the species Homo sapiens
transcriptional co-activator protein. EP300 is closely related to another gene, CREB binding protein, which is found on human chromosome 16. p300 HAT functions
EP300
Disorder resulting in compulsive behaviors
reward-sensitizing effect, CREB transcriptional activity decreases user's sensitivity to the rewarding effects of the substance. CREB transcription in the nucleus
Addiction
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
William Kellogg (Illinois politician)
William_Kellogg_(Illinois_politician)
American medical investigator (born 1951)
were able to show that light induced CREB phosphorylation occurs only during the subjective night. Given that CREB has been shown to regulate c-fos transcription
Joseph_Takahashi
Protein-coding gene in the species Homo sapiens
pathway positive regulation of synaptic plasticity positive regulation of CREB transcription factor activity activation of protein kinase A activity positive
ADCY8
Protein-coding gene in the species Homo sapiens
monophosphate (cAMP). GPR97 actives cAMP response element-binding protein (CREB), NF-κB, and small GTPases to regulate cellular functions. Systemic steroid
GPR97
System of signaling molecules within a cell
allosteric activation of proliferative transcription factors such as Myc and CREB. Earl Wilbur Sutherland Jr., discovered second messengers, for which he won
Second_messenger_system
American politician (born 1958)
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Mike_Quigley
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Thomas_J._Selby
Family of RNA-binding proteins
these tumors express a EWSR1-CREB1 fusion gene in most cases or a EWSR1-CREB, FUS-CREB, EWSR1-ATF1, FUS-ATF1, WSR1-CREM, or FUS-CREM fusion gene in uncommon
FET_protein_family
FOSB FOSL1 FOSL2 JDP2 c-Jun JUNB JunD BACH 1 2 BATF BLZF1 C/EBP α β γ δ ε ζ CREB 1 3 L1 CREM DBP DDIT3 GABPA GCN4 HLF MAF B sMaf F G K NFE 2 L1 L2 L3 NFIL3
GSX2
Protein-coding gene in the species Homo sapiens
Goodman RH, Korsmeyer SJ (April 2001). "MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein". Molecular and Cellular Biology
KMT2A
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Ralph_Plumb
Book by Lauren Slater
António Egas Moniz and his development of lobotomy Eric Kandel, who identified CREB as a protein involved in long-term memory B. F. Skinner's daughter Deborah
Opening_Skinner's_Box
Immune system protein
multimolecular complexes. The first AIRE partner that was identified is the CREB-binding protein (CBP) that is localized in nuclear bodies and is a co-activator
Autoimmune_regulator
American politician (born 1964)
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Marie_Newman
Nicks Stevie Nicks Celia Weston Lillian Hemmings Neil Patrick Harris Chester Creb Mare Winningham Alicia Spencer Rita Gayheart Miss. Hazel Evers Sally Keffler
List of American Horror Story cast members
List_of_American_Horror_Story_cast_members
Index of articles associated with the same name
RNA-binding protein Poly(A)-binding protein Nuclear cap-binding protein complex CREB-binding protein Calcium-binding protein Calcium-binding protein 1 S100 calcium-binding
Binding_protein
Protein-coding gene in the species Homo sapiens
knee osteoarthritis. SREBF2 has been shown to interact with INSIG1 and the CREB-binding protein. Sterol regulatory element-binding protein GRCh38: Ensembl
Sterol regulatory element–binding protein 2
Sterol_regulatory_element–binding_protein_2
Protein found in humans
regulatory component, suggesting a putative role for the transcription factor CREB and the source of BDNF's activity-dependent effects . There are multiple
Brain-derived neurotrophic factor
Brain-derived_neurotrophic_factor
Protein
system, it is linked to changes in a number of other gene products, such as CREB and sirtuins. In the body, ΔFosB regulates the commitment of mesenchymal
FOSB
United States politician (1800–1882)
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
John_Henry_(representative)
Species of sea snail
antagonists in vitro, and stimulate production of the transcription factor CREB in the brain. This marine species occurs off the Philippines and Indonesia;
Conus_parius
microRNAs, including miR-372. Expression of HULC is upregulated by CREB, there is a CREB-binding site in the promoter of HULC. miR-372 represses translation
HULC_(gene)
Inherited neurodegenerative disorder
reduced ability to produce speech and swallow foods and liquids (dysphagia). CREB-binding protein (CBP), a transcriptional coregulator, is essential for cell
Huntington's_disease
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Samuel_W._Moulton
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Joseph_P._Hoge
Protein-coding gene in the species Homo sapiens
CREB5 Identifiers Aliases CREB5, CRE-BPA, CREB-5, cAMP responsive element binding protein 5, CREBPA External IDs OMIM: 618262; MGI: 2443973; HomoloGene:
CREB5
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
John_Blake_Rice
Protein-coding gene in the species Homo sapiens
transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM". Mol. Cell. Biol. 20 (22): 8613–22. doi:10.1128/MCB.20.22.8613-8622
FHL5
Mammalian protein found in Homo sapiens
cAMP response element-binding protein (CREB). Phosphorylated CREB, together with its coactivators, p300 and CREB-binding protein (CBP) enhances the transcription
Growth hormone–releasing hormone
Growth_hormone–releasing_hormone
Nuclear receptor protein found in humans
FOSB FOSL1 FOSL2 JDP2 c-Jun JUNB JunD BACH 1 2 BATF BLZF1 C/EBP α β γ δ ε ζ CREB 1 3 L1 CREM DBP DDIT3 GABPA GCN4 HLF MAF B sMaf F G K NFE 2 L1 L2 L3 NFIL3
Peroxisome proliferator-activated receptor alpha
Peroxisome_proliferator-activated_receptor_alpha
American politician (1821–1885)
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Reuben_Ellwood
11th episode of the 4th season of American Horror Story
Running time 46 minutes Guest appearances Neil Patrick Harris as Chester Creb Angela Sarafyan as Alice Jamie Brewer as Marjorie Chrissy Metz as Barbara
Magical Thinking (American Horror Story)
Magical_Thinking_(American_Horror_Story)
Protein found in humans
It has multiple isoforms, which act either as repressors or activators. CREB family is important for in regulating transcription in response to various
CAMP responsive element modulator
CAMP_responsive_element_modulator
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Benjamin_F._Funk
American politician
McClory Crane Costello Enyart Bost 13th district W. J. Allen Kuykendall Raum Crebs McNulta Stevenson Tipton Stevenson D. Smith Springer Warner Hitt Lowden
Robert_A._Childs
CREB
CREB
CREB
CREB
Girl/Female
Indian
Sweet
Boy/Male
American, Australian, Biblical, British, Chinese, Danish, English, French, German, Hebrew, Swedish
Gift of God; God has Given
Girl/Female
Hindu, Indian
Name of Radha; To be Worshipped
Girl/Female
Hebrew Greek Latin
Flower.
Boy/Male
Arabic, Muslim
One who Implores for Help
Boy/Male
Assamese, Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Rajasthani, Telugu, Traditional
Gift of Sun
Boy/Male
Muslim
Shining, Brightness
Male
Scottish
Older form of Scottish Gaelic Seumas, SHEUMAIS means "supplanter."
Boy/Male
Arabic, Muslim
Light of the Faith
Boy/Male
Hindu, Indian, Marathi
Famous
CREB
CREB
CREB
CREB
CREB
n.
Frequency.
a.
Frequent; numerous.
a.
Marked with closely set ribs or ridges.
a.
Marked with closely set transverse furrows.