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Index of enzymes associated with the same name
A cyclase is an enzyme, almost always a lyase, that catalyzes a chemical reaction to form a cyclic compound. Important cyclase enzymes include: Adenylyl
Cyclase
Enzyme with key regulatory roles in most cells
Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase
Adenylyl_cyclase
Lyase enzyme that synthesizes cGMP from GTP
Guanylate cyclase (EC 4.6.1.2, also known as guanyl cyclase, guanylyl cyclase, or GC; systematic name GTP diphosphate-lyase (cyclizing; 3′,5′-cyclic-GMP-forming))
Guanylate_cyclase
Protein-coding gene in the species Homo sapiens
Pituitary adenylate cyclase-activating polypeptide, also known as PACAP, is a protein that in humans is encoded by the ADCYAP1 gene. PACAP is similar
Pituitary adenylate cyclase-activating peptide
Pituitary_adenylate_cyclase-activating_peptide
Guanylate cyclase 2C, also known as guanylyl cyclase C (GC-C), intestinal guanylate cyclase, guanylate cyclase-C receptor, or the heat-stable enterotoxin
Guanylate_cyclase_2C
Topics referred to by the same term
Sesquiterpene cyclase may refer to: Delta-cadinene synthase, an enzyme Aristolochene synthase, an enzyme Trichodiene synthase, an enzyme This disambiguation
Sesquiterpene_cyclase
Class of enzymes
Drimenol cyclase (EC 3.1.7.7, farnesyl pyrophosphate:drimenol cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase
Drimenol_cyclase
Class of enzymes
Sclareol cyclase (EC 3.1.7.4, geranylgeranyl pyrophosphate:sclareol cyclase, geranylgeranyl pyrophosphate-sclareol cyclase, GGPP:sclareol cyclase) is an
Sclareol_cyclase
Class of proteins
Photoactivated adenylyl cyclase (PAC) is a protein consisting of an adenylyl cyclase enzyme domain directly linked to a BLUF (blue light receptor using
Photoactivated adenylyl cyclase
Photoactivated_adenylyl_cyclase
Protein-coding gene in the species Homo sapiens
Guanylate cyclase activator 2B is a protein that in humans is encoded by the GUCA2B gene. This gene encodes a preproprotein that is proteolytically processed
Guanylate cyclase activator 2B
Guanylate_cyclase_activator_2B
Enzyme is involved in vasodilation
Soluble guanylyl cyclase (sGC) is one of the gasoreceptors for nitric oxide, NO. It is soluble, i.e. completely intracellular. Most notably, this enzyme
Soluble_guanylyl_cyclase
Protein-coding gene in the species Homo sapiens
Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene. This
ADCYAP1R1
Class of enzymes
1,8-Cineole synthase (EC 4.2.3.108, 1,8-cineole cyclase, geranyl pyrophoshate:1,8-cineole cyclase, 1,8-cineole synthetase) is an enzyme with systematic
1,8-cineole_synthase
Squalene-hopene cyclase (SHC) (EC 5.4.99.17) or hopan-22-ol hydro-lyase is an enzyme in the terpene cyclase/mutase family. It catalyzes the interconversion
Squalene-hopene_cyclase
Toxin produced by bacteria
Adenylate cyclase toxin is a virulence factor produced by some members of the genus Bordetella. Together with the pertussis toxin it is the most important
Adenylate_cyclase_toxin
Enzyme
(+)-β-Pinene synthase (EC 4.2.3.122, (+)-pinene cyclase, cyclase III) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [(+)-β-pinene-forming]
(+)-beta-pinene_synthase
Oxidosqualene cyclases (OSC) are enzymes involved in cyclization reactions of 2,3-oxidosqualene to form sterols or triterpenes. There are two major groups
Oxidosqualene_cyclase
DNA binding protein
Diadenylate cyclase EC 2.7.7.85, DNA integrity scanning protein DisA is a DNA binding protein participates in a DNA-damage check-point. DisA forms globular
Diadenylate_cyclase
Regulatory cytosolic enzyme
Soluble adenylyl cyclase (sAC) is a regulatory cytosolic enzyme present in almost every cell. sAC is a source of cyclic adenosine 3',5' monophosphate
Soluble_adenylyl_cyclase
Squalene—hopanol cyclase (EC 4.2.1.129, squalene—hopene cyclase) is an enzyme with systematic name hopan-22-ol hydro-lyase. This enzyme catalyses the following
Squalene—-hopanol_cyclase
In enzymology, diguanylate cyclase, also known as diguanylate kinase (EC 2.7.7.65), is an enzyme that catalyzes the chemical reaction: 2 Guanosine triphosphate
Diguanylate_cyclase
Cellular second messenger
activation of adenylyl cyclase stimulatory G (Gs)-protein-coupled receptors. Adenylyl cyclase is inhibited by agonists of adenylyl cyclase inhibitory G (Gi)-protein-coupled
Cyclic adenosine monophosphate
Cyclic_adenosine_monophosphate
Signal cascade used for cell to cell communication
molecular biology, the cAMP-dependent pathway, also known as the adenylyl cyclase pathway, is a G protein-coupled receptor-triggered signaling cascade used
CAMP-dependent_pathway
Mammalian protein found in Homo sapiens
protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsα is a GTPase that functions as a cellular signaling protein. Gsα is
Gs_alpha_subunit
Chemical compound
research to increase levels of cyclic AMP by stimulation of adenylate cyclase. The name comes from an obsolete name for the plant, Plectranthus forskolaei
Forskolin
Class of drugs
C, and activation of α2 inhibits the enzyme adenylate cyclase. Inactivation of adenylate cyclase in turn leads to the inactivation of the secondary messenger
Alpha-adrenergic_agonist
Protein family
6-phosphate cycloaldolase, inositol 1-phosphate synthatase, glucose 6-phosphate cyclase, inositol 1-phosphate synthetase, glucose-6-phosphate inositol monophosphate
Inositol-3-phosphate_synthase
Lycopene β-cyclase (EC 5.5.1.19, CrtL, CrtL-b, CrtY) is an enzyme with systematic name carotenoid beta-end group lyase (decyclizing). This enzyme catalyses
Lycopene_beta-cyclase
names in common use include glutaminyl-tRNA cyclotransferase, glutaminyl cyclase, and glutaminyl-transfer ribonucleate cyclotransferase. As of late 2007
Glutaminyl-peptide cyclotransferase
Glutaminyl-peptide_cyclotransferase
Protein family
In molecular biology, the cyclase-associated protein family (CAP) is a family of highly conserved actin-binding proteins present in a wide range of organisms
Cyclase-associated protein family
Cyclase-associated_protein_family
Chemical compound
cyclase (pGC) receptor, and nitric oxide (NO), identified as the endothelium-derived relaxing factor, was shown to activate soluble guanylyl cyclase (sGC)
Cyclic guanosine monophosphate
Cyclic_guanosine_monophosphate
Member of a group of proteins that upregulate guanylate cyclase
guanylate cyclase activator (or "GUCA") is a member of a group of proteins that upregulate guanylate cyclase. GUCA is also known as guanylate cyclase-activating
Guanylate_cyclase_activator
Class of pharmaceutical drugs
Soluble guanylate cyclase (sGC) stimulators are a class of drugs developed to treat heart failure, pulmonary hypertension, and other diseases. The first-in-class
Soluble guanylate cyclase stimulator
Soluble_guanylate_cyclase_stimulator
Class of enzymes
(+)-α-pinene synthase (EC 4.2.3.121, (+)-α-pinene cyclase, cyclase I) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [cyclizing
(+)-alpha-pinene_synthase
Protein-coding gene in the species Homo sapiens
Guanylyl cyclase-activating protein 2 is an enzyme that in humans is encoded by the GUCA1B gene. Alternative names: Guanylate cyclase activator 1B Retinal
GUCA1B
Enzyme
In enzymology, a ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (EC 3.2.2.6) is a bifunctional enzyme that catalyzes the chemical reaction NAD+ + H2O
ADP-ribosyl_cyclase
Class of enzymes
synthase (EC 4.2.3.119, (−)-α-pinene/(−)-camphene synthase, (−)-α-pinene cyclase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase
(−)-alpha-pinene_synthase
Peptide hormone
specifically activates the next enzyme in the cascade, adenylate cyclase. Adenylate cyclase manufactures cyclic adenosine monophosphate (cyclic AMP or cAMP)
Glucagon
In enzymology, an allene-oxide cyclase (EC 5.3.99.6) is an enzyme that belongs to the family of isomerases, specifically a class of other intramolecular
Allene_oxide_cyclase
Protein-coding gene in the species Homo sapiens
Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an atrial natriuretic peptide receptor
NPR1
Chemical compound
Avenciguat (development name BI 685509) is a soluble guanylate cyclase activator developed by Boehringer Ingelheim for kidney disease, and cirrhosis.
Avenciguat
Index of enzymes associated with the same name
Farnesyl pyrophosphate cyclase may refer to the following enzymes: 5-epiaristolochene synthase (+)-epicubenol synthase This set index page lists enzyme
Farnesyl pyrophosphate cyclase
Farnesyl_pyrophosphate_cyclase
(gene)) is an enzyme with systematic name tetraprenyl-β-curcumene—sporulenol cyclase. This enzyme catalyses the following chemical reaction sporulenol ⇌ {\displaystyle
Sporulenol_synthase
Pharmaceutical compound
research which acts as a selective antagonist of the pituitary adenylate cyclase-activating polypeptide type I receptor (PAC1). In animal studies it has
PA-915
Protein-coding gene in the species Homo sapiens
Retinal guanylyl cyclase 1 also known as guanylate cyclase 2D, retinal is an enzyme that in humans is encoded by the GUCY2D (guanylate cyclase 2D) gene. This
GUCY2D
Protein family
farnesyltransferases is responsible for peptide binding. Squalene-hopene cyclase is a bacterial enzyme that catalyzes the cyclization of squalene into hopene
Prenyltransferase
In enzymology, a RNA-3′-phosphate cyclase (EC 6.5.1.4) is an enzyme that catalyzes the chemical reaction ATP + RNA 3'-terminal-phosphate ⇌ {\displaystyle
RNA-3'-phosphate_cyclase
Pharmaceutical drug
Div, MSN Laboratories, India). Plecanatide is an agonist of guanylate cyclase-C. Plecanatide increases intestinal transit and fluid through a buildup
Plecanatide
Experimental drug
(development code MK-5475) is an experimental inhaled soluble guanylate cyclase stimulator developed by Merck for pulmonary arterial hypertension. Bajwa
Frespaciguat
Class of enzymes
adenylyl cyclase. The alpha subunit of a stimulatory G protein activated by receptors for stimulatory hormones could stimulate adenylyl cyclase, which activates
Heterotrimeric_G_protein
Lycopene ε-cyclase (EC 5.5.1.18, CrtL-e, LCYe) is an enzyme with systematic name carotenoid psi-end group lyase (decyclizing). This enzyme catalyses the
Lycopene_epsilon-cyclase
Chemical compound
Adempas, is a medication by Bayer that is a stimulator of soluble guanylyl cyclase (sGC). It is used to treat two forms of pulmonary hypertension (PH): chronic
Riociguat
Enzyme
β-amyrin synthase (EC 5.4.99.39, 2,3-oxidosqualene beta-amyrin cyclase, AsbAS1, BPY, EtAS, GgbAS1, LjAMY1, MtAMY1, PNY, BgbAS) is an enzyme with systematic
Beta-amyrin_synthase
American pharmacologist (1941–2015)
the cell surface. Cyclic AMP is formed from ATP by the enzymes adenylyl cyclase. In 1970 Martin Rodbell found that hormones did not directly influence
Alfred_G._Gilman
Protein family
cyclase-coupled receptors, receptor guanylate cyclases or membrane-bound guanylyl cyclases are single-pass transmembrane proteins. Guanylate cyclase-coupled
Guanylate cyclase-coupled receptor
Guanylate_cyclase-coupled_receptor
Class of enzymes
Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (EC 1.14.13.81), is an enzyme with systematic name magnesium-protoporphyrin-IX 13-monomethyl
Magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
Magnesium-protoporphyrin_IX_monomethyl_ester_(oxidative)_cyclase
Topics referred to by the same term
Capoeira Angola Pelourinho, Capoeira group by Mestre Moraes Guanylate cyclase-activating protein Vancouver's greenest city action plan, an urban sustainability
GCAP
Protein-coding gene in the species Homo sapiens
Adenylyl cyclase-associated protein 2 is an enzyme that in humans is encoded by the CAP2 gene. This gene was identified by its similarity to the gene
CAP2
Protein-coding gene in the species Homo sapiens
Adenylyl cyclase type 8 is an enzyme that in humans is encoded by the ADCY8 gene. Adenylyl cyclase is a membrane bound enzyme that catalyses the formation
ADCY8
Class of enzymes
(EC 4.2.3.62, (2Z,6E)-farnesyl diphosphate cyclizing) ((−)-γ-cadinene cyclase) is an enzyme with the systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase
(−)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)
(−)-gamma-cadinene_synthase_((2Z,6E)-farnesyl_diphosphate_cyclizing)
Chemical compound
Bithionol has been shown to be a potent inhibitor of soluble adenylyl cyclase, an intracellular enzyme important in the catalysis of adenosine triphosphate
Bithionol
Protein-coding gene in the species Homo sapiens
Guanylate cyclase soluble subunit alpha-2 is an enzyme that in humans is encoded by the GUCY1A2 gene. GRCh38: Ensembl release 89: ENSG00000152402 – Ensembl
GUCY1A2
Protein-coding gene in the species Homo sapiens
Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase class-3
ADCY2
Enzyme
Olivetolic acid cyclase (EC 4.4.1.26, OAC) is an enzyme with systematic name 3,5,7-trioxododecanoyl-CoA CoA-lyase (2,4-dihydroxy-6-pentylbenzoate-forming)
Olivetolic_acid_cyclase
Family of proteins
In molecular biology, the polyketide synthesis cyclase family of proteins includes a number of cyclases involved in polyketide synthesis in a number of
Polyketide synthesis cyclase family
Polyketide_synthesis_cyclase_family
Enzyme
β-Selinene cyclase (EC 4.2.3.66) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (β-selinene-forming). This enzyme catalyses
Beta-selinene_cyclase
InterPro Family
proteins primarily inhibit the cAMP dependent pathway by inhibiting adenylyl cyclase activity, resulting in decreased activity of cAMP-dependent protein kinase
Gi_alpha_subunit
The enzyme cytidylate cyclase (EC 4.6.1.6) is an enzyme that catalyzes the reaction CTP = 3′,5′-cyclic CMP + diphosphate This enzyme belongs to the family
Cytidylate_cyclase
Enzyme
adenylate cyclase is an adenylate cyclase produced by Bordetella pertussis. Kessin RH, Franke J (April 1986). "Secreted adenylate cyclase of Bordetella
Extracellular adenylate cyclase
Extracellular_adenylate_cyclase
Increased blood pressure in lung arteries
platelets), where it increases the activity of the enzyme soluble guanylate cyclase, leading to increased formation of cyclic guanosine monophosphate (cGMP)
Pulmonary_hypertension
Chemical compound
Runcaciguat is a soluble guanylate cyclase activator developed by Bayer for non-proliferative diabetic retinopathy and chronic kidney disease. Bénardeau
Runcaciguat
Mammalian protein found in humans
(adrenaline), a hormone and neurotransmitter whose signaling, via adenylate cyclase stimulation through trimeric Gs proteins, increases cAMP, and, via downstream
Beta-2_adrenergic_receptor
Gene of the species Homo sapiens
Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. The protein encoded by this gene is related to the Saccharomyces
CAP1
Chemical compound
produced from nicotinamide adenine dinucleotide (NAD+) by ADP-ribosyl cyclases (EC 3.2.2.5) as part of a second messenger system. cADPR is a cellular
Cyclic_ADP-ribose
American chemist and Nobel Laureate (born 1941)
(1968). Studies of the mechanism of action of 2,3-oxidosqualene-lanosterol cyclase: featuring enzymic cyclization of modified squalene oxides (Ph.D.). Stanford
Karl_Barry_Sharpless
Class of enzymes
(+)-Car-3-ene synthase (EC 4.2.3.107, 3-carene cyclase, 3-carene synthase, 3CAR, (+)-3-carene synthase) is an enzyme with systematic name geranyl-diphosphate
(+)-car-3-ene_synthase
Protein-coding gene in the species Homo sapiens
encoded by the QPCT gene. This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many
QPCT
Enzyme
diphosphate ⇌ {\displaystyle \rightleftharpoons } (−)-β-pinene + diphosphate Cyclase II of Salvia officinalis (sage) produces about equal parts (−)-α-pinene
(−)-beta-pinene_synthase
Protein-coding gene in the species Homo sapiens
Adenylyl cyclase type 9 is an enzyme that in humans is encoded by the ADCY9 gene. Adenylyl cyclase is a membrane bound enzyme that catalyses the formation
ADCY9
Protein-coding gene in the species Homo sapiens
Adenylyl cyclase type 5 is an enzyme that in humans is encoded by the ADCY5 gene. The human ADCY5 gene is located on the long arm of chromosome 3 and
ADCY5
Chemical compound
monooxygenase. 2,3-Oxidosqualene is the substrate of various oxidosqualene cyclases, including lanosterol synthase, which produces lanosterol, a precursor
2,3-Oxidosqualene
Medications that relax muscles of the airways
affinity. The activation of β1, β2 and β3 activates the enzyme, adenylate cyclase. This, in turn, leads to the activation of the secondary messenger cyclic
Beta-adrenergic_agonist
Chemical compound
treatment of cough in acute respiratory infection. It is a glutaminyl cyclase inhibitor. "Histamine glutarimide - EURRUS Biotech". AdisInsight. Springer
Histamine_glutarimide
Class of enzymes
names in common use include (−)-endo-fenchol cyclase, and geranyl pyrophosphate:(−)-endo-fenchol cyclase. This enzyme participates in monoterpenoid biosynthesis
(−)-endo-fenchol_synthase
Peptide hormone that regulates the endocrine system
parietal cells via a G-protein coupled receptor (which inhibits adenylate cyclase, thus effectively antagonising the stimulatory effect of histamine) to
Somatostatin
Phosphoribosylformylglycinamidine cyclo-ligase (AIR synthetase) is the fifth enzyme (EC 6.3.3.1) in the de novo synthesis of purine nucleotides. It catalyzes
AIR_synthetase_(FGAM_cyclase)
Protein-coding gene in humans
Retinal guanylyl cyclase 2 also known as guanylate cyclase F (GUCY2F) is a protein that in humans is encoded by the GUCY2F gene. The protein encoded by
GUCY2F
Receptor for atrial natriuretic peptide
receptor for atrial natriuretic peptide. NPRA and NPRB are linked to guanylyl cyclases, while NPRC is G-protein-linked and is a "clearance receptor" that acts
Atrial natriuretic peptide receptor
Atrial_natriuretic_peptide_receptor
Mammalian protein found in Homo sapiens
of humans and other animals. They are positively coupled to adenylate cyclase via Gs alpha subunit. It is a potent stimulant of cAMP production, which
Histamine_H2_receptor
Protein-coding gene in humans
Adenylyl cyclase type 6 is an enzyme that in humans is encoded by the ADCY6 gene. This gene encodes adenylyl cyclase 6, which is a membrane-associated
ADCY6
System of signaling molecules within a cell
systems can be synthesized and activated by enzymes, for example, the cyclases that synthesize cyclic nucleotides, or by opening of ion channels to allow
Second_messenger_system
Protein-coding gene in the species Homo sapiens
that is a key component of G protein-coupled receptor-regulated adenylyl cyclase signal transduction pathways in the olfactory system and the striatum in
GNAL
Protein-coding gene in the species Homo sapiens
Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene. Soluble guanylate cyclase (sGC), a heterodimeric protein
GUCY1B3
Egg cell production process
cyclic AMP is generated by the oocyte by adenylyl cyclase in the oocyte membrane. The adenylyl cyclase is kept active by a constitutively active G protein-coupled
Oogenesis
Class of opioid receptors found in humans
coupled receptor that activates the Gi alpha subunit, inhibiting adenylate cyclase activity, lowering cAMP levels. The structure of the inactive μ-opioid
Mu-opioid_receptor
Protein-coding gene in the species Homo sapiens
Adenylyl cyclase type 7 is an enzyme that in humans is encoded by the ADCY7 gene. This gene encodes a membrane-bound adenylyl cyclase that catalyses the
ADCY7
Gene locus
Gs-α, a key component of G protein-coupled receptor-regulated adenylyl cyclase signal transduction pathways. GNAS stands for Guanine Nucleotide binding
GNAS_complex_locus
Class of chemical compounds
bacterial genomes have a putative shc gene encoding a squalene-hopene cyclase and can presumably make hopanoids, which have been shown to play diverse
Hopanoids
Respiratory toxin
Adenylate cyclase toxin (CyaA) is released from bacterium Bordetella pertussis by the T1SS (Type 1 secretion system) and released in the host's respiratory
CyaA
Human protein-coding gene
known as atrionatriuretic peptide receptor B and formerly as guanylate cyclase B, is an atrial natriuretic peptide receptor which in humans is encoded
NPR2
CYCLASE
CYCLASE
CYCLASE
CYCLASE
Boy/Male
British, English, Hindu, Indian, Malayalam, Marathi
Lord Surya (Sun); Illuminate; Light Up
Girl/Female
Danish, Finnish, German
Gaze; Looking
Boy/Male
Arabic, Muslim
Servant of the Expander
Girl/Female
Arabic, Muslim
Happy
Girl/Female
Sikh
A vow to a deity, Wish
Male
French
 French form of Greek BeniamÃn from Hebrew Binyamin, BENJAMIN means "son of the right hand." Compare with another form of Benjamin.
Girl/Female
Hindu
Surname or Lastname
English
English : perhaps a variant of Carrington or a habitational name from some other place now lost. See also Currington.
Girl/Female
Indian
Name of a river
Boy/Male
Arabic
The Biblical Enoch is the English Language Equivalent
CYCLASE
CYCLASE
CYCLASE
CYCLASE
CYCLASE