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NPR2

  • NPR2
  • Human protein-coding gene

    Natriuretic peptide receptor B (NPR2), also known as atrionatriuretic peptide receptor B and formerly as guanylate cyclase B, is an atrial natriuretic

    NPR2

    NPR2

    NPR2

  • Dwarfism
  • Small size of an organism, caused by growth deficiency or genetic mutations

    Hypogonadotropic hypogonadism may cause proportionate, yet temporary, dwarfism. NPR2 disproportionate dwarfism was discovered recently and is caused by a mutant

    Dwarfism

    Dwarfism

    Dwarfism

  • Meiosis
  • Cell division producing haploid gametes

    5′-monophosphate (cGMP) in concert with natriuretic peptide receptor 2 (NPR2) on cumulus cells. cGMP diffuses into oocytes and halts meiosis by inhibiting

    Meiosis

    Meiosis

    Meiosis

  • Acromesomelic dysplasia
  • Medical condition

    a protein that affects bone development, natriuretic peptide receptor B (Npr2). This is a receptor for the hormone C-type natriuretic peptide which is

    Acromesomelic dysplasia

    Acromesomelic_dysplasia

  • Selective serotonin reuptake inhibitor
  • Class of antidepressant medication

    attitudes". Neuropsychopharmacology Reports. 44 (2): 321–332. doi:10.1002/npr2.12417. PMC 11144621. PMID 38616339. Costagliola C, Parmeggiani F, Semeraro

    Selective serotonin reuptake inhibitor

    Selective serotonin reuptake inhibitor

    Selective_serotonin_reuptake_inhibitor

  • Aripiprazole
  • Atypical antipsychotic medication

    brexpiprazole". Neuropsychopharmacology Reports. 41 (2): 134–143. doi:10.1002/npr2.12180. PMC 8340839. PMID 33960741. Kikuchi T, Tottori K, Uwahodo Y, Hirose

    Aripiprazole

    Aripiprazole

    Aripiprazole

  • Brexpiprazole
  • Serotonin dopamine partial agonist atypical antipsychotic

    brexpiprazole". Neuropsychopharmacology Reports. 41 (2): 134–143. doi:10.1002/npr2.12180. PMC 8340839. PMID 33960741. Rege S (23 October 2020). "Aripiprazole

    Brexpiprazole

    Brexpiprazole

    Brexpiprazole

  • Lemborexant
  • Chemical compound

    A review". Neuropsychopharmacology Reports. 41 (4): 450–458. doi:10.1002/npr2.12205. PMC 8698673. PMID 34553844. "Lemborexant". Specialist Pharmacy Service

    Lemborexant

    Lemborexant

    Lemborexant

  • Oogenesis
  • Egg cell production process

    maintains meiotic arrest. The cyclic GMP is produced by the guanylyl cyclase NPR2. As follicles grow, they acquire receptors for luteinizing hormone, a pituitary

    Oogenesis

    Oogenesis

    Oogenesis

  • Atomoxetine
  • Medication used to treat ADHD

    Systematic Review". Neuropsychopharmacol Rep. 45 (1) e12519. doi:10.1002/npr2.12519. PMC 11713126. PMID 39783764. Ghanean H, Ceniti AK, Kennedy SH (January

    Atomoxetine

    Atomoxetine

    Atomoxetine

  • Riluzole
  • Medication used to treat amyotrophic lateral sclerosis

    systematic review". Neuropsychopharmacology Reports. 43 (3): 320–327. doi:10.1002/npr2.12364. PMC 10496048. PMID 37463744. Grant P, Song JY, Swedo SE (August 2010)

    Riluzole

    Riluzole

    Riluzole

  • Enzyme-linked receptor
  • Class of enzymes

    receptor) NPR1 NPR1 guanylyl cyclase EC 4.6.1.2 Atrial natriuretic peptide NPR2 NPR2 " C-type natriuretic peptide NPR3 NPR3 " Atrial natriuretic peptide NPR4

    Enzyme-linked receptor

    Enzyme-linked_receptor

  • Lurasidone
  • Atypical antipsychotic medication

    case report". Neuropsychopharmacology Reports. 42 (3): 377–379. doi:10.1002/npr2.12259. PMC 9515717. PMID 35609885. British national formulary: BNF 76 (76 ed

    Lurasidone

    Lurasidone

    Lurasidone

  • 5-MeO-DiPT
  • Psychedelic tryptamine

    prefrontal cortex". Neuropsychopharmacol Rep. 41 (1): 91–101. doi:10.1002/npr2.12161. PMC 8182963. PMID 33547882. Sogawa C, Sogawa N, Tagawa J, Fujino A

    5-MeO-DiPT

    5-MeO-DiPT

    5-MeO-DiPT

  • Suvorexant
  • Medication used to treat insomnia

    antagonists: A review". Neuropsychopharmacol Rep. 41 (4): 450–458. doi:10.1002/npr2.12205. PMC 8698673. PMID 34553844. Uchiyama M, Kambe D, Imadera Y, Kajiyama

    Suvorexant

    Suvorexant

    Suvorexant

  • Depressant
  • Drugs that lower neurotransmission levels, reducing brain activity

    literature review". Neuropsychopharmacology Reports. 41 (3): 434–439. doi:10.1002/npr2.12195. PMC 8411313. PMID 34382380. Hellwig, Thaddaus R.; Hammerquist, Rhonda;

    Depressant

    Depressant

    Depressant

  • Atrial natriuretic peptide receptor
  • Receptor for atrial natriuretic peptide

    guanylate cyclase B (atrionatriuretic peptide receptor B) Identifiers Symbol NPR2 Alt. symbols ANPRB, NPRB NCBI gene 4882 HGNC 7944 OMIM 108961 RefSeq NM_003995

    Atrial natriuretic peptide receptor

    Atrial_natriuretic_peptide_receptor

  • Mood stabilizer
  • Psychiatric medication used to treat mood disorders

    Antiseizure Drugs". Neuropsychopharmacology Reports. 41 (3): 336–351. doi:10.1002/npr2.12196. ISSN 2574-173X. PMC 8411307. PMID 34296824. Crapanzano, Calogero;

    Mood stabilizer

    Mood stabilizer

    Mood_stabilizer

  • Transition metal pincer complex
  • derived from long-chain ditertiary phosphines, species of the type R2P(CH2)nPR2 where n >4 and R = tert-butyl. Platinum metalates one methylene group with

    Transition metal pincer complex

    Transition metal pincer complex

    Transition_metal_pincer_complex

  • List of investigational long COVID drugs
  • Investigational long COVID drugs

    cognitive impairment". Neuropsychopharmacol Rep. 44 (3): 585–590. doi:10.1002/npr2.12466. PMC 11544435. PMID 38934345. Fujimoto Y, Abe H, Eiro T, Tsugawa S

    List of investigational long COVID drugs

    List_of_investigational_long_COVID_drugs

  • Tonotopy
  • Arrangement of sound frequency processing in the brain

    specific frequencies. Research has suggested that the receptor guanylyl cyclase Npr2 is vital for the precise and specific organization of this tonotopy. Further

    Tonotopy

    Tonotopy

  • Guanylate cyclase-coupled receptor
  • Protein family

    An example of Guanylate cyclase-coupled receptors is ANF receptors (NPR1, NPR2 and NPR3) in kidney. Additionally, there exist intracellular guanylate cyclase-coupled

    Guanylate cyclase-coupled receptor

    Guanylate_cyclase-coupled_receptor

  • Little Women: Atlanta
  • Reality television series about women with dwarfism

    group: the fact that she has a rare form of dwarfism related to a mutant NPR2 gene. And the girls wig out as they take the runway at Atlanta's premiere

    Little Women: Atlanta

    Little_Women:_Atlanta

  • List of OMIM disorder codes
  • Hunter-Thompson type; 201250; GDF5 Acromesomelic dysplasia, Maroteaux type; 602875; NPR2 Action myoclonus-renal failure syndrome; 254900; SCARB2 Acyl-CoA dehydrogenase

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

  • Cyclase
  • Index of enzymes associated with the same name

    GUCY1B3 Guanylate cyclase 2C Guanylate cyclase 2D Guanylate cyclase 2F NPR1 NPR2 Protein cyclase, a ligase enzyme that produces backbone-cyclised proteins

    Cyclase

    Cyclase

  • Resumption of meiosis
  • present the granulosa cells, in particular, natriuretic peptide receptor 2 (NPR2) and natriuretic peptide precursor-C (NPPC) that can be found in the cumulus

    Resumption of meiosis

    Resumption_of_meiosis

  • Atrial natriuretic peptide
  • Cardiac hormone which increases renal sodium excretion

    cyclase-B (GC-B) also known as natriuretic peptide receptor-B (NPRB/ANPB) or NPR2 natriuretic peptide clearance receptor (NPRC/ANPC) or NPR3 NPR-A and NPR-B

    Atrial natriuretic peptide

    Atrial natriuretic peptide

    Atrial_natriuretic_peptide

  • List of investigational social anxiety disorder drugs
  • and meta-analysis". Neuropsychopharmacol Rep. 42 (4): 398–409. doi:10.1002/npr2.12275. PMC 9773641. PMID 35848723. Brady LS, Lisanby SH, Gordon JA (2023)

    List of investigational social anxiety disorder drugs

    List_of_investigational_social_anxiety_disorder_drugs

  • DEPDC5
  • Protein-coding gene in the species Homo sapiens

    to aid in binding to two protein partners, Npr2 and Npr3. Together, these three proteins form the Iml1-Npr2-Npr3 complex and are involved in "non-nitrogen

    DEPDC5

    DEPDC5

    DEPDC5

  • Organophosphine
  • Class of chemical compounds

    closes a ring: R2PH + R'2C=O → R2PC(OH)HR'2 Diphosphines, R2PPR2, R2P(CH2)nPR2 Phosphine oxide, R3P=O Phosphorane, PR5, R3P=CR2 Phosphinite, P(OR)R2 Phosphonite

    Organophosphine

    Organophosphine

  • List of investigational fatigue drugs
  • Investigational fatigue drugs

    Systematic Review". Neuropsychopharmacol Rep. 45 (1) e12519. doi:10.1002/npr2.12519. PMC 11713126. PMID 39783764. Hagan AJ, Kumar R (2023). "The Utility

    List of investigational fatigue drugs

    List_of_investigational_fatigue_drugs

  • Laurinda Jaffe
  • American biologist

    growth. Hormonal signalling decreases the amount of cGMP by inactivating NPR2. In the ovaries, this causes the cGMP to resume meiotic function, whilst

    Laurinda Jaffe

    Laurinda_Jaffe

  • Antipsychotic abuse
  • Harmful use of antipsychotic medications

    retrospective study". Neuropsychopharmacology Reports. 43 (3): 434–439. doi:10.1002/npr2.12372. ISSN 2574-173X. PMC 10496068. PMID 37574802. Merino, Diane; Gérard

    Antipsychotic abuse

    Antipsychotic_abuse

  • Protein kinase domain
  • Protein domain

    NEK2 ; NEK3 ; NEK4 ; NEK5 ; NEK6 ; NEK7 ; NEK8 ; NEK9 ; NIM1K ; NLK ; NPR1 ; NPR2 ; NRBP1 ; NRBP2 ; NRK ; NTRK1 ; NTRK2 ; NTRK3 ; NUAK1 ; NUAK2 ; OBSCN ; OXSR1 ;

    Protein kinase domain

    Protein kinase domain

    Protein_kinase_domain

  • NPR3
  • Protein-coding gene in humans

    1035–43. doi:10.1016/j.peptides.2004.08.035. PMID 15911071. S2CID 28281513. NPR2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings

    NPR3

    NPR3

    NPR3

  • NPRL2
  • Protein-coding gene in the species Homo sapiens

    NPRL2 Identifiers Aliases NPRL2, NPR2, NPR2L, TUSC4, NPR2-like, GATOR1 complex subunit, FFEVF2, NPR2 like, GATOR1 complex subunit External IDs OMIM: 607072;

    NPRL2

    NPRL2

    NPRL2

  • List of human protein-coding genes 5
  • HGNC:7940; P16860 10747 NPPC HGNC:7941; P23582 10748 NPR1 HGNC:7943; P16066 10749 NPR2 HGNC:7944; P20594 10750 NPR3 HGNC:7945; P17342 10751 NPRL2 HGNC:24969; Q8WTW4

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

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NPR2

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NPR2