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Highly ordered, branched polymeric molecule
Dendrimers are highly ordered, branched polymeric molecules. Synonymous terms for dendrimer include arborols and cascade molecules. Typically, dendrimers
Dendrimer
Dendrimer-encapsulated nanoparticles (DENs) are nanoparticles ranging from 1.5 to 10 nm that are synthesized by a template approach using dendrimers. Monometallic
Dendrimer-encapsulated nanoparticles
Dendrimer-encapsulated_nanoparticles
Formation of a thioether (–S–) compound from a thiol (–SH) and an alkene ( >C=C< )
glycodendrons, polythioether dendrimers and organosilicon thioether dendrimers. A general strategy for the divergent synthesis of a dendrimer begins with a core;
Thiol-ene_reaction
Range 300-3000 GHz of the electromagnetic spectrum
diodes have been shown to operate up to 1.98 THz. To the right, image of Dendrimer Dipole Excitation (DDE) Mechanism for broadband 30THz emitter used for
Terahertz_radiation
Class of polymeric molecules
PAMAM, is a class of dendrimer which is made of repetitively branched subunits of amide and amine functionality. PAMAM dendrimers, sometimes referred to
Poly(amidoamine)
Ferrocene-containing dendrimers are dendrimers that contain ferrocene substituents. Some ferrocene-containing dendrimers feature ferrocene cores and others
Ferrocene-containing dendrimers
Ferrocene-containing_dendrimers
Hungarian-American scientist
is a Hungarian-American scientist known for his research on polymers, dendrimer nanocomposites, and nanomedicine. Balogh is the editor-in-chief of Precision
Lajos_Balogh_(scientist)
Materials that convert light to energy
biological systems. Examples of synthetic light harvesting materials are dendrimers, porphyrin arrays and assemblies, organic gels, biosynthetic and synthetic
Light_harvesting_materials
Largest stable synthetic molecule ever made
the largest stable synthetic molecule ever made up to 2010. PG5 is a dendrimer designed by the organic chemistry research group working at the Federal
PG5
Chemical compound
Toyoko (2008). "Synthesis and characterization of poly(ethyleneimine) dendrimers". Colloid & Polymer Science. 286 (6–7): 747–752. doi:10.1007/s00396-007-1830-6
Polyethylenimine
Indian chemist
He is known for his work on synthesis of complex carbohydrates and new dendrimers and is an elected fellow of the Indian Academy of Sciences. The Council
Narayanaswamy_Jayaraman
Technologies for targeted drug delivery
conjugation. Drug-dendrimer conjugation can elongate the half-life of drugs. Currently, dendrimer use in biological systems is limited due to dendrimer toxicity
Nanoparticle_drug_delivery
Strategy to improve chemical synthesis
still come together. Examples: Convergent synthesis is encountered in dendrimer synthesis where branches (with the number of generations preset) are connected
Convergent_synthesis
Very large molecule
synthetic macromolecules include: Thermoplastic polymers Thermoset polymers Dendrimers Vitrimers / Covalent adaptable networks (CANs) Covalent organic frameworks
Macromolecule
Short chains of 2–50 amino acids
Aromatic short peptides Biomimetic peptides Peptide amphiphiles Peptide dendrimers B-type Natriuretic Peptide (BNP) – produced in the myocardium and useful
Peptide
American chemist (born 1938)
is an American chemist who is known as one of the early discoverers of dendrimers. Tomalia earned an undergraduate degree from the University of Michigan
Donald_Tomalia
Romanian chemist
of liquid crystals with complex architecture, supramolecular dendrimers, Janus dendrimers and glycodendrimers, organic Frank-Kasper phases and quasicrystals
Virgil_Percec
Chemical reaction
reaction include macroamides, macrocyclic depsipeptides, three-component dendrimers and three-armed star branched mesogen core molecules. Passerini reaction
Passerini_reaction
Chemical structures
polymers have been synthesized, such as star-shape polymer, comb polymer and dendrimer. Selected branched topologies have been listed below: Cyclic structures
Topological_polymers
Drug delivery via inhalation
Poly(amidoamine) (PAMAM) dendrimers are the most commonly used system. A study investigated potential application of dendrimer-based formulation of haloperidol
Nose-to-brain drug delivery mechanism
Nose-to-brain_drug_delivery_mechanism
Chemical used to separate emulsions
resins Epoxy resins Polyethyleneimines Polyamines Di-epoxides Polyols dendrimer The above are usually ethoxylated (and/or propoxylated) to provide the
Demulsifier
Attachment of side chains to the backbone chain of a polymer
crosslinks. See for example thermosets or interpenetrating polymer networks. A dendrimer is a repetitively branched compound. In free radical polymerization, branching
Branching_(polymer_chemistry)
German chemist (born 1937)
Seebach is a German chemist known for his synthesis of biopolymers and dendrimers, and for his contributions to stereochemistry. He was born on 31 October
Dieter_Seebach
association of the nucleic acid with the cationic dendrimer. On reaching its destination the dendrimer-nucleic acid complex is then taken into the cell
Vectors_in_gene_therapy
Chemical reaction that produces polymers
architectures, such as linear block copolymers, comb-like, star, brush polymers, dendrimers and cross-linked networks. IUPAC definition Reversible-addition-fragmentation
Reversible addition−fragmentation chain-transfer polymerization
Reversible_addition−fragmentation_chain-transfer_polymerization
Inert medium used in drug-delivery systems
A drug carrier or drug vehicle is a substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness, and/or safety
Drug_carrier
Chemical compound
and it is therefore suitable as a starting point for the synthesis of dendrimers. Derivatives of truxene have also been used for the synthesis of liquid
Truxene
Electrically neutral group of two or more atoms
Structure and STM image of a "cyanostar" dendrimer molecule
Molecule
Chemical compound
Mitsui Chemicals. The compound is also of interest for the synthesis of dendrimers, a process that exploits the tendency of aziridines to undergo ring-opening
Propyleneimine
Ionization technique
peptides and carbohydrates) and various organic molecules (such as polymers, dendrimers and other macromolecules), which tend to be fragile and fragment when
Matrix-assisted laser desorption/ionization
Matrix-assisted_laser_desorption/ionization
German chemist
German chemist known for her research for in macromolecular chemistry, dendrimers, dyes, protein, and peptides. As of 2025, Weil holds the position of director
Tanja_Weil
Pharmacologic agents and chemical substances
The chemical structure of dendrimers is typically symmetric around the core, and often adopts a spherical three-dimensional morphology.
Microbicides for sexually transmitted infections
Microbicides_for_sexually_transmitted_infections
French chemist
French National Centre for Scientific Research. Her research considers dendrimers and heterochemistry. She was awarded the 2021 Société chimique de France
Anne-Marie_Caminade
Method of delivering medication
liposomes, lipoprotein-based drug carriers, nano-particle drug carriers, dendrimers, etc. An ideal drug delivery vehicle must be non-toxic, biocompatible
Targeted_drug_delivery
Medical technology
sonoporation, magnetofection, the use of oligonucleotides, lipoplexes, dendrimers, and inorganic nanoparticles. These therapeutics can be administered directly
Gene_therapy
Topological index of a molecule used in biochemistry
numerous biological and physicochemical properties. The Szeged index of Dendrimer Nanostar of the following figure can be calculated by S z ( T n ) = 1620
Szeged_index
Class of chemical compounds
cross-conjugated. The name dendralene is pulled together from the words dendrimer, linear and alkene. The higher dendralenes are of scientific interest
Dendralene
Iranian-American drug delivery research scientist
constructs, water-soluble polymers for targeted delivery and poly(amidoamine) dendrimers for oral delivery. Ghandehari was born in Iran. He received his B.S degree
Hamid_Ghandehari
American chemist
and electronic properties. Her group also investigates the design of dendrimer molecules for biomedical applications. Watkins obtained a bachelor's degree
Davita_Watkins
flexible chains on glucose molecules that grow similarly to synthetic dendrimers. The special structure of the phytoglycogen allows it to have low viscosity
Phytoglycogen
Numerical variational technique
extended to work on tree graphs, and has found applications in the study of dendrimers. For 2D systems with one of the dimensions much larger than the other
Density matrix renormalization group
Density_matrix_renormalization_group
A metallodendrimer is a type of dendrimer with incorporated metal atoms. The development of this type of material is actively pursued in academia. The
Metallodendrimer
as star polymers, comb polymers, brush polymers, dendronized polymers, dendrimers, Ring polymers and star-on-star polymers are possible. Complex architecture
Polymer_architecture
Established in 2005, Polymer Factory concentrates on developing well defined dendrimers and dendron based on 2,2-bis(methylol)propionic acid, where the company
Polymer_Factory_Sweden_AB
Substance composed of macromolecules with repeating structural units
polymers, polymer brushes, dendronized polymers, ladder polymers, and dendrimers. There exist also two-dimensional polymers (2DP) which are composed of
Polymer
Diode that emits light from an organic compound
reported by Tang et al.), fluorescent and phosphorescent dyes and conjugated dendrimers. Alq3 has been used as a green light emitter, electron transport material
OLED
Excessive growth of bacteria in the vagina
Sodium, also referred to as Astodrimer 1% Vaginal gel, is a polyanionic dendrimer that prevents formation of bacterial biofilms through blocking bacterial
Bacterial_vaginosis
Macrocylcic molecule
Cyanostar as the central unit of a dendrimer
Cyanostar
Aggressive type of brain cancer
using engineered nanoparticles, such as liposomes, polymeric micelles, dendrimers, metallic and magnetic particles to ferry chemotherapeutics, genes and
Glioblastoma
French chemist
Solubilization in Water of Olefin-Terminated Dendrimers, Polymers, and Gold Nanoparticles and for a Divergent Dendrimer Construction". J. Am. Chem. Soc. 130 (4):
Didier_Astruc
Chemical compound
replaced. Amines give melamine derivatives, for example in the synthesis of dendrimers: (ClCN)3 + R2NH → (R2NCN)3 + 3 HCl It reacts with hydrosulfide to give
Cyanuric_chloride
molar mass of a wide variety of polymers, including rod-like polymers and dendrimers. Several other methods of analysis are used to determine the absolute
Absolute_molar_mass
Topics referred to by the same term
cell body In biochemistry, a dendron is the reduced form of its original dendrimer This disambiguation page lists articles associated with the title Dendron
Dendron
Methods for delivering drugs to target sites
targeted sites and therapeutic effects. Tiny carriers, such as liposomes, dendrimers, and polymeric nanoparticles, can hold medication and release them at
Drug_delivery
Gene Transfer Method
Microneedle Magnetofection Chemical methods: Cationic lipids Cationic polymers Dendrimer-based vectors Polypeptide-based vectors Inorganic, polymeric, and lipid
Hydrodynamic_delivery
Type of synthetic peptide
Collagen Targeting Using Synthetic Phage Mimics: From Phage Display to Dendrimer Display". Journal of the American Chemical Society. 131 (33): 11683–11685
Collagen_hybridizing_peptide
French-American chemist
including polymer-supported chemistry, chemically amplified photoresists, dendrimers, macroporous separation media, and polymers for therapeutics. He has authored
Jean_Fréchet
Dutch organic chemist
poly(propylene imine) dendrimers that are now produced at commercially relevant quantities (at multiple kilogram scale) worldwide. His dendrimers form the basic
Bert_Meijer
Medical application of nanotechnology
Nanoparticles (top), liposomes (middle), and dendrimers (bottom) are some nanomaterials being investigated for use in nanomedicine.
Nanomedicine
Process of introducing nucleic acids into eukaryotic cells
transfecting a wide variety of cells with high efficiency and low toxicity. Dendrimer is a class of highly branched molecules based on various building blocks
Transfection
Chemical compound
(2004). "Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes". Angewandte
Propargyl_bromide
Nanosized Molecular Propellers by Cyclodehydrogenation of Polyphenylene Dendrimers Christopher D. Simpson, Gunter Mattersteig, Kai Martin, Lileta Gherghel
Scholl_reaction
Protein-coding gene in the species Homo sapiens
O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8):
TMEM50A
Cross-coupling reaction used in organic synthesis
filtration and reused up to five times, with diminished activity produced by dendrimer decomposition and not by palladium leaching being observed. These dendrimeric
Sonogashira_coupling
Nano-scale porous silica compound
Eric W; Jeftinija, Srdija & Lin, Victor S.-Y. (2004). "A Polyamidoamine Dendrimer-Capped Mesoporous Silica Nanosphere-Based Gene Transfection Reagent".
Mesoporous_silica
Russian biochemist (born 1965)
surface chemistry. His work included the development of nucleic‑acid dendrimers, contributing to early advances in nucleic‑acid microarray platforms.
Mikhail_Shchepinov
Indian academic
belonging to class PPAR-γ agonist and biguanides), drug delivery using dendrimers. Fellowship of Alexander von Humboldt Stiftung, Bonn IBM Faculty Award
Prasad_V._Bharatam
Protein-coding gene in humans
O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8):
Y-box-binding_protein_3
cyclic polymers, and macromolecules of complex topology such as star, dendrimer, and comb polymers, as well as polyelectrolytes, micellar and colloidal
Unified_scattering_function
Branch of chemistry
units is very well understood. nanoparticles, nanorods, fullerenes and dendrimers offer nanometer-sized structure and encapsulation units. Surfaces can
Supramolecular_chemistry
Chemical compound
provides applications as a hydrogen-bonded organic framework linker and as a dendrimer core. In Ermer's 1988 first application of 1,3,5,7-adamantanetetracarboxylic
1,3,5,7-Adamantanetetracarboxylic acid
1,3,5,7-Adamantanetetracarboxylic_acid
Protein-coding gene in the species Homo sapiens
Aebersold R (Aug 2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nature Methods. 2
TRIO_(gene)
Study of RNA transcripts
novel, sensitive detection system for high-density microarrays using dendrimer technology". Physiological Genomics. 3 (2): 93–9. doi:10.1152/physiolgenomics
Transcriptomics_technologies
Metal-free biologically compatible quantum dots with photoluminescence
"Fluorescent sensor for Cr(VI) based in functionalized silicon quantum dots with dendrimers". Talanta. 144: 862–867. doi:10.1016/j.talanta.2015.07.038. ISSN 1873-3573
Silicon_quantum_dot
Concentration and Size Dependence of Fifth- and Seventh-Generation PAMAM Dendrimers on Pore Formation in DMPC Bilayer". The Journal of Physical Chemistry
MARTINI
Topics referred to by the same term
a crystal that develops with a typical multi-branching tree-like form Dendrimer, a repetitively branched molecule Dendrite (matrix), a server for the
Dendrite_(disambiguation)
American professor of physiology and cell biology
Katzenellenbogen, John A; Katzenellenbogen, Benita S (2006). "Estrogen Dendrimer Conjugates that Preferentially Activate Extranuclear, Nongenomic Versus
Benita_Katzenellenbogen
delivery systems. Grinstaff synthesized novel biocompatible biodegradable dendrimers from natural metabolites as new biomaterials and drug delivery vehicles
Mark_W._Grinstaff
Protein-coding gene in the species Homo sapiens
L, Aebersold R (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8):
Plakophilin-4
Type of material
fundamental in the development of certain nanoparticle polymers such as dendrimers and fullerenes, that have been applied for drug delivery. Traditional
Smart_polymer
Exponential function of an exponential function
; Wilkins, Charles L.; Moore, Jeffrey S. (1995). "Double Exponential Dendrimer Growth". Journal of the American Chemical Society. 117 (8): 2159–2165
Double_exponential_function
Chemical compound
widely used in the production of polyurethane fibers. The PAMAM class of dendrimers are derived from ethylenediamine. The bleaching activator tetraacetylethylenediamine
Ethylenediamine
Pharmaceutical scientist
Porter collaborated with Starpharma to develop PEGylated polylysine dendrimer-based drug delivery systems, resulting in patents related to the DEP drug
Christopher_J._H._Porter
Linear polymer whose repeat units have regularly-branching side chains
to this field. They can be found in review articles. Dendrimer Polymer brush "Weihai CY Dendrimer Technology Co., Ltd". www.whcyd.com. Archived from the
Dendronized_polymer
Protein-coding gene in the species Homo sapiens
O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8):
LPXN
Cross-coupling reaction between boronic acid & an organohalide
phosphine nickel nanoparticle catalyst (G3DenP-Ni) that was made from dendrimers. Advantages and disadvantages apply to both the palladium and nickel-catalyzed
Suzuki_reaction
American chemist (born 1969)
excitation rate as compared to the corresponding classical TPA process in a dendrimer material. A subsequent publication reported 10 orders of magnitude enhancement
Theodore_Goodson_III
Polyamidoamine (PAMAM) dendrimers with amino- and carboxylic-acid external reactive shells are considered as sensing phase. These dendrimers are required to
Surface plasmon resonance microscopy
Surface_plasmon_resonance_microscopy
Chemical addition of an –SH and –C≡CH molecule
It is used in click chemistry and in polymerization, especially with dendrimers. This addition reaction is typically facilitated by a radical initiator
Thiol-yne_reaction
1995 trademark for fabrics used in waterproof clothing
Tear strength: weft minimum(g) 650 750 800 1200 1600 Impregnation of DWR Dendrimer based (until 2021 was fluorocarbon-6) Water absorption(max. %) 10 Resistance
Ventile
British chemist
Christensen, J. B.; Simberg, D.; Trohopoulos, P. N.; Moghimi, S. M. (2021). "Dendrimer end-terminal motif-dependent evasion of human complement and complement
Moein_Moghimi
Ordered chemical structure with no repeating pattern
systems. Soft quasicrystal structures have been found in supramolecular dendrimer liquids and ABC Star Polymers in 2004 and 2007. In 2009, it was found
Quasicrystal
German professor and biochemist (born 1962)
Columbia in Vancouver, Canada from 1992, focusing on carbohydrates and dendrimers, before returning to Hamburg to earn her habilitation in 1998. In 2000
Thisbe_Lindhorst
Plasmid cloning vector
Polyelectrolytes of Different Chain Topology: Cylindrical Brushes and Dendrimers". Macromolecules. 40 (22): 7998–8006. Bibcode:2007MaMol..40.7998S. doi:10
PUC19
Protein found in humans
Aebersold R (Aug 2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nature Methods. 2
BAG3
Radiation scattering technique
"Interpolyelectrolyte Complex and Coacervate Formation of Poly(glutamic acid) with a Dendrimer Studied by Light Scattering and SAXS". The Journal of Physical Chemistry
Small-angle_X-ray_scattering
polymers have been created with linear block copolymer, star, branched, dendrimer, brush, and comb architectures. Polymers of different architectures will
PH-sensitive_polymers
Collection of bound atoms or molecules
dictionary. Dendrimers Dendrimers are used as templates to synthesize nanoclusters. Gold nanoclusters embedded in poly(amidoamine) dendrimer (PAMAM) have
Nanocluster
Study of the toxicity of nanomaterials
classes of nanomaterials include polymers such as nanocellulose, and dendrimers. There are many ways that size can affect the toxicity of a nanoparticle
Nanotoxicology
Chemical compound
inhibitors--estramustine and natural podophyllotoxin conjugated PAMAM dendrimer on glioma cell proliferation". European Journal of Medicinal Chemistry
Estramustine
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