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Combination medication
Foscarbidopa/foslevodopa, sold under the brand name Vyalev among others, is a fixed-dose combination medication used for the treatment of Parkinson's
Foscarbidopa/foslevodopa
Chemical compound
Foslevodopa is a medication which acts as a prodrug for levodopa, originally invented in the 1980s but not developed for medical use at that time. It
Foslevodopa
Dopaminergic medication
inhalation, through an intestinal tube, or by administration into fat (as foslevodopa). Side effects of levodopa include nausea, the wearing-off phenomenon
Levodopa
Chemical compound
is used in a subcutaneous infusion as a fixed-dose combination with foslevodopa for the treatment of Parkinson's disease, under the brand name Vyalev
Foscarbidopa
Syndrome characterized by tremor, slowed movements, rigidity, and imbalance
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Parkinsonism
Medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Catechol-O-methyltransferase inhibitor
Catechol-O-methyltransferase_inhibitor
Investigational Parkinson's disease drugs
inhibitor) and levodopa (dopamine precursor) [324] Foscarbidopa/foslevodopa (ABBV-951; foslevodopa/foscarbidopa; levodopa/carbidopa prodrug; Produodopa; Vyalev)
List of investigational Parkinson's disease drugs
List_of_investigational_Parkinson's_disease_drugs
Medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Tavapadon
American pharmaceutical company
drug candidates for Parkinson's disease including Vyalev (Foscarbidopa/foslevodopa) and tavapadon. AbbVie has been accused of using anti-competitive patent
AbbVie
Drug used to treat influenzavirus A infection
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Rimantadine
Dopamine agonist medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Pramipexole
Antihistamine medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Diphenhydramine
Dopaminergic agent
amide is hydrolyzed back to the acid by aminopeptidase enzymes. DA-Phen Foslevodopa Melevodopa Etilevodopa O,O′-Diacetyldopamine O,O′-Dipivaloyldopamine
DopAmide
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Tigloidine
Parkinson's disease medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Carbidopa/levodopa
Parasympathetic nervous system inhibitors
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Anticholinergic
Zinc (Zn2+) MPP+ • MPTP • Oxidopamine (6-hydroxydopamine) Etilevodopa • Foslevodopa • Melevodopa • XP-21279 Photopharmacology enables light-controlled modulation
List_of_dopaminergic_drugs
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Apomorphine
Abandoned antiparkinsonian agent
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Botiacrine
Chemical compound
approved for use in the treatment of Parkinson's disease. Etilevodopa Foslevodopa XP-21279 Buckingham J, Baggaley K, Roberts A, Szabo L (2010). Dictionary
Melevodopa
Antispasmodic drug
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Trihexyphenidyl
Chemical compound
It is the ethyl ester of levodopa. It was never marketed. Melevodopa Foslevodopa XP-21279 Djaldetti R, Giladi N, Hassin-Baer S, Shabtai H, Melamed E (November–December
Etilevodopa
Medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Selegiline
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Mofegiline
Progressive neurodegenerative disease
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Parkinson's_disease
Medication used to treat dyskinesia
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Amantadine
Abandoned anticholinergic
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Benapryzine
Medication for movement disorders
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Benzatropine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Tropatepine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Carbidopa
Skeletal muscle relaxant
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Orphenadrine
Dopamine agonist medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Ropinirole
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Entacapone
Dopamine agonist medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Bromocriptine
Substance related to dopamine functions
Parkinson's disease. Prodrugs of levodopa, including melevodopa, etilevodopa, foslevodopa, and XP-21279 also exist. They are inactive themselves but are converted
Dopaminergic
Medication used to treat Alzheimer's disease
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Memantine
Treatment of Parkinson's disease
EO (December 2022). "Safety and efficacy of continuous subcutaneous foslevodopa-foscarbidopa in patients with advanced Parkinson's disease: a randomised
Management of Parkinson's disease
Management_of_Parkinson's_disease
Dopamine agonist medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Rotigotine
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
LBT-3627
Medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Levodopa/benserazide
Sustained-release levodopa prodrug
However, one source appears to report its chemical structure. Etilevodopa Foslevodopa Melevodopa Hauser RA (2011). "Future treatments for Parkinson's disease:
XP-21279
Pharmaceutical drug classification
decarboxylase inhibitor N04BA06 Etilevodopa and decarboxylase inhibitor N04BA07 Foslevodopa and decarboxylase inhibitor N04BB01 Amantadine N04BC01 Bromocriptine
ATC_code_N04
Combination dopaminergic medication
taken orally in the form of tablets. Levodopa/carbidopa Foscarbidopa/foslevodopa Levodopa/carbidopa/entacapone Levodopa/benserazide "Melevodopa: Uses
Melevodopa/carbidopa
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Dihydroergocryptine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Dexetimide
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Cabergoline
Drug that binds to but does not activate muscarinic cholinergic receptors
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Muscarinic_antagonist
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
3-Hydroxymorphinan
Medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Rasagiline
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Phenglutarimide
Group of stereoisomers
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Biperiden
Type of medication
(5-HTP; oxitriptan). Other dopamine prodrugs, including etilevodopa, foslevodopa, melevodopa, XP-21279, DopAmide, DA-Phen, O,O'-diacetyldopamine, O
Neurotransmitter_prodrug
Medication used to treat high blood pressure
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Methyldopa
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Nitecapone
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Bornaprine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Tolcapone
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Sarizotan
Parkinson's disease medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Carbidopa/levodopa/entacapone
Dopamine agonist medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Pergolide
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Opicapone
Chemical compound often used as medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Benserazide
Group of stereoisomers
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Procyclidine
Type of medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Aromatic L-amino acid decarboxylase inhibitor
Aromatic_L-amino_acid_decarboxylase_inhibitor
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Lazabemide
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Aplindore
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Diphenylpyraline
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Metixene
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Sumanirole
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Mazaticol
Dopamine agonist medication
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Piribedil
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Talipexole
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Lisuride
fosfonet sodium (INN) fosfosal (INN) fosinopril (INN) fosinoprilat (INN) foslevodopa (INN) fosmenic acid (INN) fosmidomycin (INN) fosopamine (INN) fosphenytoin
List_of_drugs:_Fm–Ft
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Almoxatone
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Istradefylline
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Profenamine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Piroheptine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Etanautine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Chlorphenoxamine
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Ciladopa
Reversible monoamine oxidase B inhibitor
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Safinamide
Pharmaceutical drug
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Budipine
Pharmaceutical drug classification
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
ATC_code_N
Antiparkinsonian drug
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Pardoprunox
Chemical compound
precursors Levodopa# (+benserazide, +carbidopa, +carbidopa/entacapone) Foslevodopa (+foscarbodipa) Melevodopa (+carbidopa) DA receptor agonists Ergoline:
Etybenzatropine
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