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Class of chemical compounds
A glycinergic agent (or drug) is a chemical which functions to directly modulate the glycine system in the body or brain. Examples include glycine receptor
Glycinergic
Type of neuron in the retina
amacrine cells into subtypes. GABAergic, glycinergic, or neither: Amacrine cells can be either GABAergic, glycinergic or neither depending on what inhibitory
Amacrine_cell
Cluster of interneurons in the medulla oblongata
interneurons. Approximately half of preBötC interneurons are inhibitory, glycinergic or GABAergic. Inhibitory preBötC neurons modulate the amplitude as well
Pre-Bötzinger_complex
Affecting GABA systems in the brain
Adenosinergic Adrenergic Cannabinoidergic Cholinergic Dopaminergic Glutamatergic Glycinergic Histaminergic Melatonergic Monoaminergic Neurotransmission Opioidergic
GABAergic
Widely distributed inhibitory receptor in the central nervous system
the synaptic localization of GlyRs and the pharmacological profile of glycinergic currents. In mature adults, glycine is an inhibitory neurotransmitter
Glycine_receptor
Amino acid
whereas bicuculline is a weak one. Removal of glycine from inhibitory glycinergic synapses is hypothesized to be primarily mediated by glycine transporter
Glycine
Affecting glutamate systems in the brain
Adrenergic Cannabinoidergic Cholinergic Dopaminergic GABAergic GHBergic Glycinergic Histaminergic Melatonergic Monoaminergic Opioidergic Serotonergic Sigmaergic
Glutamatergic
Related to catecholamines (dopamine, adrenaline and noradrenaline)
Adenosinergic Cannabinoidergic Cholinergic GABAergic Glutamatergic Glycinergic Histaminergic Monoaminergic Opioidergic "Definition of CATECHOLAMINERGIC"
Catecholaminergic
Collection of brainstem nuclei related to hearing
spherical bushy cells in the ipsilateral cochlear nucleus and inhibitory, glycinergic input from the medial nucleus of the trapezoid body (MNTB). The MNTB
Superior_olivary_complex
Agents that modulate or mimic monoaminergic neurotransmitters
Adenosinergic Adrenergic Cannabinoidergic Cholinergic Dopaminergic GABAergic Glycinergic Histaminergic Melatonergic Opioidergic Serotonergic D'haenen, H. A. H
Monoaminergic
Protein-coding gene in the species Homo sapiens
transmitter in the spinal cord and brainstem. GlyT2 is a specific marker of glycinergic neurons and a member of the Na+ and Cl−-coupled transporter family SLC6
Sodium- and chloride-dependent glycine transporter 2
Sodium-_and_chloride-dependent_glycine_transporter_2
disease. Adrenergic Cannabinoidergic Cholinergic Dopaminergic GABAergic Glycinergic Histaminergic Melatonergic Monoaminergic Opioidergic Serotonergic Ren
Adenosinergic
therapeutic agents for chronic pain conditions, given that enhanced glycinergic inhibition can provide analgesia. The tricyclic sulfonamide compound
Glycine_receptor_agonist
Type of protein
AMPA, Kainate, mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, mGluR6, mGluR7 Glycinergic: Glycine Histaminergic: H1, H2, H3. H4 Opioidergic: μ, δ1, δ2, κ Serotonergic:
Neurotransmitter_receptor
Genetic disorder causing an exaggerated startle response
maintain a high concentration of glycine within the axon terminal of glycinergic neurons. Mutations of the SLC6A5 gene have been associated with hyperekplexia
Hyperekplexia
Group of neurons located in rostral ventrolateral medulla, and ventral respiratory column
controlling breathing and response to hypoxia. It consists primarily of glycinergic neurons which inhibit the activity of inspiratory neurons. In the respiratory
Botzinger_complex
Reflexive movement of eyes in the direction of motion to reduce motion blur
partially from asymmetric inhibition from starburst amacrine cells. Glycinergic inhibition produces a speed tuning preference for slow stimulus motion
Optokinetic_response
Region of the spinal cord involved in pain modulation
rat spinal cord (part 1): effects on axon terminals of GABAergic and glycinergic neurons". Anesthesiology. 92 (2): 473–84. doi:10.1097/00000542-200002000-00030
Substantia gelatinosa of Rolando
Substantia_gelatinosa_of_Rolando
facilitate GABAergic or glycinergic transmission. When Golgi cells are activated, granule cells and UBCs exhibit GABAergic and glycinergic currents, respectively
Golgi_cell
Glycine reuptake inhibitor
(2013-12-03). "ALX 1393 inhibits spontaneous network activity by inducing glycinergic tonic currents in the spinal ventral horn". Neuroscience. 253: 165–171
ALX-1393
Substance related to histamine functions
Adenosinergic Adrenergic Cannabinoidergic Cholinergic Dopaminergic GABAergic Glycinergic Melatonergic Monoaminergic Opioidergic Serotonergic "Histamine Agents
Histaminergic
Type of neuron in fish and amphibians
glutamatergic synapses on the M-cell. They also electrically activate glycinergic inhibitory interneurons that terminate on the M-cells. Despite the inhibitory
Mauthner_cell
Vision-related neuron type in mammals
synaptic input (red), coupling sites (yellow), TH1 cell input (cyan), and glycinergic synaptic output (blue) dimensionally mapped onto its surface. Small white
AII_amacrine_cells
example is opioidergics. Adenosinergic Cannabinoidergic Cholinergic GABAergic Glutamatergic Glycinergic Histaminergic Monoaminergic Opioidergic v t e
Neuropeptidergic
Form of synaptic inhibition mediated by increased membrane conductance
principles also apply to glycine receptor-mediated shunting in regions where glycinergic inhibition is prominent. Additional examples of fast feed-forward inhibition
Shunting_inhibition
Adenosinergic Adrenergic Cannabinoidergic Cholinergic Dopaminergic GABAergic Glycinergic Histaminergic Monoaminergic Opioidergic Serotonergic Alamo, Cecilio;
Melatonergic
Brain structure
throughout the nucleus, and synapse on both somata and in the neuropil. Glycinergic axon terminals, on the other hand, are more finely localized, with the
Lateral_lemniscus
Ability of a synapse to strengthen or weaken over time according to its activity
O, Ben-Ari Y (November 2002). "Long-term plasticity at GABAergic and glycinergic synapses: mechanisms and functional significance". Trends in Neurosciences
Synaptic_plasticity
blockers include amoxapine and ethanol (alcohol). Reuptake inhibitor Glycinergic GABA reuptake inhibitor Excitatory amino acid reuptake inhibitor Harsing
Glycine_reuptake_inhibitor
Working on the endocannabinoid neurotransmitters
cannabinoidergic. Adenosinergic Adrenergic Cholinergic Dopaminergic GABAergic Glycinergic Histaminergic Melatonergic Monoaminergic Opioidergic Serotonergic Palmer
Cannabinoidergic
Protein-coding gene in the species Homo sapiens
external side of plasma membrane soma neuron projection calyx of Held glycinergic synapse integral component of presynaptic membrane integral component
Glycine_receptor,_alpha_1
Protein-coding gene in the species Homo sapiens
membrane chloride channel complex plasma membrane neuron projection glycinergic synapse Biological process neuropeptide signaling pathway chloride transmembrane
GLRA2
Classification of chemicals that directly modulate opioid neuropeptide systems
Adenosinergic Adrenergic Cannabinoidergic Cholinergic Dopaminergic GABAergic Glycinergic Histaminergic Melatonergic Monoaminergic Serotonergic Burford NT, Clark
Opioidergic
Capacity of neurons to regulate their own excitability relative to network activity
synapses, and neuroligin 3 is present in both. Neuroligin 4 is present in glycinergic synapses which are major contributors to the regulation of neuronal excitability
Homeostatic_plasticity
Protein family
a different protein. Resistance is dependent one the synaptic site. Glycinergic synapses are able to function like normal with the deletion of collybistin
Collybistin
Medical condition
co-activating NMDAR). GLYT1 protein is located on astrocytes that are next to glycinergic neurons to clear glycine swiftly from the synaptic cleft. Consequently
GLYT1_encephalopathy
Protein-coding gene in the species Homo sapiens
chloride transmembrane transport ion transport synaptic transmission, glycinergic chloride transport neuropeptide signaling pathway protein homooligomerization
GLRA3
Protein-coding gene in the species Homo sapiens
integral component of plasma membrane plasma membrane GABA-ergic synapse glycinergic synapse neuron projection Biological process response to amino acid startle
GLRB
Protein-coding gene in the species Homo sapiens
membrane intracellular anatomical structure spanning component of membrane glycinergic synapse dopaminergic synapse GABA-ergic synapse symmetric, GABA-ergic
NLGN2
Medical condition
overactivation of NMDA receptors through excessive stimulation at the glycinergic binding site, resulting in excitotoxicity. This process contributes to
Glycine_encephalopathy
recruiting motoneurons during locomotor-like activity. GABAergic and glycinergic neurons are both involved in both bilateral limb coordination and rostrocaudal
Neural substrate of locomotor central pattern generators in mammals
Neural_substrate_of_locomotor_central_pattern_generators_in_mammals
Chinese neuroscientist (born 1956)
2001 Cui, J., Ma, Y.-P., Lipton, S.A., Pan Z.-H. Glycine receptors and glycinergic synaptic input at the axon terminals of mammalian retinal rod bipolar
Zhuo-Hua_Pan
Synapse in the mammalian auditory central nervous system
signal from the GBCs to the principal neurons of the MNTB, which are glycinergic, thus hyperpolarizing cells in the lateral superior olive (LSO) nuclei
Calyx_of_Held
Protein-coding gene in the species Homo sapiens
transport transmembrane transport regulation of synaptic transmission, glycinergic Sources:Amigo / QuickGO Orthologs Databases NCBI: entry; OMA: entry Species
Sodium- and chloride-dependent glycine transporter 1
Sodium-_and_chloride-dependent_glycine_transporter_1
Protein-coding gene in humans
superfamily. Other members of this superfamily include GABA A, GABA C, glycinergic receptors, and serotonin receptors. Since CHRFAM7A is a human specific
CHRFAM7A
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