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Protein-coding gene in the species Homo sapiens
HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E
HLA-E
Genes on human chromosome 6
and three minor MHC class I genes in HLA. Major MHC class I HLA-A HLA-B HLA-C Minor genes are HLA-E, HLA-F and HLA-G. β2-microglobulin binds with major
Human_leukocyte_antigen
Biomolecule
biology, Qa-1b is a MHC class I molecule and is the functional homolog of HLA-E in humans. Qa-1b is characterised by its limited polymorphisms and small
Qa-1b
Protein-coding gene in the species Homo sapiens
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility
HLA-A
Type of cell receptor
such as HLA-A, HLA-B or HLA-C, NKG2A allows immune cells to indirectly monitor the expression levels of HLA-A/B/C through complexes of HLA-E and signal
NKG2A
Subclass of HLA-D antigens that consist of alpha and beta chains
HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human
HLA-DR
Type of antigen
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex
HLA-B27
Protein-coding gene in the species Homo sapiens
HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene. It is an empty intracellular molecule
HLA-F
Protein of the immune system
polymorphic HLA-A (HLA-A) HLA-B (HLA-B) HLA-C (HLA-C) Less polymorphic HLA-E (HLA-E) HLA-F (HLA-F) HLA-G (HLA-G) HLA-K (pseudogene) HLA-L (pseudogene)
MHC_class_I
Human leukocyte antigen serotype within the HLA-A serotype group
of the HLA System revised the nomenclature for HLAs. Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is
HLA-A*02
Protein-coding gene in the species Homo sapiens
critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system
HLA-B
Human leukocyte antigen serotype
HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products. B35 is one of the largest B serotype groups, it currently
HLA-B35
glycoproteins class I (HLA-E in human and Qa-1 molecules in the mouse). CD94/NKG2 family includes seven members: NKG2A, B, C, D, E, F and H. Genes encoding
CD94/NKG2
Protein-coding gene in the species Homo sapiens
HLA-C alleles that are Class-I MHC receptors. HLA-C, localized proximal to the HLA-B locus, is located on the distal end of the HLA region. Most HLA-C:B
HLA-C
HLA-B5 (B5) is an HLA-B serotype. B5 is a broad antigen serotype that recognizes the B51 and B52 split antigen serotypes. Marsh, S. G.; Albert, E. D.;
HLA-B5
Human leukocyte antigen serotype
HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system. The serotype is determined by the antibody recognition of β2 subset of DQ β-chains
HLA-DQ2
HLA A1-B8 (Also:HL A1,8; HL A1,A8; HLA A1-Cw7-B8; HLA A*01-B*08, HLA A*0101-B*0801, HLA A*0101-Cw*0701-B*0801; HLA A*01:01-C*07:01-B*08:01) is a multigene
HLA_A1-B8_haplotype
Cell surface proteins, part of the adaptive immune system
most studied HLA genes are the nine classical MHC genes: HLA-A, HLA-B, HLA-C, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, and HLA-DRB1. In humans
Major histocompatibility complex
Major_histocompatibility_complex
Molecule triggering an immune response
HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles
HLA-DR4
Protein-coding gene in humans
interact and form dimers with CD94. The CD94/NKG2C heterodimer can bind to HLA-E and this binding leads to NK cells activation. During infection with human
KLRC2
Serotype
HLA-B51 (B51) is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products. B51 is a split antigen of the broad antigen B5, and
HLA-B51
Serotype of cell surface receptors
HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among centenarians. The serology for the
HLA-DR1
Human leukocyte antigen serotype
HLA-Cw4 (Cw4) is a human leukocyte antigen serotype within HLA-C serotype group. (For more general information on HLA serotypes, please see the article:
HLA-Cw4
Protein-coding gene in the species Homo sapiens
HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta
HLA-DRB1
Standard for distributed simulation
The High Level Architecture (HLA) is a standard for distributed simulation, used when building a simulation for a larger purpose by combining (federating)
High_Level_Architecture
Type of cytotoxic lymphocyte
both classical MHC I (HLA-A, HLA-B, HLA-C) and nonclassical Mamu-G (HLA-G) in primates. Some KIRs are specific for certain HLA subtypes. Most KIRs are
Natural_killer_cell
cells to avoid immune system is upregulation of non-classical MHC I (HLA-E, HLA-F, HLA-G) which prevents NK-mediated immune reaction by interaction with
Immunoediting
Human leukocyte antigen serotype
HLA-B8 (B8) is an HLA-B serotype. The serotype identifies the HLA-B*08 gene products. (For terminology help see: HLA-serotype tutorial) HLA-B8, previously
HLA-B8
Mammalian protein found in Homo sapiens
surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells. Natural killer (NK) cells are a distinct lineage of lymphocytes
KLRD1
HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes. DR3 is a component gene-allele of the AH8.1 haplotype in Northern and Western
HLA-DR3
Human leukocyte antigen serotype, associated with coeliac disease
HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 broad antigen. DQ8 is determined
HLA-DQ8
Skin disease
non-self epitope on one of their various HLA protein forms (HLA-A, HLA-B, HLA-C, HLA-DM, HLA-DO, HLA-DP, HLA-DQ, or HLA-DR) can bind to a T-cell receptor and
Stevens–Johnson_syndrome
Component of MHC class I molecules
alloantigen). Nevertheless, the β2 microglobulin gene is outside of the MHC (HLA) locus, on a different chromosome. An additional function is association
Beta-2_microglobulin
Human leukocyte antigen serotype
HLA-B58 (B58) is an HLA-B serotype. B58 is a split antigen from the B17 broad antigen, the sister serotype B57. The serotype identifies the more common
HLA-B58
Group of adverse drug reactions involving the skin and mucosa
cells. They load processed peptides onto MHC class II (i.e. HLA-DM, HLA-DO, HLA-DP, HLA-DQ, or HLA-DR) proteins and thereon present the peptides to CD4+
Severe cutaneous adverse reactions
Severe_cutaneous_adverse_reactions
Classification of leukocyte antigens
Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were initially identified by categorizing
History and naming of human leukocyte antigens
History_and_naming_of_human_leukocyte_antigens
Human leukocyte antigen serotype
HLA-B57 (B57) is an HLA-B serotype. B57 is a split antigen from the B17 broad antigen, the sister serotype being B58. The serotype identifies the more
HLA-B57
Human leukocyte antigen serotype
HLA-B7 (B7) is an HLA-B serotype. The serotype identifies the more common HLA-B*07 gene products. (For terminology help see: HLA-serotype tutorial) B7
HLA-B7
Part of the human genome
HLA-Cw7 (Cw7) is a human leukocyte antigen serotype within HLA-C serotype group. (For more general information on HLA serotypes, please see the article:
HLA-Cw7
HLA-DR serotype
HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products. DR15 is found at high levels from Ireland to Central
HLA-DR15
Human leukocyte antigen serotype
HLA-B52 (B52) is an HLA-B serotype. The serotype identifies the more common HLA-B*52 gene products. B52 is a split antigen of the broad antigen B5, and
HLA-B52
Human antigen receptor of the HLA group
DPβ. DPα and DPβ are encoded by two loci, HLA-DPA1 and HLA-DPB1, that are found in the MHC Class II (or HLA-D) region in the Human Leukocyte Antigen complex
HLA-DP
complex (MHC) class II membrane-bound proteins. HLA-DM is encoded by the genes HLA-DMA and HLA-DMB. HLA-DM is a molecular chaperone that works in lysosomes
HLA-DM
Type of arthritis of the spine
known as the HLA-B27 antigen, though the genetic correlation varies across populations (e.g., only 70% of AS patients in Turkey are HLA-B27 positive)
Ankylosing_spondylitis
King of Martaban
invasion by Sukhothai, which Sanda Min Hla and her new king Binnya E Law (r. 1330–1348) decisively defeated. Saw E Kan-Kaung was the elder child of Queen
Saw_E
Human leukocyte antigen serotype
HLA-A11 (A11) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody recognition of α11 subset
HLA-A11
Protein in humans
complex, class I, Y (pseudogene) is a protein that in humans is encoded by the HLA-Y gene. "Entrez Gene: Major histocompatibility complex, class I, Y (pseudogene)"
HLA-Y
Human leukocyte antigen serotype
HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group. The serotype is determined by the antibody recognition of β6 subset
HLA-DQ6
Human leukocyte antigen serotype
HLA-B67 (B67) is an HLA-B serotype. The serotype identifies the more common HLA-B*67 gene products. B67 is region specific recombinant haplotype formed
HLA-B67
HLA-DR13 is genetically linked to HLA-DR52 and HLA-DQ5 (HLA-DQ1) serotypes. derived from IMGT/HLA DR1404 - 3% DR4 - 25% Garavito G, Yunis E, Egea E,
HLA-DR14
on legendary 1985 Bears championship team, dies Zemřel Richard Tesařík: Hlas legendárního Rybitví skrýval bolest, o které věděl málokdo (in Czech) Former
Deaths_in_2026
Protein domain
HLA-A; HLA-B; HLA-B35; HLA-B57; HLA-C; HLA-CW; HLA-Cw; HLA-D; HLA-DMA; HLA-DMB; HLA-DOA; HLA-DOB; HLA-DP; HLA-DPA1; HLA-DPB1; HLA-DQA1; HLA-DQA2; HLA-DQB1;
Immunoglobulin_C1-set_domain
Broad-antigen serotype
HLA-DR5 (DR5) is a broad-antigen serotype that is further split into HLA-DR11 and HLA-DR12 antigen serotypes. Except for a few DRB1* alleles, the reactivity
HLA-DR5
Autoimmune disorder
typical HLA-DQ2 or HLA-DQ8 alleles. The vast majority of people with coeliac disease have one of two types (out of seven) of the HLA-DQ protein. HLA-DQ is
Coeliac_disease
Pluripotent stem cell generated directly from a somatic cell
ligands inhibiting NK-cells, such as HLA-E and CD47 has been used. HLA-C is left unchanged, since the 12 common HLA-C alleles are enough to cover 95% of
Induced_pluripotent_stem_cell
HLA DR3-DQ2 is a double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype. Certain HLA DR and DQ
HLA_DR3-DQ2
HLA-NET is a network targeted to the study of Human leukocyte antigen (HLA) from a populational point of view. The network was initiated by COST Action
HLA-NET
Buddhist temple in Sagaing, Myanmar
Zedi Hla (စေတီလှ) is a historic Buddhist pagoda located on the Minwun mountain ridge in Sagaing, Myanmar. The pagoda was built in 1315 by Athinkhaya Saw
Zedi_Hla
Protein-coding gene in the species Homo sapiens
receptor-mediated recognition of HLA-E". Eur. J. Immunol. 32 (4): 936–44. doi:10.1002/1521-4141(200204)32:4<936::AID-IMMU936>3.0.CO;2-M. PMID 11920559. v t e
TRA_(gene)
HLA-DR8 (DR8) is a HLA-DR serotype that recognizes the DRB1*0801 to *0807, and *0810 to *0812 gene products. The serological reaction of DR8 is relatively
HLA-DR8
Serotype that covers a broad range of HLA-DQ haplotypes
HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1; later, it was
HLA-DQ1
Human leukocyte antigen serotype
HLA-B13 (B13) is an HLA-B serotype. The serotype identifies the more common HLA-B*13 gene products. (For terminology help see: HLA-serotype tutorial) Marsh
HLA-B13
Genetic HLA-B serotype
HLA-B78 (B78) is an HLA-B serotype. The serotype identifies the more common HLA-B*78 gene products. B78 is more common in West and North Africa, but is
HLA-B78
A, Hengel H, Cerwenka A (December 2014). "IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion". The Journal of Clinical Investigation
Trained_immunity
Human leukocyte antigen serotype
HLA-B47 (B47) is an HLA–B serotype. The serotype identifies the HLA-B*47 gene products (B*4701, B*4702, B*4703) . Comparison of B47 nucleotide sequence
HLA-B47
Human leukocyte antigen serotype
HLA-B60 (B60) is an HLA - B serotype. B60 is a split antigen serotype that recognizes certain B40 serotypes. Ways JP, Lawlor DA, Wan AM, Parham P (1987)
HLA-B60
Protein-coding gene in the species Homo sapiens
Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene
HLA-DQB1
Human leukocyte antigen serotype
HLA-B44 (B44) is an HLA-B serotype. The serotype identifies the B*44 gene-allele protein products of HLA-B. B44 is a split antigen of the broad antigen
HLA-B44
Human leukocyte antigen serotype
HLA-A31 (A31) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α31 subset of
HLA-A31
Clusters of receptor proteins
(2008-03-17). "CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence". Journal of Experimental Medicine. 205
Paired_receptors
Mammalian protein found in Homo sapiens
molecules are nonclassical MHC class I molecules – Qa1b molecules in mice and HLA-E in humans. These molecules both present sequences from the digested leading
NKG2
Human leukocyte antigen serotype
HLA-A33 (A33) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α33 subset of
HLA-A33
Human leukocyte antigen serotype
HLA-A3 (A3) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α3 subset of HLA-A
HLA-A3
Human leukocyte antigen serotype
HLA-B49 (B49) is an HLA-B serotype. B49 is a split antigen from the B21 broad antigen, the sister serotype B50. The serotype identifies the more common
HLA-B49
Protein family
preproteins. A nine amino acid-long cleavage fragment is then presented on HLA-E receptors and modulates the activity of natural killer cells. SPP also plays
Signal_peptide_peptidase
Protein-coding gene in the species Homo sapiens
HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene. HLA-DRA encodes the alpha subunit
HLA-DRA
HLA-DR11 (DR11) is a HLA-DR serotype that recognizes the DRB1*1101 to *1110. DR11 serotype is a split antigen of the older HLA-DR5 serotype group which
HLA-DR11
Sequence of amino acids
usually considered as stimulatory receptors contain ITIM-like sequences, e.g. IL-4. In contrast, the activating NK cell receptor NKp44 contains an ITIM
Immunoreceptor tyrosine-based inhibitory motif
Immunoreceptor_tyrosine-based_inhibitory_motif
HLA-B serotype
HLA-B18 (B18) is an HLA-B serotype. The serotype identifies the more common HLA-B*18 gene products. (For terminology help see: HLA-serotype tutorial) B*1801
HLA-B18
British legal philosopher (1907–1992)
OCLC 54778415. Mullender, Richard: "Nicola Lacey, A Life of H.L.A. Hart: The Nightmare and the Noble Dream – H.L.A. Hart in Anglo-American Context", Web Journal of
H._L._A._Hart
HLA-DR17 (DR17) is an HLA-DR serotype that recognizes the DRB1*0301 and *0304 gene products. DR17 is found at high frequency in Western Europe (such as
HLA-DR17
Protein-coding gene in the species Homo sapiens
HLA class II histocompatibility antigen, DP(W2) beta chain is a protein that in humans is encoded by the HLA-DPB1 gene. HLA-DPB belongs to the HLA class
HLA-DPB1
Human leukocyte antigen serotype
HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products. B59 is a hybrid between B*55 and B*51. B59 is more
HLA-B59
Human leukocyte antigen serotype
HLA-A23 (A23) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α23 subset of
HLA-A23
Human leukocyte antigen serotype
HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56. The serotype identifies the more
HLA-B54
Human genotype
HLA A1-B8-DR3-DQ2 haplotype (Also: AH8.1, COX, Super B8, ancestral MHC 8.1 or 8.1 ancestral haplotype) is a multigene haplotype that covers a majority
HLA_A1-B8-DR3-DQ2
Human leukocyte antigen serotype
HLA-B63 (B63) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B. B63 is one of many split antigens of the
HLA-B63
Human leukocyte antigen serotype
HLA-B40 (B40) is an HLA - B serotype. B40 is composed of the B60 and B61 split antigen serotypes. B*40:05 is poorly recognized by B40, B60, or B61. Marsh
HLA-B40
CD27, CD274 (PD-L1), CD276 (B7-H3), CD8A, CMKLR1, CXCL9, CXCR6, HLA-DQA1, HLA-DRB1, HLA-E, IDO1, LAG3, NKG7, PDCD1LG2 (PDL2), PSMB10, STAT1, and TIGIT.
Immunologic constant of rejection
Immunologic_constant_of_rejection
Human leukocyte antigen serotype
HLA-B39 (B39) is an HLA-B serotype. The serotype identifies the more common HLA-B*39 gene products. B39 is a split antigen of the broad antigen B16, and
HLA-B39
Human leukocyte antigen DQ4 serotype
HLA-DQ4 (DQ4) is a serotype subgroup within HLA-DQ(DQ) serotypes. The serotype is determined by the antibody recognition of β4 subset of DQ β-chains.
HLA-DQ4
Human leukocyte antigen serotype
HLA-B53 (B53) is an HLA-B serotype. The serotype identifies the more common HLA-B*53 gene products. The B53 sequence is identical to B35 but short sequence
HLA-B53
Human leukocyte antigen serotype
HLA-A9 (A9) is a broad antigen HLA-A serotype that recognized the HLA-A23 and HLA-A24 serotypes. A*2402 appears to have evolved from A*23 alleles by a
HLA-A9
HLA DQB1*06:02 is an allele of the human leukocyte antigen class II gene that is strongly associated with an increased risk of developing type 1 narcolepsy
HLA_DQB1*06:02
Human leukocyte antigen serotype
HLA-B62 (B62) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B. B62 is the largest of many split antigens
HLA-B62
Protein-coding gene in the species Homo sapiens
S2CID 6933602. Wooden SL, Kalb SR, Cotter RJ, Soloski MJ (2005). "Cutting edge: HLA-E binds a peptide derived from the ATP-binding cassette transporter multidrug
ABCC10
Protein complex on the surface of T cells that recognizes antigens
overcoming this restriction is to instead target monomorphic HLA-like molecules such as HLA-E, MHC-related protein 1 (MR1) and cluster of differentiation
T-cell_receptor
Human leukocyte antigen serotype
HLA-B45 (B45) is an HLA-B serotype. The serotype identifies the B*45 gene-allele protein products of HLA-B. B45 is a split antigen of the broad antigen
HLA-B45
Human leukocyte antigen serotype
HLA-A74 (A74) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α74 subset of
HLA-A74
Human leukocyte antigen serotype
HLA-A1 (A1) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody recognition of α1 subset
HLA-A1
travel, tourism, insurance
HLA E
HLA E
HLA E
HLA E
HLA E
HLA E
HLA E
HLA E
HLA E
travel, tourism, insurance