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Classifying cells of the immune system
Immunophenotyping is a technique used to study the protein expressed by cells. This technique is commonly used in basic science research and laboratory
Immunophenotyping
Classification in immunology
and investigation of cell surface molecules providing targets for immunophenotyping of cells. In terms of physiology, CD molecules can act in numerous
Cluster_of_differentiation
Blood cancer characterized by overproduction of lymphoblasts
cytogenetics (in particular the presence of Philadelphia chromosome), and immunophenotyping establish whether the leukemic cells are myeloblastic (neutrophils
Acute_lymphoblastic_leukemia
Type of white blood cell
leukemia or lymphoma. Basophils of mice and humans have consistent immunophenotypes, including FcεRI+, CD123, CD49b(DX-5)+, CD69+, Thy-1.2+, 2B4+, CD11bdull
Basophil
Lab technique in biology and chemistry
multi-parametric analysis (understand more properties about a cell). Immunophenotyping is the analysis of heterogeneous populations of cells using labeled
Flow_cytometry
Medical condition
disease display a mature T-cell immunophenotype, with the majority of cases showing a CD4-/CD8+ T-cell subset immunophenotype versus other permutations of
Large granular lymphocytic leukemia
Large_granular_lymphocytic_leukemia
Study of the chemistry of the immune system
precipitation and agglutination reactions, immunoelectrophoresis, immunophenotyping, immunochromatographic assay and flow cytometry. One of the earliest
Immunochemistry
Type of blood cancer
distinguished by their morphology, (i.e. microscopic appearance), immunophenotype, (i.e. expression of certain marker proteins), clinical findings, and/or
Diffuse_large_B-cell_lymphoma
American biotechnology company
BioLegend manufactures products in the areas of neuroscience, cell immunophenotyping, cytokines and chemokines, adhesion, cancer research, T regulatory
BioLegend
Hematologic cancer that affects lymphocytes
features characteristic of different types of lymphoma. These include: Immunophenotyping Flow cytometry Fluorescence in situ hybridization testing According
Lymphoma
Medical condition
virus infection.[citation needed] The relevant markers that define the immunophenotype for SMZL are shown in the adjacent table. The lack of CD5 expression
Splenic marginal zone lymphoma
Splenic_marginal_zone_lymphoma
Adult telomerase-positive stem cells. A unique, distinct group of Adult stem cells
Adult telomerase-positive stem cells (aTPSCs) are a proposed population of endogenous adult stem cells described in publications by Henry E. Young and
Adult telomerase positive stem cells
Adult_telomerase_positive_stem_cells
Type of cancer of lymph nodes
study the cancer cells: Immunohistochemistry. Cytogenetic analysis. Immunophenotyping. Other tests and procedures may be done depending on the signs and
Non-Hodgkin_lymphoma
platelets, which play a central role in blood clotting and tissue repair. Immunophenotype is the pattern of surface markers on a cell that are important for
Megakaryocyte–erythroid progenitor cell
Megakaryocyte–erythroid_progenitor_cell
Medical condition
(December 1988). "Clonal gene rearrangement patterns correlate with immunophenotype and clinical parameters in patients with angioimmunoblastic lymphadenopathy"
Angioimmunoblastic T-cell lymphoma
Angioimmunoblastic_T-cell_lymphoma
Tumors that affect the blood, bone marrow, lymph, and lymphatic system
these diseases can now be classified by cytogenetics (AML, CML) or immunophenotyping (lymphoma, myeloma, CLL) of the malignant cells.[citation needed]
Tumors of the hematopoietic and lymphoid tissues
Tumors_of_the_hematopoietic_and_lymphoid_tissues
Loose connective tissue composed mostly by adipocytes
characteristics. These depot-dependent features include proliferation rate, immunophenotype, differentiation potential, gene expression, as well as sensitivity
Adipose_tissue
Type of blood and immune-system cancer
cells with prominent nucleoli and an unusual CD45−, CD30+, CD15+/− immunophenotype. In approximately 50% of cases, the Reed–Sternberg cells are infected
Hodgkin_lymphoma
Endocrine gland
deficiency in other cell lines – such as low platelets or anaemia. Immunophenotyping will reveal cells that are CD3, a protein found on T cells, and help
Thymus
Medical specialty
defects such as chromosomal translocation Flow immunophenotyping – the determination of the immunophenotype of cells using flow cytometry techniques. It
Anatomical_pathology
Cancer of the myeloid line of blood cells
marrow eosinophilia (M4Eo) and inv(16)(p13q22) exhibits a specific immunophenotype with CD2 expression". Blood. 81 (11): 3043–3051. doi:10.1182/blood
Acute_myeloid_leukemia
Routine laboratory test of blood cells
After abnormal cells are identified, additional techniques such as immunophenotyping by flow cytometry can be used to identify markers that provide additional
Complete_blood_count
Medical science consortium
complementary knowledge and skills in the field of flow cytometry and immunophenotyping. During 2012 both SMEs left the project so it obtained full scientific
EuroFlow
Medical condition
recognized as myeloid based on morphology and cytochemistry, but immunophenotyping demonstrates myeloid antigens. In acute myeloblastic leukemia (M0)
Minimally differentiated acute myeloblastic leukemia
Minimally_differentiated_acute_myeloblastic_leukemia
Excess number of eosinophil cells in the blood
proliferation of lymphocytes with the CD3 negative, CD41 positive immunophenotype may occur during the disorders progression to lymphoma. Reports on
Eosinophilia
Medical condition
in either the sinusoids, portal triad regions, or both. No distinct immunophenotype abnormality for CNL has been described. See OHSU 2013 findings of gene
Chronic_neutrophilic_leukemia
Common application of immunostaining
technique is even more widely used in diagnostic surgical pathology for immunophenotyping tumors (e.g. immunostaining for e-cadherin to differentiate between
Immunohistochemistry
White blood cell that secretes large volumes of antibodies
Press. p. 102. ISBN 978-3-7186-0596-5. Rawstron, Andy C. (2006). "Immunophenotyping of Plasma Cells". Current Protocols in Cytometry. 36: Unit6.23. doi:10
Plasma_cell
Medical condition
morphology observed in solid organs are observed in peripheral blood. The immunophenotype for hepatosplenic T-cell lymphoma is a post-thymic, immature T-cell
Hepatosplenic_T-cell_lymphoma
Medical condition
requires integration of morphology with diagnostic tests including immunophenotyping and chromosome analysis (cytogenetics). The malignant B cells are
B-cell prolymphocytic leukemia
B-cell_prolymphocytic_leukemia
"OMIP-010: a new 10-color monoclonal antibody panel for polychromatic immunophenotyping of small hematopoietic cell samples". Cytometry Part A. 81 (6): 453–5
Optimized Multicolor Immunofluorescence Panel
Optimized_Multicolor_Immunofluorescence_Panel
Liquid component of blood
et al. (2019). "Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients". PLOS
Blood_plasma
low-dimensional immunophenotyping. However, high-dimensional immunophenotyping is now a possibility. The types of high-dimensional immunophenotyping can be broadly
Immunome
Bone marrow cancer in which lymphocytes are overproduced
Blood Smear, Bone Marrow Aspiration and Biopsy, Iron Storage, and Immunophenotype in Patients with Chronic Lymphocytic Leukemia". Iranian Journal of
Chronic_lymphocytic_leukemia
Group of medical conditions
cell tumor of tendon sheath and pigmented villonodular synovitis: immunophenotype suggests a synovial cell origin". Human Pathology. 26 (7): 771–5. doi:10
Villonodular_synovitis
Medical condition
predominance of clonal plasma cells in the bone marrow with an abnormal immunophenotype (CD38+ CD56+ CD19−) mixed in with cells of a normal phenotype (CD38+
Monoclonal gammopathy of undetermined significance
Monoclonal_gammopathy_of_undetermined_significance
Cell found in connective tissue
are also mononuclear. Healthy mature mast cells present a distinct immunophenotype in which expression of CD117 is high; CD33, CD9 and CD71 are intermediate;
Mast_cell
Medical condition
CD1a. The immunophenotype CD4+/CD8- is present in 60% of cases, the CD4+/CD8+ immunophenotype is present in 25%, and the CD4-/CD8+ immunophenotype is present
T-cell prolymphocytic leukemia
T-cell_prolymphocytic_leukemia
Medical condition
AL, Muirhead KA (July 1989). "Procedural guidelines for performing immunophenotyping by flow cytometry". Clin. Immunol. Immunopathol. 52 (1): 48–60. doi:10
Lymphoid_leukemia
Medical researcher
Profiling in Coronary Artery Disease: The Role of State‐of‐the‐Art Immunophenotyping With Mass Cytometry in the Diagnosis of Atherosclerosis". Journal
Gemma_Figtree
Medical condition
Grimaldi ME, Neri C, Nanni L, Neri G (January 2010). "Morphology and immunophenotyping of a monolateral ovotestis in a 46,XderY/45,X mosaic individual with
Androgen insensitivity syndrome
Androgen_insensitivity_syndrome
Type of cell
by their specific surface marker expression, as determined through immunophenotyping, which reflects their transitional stage in monocyte development.
Promonocyte
Medical condition
Urticaria Pigmentosa into Indolent Systemic Mastocytosis: Abnormal Immunophenotype of Mast Cells without Evidence of c-kit Mutation ASP-816-VAL". Leukemia
Mastocytosis
Cancer of the lymphatic system
immunodeficiency-associated variants. By morphology (i.e., microscopic appearance), immunophenotype, and genetics, the variants of Burkitt lymphoma are alike. The endemic
Burkitt_lymphoma
Genetic disorder leading to severe impairment of the immune system
Farouqi B, Benslimane A, Jilali N, Oudghiri M, Bousfiha A (2011). "Immunophenotyping of severe combined immunodeficiency in Morocco". IBS J Sci. 26 (4):
Severe combined immunodeficiency
Severe_combined_immunodeficiency
Medical condition
ISSN 0271-5333. PMID 19168843. Varga Z, Mallon E (Oct 2009). "Histology and Immunophenotype of Invasive Lobular Breast Cancer. Daily Practice and Pitfalls" (PDF)
Invasive_lobular_carcinoma
Medical condition
aspiration + biopsy, immunohistochemical stains, electron microscopy, immunophenotyping, peripheral blood smear, chromosomal analysis + FISH panel to rule
Acute_basophilic_leukemia
Medical condition
(May 2004). "B- and T-cell markers in opsoclonus-myoclonus syndrome: immunophenotyping of CSF lymphocytes". Neurology. 62 (9): 1526–32. doi:10.1212/WNL.62
Opsoclonus_myoclonus_syndrome
Medical condition
abnormal immunophenotype, i.e. they express CD3-, CD4+ cluster of differentiation cell surface antigens. These same aberrant T cell immunophenotypes are found
Gleich's_syndrome
Spectrum of blood disorders
myeloma and similar to that for plasma cell leukemia. Flow cytometry immunophenotyping of blood cells to detect clonal phenotypes of plasma cells seen in
Plasma_cell_dyscrasias
Group of proteins
"Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology". Cancer Immunology
CD16
Disease in dogs and other canines
(2003). "Canine transmissible venereal tumour: cytogenetic origin, immunophenotype, and immunobiology. A review". The Veterinary Quarterly. 25 (3): 101–11
Canine transmissible venereal tumor
Canine_transmissible_venereal_tumor
Group of disorders
attempts to define diagnostic criteria for PTCL, NOS by histology and immunophenotyping have not translated into clinical practice. Gene expression profiling
Epstein–Barr virus–associated lymphoproliferative diseases
Epstein–Barr_virus–associated_lymphoproliferative_diseases
Medical condition
aberrant clones of T cells. The aberrant T cell clone, as defined by immunophenotyping their expression of certain cell surface molecules, the cluster of
Lymphocyte-variant hypereosinophilia
Lymphocyte-variant_hypereosinophilia
Medical condition
cells more frequently express CD28 than do sPCL plasma cells. Thus, immunophenotyping supports that notion that multiple myeloma, sPCL, and pPCL show critically
Plasma_cell_leukemia
Type of cancerous immune cells
cells and look at their shape. Skin biopsy Checks for signs of cancer Immunophenotyping Flow cytometry T-cell receptor gene rearrangement test Liver Function
Lutzner_cells
Medical condition
Naeim, Faramarz, ed. (2013). Atlas of Hematopathology. Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches. P. Nagesh Rao, Sophie Song
Leukocytosis
Medical condition
cytologic characteristics, and most importantly the tumor cells' immunophenotype. The diagnosis is frequently confirmed by correlation with peripheral
Leukemia_cutis
Overview of and topical guide to cell biology
found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways,
Outline_of_cell_biology
Protein family
PMID 7541024. Naeim F, Rao PN, Song SX, Grody WW (2013). "Principles of Immunophenotyping". Atlas of Hematopathology. pp. 25–46. doi:10.1016/b978-0-12-385183-3
CD79
Protein-coding gene in the species Homo sapiens
2013.06.022. PMC 3717207. PMID 23870131. "Infection and Immunity Immunophenotyping (3i) Consortium".[permanent dead link] Maruyama K, Sugano S (January
TREM1
Medical condition
angioinvasion, and the monotonous infiltrate may be diffuse or patchy. The immunophenotype of this disease is the same as extranodal NK/T-cell lymphoma, nasal
Aggressive_NK-cell_leukemia
Medical condition
Epstein–Barr virus in medullary carcinoma of the breast as demonstrated by immunophenotyping, in situ hybridization and polymerase chain reaction". American Journal
Lymphoepithelioma-like carcinoma
Lymphoepithelioma-like_carcinoma
Human disease
histopathologic examination by biopsy of lymph nodes may be needed. The immunophenotype of ATLL includes positive markers such as CD2, CD3, CD4, CD5, and CD25
Adult T-cell leukemia/lymphoma
Adult_T-cell_leukemia/lymphoma
Medical condition
same time and used together to help with diagnosis. Tests called immunophenotyping and cytogenetic analysis are performed on the cells to further determine
Childhood_leukemia
Austrian oncologist
the IDH gene (glioblastoma multiforme) and the BRAF gene and the immunophenotype inlcuing the role of PD-L1 in gliomas and brain metastases are highly
Matthias_Preusser
Mammalian protein found in Homo sapiens
Amini RM, Book M, Roos G, Erlanson M, et al. (2005). "Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis". Mod
Neprilysin
Medical condition
The malignant B-cells in THRLBCL are definitively identified by immunophenotyping to detect B-cell marker proteins (e.g. CD19, CD20, CD22, CD79a, and/or
T cell/histiocyte-rich large B-cell lymphoma
T_cell/histiocyte-rich_large_B-cell_lymphoma
Blood marrow cancer originating in megakaryoblast cells
to obtain a bone marrow aspirate because of marrow fibrosis; and immunophenotyping analyses of platelet precursor cells lineage as determined by flow
Acute megakaryoblastic leukemia
Acute_megakaryoblastic_leukemia
German immunologist, biomedical researcher
analysis of the murine myeloid cell system. This early single-cell immunophenotyping study of phagocytes across tissues revealed the complexity of myeloid
Burkhard_Becher
Group of lymphomas
patients at a median of 4–5 years after the original diagnosis of EMZL. Immunophenotyping or the neoplastic large B cells in these lesions shows that they express
Marginal_zone_lymphoma
South Korean immunologist (born 1971)
W., Ahn, J. Y., Choi, S. J., Lee, H., ... & Shin, E. C. (2020). Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons
Eui-Cheol_Shin
Protein which in humans is encoded by the SDC1 gene
In Len/Dex-Refractory Patients Rawstron AC (May 2006). "Chapter 6: Immunophenotyping of plasma cells". Current Protocols in Cytometry. Vol. Chapter 6.
Syndecan_1
Blood test
accurate classification. In these cases, other techniques such as immunophenotyping by flow cytometry or special staining can be used to definitively
White_blood_cell_differential
Mass cytometry application to quantify labeled cell targets
important information at a single cell level about protein expression, immunophenotype, and functional characterization. It is a valuable tool in immunology
CyTOF
Medical condition
PN (2009). "Acute Myeloid Leukemia". Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches. Academic Press. p. 236.
Acute_erythroid_leukemia
Diagnostic Serology and Polymerase Chain Reaction (PCR) Viral Load, Immunophenotyping and Peripheral Blood Mononuclear Cell (PBMC) processing, including
Makerere University Walter Reed Project
Makerere_University_Walter_Reed_Project
Category of disease affecting dogs
tissues and perivascular interstitial DC in other involved tissues. Immunophenotyping and careful morphological assessment should also avoid confusion of
Canine_histiocytic_diseases
Human protein
PMID 17715699. Genega EM, Hutchinson B, Reuter VE, Gaudin PB (November 2000). "Immunophenotype of high-grade prostatic adenocarcinoma and urothelial carcinoma". Mod
Prostatic_acid_phosphatase
Aziz, Syed A (ed.). "Contribution of Multiparameter Flow Cytometry Immunophenotyping to the Diagnostic Screening and Classification of Pediatric Cancer"
Flow_cytometry_bioinformatics
Rare type of breast cancer
Kuroda H, Tamaru J, Sakamoto G, Ohnisi K, Itoyama S (January 2005). "Immunophenotype of lymphocytic infiltration in medullary carcinoma of the breast".
Medullary_breast_carcinoma
Medical condition
mast cell markers Reticulin/ collagen stains for fibrosis T-cell immunophenotyping through flow cytometry to detect abnormal T-cell phenotypes Myeloid
Acute_eosinophilic_leukemia
Bioinformatics approaches to immunology
Zlatko (2017-01-03). "Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade". Cell
Computational_immunology
Scientist
Society for Immunology and Wellcome Trust Infection, Immunity and Immunophenotyping. Lloyd studies the lung cells of children who suffer from asthma and
Clare_Lloyd
Precursor cell to a promegakaryocyte in the bone marrow
ISBN 978-93-5090-184-7. Naeim F (2018). Atlas of hematopathology: morphology, immunophenotype, cytogenetics, and molecular approaches (2nd ed.). Waltham, MA: Elsevier
Megakaryoblast
Medical condition
of visual acuity. There are three variants of MCD characterized by immunophenotype:[citation needed] Type 1: no detectable keratan sulfate in either the
Macular_corneal_dystrophy
Medical condition
Wayne W. Grody; Naeim, Faramarz (2008). Hematopathology: morphology, immunophenotype, cytogenetics, and molecular approaches. Amsterdam: Elsevier/Academic
Chronic myelomonocytic leukemia
Chronic_myelomonocytic_leukemia
Immortalized cell line
cytoplasm with large number of granules. They also represent similar immunophenotype to the primary leukemia cells (CD2+, sCD3−, CD7+, CD8+, CD56+ and HLA-DR+)
KHYG-1
Protein-coding gene in humans
with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells". Clin Cancer Res. 11 (4): 1372–9. doi:10.1158/1078-0432
CEBPA
American physician
DL, Hovey KM, Wende KE, Bell DS, Warner CL (May 2003). "Predictive immunophenotypes: disease-related profile in chronic fatigue syndrome". Cytometry Part
David_Sheffield_Bell
Human disease
Chapter 8 - Myelodysplastic Syndromes in Hematopathology Morphology, Immunophenotype, Cytogenetics and Molecular Approaches. pp. 129–154. doi:10.1016/B978-0-12-370607-2
Chromosome 5q deletion syndrome
Chromosome_5q_deletion_syndrome
Williamson, P.; Cortese, I.; Bielekova, B. (2014). "Comprehensive Immunophenotyping of Cerebrospinal Fluid Cells in Patients with Neuroimmunological Diseases"
Biomarkers of multiple sclerosis
Biomarkers_of_multiple_sclerosis
Protein-coding gene in humans
2013.06.022. PMC 3717207. PMID 23870131. "Infection and Immunity Immunophenotyping (3i) Consortium".[permanent dead link] "MARRVEL: Search Result". marrvel
TCF7L2
Tumour cells on blood smear
immunohistochemistry techniques can help determine the lineage of the cells. When immunophenotyped by flow cytometry, the cells are generally CD45 negative and may express
Carcinocythemia
Medical condition
often with admixed necrosis, and a perivascular growth pattern. The immunophenotype is rather characteristic, as the neoplastic cells express renin, CD34
Juxtaglomerular_cell_tumor
American physician
introduced, innovated or enabled: T Lymphocyte counting in HIV disease Immunophenotyping in cancer Flow cytometry analysis in auto-immunity Ultra-short needles
Ken_Strauss
Medical condition
insulitis. This lack of consensus exists because there are many different immunophenotyping markers and cell infiltrate thresholds used to distinguish insulitis
Insulitis
Medical condition
Murata Y, Kodama T, Nagai K, Ochiai A (May 2006). "Comparison of the immunophenotypes of signet-ring cell carcinoma, solid adenocarcinoma with mucin production
Mucinous cystadenocarcinoma of the lung
Mucinous_cystadenocarcinoma_of_the_lung
Type of fully automated microscopy
(March 2006). "Iterative restaining as a pivotal tool for n-color immunophenotyping by slide-based cytometry". Cytometry Part A. 69A (3): 127–130. doi:10
Imaging_cycler_microscopy
Overview of and topical guide to immunology
protein C resistance test Other Blood film Blood viscosity Hematology analyzer Nitro blue tetrazolium chloride test Flow cytometry Immunophenotyping
Outline_of_immunology
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING
Girl/Female
Hindu, Indian
Rain
Girl/Female
Tamil
Girl/Female
Tamil
Saijayani | ஸைஜயாநீ
Personification of victory, A name of shirdi Sai baba
Boy/Male
Hindu
Surrender, Injuring
Male
French
French name derived from Late Latin Ægidius, GILLES means "shield of goatskin."
Male
Hebrew
 Compare with feminine Addie. Pet form of Hebrew Adam, ADDIE means "earth" or "red." Variant spelling of Hebrew unisex Adi, meaning "my ornament" or "my witness."
Girl/Female
Hindu
Passing clouds
Girl/Female
Hindu, Indian
Reddish Brown Cow
Boy/Male
Sikh
God, The loving caretaker
Boy/Male
Muslim/Islamic
Affection
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING
IMMUNOPHENOTYPING