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INTEGRON

  • Integron
  • Feature of bacterial genomes

    Integrons are genetic mechanisms that allow bacteria to adapt and evolve rapidly through the stockpiling and expression of new genes. These genes are

    Integron

    Integron

  • Gene cassette
  • Type of mobile genetic element

    approximately 500–1,000 base pairs. They may exist incorporated into an integron or freely as circular DNA. Gene cassettes can move around within an organism's

    Gene cassette

    Gene_cassette

  • Beta-lactamase
  • Class of enzymes

    IMP. Enzymes of both the families, nevertheless, are similar. Both are integron-associated, sometimes within plasmids. Both hydrolyse all β-lactams except

    Beta-lactamase

    Beta-lactamase

    Beta-lactamase

  • KORE Wireless
  • American telecommunications company

    [citation needed] In December 2019, KORE announced its acquisition of Integron, an IoT solutions and managed services provider. In October 2021, KORE

    KORE Wireless

    KORE Wireless

    KORE_Wireless

  • Protein engineering
  • Bioengineering process

    site specific recombination system in E. coli. This system is called the integron system, and produces natural gene shuffling. This method was used to construct

    Protein engineering

    Protein_engineering

  • SRNA-Xcc1
  • Family of trans-acting non-coding RNA

    gene cassette in the integron of Xanthomonas campestris pv. campestris and homologs of sRNA-Xcc1 are frequently found in integron gene cassettes cloned

    SRNA-Xcc1

    SRNA-Xcc1

  • Vim
  • Topics referred to by the same term

    metrology (VIM, for the French Vocabulaire international de métrologie) Verona integron-encoded metallo-β-lactamase (VIM), a type of Beta-lactamase enzyme Ventral

    Vim

    Vim

  • Morganella morganii
  • Species of bacterium

    Rojas, L; Vinuesa, T; Tubau, F; Truchero, C; Benz, R; Viñas, M (2006). "Integron presence in a multiresistant Morganella morganii isolate". International

    Morganella morganii

    Morganella morganii

    Morganella_morganii

  • INTEGRALL
  • Biological database

    integrons and all other transposable elements that confer resistance to antibiotics in bacteria. As of release 1.2, Integrall contains ~4800 integron

    INTEGRALL

    INTEGRALL

  • Carbapenem-resistant enterobacteriaceae
  • Antibiotic-resistant bacteria

    ineffective. Both of these enzymes, as well as the enzyme VIM (Verona Integron-Mediated Metallo-β-lactamase) have also been reported in Pseudomonas.

    Carbapenem-resistant enterobacteriaceae

    Carbapenem-resistant_enterobacteriaceae

  • Horizontal gene transfer
  • Transfer of genes from unrelated organisms

    insertion sequences/transposons, integrative conjugative elements (ICE), and integrons. Still, they are more frequently a chromosomal-encoded barrier to MGE

    Horizontal gene transfer

    Horizontal gene transfer

    Horizontal_gene_transfer

  • Steve Negron
  • American politician

    Lockheed Martin and General Dynamics before founding his own contracting firm Integron LLC in 2005. He was first elected as a Republican to the New Hampshire

    Steve Negron

    Steve Negron

    Steve_Negron

  • LexA repressor
  • Prokaryotic protein

    factors and antibiotic resistance determinants, as well as the activation of integron integrases, potentially increasing the likelihood of acquisition and dissemination

    LexA repressor

    LexA repressor

    LexA_repressor

  • Mobile genetic elements
  • DNA sequence whose position in the genome is variable

    memory of past transposon activity, and RNA-induced epigenetic silencing. Integrons: These are gene cassettes that usually carry antibiotic resistance genes

    Mobile genetic elements

    Mobile genetic elements

    Mobile_genetic_elements

  • DUF1874 RNA motif
  • RNA family

    sites as part of an integron, as attC sites occur in integrons between a run of consecutive genes that have been taken up by the integron. attC sites are

    DUF1874 RNA motif

    DUF1874 RNA motif

    DUF1874_RNA_motif

  • Artificial tears
  • Eye drops for relieving dryness and irritation in the eye

    after reports of bacterial contamination. A multi-state cluster of Verona Integron-mediated Metallo-β-lactamase (VIM)- and Guiana-Extended Spectrum-β-Lactamase

    Artificial tears

    Artificial tears

    Artificial_tears

  • Pseudomonas aeruginosa
  • Species of bacterium

    whereas the clustering of several different antibiotic resistance genes in integrons favors the concerted acquisition of antibiotic resistance determinants

    Pseudomonas aeruginosa

    Pseudomonas aeruginosa

    Pseudomonas_aeruginosa

  • Integrase
  • Class of enzymes

    elvitegravir, was approved in the U.S. in August 2012. Integrase inhibitor Integron Beck BJ, Freudenreich O, Worth JL (2010). "Patients with Human Immunodeficiency

    Integrase

    Integrase

    Integrase

  • Pseudomonas
  • Genus of Gram-negative bacteria

    whereas the clustering of several different antibiotic resistance genes in integrons favours the concerted acquisition of antibiotic resistance determinants

    Pseudomonas

    Pseudomonas

    Pseudomonas

  • Glossary of cellular and molecular biology (0–L)
  • cell signaling pathways. Contrast integral monotopic protein. integration integron A mobile genetic element consisting of a gene cassette containing the gene

    Glossary of cellular and molecular biology (0–L)

    Glossary_of_cellular_and_molecular_biology_(0–L)

  • Poribacteria-1 RNA motif
  • RNA family

    on the level of single-stranded DNA as attC sites that are part of an integron. It is also possible that Poribacteria-1 RNAs are cis-regulatory elements

    Poribacteria-1 RNA motif

    Poribacteria-1 RNA motif

    Poribacteria-1_RNA_motif

  • Acinetobacter
  • Genus of bacteria

    Tian, B; Xu, H; Li, J (2011). "Detection of OXA-type carbapenemases and integrons among carbapenem-resistant Acinetobactor baumannii in a Teaching Hospital

    Acinetobacter

    Acinetobacter

    Acinetobacter

  • Transposable element
  • DNA sequence that jumps/transposes within a genome

    the ability to transpose to conjugative plasmids. Some TEs also contain integrons, genetic elements that can capture and express genes from other sources

    Transposable element

    Transposable element

    Transposable_element

  • 2022–2023 United States P. aeruginosa outbreak in eye drops
  • outbreak is caused by a strain of Pseudomonas aeruginosa known as Verona Integron-mediated Metallo-β-lactamase (VIM) and Guiana-Extended Spectrum-β-Lactamase

    2022–2023 United States P. aeruginosa outbreak in eye drops

    2022–2023_United_States_P._aeruginosa_outbreak_in_eye_drops

  • Lacticaseibacillus casei
  • Species of bacterium

    Lactobacillaceae transfer. This includes insertion sequences, bacteriophages, integrons, plasmids, genomic islands, and transposons. In lactobacilli, they are

    Lacticaseibacillus casei

    Lacticaseibacillus casei

    Lacticaseibacillus_casei

  • Antimicrobials in aquaculture
  • horizontal gene transfer among microbial populations through plasmids, integrons, and transposons, enabling resistance genes to persist long after antimicrobial

    Antimicrobials in aquaculture

    Antimicrobials_in_aquaculture

  • Transposase
  • Enzyme that catalyzes movement of transposable elements

    up the transposition machinery. In addition, the transposon contains an integron, a DNA segment containing several cassettes of genes encoding for antibiotic-resistance

    Transposase

    Transposase

  • Aspergillomarasmine A
  • Chemical compound

    proteins in bacteria, New Delhi metallo-beta-lactamase 1 (NDM-1) and Verona integron-encoded metallo-beta-lactamase (VIM-2), and make those antibiotic-resistant

    Aspergillomarasmine A

    Aspergillomarasmine A

    Aspergillomarasmine_A

  • AAC/AAD leader
  • Disputed genetic element

    which is a previously known part of integrons and is a signal for recombination, a frequent process in integrons. The letter further stated, among other

    AAC/AAD leader

    AAC/AAD_leader

  • Flaviflexus equikiangi
  • Species of bacterium

    isolated from faeces of Equus kiang (Tibetan wild ass) and carrying a class 1 integron gene cassette in its genome". Journal of Microbiology. 60 (6): 585–593

    Flaviflexus equikiangi

    Flaviflexus_equikiangi

  • Ruth Hall (microbiologist)
  • Australian microbiologist

    larger, stable genetic backbones called integrons that are responsible for moving the cassettes. The integron is also responsible for expression of the

    Ruth Hall (microbiologist)

    Ruth_Hall_(microbiologist)

  • Acinetobacter baumannii
  • Species of bacterium

    clinical and the environmental isolates via the plasmid group GR6 or class 1 integrons through in vitro conjugation. In collaboration with some other genes,

    Acinetobacter baumannii

    Acinetobacter baumannii

    Acinetobacter_baumannii

  • Bharwara Sewage Treatment Plant
  • clinically relevant MDR bacterial strains co-occurrence of ESBL genes and integron-integrase genes". Journal of Environmental Management. 351. Bibcode:2024JEnvM

    Bharwara Sewage Treatment Plant

    Bharwara_Sewage_Treatment_Plant

  • Xanthomonas sRNA
  • Tang DJ, Jiang RP, He YQ, Jiang BL, Lu GT, et al. (2011). "sRNA-Xcc1, an integron-encoded transposon- and plasmid-transferred trans-acting sRNA, is under

    Xanthomonas sRNA

    Xanthomonas_sRNA

  • Human Microbiome Project
  • Former research initiative

    diseases are widespread in normal human subjects and carry extremely diverse integron gene cassettes". Applied and Environmental Microbiology. 78 (15): 5288–96

    Human Microbiome Project

    Human Microbiome Project

    Human_Microbiome_Project

  • Toxin-antitoxin system
  • Biological process

    cholerae, multiple type II toxin-antitoxin systems located in a super-integron were shown to prevent the loss of gene cassettes. mazEF, a toxin-antitoxin

    Toxin-antitoxin system

    Toxin-antitoxin system

    Toxin-antitoxin_system

  • Plasmid-mediated resistance
  • Antibiotic resistance caused by a plasmid

    chromosome by means of recombination systems. Examples of such systems include integrons, transposons, and ISCR-promoted gene mobilization. Most of the resistance

    Plasmid-mediated resistance

    Plasmid-mediated resistance

    Plasmid-mediated_resistance

  • Christopher J. Schofield
  • British chemist

    Çiçek, Ayşegül Ç; Sandalli, Cemal (1 March 2016). "Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability

    Christopher J. Schofield

    Christopher_J._Schofield

  • North Sichuan Medical College
  • Medical school in Sichuan, China

    the multidrug efflux pump genes, adeABC, adeDE and adeIJK, and class 1 integron genes in multiple-antimicrobial-resistant clinical isolates of Acinetobacter

    North Sichuan Medical College

    North_Sichuan_Medical_College

  • Ivan Erill
  • Spanish computational biologist

    dissemination of resistance genes by inducing lateral gene transfer mediated by integrons and other mobile genetic elements. Ivan Erill publications indexed by

    Ivan Erill

    Ivan Erill

    Ivan_Erill

  • Restriction modification system
  • Defense system in bacteria and archaea

    insertion sequences/transposons, integrative conjugative elements (ICEs) and integrons. However, it was recently found that there are relatively few R-M systems

    Restriction modification system

    Restriction modification system

    Restriction_modification_system

  • Geomicrobiology
  • Intersection of microbiology and geology

    resistance, as mobile genetic elements like plasmids, transposons, and integrons carry metal resistance genes (MRGs) between bacterial species. This allows

    Geomicrobiology

    Geomicrobiology

    Geomicrobiology

  • Alpha-D-phosphohexomutase superfamily
  • Superfamily of enzymes

    resistance in clinical isolates of Stenotrophomonas maltophilia: roles of integrons, efflux pumps, phosphoglucomutase (SpgM), and melanin and biofilm formation"

    Alpha-D-phosphohexomutase superfamily

    Alpha-D-phosphohexomutase superfamily

    Alpha-D-phosphohexomutase_superfamily

  • List of MeSH codes (G06)
  • 200 – dna transposable elements MeSH G06.184.603.080.708.330.200.500 – integrons MeSH G06.184.603.080.708.330.330 – genomic islands MeSH G06.184.603.080

    List of MeSH codes (G06)

    List_of_MeSH_codes_(G06)

  • Helitron (biology)
  • Type of transposable element

    recombination model which is based on the shared features between Helitrons and Integrons; Transposable element capture which is based on the integration of TEs

    Helitron (biology)

    Helitron_(biology)

  • Shigella flexneri
  • Species of bacterium

    Liu KZ (August 2006). "Molecular characteristics of class 1 and class 2 integrons and their relationships to antibiotic resistance in clinical isolates

    Shigella flexneri

    Shigella flexneri

    Shigella_flexneri

  • Group II intron
  • Class of self-catalyzing ribozymes

    intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion". Antimicrobial Agents and Chemotherapy. 46 (5):

    Group II intron

    Group II intron

    Group_II_intron

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Online names & meanings

  • T'iis
  • Boy/Male

    Native American

    T'iis

    Cottonwood.

  • Bheemavikra | பிம்வீகரா
  • Boy/Male

    Tamil

    Bheemavikra | பிம்வீகரா

    One of the kauravas

  • Sif
  • Girl/Female

    Norse

    Sif

    Thor's second wife.

  • Blakey
  • Boy/Male

    American, Anglo, British, English

    Blakey

    Dark Complexioned; Blond

  • Qazim
  • Boy/Male

    Arabic, Australian, Muslim

    Qazim

    The One who Imprison his Anger

  • TORA
  • Female

    Hebrew

    TORA

    (תּוֹרָה) Hebrew name TORA means "bible, holy scripture." Compare with another form of Tora.

  • Neeham
  • Boy/Male

    Hindu

    Neeham

    Comfort

  • Aakaksha
  • Girl/Female

    Hindu, Indian, Marathi, Tamil

    Aakaksha

    Desire

  • Sundarbir
  • Boy/Male

    Indian, Punjabi, Sikh

    Sundarbir

    Attractive and Brave

  • WILKIE
  • Male

    Scottish

    WILKIE

    Pet form of Scottish Gaelic Uilleam, WILKIE means "will-helmet." 

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