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Rare genetic disorder
Lesch–Nyhan syndrome (LNS) is a rare genetic disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This
Lesch–Nyhan_syndrome
Surname list
Henry Lesch, American businessman Harald Lesch, German physicist John Lesch, American politician Karin Lesch, Swiss-German actress Klaus-Peter Lesch, German
Lesch
German physicist
Harald Lesch (born 28 July 1960) is a German physicist, astronomer, natural philosopher, author, television presenter, professor of physics at LMU Munich
Harald_Lesch
American physician (1939–2008)
Michael Lesch (June 30, 1939 – March 19, 2008) was an American physician and medical educator who helped identify an important genetic disorder associated
Michael_Lesch
German alpine skier (born 1942)
Slalom, and Men's Slalom. Willi Lesch at Olympics at Sports-Reference.com (archived) Willi Lesch at Olympedia Willi Lesch at InterSportStats Portals: Biography
Willi_Lesch
American politician (born 1973)
John Lesch (born January 15, 1973) is a Minnesota politician and former member of the Minnesota House of Representatives. A member of the Minnesota
John_Lesch
German tennis player
Andreas Lesch (born 4 January 1966) is a former professional tennis player from Germany. Titles and achievements: 1984 North-Rhine-Westfalen state championships
Andreas_Lesch
German clinical psychiatrist
Klaus-Peter Lesch is a German clinical psychiatrist who has been investigating the neurobiological foundation of personality traits. His 1996 paper on
Klaus-Peter_Lesch
German singer-songwriter (born 1986)
Sarah Lesch (born 1 March 1986) is a German singer-songwriter who performs with a guitar and ukulele. Lesch was born in Altenburg, Thuringia and moved
Sarah_Lesch
Swiss-German stage, film and television actress (1935–2025)
Karin Lesch (18 May 1935 – 12 March 2025) was a Swiss-German stage, film, and television actress, of Swiss-Austrian extraction; who hailed from a multi-generational
Karin_Lesch
Danish businessman and tennis player (born 1940)
Jan Leschly (born 11 September 1940) is a Danish businessman and former professional tennis player. He was a semifinalist in the men's singles at the
Jan_Leschly
American fiber artist (1917–1999)
Alma Lesch (March 12, 1917 – May 15, 1999) was an American fiber artist known for her fiber portraits. She was "the undisputed grande dame of Kentucky
Alma_Lesch
German middle-distance runner
Gabriela Katharina "Gabi" Lesch (born 17 August 1964) is a retired German runner who specialized in the 800 metres. She represented West Germany at the
Gabriela_Lesch
South African soccer player
Keenin Lesch (born 13 March 1981) is a South African association football midfielder who has coached National First Division club Vasco da Gama. "Keenin
Keenin_Lesch
American Catholic educator, director, musical conductor (1924–1983)
Carl William Lesch (1924–1983) was an American Catholic educator, director, and musical conductor and instructor associated with many institutions in
Carl_Lesch
Lecturer and commentator on Middle East politics
David Warren Lesch is a lecturer, author and commentator on Middle East history and politics. He is the Ewing Halsell Distinguished Professor of Middle
David_W._Lesch
Compulsion towards biting one's own skin
Autocannibalism Body-focused repetitive behavior Excoriation disorder Lesch–Nyhan syndrome Pica Grzesiak, Magdelena; Pacan, Przemysław; Reich, Adam;
Dermatophagia
Swiss stage and movie producer-director and writer
Walter Lesch (4 March 1898 – 27 May 1958) was a Swiss stage and movie producer-director. He was also a writer and, for nearly twenty years after 1933
Walter_Lesch
George Henry Lesch (1909–1994) was the president and CEO of the Colgate-Palmolive company from 1961 to 1974, and was also the chairman of the board of
George_Henry_Lesch
French botanist and ornithologist (1773-1826)
of Leschenault, and Lake Leschenaultia. The standard author abbreviation Lesch. is used to indicate this person as the author when citing a botanical name
Jean-Baptiste Leschenault de La Tour
Jean-Baptiste_Leschenault_de_La_Tour
Genus of plants
investigation. At present the accepted taxonomy is as follows: Antiaris toxicaria Lesch. Antiaris toxicaria var. africana Scott Elliot ex A.Chev. (synonyms Antiaris
Antiaris
Neurodevelopmental disorder
Neurology. 16 (5): 422–433. doi:10.1016/j.ejpn.2012.01.009. PMID 22306277. Lesch KP, Merker S, Reif A, Novak M (June 2013). "Dances with black widow spiders:
Attention deficit hyperactivity disorder
Attention_deficit_hyperactivity_disorder
American physician (1926–2026)
11, 2026) was an American physician best known as the co-discoverer of Lesch–Nyhan syndrome. Nyhan later served as professor of pediatrics at University
William_Nyhan
American physician
geneticist best known for his role in discovering the biochemical basis of the Lesch–Nyhan syndrome. He was a rheumatologist and a pioneer in research on arthritic
J._Edwin_Seegmiller
Organic compound
or allopurinol to inhibit purine catabolism from adding to uric acid levels. Lesch–Nyhan syndrome, a rare inherited disorder, is also associated with high
Uric_acid
115. Lesch 1994, p. 140. Lesch 1994, p. 141. Lesch 1994, p. 156. Lesch 1994, pp. 144–145. Lesch 1994, p. 145. Lesch 1994, pp. 145–146. Lesch 1994, p
1986 Sudanese parliamentary election
1986_Sudanese_parliamentary_election
1990–1991 conflict in the Middle East
Crisis. John Wiley & Sons. pp. 161-162. ISBN 978-0-471-54299-5. Stork, Joe; Lesch, Ann M. (1990). "Background to the Crisis: Why War?". Middle East Report
Gulf_War
Enzyme that converts hypoxanthine to inosine monophosphate
urinary tract. This condition has been named the Kelley–Seegmiller syndrome. Lesch–Nyhan syndrome is due to deficiency of HGPRT caused by HPRT1 mutation. Some
Hypoxanthine-guanine phosphoribosyltransferase
Hypoxanthine-guanine_phosphoribosyltransferase
Group of physical problems resulting from basal ganglia dysfunction
and globus pallidus, responsible for motivation and executive functions. Lesch–Nyhan syndrome is a rare X-linked recessive disorder caused by a deficiency
Basal_ganglia_disease
American dental hygiene brand
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Colgate_(toothpaste)
Brand of toothpaste
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Elmex
Species of plant
19 synonyms Guatteria macrantha C.Presl Unona grandiflora Lesch. ex DC. Uva grandiflora (Lesch. ex DC.) Kuntze Uvaria cardinalis Elmer Uvaria flava Teijsm
Uvaria_grandiflora
Danish footballer (1922–1999)
Jørgen Leschly Sørensen (24 September 1922 – 21 February 1999) was a Danish footballer who played as a forward. He started as an amateur player in Danish
Jørgen_Leschly_Sørensen
Deodorant sold by Colgate-Palmolive
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Teen_Spirit_(deodorant)
German documentary TV series brand
documentaries and clips on platforms like YouTube. The Terra X Lesch & Co channel presented by Harald Lesch was launched on 3 February 2016. Later that year, their
Terra_X
Habit and impulse disorder
Magazine. Retrieved May 11, 2025. Nanagiri, Apoorva; Shabbir, Nadeem (2022). Lesch Nyhan Syndrome. Treasure Island, Florida: StatPearls [Internet]. PMID 32310539
Compulsive_behavior
Emigration during and after the Gulf War
in Kuwait. 1948 Palestinian expulsion and flight 1991 uprisings in Iraq Lesch, Ann M. (2005). "Kuwait". In Mattar, Philip (ed.). Encyclopedia of the Palestinians
Expulsion of Palestinians from Kuwait (1990–91)
Expulsion_of_Palestinians_from_Kuwait_(1990–91)
Pet food company
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Hill's_Pet_Nutrition
American brand of hygiene products
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Palmolive_(brand)
American businessman and Christian leader
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Ed_McAteer
Involuntary utterance of socially inappropriate words
other neurological conditions such as choreoacanthocytosis, seizures, and Lesch–Nyhan syndrome; and rarely in persons with dementia or obsessive-compulsive
Coprolalia
Business magnate
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
William_Colgate
Historic site in Clarksville, Indiana
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Colgate_Clock_(Indiana)
Hartmut Griesmayr [de] Ursula Buschhorn [de], Bernhard Schir [de], Michael Lesch [de], Herbert Fux Drama A Pass from the Back [de] Gil Mehmert [de] Arndt
List of German films of the 2000s
List_of_German_films_of_the_2000s
Brand of toothpaste
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Darlie
American manufacturer of personal care products
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Tom's_of_Maine
Tics in the absence of Tourette syndrome
trauma, encephalitis, stroke, and carbon monoxide poisoning. The symptoms of Lesch–Nyhan syndrome may also be confused with Tourette syndrome. Chorea (disease)
Tourettism
American cleaning product brand
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Murphy_Oil_Soap
Danish officer and equestrian
Niels Erik Leschly (23 February 1910 – 2 November 1986) was a Danish equestrian. He competed in two events at the 1936 Summer Olympics. Evans, Hilary;
Niels_Erik_Leschly
1985-1992 German television series
1985 to 1992, starring Siegfried Wischnewski, Marion Kracht, and Michael Lesch. It was first on the air January 23, 1985, and the last episode aired March
Ein_Heim_für_Tiere
Species of flowering plant
junghuhniana Miq. Subspecies C. j. subsp. junghuhniana C. j. subsp. timorensis Synonyms Casuarina montana Lesch. ex Miq. Casuarina muricata Roxb. ex Hornem.
Casuarina_junghuhniana
The Day of the Storm [de] Helmut Förnbacher Sophie von Kessel, Michael Lesch [de], Rolf Hoppe, Horst-Günter Marx [de], Heidelinde Weis Drama a.k.a. Stürmische
List of German films of the 1990s
List_of_German_films_of_the_1990s
Genus of plants in the myrtle family
Species See List of Melaleuca species Synonyms Genus synonymy Baudinia Lesch. ex DC. Beaufortia R.Br. in W.T.Aiton Billottia Colla Callistemon R.Br.
Melaleuca
Soap liquid detergent by Colgate-Palmolive
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Vel_Soap
Austrian actress (1903–1988)
Leusch; Leusch is apparently a variant of her second husband's surname (Lesch). Mathilde Danegger was born and attended school in Vienna. Her father was
Mathilde_Danegger
1998 thriller novel by Richard Preston
that results from the virus, brainpox, has symptoms that mimic those of Lesch–Nyhan syndrome and the common cold. The book is divided between descriptions
The_Cobra_Event
Genus of flowering plants
Chaowasku & Kessler Miliusa horsfieldii (Benn.) Baill. ex Pierre Miliusa indica Lesch. ex A.DC. Miliusa intermedia Chaowasku & Kessler Miliusa koolsii (Kosterm
Miliusa
American brand of deodorant soap
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Irish_Spring
President of Syria from 2000 to 2024
Bashar's Trial By Fire. Brookings Institution. ISBN 978-0-8157-5204-2. Lesch, David W. (2011). Syria: The Fall of the House of Assad. Yale University
Bashar_al-Assad
Self-biting &/or devouring portions of one's own body
obsessive compulsive disorder, borderline personality disorder, anxiety, and Lesch-Nyhan Syndrome. Medical research has displayed the presence of autophagia
Autophagia
Medium of exchange
Akerson Charlene Barshefsky Ursula Burns Peter Chernin Vernon Jordan Jr. Jan Leschly Richard C. Levin Edward D. Miller Frank Popoff Robert D. Walter Ron Williams
Traveller's_cheque
Indian oral hygiene brand
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Cibaca_(brand)
American abolitionist (1818–1895)
developed his own political views. Charles H. T. Lesch has shown that Douglass created a theory, which Lesch calls "natural rights from below", based on the
Frederick_Douglass
British businessman
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Ian_M._Cook
Carsten Jensen Josef Joffe Walter Kempowski Ross King David Lama Harald Lesch Pascal Mercier Philipp Meyer Walter Moers Irène Némirovsky Lawrence Norfolk
Albrecht_Knaus_Verlag
Czechoslovak tennis player
Christian Saceanu Alex Antonitsch Brian Levine 3–6, 6–1, 7–6 2. 1988 Heilbronn, West Germany Carpet Udo Riglewski Axel Hornung Andreas Lesch 7–6, 4–6, 6–2
Jaromir_Becka
German pornographic film director
in Essen. In 1991, he directed the thriller Pommes Rot-Weiß with Michael Lesch. His first actions as a director and producer in the porn industry were
Harry_S._Morgan
American toothpaste brand
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Ultra_Brite
2010 studio album by Crown of Creation
August 18, 2010, and produced by Adrian Lesch. "Darkness in Your Life" was written by Anne Crönert and Adrian Lesch. "Run away" is written by Sabine Mertens
Darkness_in_Your_Life
Species of flowering plant
Binomial name Senecio candicans Wall. ex DC. Synonyms Senecio candidans Wall. Senecio campylodes var. candicans C.B.Cl. Cineraria sarmentosa Lesch. ex DC.
Senecio_candicans
American deodorant brand
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Mennen
Investigational dopamine antagonist
is a dopamine antagonist which is under development for the treatment of Lesch–Nyhan syndrome, Tourette syndrome, speech disorders, and restless legs syndrome
Ecopipam
Village in Illinois, United States
gasoline-powered car Clifford C. Ireland, U.S. congressman, 1917–1923 George Henry Lesch, CEO of Colgate-Palmolive (1960–1971) "2022 U.S. Gazetteer Files: Illinois"
Washburn,_Illinois
Brand of cleaning products
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Ajax_(cleaning_product)
American policy on the Middle East
Doctrine of 1957." Presidential Studies Quarterly 36.1 (2006): 38–47. online Lesch, David W. "The 1957 American–Syrian Crisis: Globalist Policy in a Regional
Eisenhower_Doctrine
1850–2008 American financial services firm
Akerson Charlene Barshefsky Ursula Burns Peter Chernin Vernon Jordan Jr. Jan Leschly Richard C. Levin Edward D. Miller Frank Popoff Robert D. Walter Ron Williams
Lehman_Brothers
American actress (1917–2004)
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Jan_Miner
Species of flowering plant
name Phoenix canariensis H.Wildpret Synonyms Phoenix jubae (Webb & Berthel.) Webb ex Christ Phoenix senegalensis Lesch. ex André Phoenix vigieri Naudin
Phoenix_canariensis
CEO of American Express
Akerson Charlene Barshefsky Ursula Burns Peter Chernin Vernon Jordan Jr. Jan Leschly Richard C. Levin Edward D. Miller Frank Popoff Robert D. Walter Ron Williams
Stephen_Squeri
German political activist (1911–2003)
activist Resistance activist Party official University teacher Political party KPD SED PDS Spouse Mathilde Danegger Children Karin Lesch (step daughter)
Herbert_Crüger
Trade name of Colgate-Palmolive's liquid hand soap & body wash
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Softsoap
American advertising clock facing the Hudson River
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Colgate_Clock_(Jersey_City)
Brand of soap
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Protex_(soap)
Synthetic dye
Perspectives. 49: 13–19. doi:10.1289/ehp.834913. PMC 1569142. PMID 6339220. John E Lesch, The First Miracle Drugs: How the Sulfa Drugs Transformed Medicine (New
Mauveine
Intentional injury to one's body
behaviour in Lesch-Nyhan syndrome". Journal of Oral Pathology and Medicine. 34 (9): 573–575. doi:10.1111/j.1600-0714.2005.00330.x. PMID 16138897. "Lesch-Nyhan
Self-harm
13th R16 Marek Seruga Timo Lesch 8 1997-98 Regionalliga Nordost (3) 34 12 7 15 55 55 0 43 11th QF Bernd Jopek Timo Lesch Sebastian Müller 14 12 11 1998-99
List of Berliner FC Dynamo seasons
List_of_Berliner_FC_Dynamo_seasons
persistence (dominant) Leber's hereditary optic neuropathy[citation needed] Lesch–Nyhan syndrome Marfan syndrome Niemann–Pick disease[citation needed] Phenylketonuria
Mendelian_traits_in_humans
American diplomat
1960, and was the subject of a book by Paul Lesch [lb] titled Playing Her Part: Perle Mesta in Luxembourg. Lesch also directed a documentary film about Mesta's
Perle_Mesta
American multinational consumer products company
last show As the World Turns was canceled in September 2010. George Henry Lesch, president, CEO, and chairman of the board of Colgate-Palmolive in the 1960s
Colgate-Palmolive
Mammalian protein found in humans
32–38. doi:10.1038/sj.mp.4000698. PMID 10673766. S2CID 12459610. Murphy DL, Lesch KP (February 2008). "Targeting the murine serotonin transporter: insights
Serotonin_transporter
Palestinian commemoration of 1948 displacement
Solidarity with the Palestinian People Naksa Day Ongoing Nakba David W. Lesch; Benjamin Frankel (2004). History in Dispute: The Middle East since 1945
Nakba_Day
German multinational pharmaceutical and biotechnology company
Scientists: Science, War, and the Devil's Pact. London: Penguin Books. Lesch JE, ed. (2000). The German Chemical Industry in the Twentieth Century. Dordrecht:
Bayer
Neurodevelopmental disorder involving tics
and carbon monoxide poisoning. The extreme self-injurious behaviors of Lesch–Nyhan syndrome may be confused with Tourette syndrome or stereotypies, but
Tourette_syndrome
Process
"The Lesch-Nyhan syndrome". Annual Review of Medicine. 24: 41–60. doi:10.1146/annurev.me.24.020173.000353. PMID 4575865. "Lesch-Nyhan". Lesch-Nyhan.org
Nucleic_acid_metabolism
Period of severe diplomatic confrontations during the Cold War
1992.tb00194.x. Lesch, David W. (1992a). Syria and The United States: Eisenhower's Cold War In The Middle East. Westview Press. Lesch, David W. (1990)
Syrian_Crisis_of_1957
Finnish author and cartoonist (1926–2000)
Svenska Samskola in 1944. From 1961 to 1968, Jansson was married to Anita Lesch. He made a study trip to Spain where he lived from 1962 to 1966. In 1957
Lars_Jansson_(cartoonist)
American brand of baby care products
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
Baby_Magic
Mensa International award
Yogeshwar, a German TV host 2008: Dieter Nuhr, a comedian 2009: Harald Lesch, an astrophysicist and TV host 2010: Spektrum der Wissenschaft, the German
IQ_Award
American CEO and philanthropist
Cahill David Foster Ellen Hancock Martin Ittner Richard Kogan George Henry Lesch Delano Lewis David J. Mahoney Ed McAteer Jan Miner Stephen Sadove Brands
David_J._Mahoney
Office skyscraper in Manhattan, New York
Akerson Charlene Barshefsky Ursula Burns Peter Chernin Vernon Jordan Jr. Jan Leschly Richard C. Levin Edward D. Miller Frank Popoff Robert D. Walter Ron Williams
200_Vesey_Street
travel, tourism, insurance
LESCH
LESCH
LESCH
LESCH
LESCH
LESCH
LESCH
LESCH
LESCH
travel, tourism, insurance