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Branch of proteomics
Phosphoproteomics is a branch of proteomics that identifies, catalogs, and characterizes proteins containing a phosphate group as a posttranslational
Phosphoproteomics
Chemical process of introducing a phosphate
Campbell AE, et al. (October 2019). "Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation". The EMBO Journal
Phosphorylation
Chemical compound in the ergot family of alkaloids
la Cour C, Millan MJ, Prézeau L, et al. (May 2014). "Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280
Ergotamine
Lung disease involving long-term poor airflow
Liang M, Wang X, Lu S, Peng T, Long F (2022-12-02). "Advances in phosphoproteomics and its application to COPD". Expert Review of Proteomics. 19 (7–12):
Chronic obstructive pulmonary disease
Chronic_obstructive_pulmonary_disease
Large-scale study of proteins
are not active until they become phosphorylated. Methods such as phosphoproteomics and glycoproteomics are used to study post-translational modifications
Proteomics
Class of green algae
Halotolerant Algae Dunaliella salina Revealed by Quantitative Proteomics and Phosphoproteomics". Frontiers in Plant Science. 8 810. Bibcode:2017FrPS....8..810W.
Chlorophyceae
Genetically engineered T cell
Raphael; Paulovich, Amanda G.; Riddell, Stanley R. (2018-08-21). "Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and
CAR_T_cell
German physician and biomedical scientist
thrombosis. He and colleagues applied advanced functional proteomics and phosphoproteomics to understand the Kinome (all protein kinases) and their signal transduction
Ulrich Walter (clinical biochemist)
Ulrich_Walter_(clinical_biochemist)
Computational and mathematical modeling of complex biological systems
systems coupled with mass spectrometry). Sub disciplines include phosphoproteomics, glycoproteomics and other methods to detect chemically modified proteins;
Systems_biology
Enzyme which catalyzes the removal of a phosphate group from a molecule
Patrick G.; Gerrits, Bertran; Picotti, Paola; Lam, Henry (2010-12-21). "Phosphoproteomic Analysis Reveals Interconnected System-Wide Responses to Perturbations
Phosphatase
Protein without a fixed 3D structure
Collins MO, Yu L, Campuzano I, Grant SG, Choudhary JS (July 2008). "Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein
Intrinsically disordered proteins
Intrinsically_disordered_proteins
Cumulative effect of not getting enough sleep
J, Yu Y, Funato H, Yanagisawa M, Liu Q (June 2018). "Quantitative phosphoproteomic analysis of the molecular substrates of sleep need". Nature. 558 (7710):
Sleep_debt
Process of introducing a phosphate group on to a protein
phosphorylates A, or phosphorylates protein C. Global approaches such as phosphoproteomics, the study of phosphorylated proteins, which is a sub-branch of proteomics
Protein_phosphorylation
Type of mass spectrometry
J, Olsen JV, Mann M (December 2010). "Feasibility of large-scale phosphoproteomics with higher energy collisional dissociation fragmentation". Journal
Tandem_mass_spectrometry
Protein-coding gene in the species Homo sapiens
Y, Low TY, Choong LY, Ray RS, Tan YL, Toy W, et al. (July 2007). "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation
CEP68
Protein-coding gene in humans
Jensen TS, Nigg EA, Brunak S, Mann M (January 2010). "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis"
FSAF1
high-resolution mass spectrometry instrumentations. Systems biology Phosphoproteomics Tissot B, North SJ, Ceroni A, Pang PC, Panico M, Rosati F, et al.
Glycoproteomics
Protein-coding gene in the species Homo sapiens
Shimobayashi M, Cornu M, Fava LL, Moes S, et al. (March 2013). "Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis". Science. 339
CAD_protein
Chemical compound
G, Gholamin S, Rusert JM, et al. (September 2018). "Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a
Silmitasertib
Protein-coding gene in the species Homo sapiens
1093/molehr/gah066. PMID 15155816. Hinsby AM, Olsen JV, Mann M (2004). "Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor
IRS4
American-Swiss molecular biologist
Christina; Sauer, Uwe; Jenoe, Paul; Hall, Michael N. (2013). "Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis". Science. 339:
Michael_N._Hall
Pharmaceutical compound
McCracken AN, Perryman M, Hanessian S, et al. (March 2019). "Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid
SH-BC-893
Protein-coding gene in the species Homo sapiens
Wong CH, Lim S, Li B, Hew CL, Sze NS, Druker BJ, Lim YP (Jul 2007). "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation
DCBLD2
Protein capable of worsening malignant diseases
PMID 15302935. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
Hepatoma-derived growth factor
Hepatoma-derived_growth_factor
Japanese molecular biologist
Hiromasa; Yanagisawa, Masashi; Liu, Qinghua (2018). "Quantitative phosphoproteomic analysis of the molecular substrates of sleep need". Nature. 558 (7710):
Masashi_Yanagisawa
Hepatitis C virus protein
Yi-Hung; Chang, Justin; Chen, Steve S.-L.; Yu, Ming-Jiun (2016-02-19). "Phosphoproteomics Identified an NS5A Phosphorylation Site Involved in Hepatitis C Virus
Hepatitis C virus nonstructural protein 5A
Hepatitis_C_virus_nonstructural_protein_5A
Mammalian protein found in Homo sapiens
BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
Enamelin
Protein found in humans
Esposito EA, Gridley S, Leitinger B, Naegle KM, Huang PH (July 2013). "Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream
Discoidin domain-containing receptor 2
Discoidin_domain-containing_receptor_2
Protein fragment
phagosomal maturation, inducing a marked alteration in the neutrophil phosphoproteomic response to bacterial targets. C5a binding to C5aR1 and C5aR2 (C5L2)
Complement_component_5a
Cell and developmental biologist
mutation-load skew in multiple cancers.2014 DOI: 10.1098/rsob.140029 Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1
Carol_MacKintosh
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
TNIK
Protein-coding gene in the species Homo sapiens
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
ARVCF
Analytical chemistry technique
Larsen MR (March 2013). "Technologies and challenges in large-scale phosphoproteomics". Proteomics. 13 (6): 910–931. doi:10.1002/pmic.201200484. PMID 23404676
Quantitative_proteomics
Protein-coding gene in the species Homo sapiens
PMID 16565220. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
MFAP1
in virus–host factor interactions. DCP has also collaborated in a phosphoproteomics project designed to study the molecular mechanisms in the pathogenesis
Dundee_Cell_Products
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
FNBP1
Protein-coding gene in the species Homo sapiens
PMID 15057823. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
HSPH1
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
Latrophilin_1
Mammalian protein found in humans
Jaffe H, Moreira JE, Carlotti CG, Leite JP, Pant HC, et al. (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". Journal of Proteome
SV2A
Protein-coding gene in humans
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
PIKFYVE
Protein-coding gene in the species Homo sapiens
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
SOX11
Protein-coding gene in humans
Beranova-Giorgianni S, Zhao Y, Desiderio DM, Giorgianni F (2006). "Phosphoproteomic analysis of the human pituitary". Pituitary. 9 (2): 109–20. doi:10
CAP1
Protein-coding gene in the species Homo sapiens
H, Moreira JE, Carlotti CG, Leite JP, Pant HC, Dosemeci A (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". J. Proteome Res
GABBR2
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
G3BP1
Protein-coding gene in the species Homo sapiens
Jensen TS, Nigg EA, Brunak S, Mann M (January 2010). "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis"
TASOR2
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
SRRM2
Protein-coding gene in the species Homo sapiens
PMID 15342556. DeGiorgis JA, Jaffe H, Moreira JE, et al. (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". J. Proteome Res
NEFM
Kumar C, Miller ML, Jensen LJ, et al. (January 2010). "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis"
RNF113A
Gene of the species Homo sapiens
PMID 14702039. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
Intersectin_2
Protein-coding gene in the species Homo sapiens
PMID 15231748. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
ABRAXAS2
Protein-coding gene in the species Homo sapiens
protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics". Molecular & Cellular Proteomics. 11 (12): 1640–51. doi:10.1074/mcp
SHOC1
Indian-American cardiologist
Anthony P.; Kaul, Sanjiv; Davis, Catherine M. (September 2021). "Phosphoproteomic response of cardiac endothelial cells to ischemia and ultrasound".
Sanjiv_Kaul
Protein found in humans
PMID 14702039. Ballif BA, Villén J, Beausoleil SA, et al. (2004). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
Coiled-coil domain-containing protein 25
Coiled-coil_domain-containing_protein_25
Protein-coding gene in the species Homo sapiens
Jaffe H, Moreira JE, Carlotti CG, Leite JP, Pant HC, et al. (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". Journal of Proteome
TPPP
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
HNRPH1
Protein-coding gene in the species Homo sapiens
Beranova-Giorgianni S, Zhao Y, Desiderio DM, Giorgianni F (2006). "Phosphoproteomic analysis of the human pituitary". Pituitary. 9 (2): 109–20. doi:10
RALY
Protein-coding gene in humans
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
MARCKSL1
Protein-coding gene in the species Homo sapiens
PMID 14702039. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
40S_ribosomal_protein_S17
Protein-coding gene in the species Homo sapiens
BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
NIMA-related_kinase_1
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
RBM3
Protein found in humans
S2CID 13709685. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
Capicua_(protein)
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
BICD2
Protein-coding gene in the species Homo sapiens
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
DDX42
Protein-coding gene in the species Homo sapiens
PMID 15489334. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
PCYT1B
British biological mass spectrometrist
be presenting a series of lectures during 2020 and 2021 focused on phosphoproteomics and post translational modification analysis of proteins.[citation
Claire_E._Eyers
Protein-coding gene in humans
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
CDC23
Protein-coding gene in the species Homo sapiens
PMID 15231748. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
PCDH1
Biological protein kinase C inhibitor
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis". J Proteome Res. 7 (3): 1346–51. doi:10.1021/pr0705441. PMID 18220336
BIM-1
Protein-coding gene in the species Homo sapiens
Y, Low TY, Choong LY, Ray RS, Tan YL, Toy W, et al. (July 2007). "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation
ZFYVE16
Family of enzymes important in cell signaling
phosphorylation in human cells revealed using strong-anion exchange-mediated phosphoproteomics". bioRxiv 10.1101/202820. Marina A, Waldburger CD, Hendrickson WA
Histidine_kinase
Protein-coding gene in the species Homo sapiens
PMID 14613930. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
DCLK1
Protein-coding gene in humans
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
PDE4B
Protein-coding gene in the species Homo sapiens
PMID 15302935. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
NF-kappa-B-activating_protein
Protein-coding gene in the species Homo sapiens
BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
RBM10
Protein-coding gene in the species Homo sapiens
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (2004). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
SAFB2
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
UBAP2
Protein-coding gene in humans
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
FGFR1OP
Protein-coding gene in humans
PMID 15302935. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
NUCKS1
Protein-coding gene in the species Homo sapiens
PMID 12760907. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
LPP_(gene)
Protein-coding gene in the species Homo sapiens
PMID 12954649. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
DLGAP1
Protein-coding gene in the species Homo sapiens
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
FYN-binding_protein_1
Protein-coding gene in the species Homo sapiens
BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
G3BP2
Stem cells
cell biology include: membrane proteomics for cell surface markers, phosphoproteomics for signal transduction, shotgun proteomics for differential protein
Stem_cell_proteomics
Protein-coding gene in the species Homo sapiens
PMID 12624101. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
LATS1
68:1905-1915, 2008) Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle (co-author, MOLECULAR CELL 31:438-448
György_Kéri
Protein-coding gene in humans
Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
KIRREL1
Protein-coding gene in the species Homo sapiens
PMID 15096539. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
DDX3Y
Protein-coding gene in the species Homo sapiens
Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (Nov 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
IRF2BPL
Protein-coding gene in the species Homo sapiens
PMID 14702039. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
REEP1
Protein-coding gene in the species Homo sapiens
PMID 15302935. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
CCAR2
Protein-coding gene in the species Homo sapiens
PMID 15489334. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
LPXN
Canadian Scientist
Spectrometry Feb 2006 Multiple cellular antigen detection by ICP-MS Jan 2006 Phosphoproteomics in Drug Discovery and Development Aug 2004 The Reproducible Acquisition
Olga_Ornatsky
Protein-coding gene in the species Homo sapiens
PMID 15057823. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
ZC3H13
Protein-coding gene in the species Homo sapiens
BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
KCTD12
Protein-coding gene in the species Homo sapiens
PMID 14702039. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
OTUD4
Protein-coding gene in humans
BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics
CCDC88A
Protein-coding gene in humans
H, Moreira JE, Carlotti CG, Leite JP, Pant HC, Dosemeci A (2005). "Phosphoproteomic analysis of synaptosomes from human cerebral cortex". J. Proteome Res
PKN2
Protein-coding gene in the species Homo sapiens
PMID 15302935. Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11):
DYNC1LI1
Protein-coding gene in the species Homo sapiens
S2CID 16522705. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
Sodium bicarbonate cotransporter 3
Sodium_bicarbonate_cotransporter_3
Protein-coding gene in the species Homo sapiens
PMID 14559993. Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using
THRAP3
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