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Medication used to treat hyperthyroidism
Propylthiouracil (PTU) is a medication used to treat hyperthyroidism. This includes hyperthyroidism due to Graves' disease and toxic multinodular goiter
Propylthiouracil
Person with an elevated taste response
heightened response to the suprathreshold bitterness of concentrated propylthiouracil (PROP), the contemporary view supports that supertasting encompasses
Supertaster
Endocrine disease
treatment of thyroid storm is with inorganic iodine and antithyroid drugs (propylthiouracil or methimazole) to reduce synthesis and release of thyroid hormone
Thyroid_storm
Chemical compound
who developed significant side effects may also have problems with propylthiouracil. Thiamazole is a cyclic thiourea derivative that works by decreasing
Thiamazole
Species of plant
receptor that functions as a taste receptor, mediated by ligands such as propylthiouracil (PTU) and phenylthiocarbamide that bind to the receptor and initiate
Brassica_oleracea
Inflammation of small blood vessels, accompanied by skin bumps
Cutaneous small-vessel vasculitis (CSVV) is inflammation of small blood vessels, usually accompanied by small lumps beneath the skin. The condition is
Cutaneous small-vessel vasculitis
Cutaneous_small-vessel_vasculitis
Excessive production of thyroid hormone
the UK) and methimazole (used in the US, Germany, and Russia), and propylthiouracil. Thyrostatics are believed to work by inhibiting the iodination of
Hyperthyroidism
Chemical element with atomic number 53 (I)
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Iodine
Enzyme expressed mainly in the thyroid gland
gene expression. TPO is inhibited by the thioamide drugs, such as propylthiouracil and methimazole. In laboratory rats with insufficient iodine intake
Thyroid_peroxidase
Hormone antagonist acting upon thyroid hormones
antithyroid drugs are carbimazole (in the UK), methimazole (in the US), and propylthiouracil (PTU). A less common antithyroid agent is potassium perchlorate. The
Antithyroid_agent
Autoimmune endocrine disease
effectively after 12 weeks than did propylthiouracil (77.1% on methimazole 15mg vs 19.4% in the propylthiouracil 150mg groups). No difference in outcome
Graves'_disease
Thyroid hormone medication
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Levothyroxine
Endocrine gland in the neck
hyperthyroidism may include drugs that suppress thyroid function such as propylthiouracil, carbimazole and methimazole. Alternatively, radioactive iodine-131
Thyroid
Liver damage caused by a drug or chemical
such as amoxicillin/clavulanic acid. Treatment with methimazole or propylthiouracil for hyperthyroidism, is commonly associated with an elevation of liver
Hepatotoxicity
Pharmaceutical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Elunetirom
Medication used for hyperthyroidism
For those patients where sensitivity reactions cannot be controlled, propylthiouracil may be used as an alternative; cross-sensitivity between these drugs
Carbimazole
Thyroid gland prepared for medical use
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Desiccated_thyroid_extract
Protein-coding gene in the species Homo sapiens
varying genotypes of TAS2R38 influence the ability to taste both 6-n-propylthiouracil (PROP) and phenylthiocarbamide (PTC). Though it has often been proposed
TAS2R38
Substances that disrupt the production of thyroid hormones
shown to have goitrogenic effects include: Sulfadimethoxine (Albon), propylthiouracil, potassium perchlorate, and iopanoic acid. Some oxazolidines such as
Goitrogen
Class of organic compounds
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thioamide
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Resmetirom
Medical condition
carbamazepine and valproate), antithyroid drugs (carbimazole, thiamazole, and propylthiouracil), antibiotics (penicillin, chloramphenicol and trimethoprim/sulfamethoxazole)
Agranulocytosis
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
VK2809
Pharmaceutical drug
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
ASC41
Chemical compound
used antithyroid preparation. It is a thioamide, closely related to propylthiouracil. Methylthiouracil is not used clinically in the United States, it has
Methylthiouracil
Beta blocker drug
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Propranolol
Chemical compound
particularly when they are used as an adjunctive therapy with thioamides (propylthiouracil, carbimazole). They can be used in the treatment of patients with severe
Iopanoic_acid
Formulary by the World Health Organization
Complementary: Diazoxideα Levothyroxine Potassium iodide Methimazole Propylthiouracil Complementary: Iodine + potassium iodide (Lugol's solution)α Methimazoleα
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
Organosulfur compounds with an >NC(=S)N< structure
methimazole, carbimazole (converted in vivo to methimazole), and propylthiouracil. α-Naphthylthiourea is a commercial rodenticide. Some thioureas are
Thioureas
Chemical compound
test, usually of a piece of paper soaked in PTC (or the less toxic propylthiouracil (PROP)), students are divided into taster and non-taster groups. By
Phenylthiocarbamide
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Eprotirome
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Liothyronine
Physiological capacity
cannot be said about taste. For example, there is a molecule called propylthiouracil (PROP) that some humans experience as bitter, some as almost tasteless
Sense
Ion, and compounds containing the ion
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Perchlorate
Isotope of iodine
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Iodine-131
Medical condition
unclear and possibly harmful. Evidence is unclear for pentoxifylline. Propylthiouracil may result in harm. Evidence does not support supplemental nutrition
Alcoholic_liver_disease
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Liotrix
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thiocyanate
Effect of iodine on the thyroid
was used to treat hyperthyroidism before antithyroid drugs such as propylthiouracil and methimazole were developed. Hyperthyroid subjects given iodide
Wolff–Chaikoff_effect
is able to taste phenylthiocarbamide (PTC) and its derivative 6-n-propylthiouracil (PROP). PTC tastes bitter to many people (tasters) but is tasteless
Taster_(genetics)
Medical term for seeing everything tinted in blue
animal models induced by sildenafil and related drugs. Case Study of Propylthiouracil-Induced Cyanopsia (2023): Published in the Journal of Clinical Endocrinology
Cyanopsia
Sense of chemicals on the tongue
Researchers use two synthetic substances, phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) to study the genetics of bitter perception. These two substances
Taste
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thyromimetic
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Sobetirome
Chemical compound or ion
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Pertechnetate
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Ipodate_sodium
Classification of agents that are possibly carcinogenic to humans
Progestins Progestogen-only contraceptives β-Propiolactone Propylene oxide Propylthiouracil Pulegone Pyridine Quinoline Radiofrequency electromagnetic fields Refractory
IARC_group_2B
Eating behavior in humans
The ability to taste certain bitter thiourea compounds, such as 6-n-propylthiouracil (PROP) and phenylthiocarbamide (PTC), is genetically determined. PROP
Selective_eating
Mammalian protein found in Homo sapiens
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thyroxine-binding_globulin
Chemical compound
an antithyroid preparation. It is a thioamide, closely related to propylthiouracil. Benzylthiouracil has been associated with severe adverse effects,
Benzylthiouracil
Chemical element with atomic number 34 (Se)
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Selenium
Hormones produced by the thyroid gland
at this point. Compounds such as goitrin, carbimazole, methimazole, propylthiouracil can reduce thyroid hormone production by interfering with iodine oxidation
Thyroid_hormones
Amino acid
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Tyrosine
Topics referred to by the same term
(transporter), an osmosensory transporter Prop-, a prefix in chemistry Propylthiouracil (PROP), a thioamide drug Prop (rugby league), a rugby league position
Prop_(disambiguation)
American physician-scientist
problem of hepatotoxicity in children of the anti-thyroid medication propylthiouracil. This finding was the MedScape #1 Endocrine News Story and Alert of
Scott_Rivkees
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
2-Thiouracil
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Triiodothyronine
Rate of energy expenditure by an endotherm at rest
antithyroid agents (drugs used to treat hyperthyroidism) such as propylthiouracil and methimazole bring the metabolic rate down to normal, restoring
Basal_metabolic_rate
Taste of a food that remains after being eaten
or "nontasters" - based on their sensitivity to the bitterness of propylthiouracil and the expression of fungiform papillae on their tongues - has suggested
Aftertaste
Sore on the mucous membrane of the oral cavity
anti-inflammatory drugs, nicorandil (may be prescribed for angina) and propylthiouracil (e.g. used for hyperthyroidism). Some recreational drugs can cause
Mouth_ulcer
Protein produced and used by the thyroid
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thyroglobulin
Topics referred to by the same term
organosulfur thiourea Power transfer unit, for aircraft hydraulic systems Propylthiouracil, a hyperthyroidism drug Puducherry Technological University, Pondicherry
PTU
Autoimmune disease
transthyretin. Altering the extra-thyroidal metabolism of thyroid hormone. Propylthiouracil, glucocorticoids, propranolol, iodinated contrast agents, amiodarone
Hashimoto's_thyroiditis
Organosulfur compound (S=C(NH2)2)
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thiourea
Medical condition
patients associated with other medications, including minocycline, propylthiouracil, and statins. These signs and symptoms are not side effects of the
Drug-induced lupus erythematosus
Drug-induced_lupus_erythematosus
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Sodium_pertechnetate
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Organic_thiocyanates
Enlarged thyroid gland, causing symptoms of hyperthyroidism
multinodular goiter can be treated with antithyroid medications such as propylthiouracil or methimazole, radioactive iodine, or with surgery. Another treatment
Toxic_multinodular_goitre
Potential health issue in pregnancy
defects in the fetus, but propylthiouracil long-term can cause liver side effects in the adult. Carbimazole and propylthiouracil are both secreted in breast
Thyroid_disease_in_pregnancy
propyl docetrizoate (INN) propylhexedrine (INN) propyliodone (INN) propylthiouracil (INN) propyperone (INN) propyphenazone (INN) propyromazine bromide
List_of_drugs:_Pro–Prz
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Potassium_perchlorate
Muscular degeneration due to overproduction of thyroxine by the thyroid
not reduce the damage done by excess thyroxine. Medications such as propylthiouracil and methimazole are administered to block the release of thyroxine
Thyrotoxic_myopathy
Mexican physician, molecular biochemistry
hypothyroidism without the need to use any drugs (e.g., methimazole or propylthiouracil). This animal model has proven to be an extremely valuable tool for
Nancy_Carrasco
Abnormally low concentration of neutrophils (a type of white blood cell) in the blood
Chemotherapy Cytomegalovirus Influenza Human Immunodeficiency Virus Propylthiouracil Levamisole Penicillamine Trimethoprim/sulfamethoxazole Clozapine Valproate
Neutropenia
Type of cellular receptor that facilitates taste
assembly TAS2R37 12 not annotated in human genome assembly TAS2R38 7q34 Propylthiouracil, Phenylthiocarbamide, N-Acyl homoserine lactone TAS2R39 7q34 Denatonium
Taste_receptor
Collective term for blood tests used to check the function of the thyroid
current medical status (such as pregnancy), certain medications like propylthiouracil, temporal effects including circadian rhythm and hysteresis, and other
Thyroid_function_tests
Medical condition
caused by Graves' disease may be treated with the thioamide drugs propylthiouracil, carbimazole or methimazole, or rarely with Lugol's solution. Additionally
Thyroid_disease
Surgical procedure involving partial or complete removal of the thyroid
achieved with the use of antithyroid medications like methimazole or propylthiouracil. Meanwhile, symptoms of hyperthyroidism, such as tachycardia can be
Thyroidectomy
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Tiratricol
Class of enzymes
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Iodothyronine_deiodinase
American geneticist
correlated with a person's ability to taste the bitterness of PROP (propylthiouracil). This finding ultimately led to the discovery by Adler and co-workers
Danielle_Reed
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Genistein
posttraumatic stress disorder) PTT partial thromboplastin time PTU propylthiouracil PTx pneumothorax PU palindromic unit PUBS percutaneous umbilical blood
List of medical abbreviations: P
List_of_medical_abbreviations:_P
Specimens from Two Patients with Graves' Disease Pretreated with Either Propylthiouracil or Stable Iodine: Analysis Using X-Ray Fluorescence and Time-of-Flight
Plummer_effect
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Omzotirome
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
TERN-501
Endocrine disorder in cats
anti-thyroid drugs, known as thioureylenes, are methimazole, carbimazole, and propylthiouracil. Carbimazole is converted to methimazole by the body. These drugs concentrate
Feline_hyperthyroidism
Topics referred to by the same term
PROP can stand for: 6-N-Propylthiouracil (or PROP), a thionamide either tasting very bitter or tasteless depending on genetic makeup PROP (category theory)
PROP
Hungarian researcher (1915–1997)
discovering the association between the ability to taste PROP (6-n-propylthiouracil) with food preferences and body weight, and its relationship to alcohol
Roland_L._Fischer
of pre-eclampsia, low birth weight, miscarriage and preterm birth. Propylthiouracil is the preferred treatment of hyperthyroidism (both overt and subclinical)
Signs and symptoms of Graves' disease
Signs_and_symptoms_of_Graves'_disease
Chemical compound
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Dextrothyroxine
Chemicals regulated in the United States
Propylene glycol mono-t-butyl ether 57018-52-7 Propylene oxide 75-56-9 Propylthiouracil 51-52-5 Pulegone 89-82-7 Pymetrozine 123312-89-0 Pyridine 110-86-1
California Proposition 65 list of chemicals
California_Proposition_65_list_of_chemicals
resistance in Staphylococcus bacteria. The first antithyroid drug, propylthiouracil, is introduced in the United States. The first use of defibrillation
1947_in_science
Serum protein related to amyloid diseases
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Transthyretin
Pharmaceutical drug classification
Levothyroxine sodium and iodine compounds H03BA01 Methylthiouracil H03BA02 Propylthiouracil H03BA03 Benzylthiouracil H03BB01 Carbimazole H03BB02 Thiamazole H03BB52
ATC_code_H03
Mammalian protein found in Homo sapiens
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Sodium/iodide_cotransporter
Nuclear protein
Benzylthiouracil Carbimazole Genistein Methimazole Methylthiouracil Propylthiouracil 2-Thiouracil Thiourea DIOTooltip Iodothyronine deiodinase Inhibitors:
Thyroid_hormone_receptor
Toxicity as observed in the development of an organism
"Teratogen update: antithyroid drugs—methimazole, carbimazole, and propylthiouracil". Teratology. 65 (1): 38–44. doi:10.1002/tera.1096. ISSN 0040-3709
Developmental_toxicity
Medical condition
minocycline (12 cases), ethosuximide combined with a hydantoin (3 cases), propylthiouracil combined with sulphasalazine (3 cases), carbamazepine (3 cases), cysteamine
Childhood-onset systemic lupus erythematosus
Childhood-onset_systemic_lupus_erythematosus
G protein
PDE activation: Other bitter compounds, such as thioacetamide and propylthiouracil, have been shown[by whom?] to have stimulatory effects on PDEs. This
Gustducin
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PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
PROPYLTHIOURACIL
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