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SELADELPAR

  • Seladelpar

    • Chemical compound

    Seladelpar, sold under the brand name Livdelzi, is a medication used for the treatment of primary biliary cholangitis. It is used as the lysine dihydrate

    Seladelpar

    Seladelpar

    Seladelpar

  • Primary biliary cholangitis

    • Autoimmune disease of the liver

    options include obeticholic acid, the PPAR agonists elafibranor and seladelpar, and the off-label use of fibrates. Obeticholic acid (OCA) is FDA-approved

    Primary biliary cholangitis

    Primary biliary cholangitis

    Primary_biliary_cholangitis

  • Peroxisome proliferator-activated receptor delta

    • Nuclear receptor protein found in humans

    nonetheless continued in other indications: the selective PPAR-delta agonist seladelpar received accelerated approval from the US Food and Drug Administration

    Peroxisome proliferator-activated receptor delta

    Peroxisome proliferator-activated receptor delta

    Peroxisome_proliferator-activated_receptor_delta

  • Ibuprofen

    • Nonsteroidal anti-inflammatory drug

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Ibuprofen

    Ibuprofen

    Ibuprofen

  • Fenofibrate

    • Drug of the fibrate class, mainly used to reduce cholesterol levels

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Fenofibrate

    Fenofibrate

    Fenofibrate

  • Telmisartan

    • Blood pressure medication

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Telmisartan

    Telmisartan

    Telmisartan

  • Elafibranor

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Elafibranor

    Elafibranor

    Elafibranor

  • List of drugs granted breakthrough therapy designation

    • 2A gene (KMT2A) translocation in people aged one year of age and older Seladelpar Treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic

    List of drugs granted breakthrough therapy designation

    List_of_drugs_granted_breakthrough_therapy_designation

  • Clofibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Clofibrate

    Clofibrate

    Clofibrate

  • PPAR agonist

    • Drug used for the treatment of symptoms of metabolic syndrome

    changes the body's fuel preference from glucose to lipids. In August 2024, seladelpar became the first PPARδ agonist to be approved for clinical use. A fourth

    PPAR agonist

    PPAR agonist

    PPAR_agonist

  • GW501516

    • Abandoned metabolic and cardiovascular drug

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    GW501516

    GW501516

    GW501516

  • Tianeptine

    • Atypical antidepressant

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Tianeptine

    Tianeptine

    Tianeptine

  • Arachidonic acid

    • 20-Carbon polyunsaturated fatty acid

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Arachidonic acid

    Arachidonic acid

    Arachidonic_acid

  • Berberine

    • Quaternary ammonium cation

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Berberine

    Berberine

    Berberine

  • Pioglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Pioglitazone

    Pioglitazone

    Pioglitazone

  • Cannabigerol

    • Minor cannabinoid

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Cannabigerol

    Cannabigerol

    Cannabigerol

  • Clinofibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Clinofibrate

    Clinofibrate

    Clinofibrate

  • Sodelglitazar

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Sodelglitazar

    Sodelglitazar

    Sodelglitazar

  • Perfluorooctanoic acid

    • Perfluorinated carboxylic acid

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Perfluorooctanoic acid

    Perfluorooctanoic acid

    Perfluorooctanoic_acid

  • Palmitoylethanolamide

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Palmitoylethanolamide

    Palmitoylethanolamide

  • Gemfibrozil

    • Medication

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Gemfibrozil

    Gemfibrozil

    Gemfibrozil

  • Saroglitazar

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Saroglitazar

    Saroglitazar

    Saroglitazar

  • GW0742

    • PPAR β/δ receptor Agonist compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    GW0742

    GW0742

    GW0742

  • Troglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Troglitazone

    Troglitazone

    Troglitazone

  • Estianeptine

    • Pharmaceutical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Estianeptine

    Estianeptine

    Estianeptine

  • Peroxisome proliferator-activated receptor alpha

    • Nuclear receptor protein found in humans

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Peroxisome proliferator-activated receptor alpha

    Peroxisome proliferator-activated receptor alpha

    Peroxisome_proliferator-activated_receptor_alpha

  • Bisphenol A diglycidyl ether

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Bisphenol A diglycidyl ether

    Bisphenol A diglycidyl ether

    Bisphenol_A_diglycidyl_ether

  • Peroxisome proliferator-activated receptor

    • Group of nuclear receptor proteins

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Peroxisome proliferator-activated receptor

    Peroxisome proliferator-activated receptor

    Peroxisome_proliferator-activated_receptor

  • Peroxisome proliferator-activated receptor gamma

    • Nuclear receptor protein found in humans

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Peroxisome proliferator-activated receptor gamma

    Peroxisome proliferator-activated receptor gamma

    Peroxisome_proliferator-activated_receptor_gamma

  • Thiazolidinedione

    • Class of chemical compounds

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Thiazolidinedione

    Thiazolidinedione

    Thiazolidinedione

  • Etomoxir

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Etomoxir

    Etomoxir

  • Fibrate

    • Class of chemical compounds

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Fibrate

    Fibrate

    Fibrate

  • Bocidelpar

    • Pharmaceutical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Bocidelpar

    Bocidelpar

    Bocidelpar

  • List of drugs: Se–Sh

    • Sedapap sedecamycin (INN) Seffin seganserin (INN) seglitide (INN) Sehippy seladelpar (INN) selamectin Selarsdi Selax Seldane Selecor Select 1/35 Selectol selegiline

    List of drugs: Se–Sh

    List_of_drugs:_Se–Sh

  • Tetradecylthioacetic acid

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Tetradecylthioacetic acid

    Tetradecylthioacetic_acid

  • Genistein

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Genistein

    Genistein

    Genistein

  • Perfluorononanoic acid

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Perfluorononanoic acid

    Perfluorononanoic_acid

  • MK-886

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    MK-886

    MK-886

    MK-886

  • Bezafibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Bezafibrate

    Bezafibrate

    Bezafibrate

  • ATC code A05

    • Pharmaceutical drug classification

    A05AX04 Maralixibat chloride A05AX05 Odevixibat A05AX06 Elafibranor A05AX07 Seladelpar A05AX08 Linerixibat QA05AX90 Menbutone A05BA01 Arginine glutamate A05BA03

    ATC code A05

    ATC_code_A05

  • Daidzein

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Daidzein

    Daidzein

    Daidzein

  • Oleoylethanolamide

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Oleoylethanolamide

    Oleoylethanolamide

    Oleoylethanolamide

  • Ronifibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Ronifibrate

    Ronifibrate

  • Rosiglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Rosiglitazone

    Rosiglitazone

    Rosiglitazone

  • Pemafibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Pemafibrate

    Pemafibrate

    Pemafibrate

  • Ciprofibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Ciprofibrate

    Ciprofibrate

    Ciprofibrate

  • Dronabinol/palmidrol

    • Pharmaceutical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Dronabinol/palmidrol

    Dronabinol/palmidrol

    Dronabinol/palmidrol

  • Clofibride

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Clofibride

    Clofibride

    Clofibride

  • Fenofibrate/simvastatin

    • Combination drug

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Fenofibrate/simvastatin

    Fenofibrate/simvastatin

  • Leukotriene B4

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Leukotriene B4

    Leukotriene_B4

  • Selective PPAR modulator

    • Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Selective PPAR modulator

    Selective_PPAR_modulator

  • Ciglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Ciglitazone

    Ciglitazone

    Ciglitazone

  • 15-Hydroxyeicosatetraenoic acid

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    15-Hydroxyeicosatetraenoic acid

    15-Hydroxyeicosatetraenoic acid

    15-Hydroxyeicosatetraenoic_acid

  • Etofibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Etofibrate

    Etofibrate

    Etofibrate

  • Cyclopentenone prostaglandins

    • Prostaglandin subset

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Cyclopentenone prostaglandins

    Cyclopentenone_prostaglandins

  • Lobeglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Lobeglitazone

    Lobeglitazone

  • Simfibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Simfibrate

    Simfibrate

  • Farglitazar

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Farglitazar

    Farglitazar

    Farglitazar

  • EPI-001

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    EPI-001

    EPI-001

  • Aleglitazar

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Aleglitazar

    Aleglitazar

    Aleglitazar

  • Muraglitazar

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Muraglitazar

    Muraglitazar

    Muraglitazar

  • Netoglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Netoglitazone

    Netoglitazone

    Netoglitazone

  • Tesaglitazar

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Tesaglitazar

    Tesaglitazar

    Tesaglitazar

  • Rivoglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Rivoglitazone

    Rivoglitazone

    Rivoglitazone

  • Etalocib

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Etalocib

    Etalocib

    Etalocib

  • Aluminium clofibrate

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Aluminium clofibrate

    Aluminium_clofibrate

  • EHP-102

    • Pharmaceutical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    EHP-102

    EHP-102

    EHP-102

  • Darglitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Darglitazone

    Darglitazone

    Darglitazone

  • Englitazone

    • Chemical compound

    Fonadelpar Genistein GW-0742 GW-501516 L-165,041 Lanifibranor LG-101506 Seladelpar Sodelglitazar Tetradecylthioacetic acid Tianeptine Estianeptine Antagonists:

    Englitazone

    Englitazone

    Englitazone

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