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Malformation of the central digit(s) of the hand or foot
causes of cleft hand related to syndromes have more clarity. The identified mutation for SHSF syndrome (split-hand/split-foot syndrome) a duplication on
Ectrodactyly
Medical condition
In medicine, split hand syndrome is a neurological syndrome in which the hand muscles on the side of the thumb (lateral, thenar eminence) appear wasted
Split_hand_syndrome
Medical condition
Split hand split foot-nystagmus syndrome, also known as Karsch–Neugebauer syndrome, is a rare genetic disorder which is characterized by the absence of
Split hand split foot-nystagmus syndrome
Split_hand_split_foot-nystagmus_syndrome
Neuropsychiatric disorder
Alien hand syndrome (AHS) or alien limb syndrome is a category of conditions in which a person experiences their limbs acting seemingly on their own, without
Alien_hand_syndrome
Syndromes
deletion syndrome 22q11.2 duplication syndrome 22q13 deletion syndrome 2p15-16.1 microdeletion syndrome 2q37 deletion syndrome 3-M syndrome 3C syndrome 3q29
List_of_syndromes
Medical condition
dysplasia–cleft syndrome, or EEC, and also referred to as EEC syndrome and split hand–split foot–ectodermal dysplasia–cleft syndrome is a rare form of
Ectrodactyly–ectodermal dysplasia–cleft syndrome
Ectrodactyly–ectodermal_dysplasia–cleft_syndrome
Hypothetical concept in neuroscience
circulating in the neuroscience community after some split-brain patients exhibited alien hand syndrome (AHS), which led some scientists to believe that there
Dual_consciousness
Condition of the human brain
Split-brain or callosal syndrome is a type of disconnection syndrome when the corpus callosum connecting the two hemispheres of the brain is severed to
Split-brain
Medical condition
syndrome is an extremely rare multiple congenital anomalies syndrome characterized by skeletal and renal abnormalities. These anomalies include split
Acrorenal_mandibular_syndrome
Medical condition
Den Berghe Dequeker syndrome, also known as ulnar hypoplasia-split foot syndrome, is a very rare congenital limb malformation syndrome which is characterized
Van Den Berghe Dequeker syndrome
Van_Den_Berghe_Dequeker_syndrome
Malformation of the limbs
syndrome Split-hand split-foot malformation (SHFM) TAR syndrome (thrombocytopenia with absent radius) Tetra-amelia syndrome Ulbright–Hodes syndrome VACTERL
Congenital_limb_deformities
Mental illness with multiple personality states
remembering memories, and is not a distinct process. However, false memory syndrome per se is not regarded by mental health experts as a valid diagnosis, and
Dissociative identity disorder
Dissociative_identity_disorder
Abnormally short fingers or toes
association between congenital heart disease and Carpenter syndrome and the link between Carpenter syndrome and brachydactyly. Nomograms for normal values of finger
Brachydactyly
Collection of neurological symptoms
interconnections between the two regions. Callosal syndrome, or split-brain, is an example of a disconnection syndrome from damage to the corpus callosum between
Disconnection_syndrome
Congenital genetic disorder which causes oligodactyly and micrognathia
(2010-02-01). "Distal limb deficiencies, micrognathia syndrome, and syndromic forms of split hand foot malformation (SHFM) are caused by chromosome 10q
Buttien-Fryns_syndrome
Split hand split foot malformation autosomal reces Split hand split foot mandibular hypoplasia Split hand split foot-nystagmus syndrome Split hand split foot
List_of_diseases_(S)
Human anatomical variation
Toshihisa; Nakamura, Toshitaka (1 January 2012). "Linburg-comstock syndrome: a case report". Hand Surgery. 17 (2): 217–220. doi:10.1142/S0218810412720197. ISSN 0218-8104
Linburg–Comstock_variation
Genetic disorder which disrupts normal functioning of the olfactory and pituitary glands
Kallmann syndrome (KS) is a genetic disorder that prevents a person from starting or fully completing puberty. Kallmann syndrome is one of a group of
Kallmann_syndrome
Genetic disorder characterized by deformity of the skull, face, and/or limbs
Nager acrofacial dysostosis, also known as Nager syndrome, is a genetic disorder which displays several or all of the following characteristics: underdevelopment
Nager_acrofacial_dysostosis
Medical condition
the palm. Other abnormalities in people with Aarskog–Scott syndrome include heart defects and a split in the upper lip (cleft lip) with or without an opening
Aarskog–Scott_syndrome
Physical anomaly involving extra fingers or toes
type of polydactyly can be associated with syndactyly, cleft hand, and several other syndromes. Polysyndactyly presents various degrees of syndactyly affecting
Polydactyly
Developmental anomaly of fewer fingers and toes
one or more central digits of the hand or foot and is also known as split hand/split foot malformation (SHFM). The hands and feet of people with ectrodactyly
Oligodactyly
Premature fusion of bones in the skull
Pfeiffer syndrome: abnormalities of the skull, hands, and feet; wide-set, bulging eyes, an underdeveloped upper jaw, beaked nose. Saethre–Chotzen syndrome: short
Craniosynostosis
Surgical procedure for epilepsy
resultant split-brain prevents some patients from following verbal commands that require the use of their non-dominant hand. Disconnection syndrome is another
Corpus_callosotomy
Computer keyboard designed with ergonomic considerations
the elbows are not too close together when typing. On the other hand, adjustable split keyboards sometimes intimidate potential users, who may fear they
Ergonomic_keyboard
neurological manifestations Akinetopsia Alexander Disease Alien hand syndrome Allan–Herndon–Dudley syndrome Alternating hemiplegia of childhood Alzheimer's disease
List of neurological conditions and disorders
List_of_neurological_conditions_and_disorders
Medical condition
tibia aplasia/hypoplasia also known as cleft hand absent tibia is a very rare limb malformation syndrome which is characterized by ectrodactyly, and aplasia/hypoplasia
Ectrodactyly with tibia aplasia/hypoplasia
Ectrodactyly_with_tibia_aplasia/hypoplasia
Medical condition
Cracked tooth syndrome (CTS) is where a tooth has incompletely cracked but no part of the tooth has yet broken off. Sometimes it is described as a greenstick
Cracked_tooth_syndrome
Developmental disorder involving the eye
Syndromic microphthalmia is a class of rare congenital anomalies characterized by microphthalmia along with other non-ocular malformations. Syndromic
Syndromic_microphthalmia
RV, Turner S, Ledbetter DH, Martin CL (1993). "17q12 Recurrent Deletion Syndrome". In Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJ, Stephens K, Amemiya
List_of_genetic_disorders
ISBN 978-0-321-80311-5. Sowińska-Seidler A, Socha M, Jamsheer A (February 2014). "Split-hand/foot malformation - molecular cause and implications in genetic counseling"
Mendelian_traits_in_humans
Genetic disease resulting in abnormal formation or function of cilia
lead to a broad spectrum of clinical features. Syndromic ciliopathies, such as Bardet-Biedl syndrome (BBS), typically involve multiple organ systems
Ciliopathy
Disputed medical condition
Shaken baby syndrome (SBS), also known as abusive head trauma (AHT), is a controversial medical condition in children younger than five years old, hypothesized
Shaken_baby_syndrome
Medical condition
seizures or hormone abnormalities. Other features of Pallister–Hall syndrome include a split opening of the airway called bifid epiglottis, laryngeal cleft
Pallister–Hall_syndrome
Dutch wheelchair tennis player
Doubles rankings of #1. Schröder has split hand/split foot syndrome (SHFM), a rare genetic disorder that caused his hands and feet to develop abnormally. He
Sam_Schröder
Ectrodactyly–ectodermal dysplasia–cleft syndrome (EEC syndrome, split hand–split foot–ectodermal dysplasia–cleft syndrome) Epidermolysis bullosa herpetiformis
List_of_skin_conditions
Human chest muscle that protracts the shoulder
It may be split into several parts. Absence of this muscle is rare but happens with certain uncommon diseases, such as the Poland syndrome. Pectoralis
Pectoralis_minor
Medical condition
the fibula (calf bone, long bone lateral to the tibia), ectrodactyly (split hand/foot malformation), and/or brachydactyly (shortened digits) or syndactyly
Fibular aplasia-ectrodactyly syndrome
Fibular_aplasia-ectrodactyly_syndrome
Protein-coding gene in the species Homo sapiens
rearrangements involving the SHFM3 locus at chromosome 10q24 in syndromic and non-syndromic split-hand/foot malformation". Am. J. Med. Genet. A. 140 (13): 1375–83
FBXW4
Occurrence of hand dominance among twins
prenatal complications. For example, the pathological left-handedness syndrome means that an injury occurring during early development can affect lateralization
Twins_and_handedness
Cooling of air in an enclosed space
kW very large: >14 kW Ductless systems (often mini-split, though there are now ducted mini-split) typically supply conditioned and heated air to a single
Air_conditioning
Anthology television series
(Jessica Lange) and her daughter Adelaide (Jamie Brewer), who has Down syndrome. The Harmons' lives are troubled by the meddling Langdons, the incompetent
American_Horror_Story
Performance art using skills of extreme physical flexibility
when the leg is raised toward the back and may be held with one hand while standing. Split (also called: the splits) - Any pose in which the legs are extended
Contortion
1992). "[The heart-hand syndrome. A new variant of disorders of heart conduction and syndactylia including osseous changes in hands and feet]". Kinderarztliche
CACNA1C-Related_Disorders
Condition present at birth regardless of cause
as limb anomalies, syndromes involving multiple systems, and Down syndrome. Recent studies have concluded that 5–9% of Down syndrome cases are due to paternal
Birth_defect
Enlargement of the heart muscle
Yamaguchi was the first to characterize the syndrome and its ventriculargrophic feature in 1979. Yamaguchi syndrome is an infrequent variant of hypertrophic
Hypertrophic_cardiomyopathy
Intimate acts that create sexual arousal
at each other while in a cross-legged position and touching the other's hand palms is a usual foreplay tactic used by tantra practitioners. Tantric foreplay
Foreplay
Infectious disease
bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems
Influenza
Viral pulmonary disease of humans
Hantavirus pulmonary syndrome (HPS), also called hantavirus cardiopulmonary syndrome (HCPS), is a severe respiratory disease caused by hantavirus infection
Hantavirus_pulmonary_syndrome
Inflammation of the lips
orofacial granulomatosis. A related condition is Melkersson–Rosenthal syndrome, a triad of facial palsy, chronic lip edema, and fissured tongue. "Miescher's
Cheilitis
Cheilitis characterized by inflammation of one or both of the corners of the mouth
Melkersson–Rosenthal syndrome, or sideropenic dysphagia (also called Plummer–Vinson syndrome or Paterson–Brown–Kelly syndrome). Several drugs may cause
Angular_cheilitis
Medical condition of the brain
with Richardson syndrome. Management is only supportive because there is currently no known cure for PSP. PSP cases are often split into two subgroups
Progressive supranuclear palsy
Progressive_supranuclear_palsy
Austrian physician (1906–1980)
atypical neurology, specifically in children, and is the namesake of Asperger syndrome. He wrote more than 300 publications on psychological disorders that posthumously
Hans_Asperger
American psychologist and cognitive neuroscientist (born 1939)
ISSN 0278-2626. PMID 14607141. Pirak, Pierangelo (2019-03-06). The Father of Split Brain Syndrome. Retrieved 2025-11-07 – via Vimeo. Turk, David J.; Heatherton, Todd
Michael_Gazzaniga
Arrangement of digits on hands and feet
digits. When all the digits on a hand or foot are absent, it is referred to as adactyly. Ectrodactyly, also known as split-hand malformation, is the congenital
Dactyly
Crevice in the brain separating the frontal and parietal lobes
many others. Previous studies have also shown that the location where the split in the central sulcus occurs is at the division point between the wrist
Central_sulcus
American football player (born 2001)
North Carolina, particularly because his older brother, Miles, has Down syndrome, which Monk cites as formative in developing compassion for others in himself
Jacob_Monk
2004 video game
Spencer Fox (Dash), Sarah Vowell (Violet), and Jason Lee (Buddy Pine/Syndrome/Incrediboy) reprise their roles from the film, with the rest of the cast
The_Incredibles_(video_game)
Defect in the structure of the heart that is present at birth
responsible for a variety of syndromes, including Noonan syndrome, LEOPARD syndrome, Costello syndrome and cardiofaciocutaneous syndrome in which there is cardiac
Congenital_heart_defect
Skull malformation such that the forehead is triangular
occur in a syndrome or isolated, all by itself. Trigonocephaly is associated with the following syndromes: Bohring-Opitz syndrome, Muenke syndrome, Jacobsen
Trigonocephaly
2019 American limited series
person's illness. At the time, this condition was classified as Munchausen syndrome by proxy, by which it is still commonly known. The narrative eventually
The_Act_(TV_series)
Mental disorder with psychotic symptoms
seishin-bunretsu-byō (精神分裂病; lit. 'mind-split disease') to tōgō-shitchō-shō (統合失調症; lit. 'integration–dysregulation syndrome') to reduce stigma and confusion
Schizophrenia
2025 Japanese television season
is "Rocket" performed by Burnout Syndromes. For the series finale, "Good Morning World", performed by Burnout Syndromes, was used for its closing credits
Dr._Stone_season_4
come into the world with innate physical or intellectual hand[i]caps. The term Kanner's syndrome was later coined to describe the children's condition,
History_of_autism
1981 compilation album by Various artists
Seattle Syndrome Volume One is a compilation of Seattle-based bands and artists released on vinyl and cassette in late 1981 on Engram Records. Produced
Seattle_Syndrome_Volume_One
1987 American film
on Blu-ray in December 2015, and is available via Amazon Prime. Vinegar Syndrome released Slaughterhouse on Blu-ray in 2017, from a 2K master direct, from
Slaughterhouse_(film)
State of having one's appearance injured or changed
Joker from various DC Comics and the mysterious figure with a "red right hand" from the song of the same name by the band Nick Cave and the Bad Seeds.
Disfigurement
agro-pastoralists and their spread to all corners of the planet. Domestication syndrome is a term often used to describe the suite of phenotypic traits arising
Domestication_of_vertebrates
immunodeficiency, despite the condition's popular nickname ("bubble boy syndrome") and its portrayal in films. A bone marrow transplant in the earliest
List of common misconceptions about science, technology, and mathematics
List_of_common_misconceptions_about_science,_technology,_and_mathematics
Injuries caused by climbing
One injury that tend to be very common among climbers is Carpal tunnel syndrome. It is found in about 25% of climbers. 604 injured rock climbers were prospectively
Climbing_injuries
American football player (born 2002)
Wisconsin. In his first season, Fourqurean dealt with Thoracic outlet syndrome, limiting his playing time. In 2024, Fourqurean was the team's starting
Nyzier_Fourqurean
Businessman and entrepreneur (born 1971)
that he has Asperger syndrome. He was not diagnosed as a child. When asked about his experience growing up with Asperger's syndrome the following year,
Elon_Musk
Irish actor (born 1976)
Colin Farrell Foundation in dedication to his son James, who has Angelman syndrome. The organization provides support to adults with intellectual disabilities
Colin_Farrell
2023 American science fiction television series
deputy and a former Judicial administrator who is afflicted with the "Syndrome", a medical condition that causes tremors Shane McRae as Deagan Knox (season
Silo_(TV_series)
Lamellar splitting of the distal nail plate
nail syndrome. The most common cause is repeated exposure of the nails to water and drying agents. Other contributing factors include: Frequent hand washing
Onychoschizia
Means by which a person dies by suicide
John E., Frances, Richard J. (1986). "The acquired immune deficiency syndrome (AIDS) and suicidal behavior in alcohol-dependent homosexual men". The
Suicide_methods
British automotive company
Porsche, which left him in a coma and ultimately suffering from locked in syndrome. The team did not race at Zhuhai for the final race of the 1996 season
Lanzante_Limited
Sexual activity involving stimulation of the genitalia by use of the mouth
some way, such as semen in the ejaculate finding its way onto fingers, hands, or other body parts, which then comes in contact with the vaginal area
Oral_sex
American family of entertainers
(1907–1990). She was left with a permanent limp after acquiring polio syndrome in her childhood. She later recovered from her illness after moving with
Jackson_family
American rock band
Retrieved March 20, 2019. "The Quietus | Features | Escape Velocity | Stendhal Syndrome: Idles Interviewed". The Quietus. June 29, 2017. Retrieved March 20, 2019
Protomartyr_(band)
Species of bird
being trapped by a Ministry of Agriculture and Fisheries contractor. A syndrome of uncertain etiology affects rainbow lorikeets every year; in southeast
Rainbow_lorikeet
American actress and author (born 1980)
behavioral aide to the child character Max who is diagnosed with Asperger syndrome. Kelly went on to appear in nine episodes of the show before making her
Minka_Kelly
Japanese manga series
manga was going on hiatus due to him recovering from steroid withdrawal syndrome. An anime television series adaptation was announced on January 27, 2026
Nippon_Sangoku
Psychological or sexual drive or energy
termed post-retinoid sexual dysfunction/post-Accutane syndrome (PRSD/PAS), post-finasteride syndrome (PFS) and post-SSRI sexual dysfunction (PSSD). These
Libido
American football player (born 1997)
loss. He was placed on injured reserve on October 3, due to compartment syndrome in his calf. Pittman was activated on October 31. In Week 9 against the
Michael_Pittman_Jr.
2001 EP by The Locust
Amnesia" – 1:06 "Get Off the Cross, the Wood Is Needed" – 0:42 "Wet Nurse Syndrome Hand-Me-Down Display Case" – 0:34 "This Is Radio Surgery" – 0:41 "Spitting
Flight_of_the_Wounded_Locust
Season of television series
end of the task, the wardens handed out a total of 28 fines, therefore accumulating 28 eyeballs which they opted to split between themselves. Following
Big Brother (British TV series) series 22
Big_Brother_(British_TV_series)_series_22
accident or misadventure. People who may or may not have died by their own hand, whose intent to die is disputed, or who are alleged to have been killed
List of suicides (2000–present)
List_of_suicides_(2000–present)
American actor (1934–2020)
established character actor in the 1970s and 1980s in films such as The China Syndrome (1979), The Thing (1982), Tender Mercies (1983), The Natural (1984), Cocoon
Wilford_Brimley
American mass murderer (1992–2012)
could not touch a doorknob with his bare hand. When he was 13, Lanza was diagnosed with Asperger's syndrome by psychiatrist Paul Fox. Lanza exhibited
Adam_Lanza
List of episodes of the BBC sitcom
2021. Retrieved 19 September 2016. "Only Fools and Horses - Time on Our Hands (1996)". www.bbc.co.uk. Retrieved 9 May 2022. "Only Fools and Horses - If
List of Only Fools and Horses episodes
List_of_Only_Fools_and_Horses_episodes
2025 American medical drama
2025. Pucci, Douglas (October 9, 2025). "Tuesday Ratings: ABC and FS1 Split Prime Time Victory". Programming Insider. Archived from the original on
Doc_(2025_TV_series)
60th United States presidential inauguration
2025). "Trump doesn't place hand on Bible during swearing-in". ABC News. Retrieved January 20, 2025. "Trump did not put his hand on the Bible at inauguration
Second inauguration of Donald Trump
Second_inauguration_of_Donald_Trump
Birth defect of the palate and upper lip
associated with a syndrome (syndromic) or may not be associated with a syndrome (nonsyndromic). Syndromic clefts are part of syndromes that are caused by
Cleft_lip_and_cleft_palate
Long-term inflammatory disease of the airways of the lungs
symptoms, outcomes, and response to treatment, asthma is often considered a syndrome—a collection of signs and symptoms—rather than a single condition. Historically
Asthma
President of the United States (2017–2021; since 2025)
prevailed in 195 cases, the government had prevailed in 109 cases, there were split rulings in 16 cases, 228 cases were pending, and 25 cases were closed. Both
Donald_Trump
Forearm muscle which extends the index finger
radialis. Split tendons of the muscle inserting on both ulnar and the radial side of the common extensor digitorum was also reported. Anomalous hand extensors
Extensor_indicis_muscle
American football player (born 1998)
During his freshman year, Cooper was diagnosed with Wolff–Parkinson–White syndrome, a rare heart condition that often manifests in an abnormally fast heartbeat
Jonathon_Cooper
Alberto Blanco, Joaquib, Abdul, Alex Gutierrez), Gominolas 1988 Alien Syndrome ACE Software Pamela Roberts, Jack Wilkes, Mike Marchant Sega 1988 Garfield:
List_of_ZX_Spectrum_games
American boxer (born 1949)
alive. The Holmes fight is said to have contributed to Ali's Parkinson's syndrome. After eight consecutive knockouts, Holmes was forced to go the distance
Larry_Holmes
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SPLIT HAND-SYNDROME
SPLIT HAND-SYNDROME
SPLIT HAND-SYNDROME
SPLIT HAND-SYNDROME
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SPLIT HAND-SYNDROME
SPLIT HAND-SYNDROME
SPLIT HAND-SYNDROME
SPLIT HAND-SYNDROME
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