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TELITHROMYCIN

Telithromycin

Chemical compound

Telithromycin is the first ketolide antibiotic to enter clinical use and is sold under the brand name of Ketek. It is used to treat community acquired

Telithromycin

Ketolide

was recognized that use of telithromycin can result in hepatitis and liver failure. Scheinfeld, N (July 2004). "Telithromycin: a brief review of a new ketolide

Ketolide

Solithromycin

Chemical compound

the telithromycin side chain acting as an antagonist towards various nicotinic acetylcholine receptors. Solithromycin differs from telithromycin because

Solithromycin

Macrolide

Class of natural products

effective, as they have two ribosomal binding sites. Ketolides include: Telithromycin – the first and only approved ketolide Cethromycin Solithromycin Fluoroketolides

Macrolide

Dapoxetine

Medication used to treat premature ejaculation

those receiving CYP3A4 inhibitors such as ketoconazole, ritonavir, and telithromycin. Dapoxetine also cannot be used in patients with heart failure, permanent

Dapoxetine

Timeline of antibiotics

quinupristin/dalfopristin 2000 – linezolid, the first oxazolidinone 2001 – telithromycin, the first ketolide 2003 – daptomycin 2005 – tigecycline, the first

Timeline of antibiotics

Timeline_of_antibiotics

Myasthenia gravis

Autoimmune disease resulting in skeletal muscle weakness

Antibiotics: In the macrolide family of antibiotics, azithromycin, telithromycin (which is no longer available in the U.S. market), and erythromycin

Myasthenia gravis

Myasthenia_gravis

Atorvastatin

Cholesterol-lowering medication

of atorvastatin with one of CYP3A4 inhibitors such as itraconazole, telithromycin, and voriconazole, may increase serum concentrations of atorvastatin

Atorvastatin

Simvastatin

Lipid-lowering medication

or posaconazole; the antibiotics erythromycin, clarithromycin, or telithromycin; HIV protease inhibitors; the antidepressant nefazodone; the cardiovascular

Simvastatin

Sanofi

French multinational pharmaceutical and healthcare company

Dynabac (Dirithromycin), for acute bacterial exacerbations. Ketek (Telithromycin), for community acquired pneumonia. Priftin (Rifapentine), for tuberculosis

Sanofi

Eravacycline

Chemical compound

Tylvalosin Azalides Azithromycin# Gamithromycin Tulathromycin Ketolides Telithromycin‡ Cethromycin Solithromycin† Lincosamides Clindamycin# Lincomycin Pirlimycin

Eravacycline

Suvorexant

Medication used to treat insomnia

nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use not recommended); the moderate CYP3A4 inhibitors amprenavir

Suvorexant

Bactericide

Agent which kills bacteria

daptomycin, fluoroquinolones, metronidazole, nitrofurantoin, co-trimoxazole, telithromycin. Aminoglycosidic antibiotics are usually considered bactericidal, although

Bactericide

CYP3A4

Enzyme that metabolizes substances by oxidation

itraconazole macrolides (except azithromycin): clarithromycin, erythromycin, telithromycin; dapsone (in leprosy), tricyclic antidepressants: amitriptyline, clomipramine

CYP3A4

Daridorexant

Medication used to treat insomnia

nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, and telithromycin (concomitant use not recommended); the moderate CYP3A4 inhibitors amprenavir

Daridorexant

Dronedarone

Medication

clarithromycin, cyclosporine, itraconazole, ketoconazole, nefazodone, ritonavir, telithromycin, voriconazole) Clinical trials have compared dronedarone to placebo

Dronedarone

List of antibiotics

Clarithromycin Biaxin Erythromycin Erythocin, Erythroped Roxithromycin Telithromycin Ketek Pneumonia Visual disturbance, liver toxicity. Spiramycin Rovamycine

List of antibiotics

List_of_antibiotics

Abiraterone acetate

Chemical compound

itraconazole, clarithromycin, atazanavir, nefazodone, saquinavir, telithromycin, ritonavir, indinavir, nelfinavir, voriconazole) or inducers such as

Abiraterone acetate

Abiraterone_acetate

Aliskiren

Medication

moderate P-glycoprotein inhibitors such as itraconazole, clarithromycin, telithromycin, erythromycin, or amiodarone. Recommendations have been made to stop

Aliskiren

Dihydrostreptomycin

Chemical compound

Tylvalosin Azalides Azithromycin# Gamithromycin Tulathromycin Ketolides Telithromycin‡ Cethromycin Solithromycin† Lincosamides Clindamycin# Lincomycin Pirlimycin

Dihydrostreptomycin

ATC code J01

Pharmaceutical drug classification

J01FA12 Rokitamycin J01FA13 Dirithromycin J01FA14 Flurithromycin J01FA15 Telithromycin J01FA16 Solithromycin J01FA17 Nafithromycin QJ01FA90 Tylosin QJ01FA91

ATC code J01

ATC_code_J01

List of drugs: Te

telinavir (INN) telisotuzumab vedotin (INN) telisotuzumab vedotin-tllv telithromycin (USAN) telmesteine (INN) telmisartan (INN) telotristat (USAN, INN) teloxantrone

List of drugs: Te

List_of_drugs:_Te

Protein synthesis inhibitor

Inhibitors of translation

Chloramphenicol Clindamycin Linezolid (an oxazolidinone) Macrolides Telithromycin Streptogramins Retapamulin Biology portal Protein biosynthesis Bacterial

Protein synthesis inhibitor

Protein_synthesis_inhibitor

List of cytochrome P450 modulators

Saquinavir Seproxetine ((S)-norfluoxetine/ Fluoxetine metabolite) Star fruit Telithromycin Valerian Valproic acid Verapamil Voriconazole Armodafinil Barbiturates

List of cytochrome P450 modulators

List_of_cytochrome_P450_modulators

Ezetimibe/simvastatin

Drug combination used for the treatment of dyslipidemia

amounts of niacin (nicotinic acid), grapefruit juice Erythromycin, telithromycin, clarithromycin Nefazodone The combination of ezetimibe and simvastatin

Ezetimibe/simvastatin

Vorapaxar

Chemical compound

ritonavir, saquinavir, nelfinavir, indinavir, boceprevir, telaprevir, telithromycin, and conivaptan. CYP3A4 inducers, such as carbamazepine, rifampin, St

Vorapaxar