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RNA base pair that does not follow Watson–Crick base pair rules
wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson–Crick base pair rules. The four main wobble base pairs
Wobble_base_pair
Base pairs in molecular genetics
base pairs in RNA include the G:U wobble pair, sheared G:A pair, reverse Hoogsteen A:U pair, and G:A imino pair. Together, these alternative pairings
Non-canonical_base_pairing
Nucleic acid pairing variations
composed of stacked associations of Hoogsteen bonded guanine molecules. Wobble base pair Nucleic acid tertiary structure Polypurine reverse-Hoogsteen hairpins
Hoogsteen_base_pair
Topics referred to by the same term
creating wobble base pairs in Crick's wobble hypothesis Jah Wobble (John Joseph Wardle, born 1958), English musician Speed wobble, a rapid side-to-side
Wobble
Redundancy of codons in the genetic code
of modified bases in the first base of the anticodon of the tRNA, and the base-pair formed is called a wobble base pair. The modified bases include inosine
Codon_degeneracy
Two nucleobases bound by hydrogen bonds
with two hydrogen bonds, does occur fairly often in RNA (see wobble base pair). Paired DNA and RNA molecules are comparatively stable at room temperature
Base_pair
Basepairing interactions within a single nucleic acid polymer or between two polymers
(U). Alternate hydrogen bonding patterns, such as the wobble base pair and Hoogsteen base pair, also occur—particularly in RNA—giving rise to complex
Nucleic acid secondary structure
Nucleic_acid_secondary_structure
Chemical compound
though it is a conventional partner for adenosine since it will also "wobble base pair" with guanosine. Lysidine is denoted as L or k2C (lysine bound to C2
Lysidine_(nucleoside)
Macromolecular machine that synthesizes proteins in cells
Posttranslational modification Protein dynamics Ribosome-associated vesicle Wobble base pair Bashan, Anat; Agmon, Ilana; Zarivach, Raz; Schluenzen, Frank; Harms
Ribosome
Family of large biological molecules
adenine and uracil, while guanine and uracil can pair through a non-canonical G–U wobble base pair. However, other interactions are possible, such as
RNA
Synthetic DNA analog experiment
unnatural nucleobases would perform these pairings, causing bases to be replaced. An analogue of the G·U wobble base pair can be formed between aminoA and 5-methylisocytidine
Artificially Expanded Genetic Information System
Artificially_Expanded_Genetic_Information_System
DNA mutation
transitions are less likely to result in amino acid substitutions (due to wobble base pair), and are therefore more likely to persist as "silent substitutions"
Transversion
Three-dimensional shape of a nucleic acid polymer
Base pair – Two nucleobases bound by hydrogen bonds Wobble base pair – RNA base pair that does not follow Watson–Crick base pair rules Hoogsteen base
Nucleic acid tertiary structure
Nucleic_acid_tertiary_structure
Chemical compound
tRNAs and is essential for proper translation of the genetic code in wobble base pairs. Knowledge of inosine metabolism has led to advances in immunotherapy
Inosine
vision – vitamin - Viroid water cycle – wavelength – welfare biology – Wobble base pair – wood xanthophyll – X chromosome – xenobiology – X-ray diffraction
Index_of_biology_articles
RNA that facilitates the addition of amino acids to a new protein
complementary base pairs to one or more codons for an amino acid. Some anticodons pair with more than one codon due to wobble base pairing. Frequently,
Transfer_RNA
RNA family
orientations, there are many G-U wobble base pairs and their reverse complements A-C pairs, and both strands have too many A-C pairs to confidently establish
DUF2693_RNA_motif
Chemical compound
usually occur on the first base on the anticodon (position 34 or the wobble base position) which base pairs with the third base on the codon and are critical
Agmatidine
American molecular biologist and academic
identification in 1988 of a helical tRNA irregularity set up by a G-U wobble base pair in the alanine system and again in 2002 was confirmed in 2014 by direct
William_H._McClain
Compound analogous to naturally occurring RNA and DNA
among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases
Nucleic_acid_analogue
the first position are capable of pairing with more than one codon due to a phenomenon known as wobble base pairing. antigen Any exogenous agent that
Glossary of cellular and molecular biology (0–L)
Glossary_of_cellular_and_molecular_biology_(0–L)
Form of evolutionary mutation
one tRNA can have a non-standard wobble base in position three of the anti-codon, which recognises more than one base in the codon. In the above phenylalanine
Synonymous_substitution
Type of mutation in a DNA sequence
of their original codon, but UAA suppressors also read UAG due to wobble base pairing. UGA suppressors are very rare. Another hurdle to pass in this technique
Nonsense_mutation
Molecular process
base pairing, therefore rendering that particular dsRNA less able to produce siRNA, which interferes with the RNAi pathway. The wobble base pairing causes
RNA_editing
English rock band
trying to be different". He approached Jah Wobble (né John Wardle) about forming a band together. The pair had been friends since the early 1970s when
Public_Image_Ltd
Application of computational algorithms, methods and programs to phylogenetic analyses
position of a given site within a codon, since it is known that wobble base pairing can allow for higher mutation rates in the third nucleotide of a
Computational_phylogenetics
English physicist and biologist (1916–2004)
descriptions of redirect targets Crick's wobble hypothesis – RNA base pair that does not follow Watson–Crick base pair rules History of RNA biology List of
Francis_Crick
DNA located in cellular organelles called chloroplasts
sense codons by conventional wobble base pairing. This reduced set is sufficient because of an expanded form of wobbling called superwobble, in which
Plastid_DNA
Figure formed by two rays meeting at a common point
Linton, John Alexander (1973), Phase and amplitude variation of Chandler wobble (Thesis), University of British Columbia, doi:10.14288/1.0052929, archived
Angle
Season of television series
Tomatoes reported an approval rating of 89% with an average score of 8.13/10, based on 18 reviews. The website's critics consensus reads, "The third season
Veronica_Mars_season_3
RNA family
had fewer A-C base pairs, which do not contribute to RNA stability. In reverse complement, an A-C pair becomes the stable G-U wobble pair. Weinberg Z,
Anti-hemB_RNA_motif
British animated children's television series
changed when Tronjiworld was struck by a natural disaster, known simply as "Wobble", which caused immense destruction to Tronjiworld by draining away its colour
Tronji
Plug-in vacuum tube holder
(although they will fit into a standard octal socket, they wobble and do not make good contact), the base shell was made of aluminium, and the center hole had
Tube_socket
occurring base in human tRNA or in wobble base pairing, it is mistakenly incorporated into DNA either through the deamination of an adenine base pair, or as
DNA-deoxyinosine_glycosylase
brings Amy a racehorse. Cassandra's initial diagnosis is that the horse has Wobbler disease. Janice feels the need to have the horse euthanized due to the
List_of_Heartland_episodes
Scottish musical group
Skinny. Retrieved 2 January 2020. "Album reviews: The Proclaimers | Jah Wobble | Giant Sand | Israel Nash". The Scotsman. 8 August 2018. Retrieved 2 March
The_Proclaimers
2024 film by Sean Baker
how "an overlong runtime, underwritten characters and some uneasy tonal wobbles dampen the film's punchy humour and propulsive energy". He wrote of one
Anora
Bacterial lawn Bacteriophage Balbiani ring Barr body Basal body Base Base analogue Base pair Base pairs Base sequence Batesian mimicry Bayesian analysis Bead
Index_of_genetics_articles
English bassist (1957–1979)
his bandmate, guitarist Steve Jones; and Vicious nicknamed Wardle "Jah Wobble". When Ritchie turned 16, Anne kicked him out of her home. In a 1988 interview
Sid_Vicious
Nucleotide pattern causing frameshifting
sequences are common in virus polyproteins. The frameshift occurs due to wobble pairing. The Gibbs free energy of secondary structures downstream give a hint
Slippery_sequence
Chemical compound
acid, asparagine and tyrosine. The first anticodon position pairs with the third "wobble" position in codons, and queuosine improves accuracy of translation
Queuosine
Season of television series
Tape Tumble"), nominees must attempt to retrieve video tapes placed on a wobble tower. Players can rearrange the tower as they collect the tapes, but if
Big Brother 28 (American season)
Big_Brother_28_(American_season)
1966 American comedy film by Stanley Donen
used a lot lately, especially in Europe, but the trouble had been too much wobble because the operator has to carry the sheer weight of the camera while he's
Arabesque_(film)
Topics referred to by the same term
of free jazz albums by Don Cherry, released in 1969 and 1970 Mu, by Jah Wobble M.U. – The Best of Jethro Tull, a greatest hits album Mu Vol. I, an EP album
MU
Laser-guided aerial bomb family
canard deflections to make course corrections, resulting in a noticeable wobble. This had relatively little effect on accuracy, but expends energy quickly
Paveway
Hypothetical stage in the early evolutionary history of life on Earth
particularly susceptible to mutations that can replace a GC base pair with a GU (wobble) or AU base pair. RNA is thought to have preceded DNA, because of their
RNA_world
Northernmost point on Earth
century, the mathematician Leonhard Euler predicted that the axis might "wobble" slightly. Around the beginning of the 20th century astronomers noticed
North_Pole
Ukrainian boxer (born 1976)
was following his jabs with his signature straight right. Wach managed to wobble Klitschko in round five but failed to take advantage. Wach also showed a
Wladimir_Klitschko
19th century Irish song
article as being thought to be a modern dance and the title was reportedly based on a particular road in Clonmel. No lyrics were given, but the song was
Rocky_Road_to_Dublin
2022 Marvel Studios film
Retrieved May 15, 2022. D'Alessandro, Anthony (May 15, 2022). "Wizard Wobble A Wake-Up Call For Marvel As 'Doctor Strange 2' Falls 67% In Weekend 2;
Doctor Strange in the Multiverse of Madness
Doctor_Strange_in_the_Multiverse_of_Madness
Norwegian chess grandmaster (born 1990)
Generation Cup". en.chessbase.com. 2 October 2024. "Magnus Carlsen recovers from wobble to complete double in Kolkata; Arjun Erigaisi slips up". The Indian Express
Magnus_Carlsen
Musical
it out, and they go off in search of The Werkling. Badjelly's sisters, Wobble and Ice Cream arrive back to the Land of the Bumbly Boo after a day of pretending
Badjelly's_Bad_Christmas
Device for various rides and attractions
mounted on the floor. The bridges or walkways can be designed to tilt, wobble or vibrate as visitors proceed along the path, providing unstable footing
Spinning_tunnel
Portion of gene's sequence which codes for protein
mismatch repair following replication, and the 'Wobble Hypothesis' which describes the degeneracy of the third base within an mRNA codon. While it is well known
Coding_region
High-altitude, supersonic reconnaissance aircraft
at an altitude of about twenty feet (six meters), because of serious wobbling caused by improper hookup of some navigational controls. Instead of circling
Lockheed_A-12
Methods to produce stereoscopic images
to adjust the stereo base (parallax) in proportion to the zoom (perspective). If a picture is taken with a stereo camera (or pair of cameras) and a 4X
Stereo_photography_techniques
Species of owl
half-spread wings, and may wobble and twist their heads from side to side. Courting pairs often engage in duets. Copulation between pairs usually occurs in late
Barred_owl
2026 studio album by Gorillaz
also introduced gate weave – which gives the video the same characteristic wobble of film as it runs through a projector – to reinforce the film texture effect
The_Mountain_(Gorillaz_album)
British composer and producer
Holding Pattern as source material for its production. His 9th studio album, Wobble Factor would be unveiled later in 2008, and solidified Tipper's influence
David_Tipper
Belarusian tennis player (born 1998)
berth". WTA Tennis. 19 August 2023. Retrieved 28 July 2026. "Sabalenka wobbles before seeing off Zanevska at US Open". Reuters. 30 August 2023. Retrieved
Aryna_Sabalenka
Phenomenon during translation of mRNA
PMC 4749135. PMID 26661048. Crick FH (August 1966). "Codon—anticodon pairing: the wobble hypothesis". Journal of Molecular Biology. 19 (2): 548–555. doi:10
Ribosomal_frameshift
English boxer (born 1982)
Bellew, forcing him to move away against the ropes. Another left hand wobbled Bellew before Usyk finished him off with another left which dropped Bellew
Tony_Bellew
German general and politician (1865–1937)
kept up against all agitators, croakers, and weaklings". To bolster the wobbling Austro-Hungarian government, the Germans provided some troops and led a
Erich_Ludendorff
Soviet/Russian air-to-surface missile
spin, making it 'wobble', similar to an improperly thrown (American) football. When the missile has a desirable attitude in its wobbling pattern, the canard
9K121_Vikhr
English drummer
visceral impact, rich texturing and smart distortions adding a destabilising wobble". The album was issued on vinyl, CD and digital. Budgie and Tolhurst toured
Budgie_(musician)
2026 studio album by Raye
found the album to be "a lot" - overstuffed with ideas - and said it "wobbles unsteadily along the line that separates unbridled self-expression from
This_Music_May_Contain_Hope
American actor, director and author (born 1970)
come". Entertainment Weekly commented that although A Lie of the Mind "wobbles a bit in its late stages", Hawke's "hearty" revival managed to "resurrect
Ethan_Hawke
American singer (born 1981)
as a Mariah Carey influence. "Freakshow" The track is built around the 'wobbler' effect of dubstep, and her vocals are pitched down low, making her sound
Britney_Spears
across the screen. "67" and similar searches causes the screen to briefly wobble, akin to the hand gesture associated with the slang term. "afghanistan"
List_of_Google_Easter_eggs
Aromatic compound (C4H4N2)
bonding modes are for classical Watson–Crick base pairing. Other hydrogen bonding modes ("wobble pairings") are available in both DNA and RNA, although
Pyrimidine
RNA family
the same tertiary stacking interactions as well. The formation of a GU wobble pair early in the U2-U6 folding event is also observed in the formation of
U2_spliceosomal_RNA
German football manager (born 1973)
an incredible 12 months and the battle to avoid a Chelsea second-year wobble". The Athletic. Archived from the original on 13 May 2022. Retrieved 13
Thomas_Tuchel
Machine that washes clothes
"洗濯機". "WA16F7L4UWA Wobble Technology 16 kg | WA16F7L4UWACX6 | Samsung Caribbean". Samsung latin_en. Retrieved 2018-02-19. "Wobble Technology". www.samsung
Washing_machine
British professional boxer (1978–2025)
exchanges. In round eight, Hatton absorbed a left hook to the chin that wobbled him. In round ten, Hatton was hurt again by a left hook. Despite that,
Ricky_Hatton
Chemical compound
made by chemical methylation of pseudouridine. While pseudouridine can wobble-pair with bases other than A, work examining COVID-19 modRNA vaccines that
N1-Methylpseudouridine
1971 British film by Mike Hodges
of the film's title theme in 1999. Jah Wobble produced a dub cover version of the theme tune in 2009. Wobble had long been a fan of the bassline of the
Get_Carter
Italian flagship sports car produced from 1987–1996
tubes at chassis base datum level to do all the work, and it shows – you can feel the chassis flexing on the circuit and it wobbles all over the place
Ferrari_F40
British children's comedy TV show
doing some clever talents (eg, balancing something on his nose or playing a pair of spoons), or telling some jokes to them. He also has a running gag, which
Justin's_House
Pakistani former cricketer
his development of his seam movement, saying he watched Asif bowl his "Wobble Seam" method. After impressing in domestic Pakistani cricket, Asif was fast
Mohammad_Asif_(cricketer)
2003 single by O-Zone
sequences. While The Guardian's Alexis Petridis remarked that the track "wobbles unsteadily along the line that separates catchy from infuriating", Lauren
Dragostea_din_tei
2021–22 group of superhero media
Retrieved April 26, 2021. D'Alessandro, Anthony (May 15, 2022). "Wizard Wobble A Wake-Up Call For Marvel As 'Doctor Strange 2' Falls 67% In Weekend 2;
Marvel Cinematic Universe: Phase Four
Marvel_Cinematic_Universe:_Phase_Four
2011 studio album by James Blake
by Feist. The song uses only Blake's singing, piano, percussion, and a wobble bassline. This is followed by "Give Me My Month", a short piano ballad,
James_Blake_(album)
Australian rock band
on 16 June 2008. Retrieved 2 August 2008. Dunn, Emily (18 July 2007). "A Wobble, but the Wiggles Still Rule". The Sydney Morning Herald. Archived from the
AC/DC
2013 animated film by Jimmy Hayward
November 1, 2013. Hiltbrand, David (November 1, 2013). "'Free Birds': A gobble wobble". The Philadelphia Inquirer. Archived from the original on November 6, 2013
Free_Birds
Japanese anime television series
series that aired on Fuji TV from October 14, 1981, to March 19, 1986. Based on the manga series of the same name by Rumiko Takahashi, it was produced
Urusei Yatsura (1981 TV series)
Urusei_Yatsura_(1981_TV_series)
Hawaiian Vacation. Roly-Poly Clown is a toy clown that jingles when it is wobbled. It only appears in the first two films. A hockey puck with yellow gloves
List_of_Toy_Story_characters
German automotive manufacturer
Elvis Presley. A prototypical dashboard figure—later named "Wackel-Elvis" ("Wobble Elvis" or "Wobbly Elvis")—appeared in the commercials to demonstrate the
Audi
American boxer and boxing promoter (born 1977)
advantage of Ortiz not having his hands up and unloaded a left hook which wobbled Ortiz. Ortiz then looked at the referee, and Mayweather connected with
Floyd_Mayweather_Jr.
Working dog breed
Mohammad M.; Yamato, Osamu (2012). "Rapid genotyping assays for the 4–base pair deletion of canine MDR1 / ABCB1 gene and low frequency of the mutant allele
Border_Collie
Continuously variable transmission made by Audi
Presley. A prototypical dashboard figure - later named "Wackel-Elvis" ("Wobble Elvis" or "Wobbly Elvis") - appeared in the commercials to demonstrate the
Multitronic
Natural satellite orbiting Earth
Both the Earth and the Moon actually orbit this center of mass, so Earth wobbles around this point for every orbit the Moon makes. This barycenter is slowly
Moon
RNA sequence directing the translation of UGA codons as selenocysteines
is interrupted by a stem. The eukaryotic SECIS element includes wobble A-G base pairs, which are uncommon in nature, but are critically important for
SECIS_element
Nigerian professor and philosopher (1935-2018)
depicted as ugly dark skinned short men with a tendency to drink and a wobble when he walked, Socrates was said to be poor whereas Orunmila was said to
Sophie_Oluwole
Pokémon species
the English localization. The English name is a combination of buffet and wobble, a reference to its ability to handle taking multiple hits. The name was
Wobbuffet
American animated television series
The Midnight Gospel." In a mixed review, Jesse Schedeen from IGN said "It pairs a laid-back, talk-heavy approach with lavish, surrealist animation. But
The_Midnight_Gospel
Season of television series Australian Survivor
the eleventh to air on Network 10, premiering on 17 August 2025 and is based on the international reality competition franchise Survivor. In this special
Australian Survivor: Australia V The World
Australian_Survivor:_Australia_V_The_World
Gaseous phase of water
sunlight on water vapor. In the tropics, a band of extremely humid air wobbles north and south of the equator as the seasons change. This band of humidity
Water_vapor
President of Russia from 1991 to 1999
neurological disorder that affected his sense of balance, causing him to wobble as if in a drunken state; the goal of the operation was to reduce the pain
Boris_Yeltsin
Large flightless seabird endemic to Antarctica
6 mph). On land, the emperor penguin alternates between walking with a wobbling gait and tobogganing—sliding over the ice on its belly, propelled by its
Emperor_penguin
Fictional character from Dead or Alive
spent significant time adjusting the model, particularly the wobble of her breasts, based on Team Ninja's feedback. In non-Koei Tecmo produced titles,
Ayane_(Dead_or_Alive)
travel, tourism, insurance
WOBBLE BASE-PAIR
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