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Protein-coding gene in humans
YTH domain family, member 1 is a protein that in humans is encoded by the YTHDF1 gene. N6-Methyladenosine GRCh38: Ensembl release 89: ENSG00000149658 – Ensembl
YTHDF1
Modification in mRNA, DNA
named m6A readers. The YT521-B homology (YTH) domain family of proteins (YTHDF1, YTHDF2, YTHDF3 and YTHDC1) have been characterized as direct m6A readers
N6-Methyladenosine
Protein domain
by scanning the mRNA to find the modified bases. The YTH domain proteins YTHDF1, YTHDF2, and YTHDF3 can bind to modified bases and the surrounding bases
YTH_protein_domain
Human chromosome
VAPB: VAMP (vesicle-associated membrane protein)-associated protein B and C YTHDF1: encoding protein YTH domain family, member 1 ZFP64 encoding protein Zinc
Chromosome_20
Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress
YES1 Tyrosine-protein kinase Yes YLPM1 YLPM1 YLP Motif Containing 1 YTHDF1 YTHDF1 YTH domain family protein 1 YTHDF2 YTHDF2 YTH domain family protein
Stress_granule
Chemical compound
Cholangiocarcinogenesis Involves the Hippo Pathway Effector TAZ via METTL3-m6A-YTHDF1". Cellular and Molecular Gastroenterology and Hepatology. 19 (1) 101417
Nirogacestat
Biochemical changes to RNA
this mark can also increase translational efficiency. The m6A "reader" YTHDF1 induces the association of the modified mRNA with the ribosome. Furthermore
Epitranscriptome
Set of all modifications of viral transcripts
within the nucleus. In the cytoplasm, the reading duties are carried out by YTHDF1, YTHDF2, and YTHDF3. The proteins ALKBH5 and FTO remove the m6A modification
Viral_epitranscriptome
Q86U90 18464 YTHDC1 HGNC:30626; Q96MU7 18465 YTHDC2 HGNC:24721; Q9H6S0 18466 YTHDF1 HGNC:15867; Q9BYJ9 18467 YTHDF2 HGNC:31675; Q9Y5A9 18468 YTHDF3 HGNC:26465;
List of human protein-coding genes 9
List_of_human_protein-coding_genes_9
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