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N6 METHYLADENOSINE

  • N6-Methyladenosine
  • Modification in mRNA, DNA

    N6-Methyladenosine (m6A) was originally identified and partially characterised in the 1970s, and is an abundant modification in mRNA and DNA. It is found

    N6-Methyladenosine

    N6-Methyladenosine

    N6-Methyladenosine

  • Epitranscriptome
  • Biochemical changes to RNA

    The most common and well-understood mRNA modification at present is N6-Methyladenosine (m6A), which has been observed to occur an average of three times

    Epitranscriptome

    Epitranscriptome

  • YTHDF2
  • Protein-coding gene in humans

    YTH N6-methyladenosine RNA binding protein 2 is a protein that in humans is encoded by the YTHDF2 gene. This gene encodes a member of the YTH (YT521-B

    YTHDF2

    YTHDF2

    YTHDF2

  • MRNA (2'-O-methyladenosine-N6-)-methyltransferase
  • Enzyme

    In enzymology, a mRNA (2'-O-methyladenosine-N6-)-methyltransferase (EC 2.1.1.62) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine

    MRNA (2'-O-methyladenosine-N6-)-methyltransferase

    MRNA_(2'-O-methyladenosine-N6-)-methyltransferase

  • Chuan He
  • Chinese-American chemical biologist

    subsequently discovered the first RNA demethylase that oxidatively reverses N6-methyladenosine (m6A) methylation in mammalian messenger RNA (mRNA) in 2011. The existence

    Chuan He

    Chuan He

    Chuan_He

  • Viral epitranscriptome
  • Set of all modifications of viral transcripts

    Nagaraja; Wu, Li (March 2019). "HIV-1 envelope proteins up-regulate N6-methyladenosine levels of cellular RNA independently of viral replication". Journal

    Viral epitranscriptome

    Viral_epitranscriptome

  • N6-Cyclopentyladenosine
  • Chemical compound

    receptors and has been used to derive a large family of derivatives. N6-Methyladenosine Williams M, Braunwalder A, Erickson TJ (February 1986). "Evaluation

    N6-Cyclopentyladenosine

    N6-Cyclopentyladenosine

    N6-Cyclopentyladenosine

  • FTO gene
  • Protein-coding gene in the species Homo sapiens

    3-methyluridine in single-stranded RNA, with low efficiency. The nucleoside N6-methyladenosine (m6A), an abundant modification in RNA, was then found to be a major

    FTO gene

    FTO gene

    FTO_gene

  • Xiao Wang
  • Chinese-born biochemist

    Guerrero, P Xie, E He, B Shen, C He. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. elife 2017,6, e31311 H Shi, X Wang, Z Lu, B S Zhao

    Xiao Wang

    Xiao_Wang

  • Methylation
  • Chemical process in which a methyl (CH3) group is covalently attached to a molecule

    before DNA methylation in the early forms of life evolving on earth. N6-methyladenosine (m6A) is the most common and abundant methylation modification in

    Methylation

    Methylation

  • METTL3
  • Gene encoding part of N6-adenosine-methyltransferase

    methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine (m6A). METTL3 forms the m6 a methyltransferase complex with METTL14

    METTL3

    METTL3

    METTL3

  • Chlamydomonas reinhardtii
  • Species of alga

    chlamylibrary.org/. The genome of C. reinhardtii has been shown to contain N6-Methyladenosine (m6A), a mark common in prokaryotes but much rarer in eukaryotes.

    Chlamydomonas reinhardtii

    Chlamydomonas reinhardtii

    Chlamydomonas_reinhardtii

  • RNA Modification Base
  • Post-transcriptional RNA modification database

    sequencing. It contains numerous examples of modifications such as N6-methyladenosine, pseudouridine, 5-methylcytosine, 2′-O-methylation and ~3130 other

    RNA Modification Base

    RNA_Modification_Base

  • RBM15
  • Protein-coding gene in humans

    gene. It is an RNA-binding protein that acts as a key regulator of N6-Methyladenosine (m6A) methylation of RNAs. GRCh38: Ensembl release 89: ENSG00000162775

    RBM15

    RBM15

    RBM15

  • DNA methylation
  • Biological process

    hosted on the UCSC Genome Browser MethDB DNA Methylation database N6-Methyladenosine Protein methylation Methylenetetrahydrofolate reductase deficiency

    DNA methylation

    DNA methylation

    DNA_methylation

  • Rhein (molecule)
  • Chemical compound

    protein, an enzyme responsible for removing the methylation from N6-methyladenosine in nucleic acids. The pharmacokinetics of rhein have not been intensively

    Rhein (molecule)

    Rhein (molecule)

    Rhein_(molecule)

  • RNA editing
  • Molecular process

    identify m5C modifications on mRNA instead of the original target N6-methyladenosine. The easy switch between different modifications as target is made

    RNA editing

    RNA editing

    RNA_editing

  • Nucleic acid notation
  • Universal notation of DNA nucleotides

    it is written with a subscript. As a result, m6A means N6-methyladenosine and m6 2A means N6-dimethyladenosine. The same modification at separate sites

    Nucleic acid notation

    Nucleic_acid_notation

  • Small nucleolar RNA
  • Class of small RNA molecules

    splicing. More recently, SNORD90 has been suggested to be able to guide N6-methyladenosine (m6A) modifications onto target RNA transcripts. More specifically

    Small nucleolar RNA

    Small_nucleolar_RNA

  • Epigenetics
  • Study of DNA modifications that do not change its sequence

    even cytoplasmic (structural) heritable states. RNA methylation of N6-methyladenosine (m6A) as the most abundant eukaryotic RNA modification has recently

    Epigenetics

    Epigenetics

    Epigenetics

  • Epitranscriptomic sequencing
  • seven major classes of chemical modifications found in RNA molecules: N6-methyladenosine, 2'-O-methylation, N6,2'-O-dimethyladenosine, 5-methylcytidine,

    Epitranscriptomic sequencing

    Epitranscriptomic sequencing

    Epitranscriptomic_sequencing

  • YTHDF1
  • Protein-coding gene in humans

    member 1 is a protein that in humans is encoded by the YTHDF1 gene. N6-Methyladenosine GRCh38: Ensembl release 89: ENSG00000149658 – Ensembl, May 2017 GRCm38:

    YTHDF1

    YTHDF1

    YTHDF1

  • Transfection
  • Process of introducing nucleic acids into eukaryotic cells

    Eukaryotic mRNA contains chemically modified nucleotides such as N6-methyladenosine, 5-methylcytidine, and 2'-O-methylated nucleotides. Although only

    Transfection

    Transfection

  • Five-prime cap
  • Specially altered nucleotide on the 5' end of pre-mRNA

    (m7G)ppp(Am)[pN]n), it can be further methylated at the N6 methyl position to form N6-methyladenosine, resulting in 5′(m7G)ppp(N6Am)[pN]n. For capping with

    Five-prime cap

    Five-prime_cap

  • AlkB
  • Protein in E. coli

    humans, is the first identified RNA demethylase. It demethylates N6-methyladenosine in mRNA. There is also another very different protein called AlkB

    AlkB

    AlkB

  • HNRNPA2B1
  • Protein-coding gene in the species Homo sapiens

    BioGPS More reference expression data Gene ontology Molecular function N6-methyladenosine-containing RNA binding pre-mRNA intronic binding miRNA binding single-stranded

    HNRNPA2B1

    HNRNPA2B1

    HNRNPA2B1

  • Y box binding protein 1
  • Protein-coding gene in the species Homo sapiens

    RNA binding protein that stabilises messenger RNAs modified with N6-methyladenosine. YBX1 is a potential drug target in cancer therapy. YB-1 helps the

    Y box binding protein 1

    Y box binding protein 1

    Y_box_binding_protein_1

  • METTL16
  • Protein-coding gene in the species Homo sapiens

    METTL16 gene. DNA/RNA methyltransferase m6A methyltransferase complex N6-Methyladenosine (m6A) GRCh38: Ensembl release 89: ENSG00000127804 – Ensembl, May 2017

    METTL16

    METTL16

    METTL16

  • Chromosome 8
  • Human chromosome

    WRN: Werner syndrome XKR9: encoding protein Xk related 9 YTHDF3: YTH N6-methyladenosine RNA binding protein 3 ZFP41: encoding protein ZFP41 zinc finger protein

    Chromosome 8

    Chromosome 8

    Chromosome_8

  • WTAP (gene)
  • Protein that in humans is encoded by the WTAP gene

    function protein binding Cellular component nuclear membrane nucleus RNA N6-methyladenosine methyltransferase complex nuclear speck nucleoplasm cytoplasm Biological

    WTAP (gene)

    WTAP (gene)

    WTAP_(gene)

  • ZC3H13
  • Protein-coding gene in the species Homo sapiens

    binding Cellular component nuclear speck nucleus nucleoplasm RNA N6-methyladenosine methyltransferase complex Biological process mRNA processing multicellular

    ZC3H13

    ZC3H13

    ZC3H13

  • Biricodar
  • Pharmaceutical drug

    Xu K, Zhang Q, Chen M, Li B, Wang N, Li C, et al. (April 2022). "N6-methyladenosine modification regulates imatinib resistance of gastrointestinal stromal

    Biricodar

    Biricodar

    Biricodar

  • Kumaravel Somasundaram
  • Indian cancer biologist( Born: 1962)

    Somasundaram, Kumaravel (January 2018). "mRNA Traffic Control Reviewed: N6-Methyladenosine (m6 A) Takes the Driver's Seat". BioEssays. 40 (1) 1700093. doi:10

    Kumaravel Somasundaram

    Kumaravel_Somasundaram

  • CBLL1
  • Protein-coding gene in humans

    ligase complex nucleus nucleoplasm cytosol nuclear speck cytoplasm RNA N6-methyladenosine methyltransferase complex Biological process positive regulation of

    CBLL1

    CBLL1

    CBLL1

  • HNRNPC
  • Protein-coding gene in the species Homo sapiens

    polymerase II cis-regulatory region sequence-specific DNA binding N6-methyladenosine-containing RNA binding poly(U) RNA binding mRNA 3'-UTR binding protein

    HNRNPC

    HNRNPC

    HNRNPC

  • YTHDC2
  • Protein-coding gene in humans

    nucleic acid binding ATP-dependent activity, acting on RNA RNA binding N6-methyladenosine-containing RNA binding 3'-5' RNA helicase activity Cellular component

    YTHDC2

    YTHDC2

    YTHDC2

  • Foam cell
  • Fat-laden M2 macrophages seen in atherosclerosis

    adhesion molecule 1 (VCAM-1). METTL3 is a gene responsible for mediating N6-methyladenosine RNA methylation, playing a critical role in the regulation of immune

    Foam cell

    Foam cell

    Foam_cell

  • METTL14
  • Protein-coding gene in the species Homo sapiens

    (February 2014). "A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation". Nat. Chem. Biol. 10 (2): 93–5. doi:10.1038/nchembio

    METTL14

    METTL14

    METTL14

  • HITS-CLIP
  • Method used in molecular biology

    generated, including those for PTB, RbFox2, SFRS1, hnRNP C, and even N6-Methyladenosine (m6A) mRNA modifications. HITS-CLIP of the RNA-binding protein Argonaute

    HITS-CLIP

    HITS-CLIP

  • Epigenomics
  • Field of study

    direct detection of modified nucleotide in the DNA template including N6-methyladenosine, 5-methylcytosine and 5-hydroxylcytosine. These various modifications

    Epigenomics

    Epigenomics

  • Cycloleucine
  • Chemical compound

    when compared to control hepatocytes. In a 2015 study on the role of N6-methyladenosine (m6A) demethylation on adipogenesis, researchers treated porcine adipocytes

    Cycloleucine

    Cycloleucine

    Cycloleucine

  • EIF3D
  • Protein-coding gene in the species Homo sapiens

    cycle regulation, and previous research demonstrated it can act as a N6-Methyladenosine reader on mRNAs. Eukaryotic initiation factor 3 (eIF3) GRCh38: Ensembl

    EIF3D

    EIF3D

    EIF3D

  • Yiliang Ding
  • Chinese scientist

    Chuan He; Zheng, Guanqun; Dai, Qing; Liu, Nian (February 2015). "N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions"

    Yiliang Ding

    Yiliang Ding

    Yiliang_Ding

  • YZG-331
  • Pharmaceutical compound

    YZG-331, also known as N6-[(S)-1-(phenyl)propyl]adenosine, is an adenosine receptor agonist which is or was under investigation for the potential treatment

    YZG-331

    YZG-331

    YZG-331

  • YTH protein domain
  • Protein domain

    RNA binding. The YTH domain proteins also serve as readers for the N6-methyladenosine (m6A) mRNA modification by scanning the mRNA to find the modified

    YTH protein domain

    YTH_protein_domain

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    and that the RNA is found to be post-translationally modified by N6-methyladenosine (m6A) on its 5' ends or RNA acetylation ac4C. Recent work has shown

    Stress granule

    Stress granule

    Stress_granule

  • YTHDC1
  • Protein-coding gene in humans

    influence alternative splicing of tumour-related genes such as CD44. N6-Methyladenosine ENSG00000083896 GRCh38: Ensembl release 89: ENSG00000275272, ENSG00000083896

    YTHDC1

    YTHDC1

    YTHDC1

  • Nucleic acid modification databases
  • Meyer, KD; Jaffrey, SR (April 2014). "The dynamic epitranscriptome: N6-methyladenosine and gene expression control". Nature Reviews Molecular Cell Biology

    Nucleic acid modification databases

    Nucleic_acid_modification_databases

  • Potyviridae
  • Family of viruses

    Zhao, Mingmin (October 2022). "AlkB RNA demethylase homologues and N6 -methyladenosine are involved in Potyvirus infection". Molecular Plant Pathology.

    Potyviridae

    Potyviridae

    Potyviridae

  • Small nucleolar RNA SNORD90
  • RNA family

    MNAB/OR1K1 gene. There is evidence that SNORD90 is involved in guiding N6-methyladenosine (m6A) modifications onto target RNA transcripts. Specifically, SNORD90

    Small nucleolar RNA SNORD90

    Small nucleolar RNA SNORD90

    Small_nucleolar_RNA_SNORD90

  • Sipagladenant
  • Pharmaceutical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Sipagladenant

    Sipagladenant

    Sipagladenant

  • YTHDF3
  • Protein-coding gene in humans

    protein 3 is a protein that in humans is encoded by the YTHDF3 gene. N6-Methyladenosine GRCh38: Ensembl release 89: ENSG00000185728 – Ensembl, May 2017 GRCm38:

    YTHDF3

    YTHDF3

    YTHDF3

  • Xanthinuria
  • Medical condition

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Xanthinuria

    Xanthinuria

    Xanthinuria

  • UTRdb
  • ADAR enzyme m6A modifications: marking mRNA modifications related to N6-methyladenosine UTRdb 2.0 provides a flexible web interface that allows users to select

    UTRdb

    UTRdb

  • AlkB homolog 5, RNA demethylase
  • Protein-coding gene in the species Homo sapiens

    demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation". J. Biol. Chem. 289 (25): 17299–311. doi:10.1074/jbc

    AlkB homolog 5, RNA demethylase

    AlkB homolog 5, RNA demethylase

    AlkB_homolog_5,_RNA_demethylase

  • Adenosine diphosphate
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Adenosine diphosphate

    Adenosine diphosphate

    Adenosine_diphosphate

  • Phenolphthalein
  • pH indicator that turns pink in basic solution

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Phenolphthalein

    Phenolphthalein

    Phenolphthalein

  • 5′-(N-Ethylcarboxamido)adenosine
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    5′-(N-Ethylcarboxamido)adenosine

    5′-(N-Ethylcarboxamido)adenosine

    5′-(N-Ethylcarboxamido)adenosine

  • Propolis
  • Resinous mixture produced by honey bees

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Propolis

    Propolis

    Propolis

  • 8-Bromotheophylline
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    8-Bromotheophylline

    8-Bromotheophylline

    8-Bromotheophylline

  • Tozadenant
  • Pharmaceutical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Tozadenant

    Tozadenant

    Tozadenant

  • MSX-2
  • Selective adenosine A2A receptor antagonist

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    MSX-2

    MSX-2

    MSX-2

  • Adenosine receptor antagonist
  • Class of drugs

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Adenosine receptor antagonist

    Adenosine_receptor_antagonist

  • Vipadenant
  • Pharmaceutical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Vipadenant

    Vipadenant

    Vipadenant

  • Inosinic acid
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Inosinic acid

    Inosinic acid

    Inosinic_acid

  • Allopurinol
  • Medication

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Allopurinol

    Allopurinol

    Allopurinol

  • Single-cell sequencing
  • Examines sequence information from individual cells

    including 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 6-methyladenosine (6mA), and 4-methylcytosine (4mC). In eukaryotes, especially animals

    Single-cell sequencing

    Single-cell_sequencing

  • Ciforadenant
  • Pharmaceutical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Ciforadenant

    Ciforadenant

    Ciforadenant

  • Purine
  • Heterocyclic aromatic organic compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Purine

    Purine

    Purine

  • Inosine
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Inosine

    Inosine

    Inosine

  • Cytosine
  • Chemical compound in nucleic acids

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Cytosine

    Cytosine

    Cytosine

  • Nucleoside
  • Any of several glycosylamines comprising a nucleobase and a sugar molecule

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Nucleoside

    Nucleoside

    Nucleoside

  • Lu AA41063
  • Selective adenosine A2A receptor antagonist

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Lu AA41063

    Lu AA41063

    Lu_AA41063

  • Phytic acid
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Phytic acid

    Phytic acid

    Phytic_acid

  • Pyrimidine
  • Aromatic compound (C4H4N2)

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Pyrimidine

    Pyrimidine

  • 3-Chlorostyrylcaffeine
  • Adenosine A2A receptor antagonist and MAO-B inhibitor

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    3-Chlorostyrylcaffeine

    3-Chlorostyrylcaffeine

    3-Chlorostyrylcaffeine

  • Pharmacology of ethanol
  • Pharmacodynamics and pharmacokinetics of ethanol

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Pharmacology of ethanol

    Pharmacology of ethanol

    Pharmacology_of_ethanol

  • Purine metabolism
  • Chemical reactions and pathways involving lysis of purine nucleotides

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Purine metabolism

    Purine_metabolism

  • Lu AA47070
  • Adenosine A2A receptor antagonist for Parkinson's disease

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Lu AA47070

    Lu AA47070

    Lu_AA47070

  • Uric acid
  • Organic compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Uric acid

    Uric_acid

  • Guanosine triphosphate
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Guanosine triphosphate

    Guanosine triphosphate

    Guanosine_triphosphate

  • Pentoxifylline
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Pentoxifylline

    Pentoxifylline

    Pentoxifylline

  • Febuxostat
  • Chemical compound, medication to treat gout

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Febuxostat

    Febuxostat

    Febuxostat

  • Guanine
  • Chemical compound of DNA and RNA

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Guanine

    Guanine

    Guanine

  • Adenosine
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Adenosine

    Adenosine

    Adenosine

  • Alcohol (drug)
  • Active ingredient in fermented drinks

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Alcohol (drug)

    Alcohol (drug)

    Alcohol_(drug)

  • Ticagrelor
  • Coronary medication

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Ticagrelor

    Ticagrelor

    Ticagrelor

  • Theobromine
  • Bitter alkaloid of the cacao plant

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Theobromine

    Theobromine

    Theobromine

  • Inositol
  • Carbocyclic sugar

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Inositol

    Inositol

    Inositol

  • Apigenin
  • Chemical in plants

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Apigenin

    Apigenin

    Apigenin

  • Kaempferol
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Kaempferol

    Kaempferol

    Kaempferol

  • Xanthine
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Xanthine

    Xanthine

    Xanthine

  • Adenosinergic
  • Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Adenosinergic

    Adenosinergic

  • Paraxanthine
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Paraxanthine

    Paraxanthine

    Paraxanthine

  • MSX-4
  • Selective adenosine A2A receptor antagonist

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    MSX-4

    MSX-4

    MSX-4

  • Theophylline/ephedra/hydroxyzine
  • Drug used for treatment of asthma

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Theophylline/ephedra/hydroxyzine

    Theophylline/ephedra/hydroxyzine

  • Caffeine
  • Central nervous system stimulant

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Caffeine

    Caffeine

    Caffeine

  • Ticlopidine
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Ticlopidine

    Ticlopidine

    Ticlopidine

  • Adenosine monophosphate
  • Chemical compound

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Adenosine monophosphate

    Adenosine monophosphate

    Adenosine_monophosphate

  • Ribose
  • Group of simple sugar and carbohydrate compounds

    Agonists: 8-Aminoadenine Adenine P1 (adenosine) Agonists: 2-(1-Hexynyl)-N-methyladenosine 2-Cl-IB-MECA 2-Chloroadenosine 2'-MeCCPA 4'-O-β-D-Glucosyl-9-O-(6'

    Ribose

    Ribose

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