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Chemical compound
5α-Dihydroprogesterone (5α-DHP, allopregnanedione, or 5α-pregnane-3,20-dione) is an endogenous progestogen and neurosteroid that is synthesized from progesterone
5α-Dihydroprogesterone
Endogenous inhibitory neurosteroid
effects. (5α-dihydroprogesterone is reduced to produce allopregnanolone, and progesterone is reduced to produce 5α-dihydroprogesterone). In addition
Allopregnanolone
Index of chemical compounds with the same name
(pregn-5-en-3β-ol-20-one) Pregnenolone (medication) Pregnenolone sulfate 3β-Dihydroprogesterone (pregn-4-en-3β-ol-20-one) 3α-Dihydroprogesterone
Pregnenolone_(disambiguation)
Chemical compound
20α-Dihydroprogesterone (20α-DHP), also known as 20α-hydroxyprogesterone (20α-OHP), is a naturally occurring, endogenous progestogen. It is a metabolite
20α-Dihydroprogesterone
Chemical compound
3α-Dihydroprogesterone (3α-DHP), also known as 3α-hydroxyprogesterone, as well as pregn-4-en-3α-ol-20-one, is an endogenous neurosteroid. It is biosynthesized
3α-Dihydroprogesterone
Chemical compound
3β-Dihydroprogesterone (3β-DHP), also known as 3β-hydroxyprogesterone, or pregn-4-en-3β-ol-20-one (4-pregnenolone, δ4-pregnenolone), is an endogenous
3β-Dihydroprogesterone
Chemical compound
20β-Dihydroprogesterone (20β-DHP), also known as 20β-hydroxyprogesterone (20β-OHP), is an endogenous metabolite of progesterone which is formed by 20β-hydroxysteroid
20β-Dihydroprogesterone
neurosteroids 3α-Dihydroprogesterone (3α-DHP): pregn-4-en-3α-ol-20-one – GABAA receptor positive allosteric modulator 5α-Dihydroprogesterone (5α-DHP; allopregnanedione):
List_of_neurosteroids
Chemical compound
5β-Dihydroprogesterone (5β-DHP, pregnanedione, or 5β-pregnane-3,20-dione) is an endogenous neurosteroid and an intermediate in the biosynthesis of pregnanolone
5β-Dihydroprogesterone
Chemical compound
5β-androstanol. 17β-Ethyletiocholanes, or 5β-pregnanes, include 5β-dihydroprogesterone, pregnanolone, and epipregnanolone, as well as pregnanediol and pregnanetriol
Etiocholane
Group of cell surface receptors for progesterone
progesterone and allopregnanolone. The progesterone active metabolites 5α-dihydroprogesterone, also a progestogen, and allopregnanolone, which are positive allosteric
Membrane progesterone receptor
Membrane_progesterone_receptor
Sex hormone
in this pathway include 3α-dihydroprogesterone, 3β-dihydroprogesterone, 20α-dihydroprogesterone, and 20β-dihydroprogesterone, as well as various combination
Progesterone
Steroid hormone that activates the progesterone receptor
(very weak), 20α-dihydroprogesterone (20α-DHP), 20β-dihydroprogesterone (20β-DHP), 5α-dihydroprogesterone (5α-DHP), 5β-dihydroprogesterone (5β-DHP) (very
Progestogen
Enzyme family
5α-Cholestanone Progesterone → 5α-Dihydroprogesterone 3α-Dihydroprogesterone → Allopregnanolone 3β-Dihydroprogesterone → Isopregnanolone Deoxycorticosterone
5α-Reductase
Chemical compound
Nicardipine Octicizer Permethrin Phenobarbital Phenytoin Pregnanedione (5β-dihydroprogesterone) Reserpine TCPOBOP Telmisartan Tolnaftate Troglitazone Valproic acid
Fenbendazole
Class of enzymes
example, 5α-dihydroprogesterone is the product of the reduction of progesterone: Progesterone + NADPH H+ H+ 5α-Dihydroprogesterone + NADP+ The
Cholestenone_5alpha-reductase
Class of medications
reduction, 5α-reductase isoforms I and II reduce progesterone to 5α-dihydroprogesterone (5α-DHP) and deoxycorticosterone to dihydrodeoxycorticosterone (DHDOC)
5α-Reductase_inhibitor
Chemical compound
Cholesterol sulfate, or cholest-5-en-3β-ol sulfate, is an endogenous steroid and the C3β sulfate ester of cholesterol. It is formed from cholesterol by
Cholesterol_sulfate
Alkaloid responsible for the pungency of black pepper
dichloromethane or ethanol. The amount of piperine varies from 1–2% in long pepper, to 5–10% in commercial white and black peppers. Piperine can also be prepared by
Piperine
Chemical compound
5α-Pregnan-17α-ol-3,20-dione, also known as 17α-hydroxy-dihydroprogesterone (17-OH-DHP) is an endogenous steroid, a metabolite of 17α-hydroxyprogesterone
5α-Pregnan-17α-ol-3,20-dione
Chemical compound
activity similarly to trengestone. 20α-Dihydrodydrogesterone 20α-Dihydroprogesterone Dixon R, Tormey P, Darragh A (March 1975). "Disposition of the retro-steroid
20α-Dihydrotrengestone
Chemical compound
24S-Hydroxycholesterol (24S-HC), also known as cholest-5-ene-3,24-diol or cerebrosterol, is an endogenous oxysterol produced by neurons in the brain to
24S-Hydroxycholesterol
Chemical compound
a TRPM3 channel activator. Isopregnanolone 3β-Dihydroprogesterone Pregnanolone 5α-Dihydroprogesterone 3β-Androstanediol Neurosteroids and Brain Function
Epipregnanolone
Compounds that alter neuronal activity
Watanabe H, Costa E, Guidotti A (February 2001). "Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social
Neurosteroid
Chemical compound
20α,22R-Dihydroxycholesterol, or (3β)-cholest-5-ene-3,20,22-triol is an endogenous, metabolic intermediate in the biosynthesis of the steroid hormones
20α,22R-Dihydroxycholesterol
Synthetic, orally active anabolic steroid
19-Nor-5-androstenedione, also known as estr-5-ene-3,17-dione, is a synthetic, orally active anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone
19-Nor-5-androstenedione
Pharmaceutical combination
"Effects of low-dose norethindrone acetate plus ethinyl estradiol (0.5 mg/2.5 microg) in women with postmenopausal symptoms: updated analysis of three
Ethinylestradiol/norethisterone acetate
Ethinylestradiol/norethisterone_acetate
Injectable form of birth control
Progesterone, via transformation into neurosteroids such as 5α-dihydroprogesterone, 5β-dihydroprogesterone, allopregnanolone, and pregnanolone (catalyzed by the
Medroxyprogesterone_acetate
Chemical compound
of Animal Behaviour. PHI Learning Pvt. Ltd. pp. 296–. ISBN 978-81-203-4519-5. Wilson M (2005). "The Skin and Its Indigenous Microbiota". Microbial Inhabitants
Androstadienol
Chemical compound
Dehydroandrosterone (DHA), or 5-dehydroandrosterone (5-DHA), also known as isoandrostenolone, as well as androst-5-en-3α-ol-17-one, is an endogenous androgen
Dehydroandrosterone
Chemical compound
Ethinylandrostenediol (developmental code name SKF-2856), also known as 17α-ethynyl-5-androstenediol, is a synthetic estrogen, progestogen, and androgen which was
Ethinylandrostenediol
Chemical compound
Solubility Data (Second ed.). CRC Press. pp. 1209–. ISBN 978-1-4398-0246-5. Agarwal OP (2006). Natural Products. Krishna Prakashan Media. pp. 298–.
Epiandrosterone
Chemical compound
USAN; former tentative brand name Lutisan; also known as 17α-ethynylestr-5-en-17β-ol) is a steroidal progestin of the 19-nortestosterone group that was
Cingestol
Primary male sex hormone
in females. The plasma protein binding of testosterone is 98.0 to 98.5%, with 1.5 to 2.0% free or unbound. It is bound 65% to sex hormone-binding globulin
Testosterone
Chemical compound
BANTooltip British Approved Name. 11α-Hydroxyprogesterone 5α-Dihydroprogesterone 20-Dihydroprogesterone 11-Deoxycorticosterone 11-Deoxycortisol 17α-Methylprogesterone
17α-Hydroxyprogesterone
Chemical compound
11beta-hydroxysteroid dehydrogenase type 1". J. Steroid Biochem. Mol. Biol. 105 (1–5): 159–65. doi:10.1016/j.jsbmb.2006.11.021. PMID 17624766. S2CID 54408683.
7α-Hydroxyepiandrosterone
Chemical compound
Androstenediol sulfate, also known as androst-5-ene-3β,17β-diol 3β-sulfate, is an endogenous, naturally occurring steroid and a urinary metabolites of
Androstenediol_sulfate
Chemical compound
similarly to dydrogesterone, but is far less potent in comparison. 20α-Dihydroprogesterone 20α-Dihydrotrengestone Bińkowska M, Woroń J (June 2015). "Progestogens
20α-Dihydrodydrogesterone
Chemical compound
sulfated derivative, pregnenolone sulfate, is water-soluble. 3β-Dihydroprogesterone (pregn-4-en-3β-ol-20-one) is an isomer of pregnenolone in which the
Pregnenolone
Anabolic steroid
differently and are less sensitive to androgens. While some literature report a 5 fold higher potency, two other scientific reviews report a 3 fold higher potency
Trenbolone
extranuclear steroid receptor signaling to clinical medicine". Hormones & Cancer. 5 (3): 140–145. doi:10.1007/s12672-014-0179-9. PMC 4040225. PMID 24752388. Hammes
Membrane_steroid_receptor
Chemical compound
sulfate (16α-OH-DHEA-S), also known as 16α-hydroxy-17-oxoandrost-5-en-3β-yl sulfate, is an endogenous, naturally occurring steroid and a metabolic
16α-Hydroxy-DHEA_sulfate
Pharmaceutical compound
4-PIOL, also known as 5-(4-piperidyl)isoxazol-3-ol, is a GABAA receptor agonist that was derived from THIP (gaboxadol). It is a non-ring-fused analogue
4-PIOL
Chemical compound
dehydrogenase, with 5β-dihydroprogesterone occurring as a metabolic intermediate. The elimination half-life of pregnanolone is between 0.9 and 3.5 hours. Pregnanolone
Pregnanolone
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Androstadienone
Chemical compound
enzymes 5α-reductase and 3β-hydroxysteroid dehydrogenase (with 5α-dihydroprogesterone as the intermediate in this two-step transformation) and can be reversibly
Isopregnanolone
Chemical compound
progesterone 3-acetyl enol ether into 3α-dihydroprogesterone and/or 3β-dihydroprogesterone. 3β-Dihydroprogesterone has been reported to possess about the
Progesterone 3-acetyl enol ether
Progesterone_3-acetyl_enol_ether
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Tetrahydrocortisone
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
5β-Dihydrotestosterone
Chemical compound
Progesterone receptor Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone
Asoprisnil
Chemical compound
Tigestol (INN, USAN), also known as 17α-ethynylestr-5(10)-en-17β-ol, is a steroidal progestin of the 19-nortestosterone group that was developed by Organon
Tigestol
Chemical compound
19-Nor-5-androstenediol, also known as estr-5-ene-3β,17β-diol, is a synthetic, orally active anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone
19-Nor-5-androstenediol
Class of steroid hormones
hormones are cortisol (C 21H 30O 5), corticosterone (C 21H 30O 4), cortisone (C 21H 28O 5) and aldosterone (C 21H 28O 5) (cortisone and aldosterone are
Corticosteroid
Pharmaceutical compound
Thiomuscimol, also known as 5-aminomethyl-3-isothiazol, is a synthetic GABAA receptor agonist which is structurally related to the naturally occurring
Thiomuscimol
Endogenous weak androgen
dehydroepiandrosterone (DHEA). It is closely related to androstenediol (androst-5-ene-3β,17β-diol). Androstenedione is a precursor of testosterone and other
Androstenedione
Medication to treat gastroesophageal reflux disease and other conditions
respiratory tract infection (2%), cough (1%) Gastrointestinal: abdominal pain (5%), diarrhea (4%), nausea (4%), vomiting (3%), flatulence (3%), acid regurgitation
Omeprazole
Chemical compound
formulated at a dose of 50–100 mg in combination with a "trace" dose of 0.25–0.5 mg quinestrol as a long-lasting, once-a-month combined oral contraceptive
Cymegesolate
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
16α-Hydroxyandrostenedione
Corticosteroid medication
antitumor treatments. Dexamethasone can increase the antiemetic effect of 5-HT3 receptor antagonists, such as ondansetron. The exact mechanism of this
Dexamethasone
Chemical compound
stays the same. The decreased clearance is possibly from lower thyroxine 5-deiodinase activity in the peripheral tissue or decreased liver uptake of
Reverse_triiodothyronine
Medication
artery hypertension (PAH). Bosentan is available as film-coated tablets (62.5 mg or 125 mg) or as dispersible tablets for oral suspension (32 mg). Bosentan
Bosentan
Pharmaceutical compound
Thio-4-PIOL, also known as 5-(piperidin-4-yl)isothiazol-3-ol, is a GABAA receptor weak partial agonist or antagonist related to 4-PIOL. The drug acts
Thio-4-PIOL
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Androstenone
Chemical compound
Androstenetriol (AET, androst-5-ene-3β,7β,17β-triol, β-androstenetriol, or β-AET) is a steroid produced in the adrenal glands as a metabolite of dehydroepiandrosterone
Androstenetriol
Antiretroviral medication
efficacy. The structural key to this inhibition is the unsubstituted P2' 5-thiazolyl group of ritonavir; the unhindered nitrogen atom on this specific
Ritonavir
Chemical compound
Menopause and Postmenopause. pp. 43–52. doi:10.1007/978-94-011-7230-1_5. ISBN 978-94-011-7232-5. Fishman J, Martucci C (September 1980). "Biological properties
2-Methoxyestrone
Chemical compound
procedures". Tetrahedron. 20 (2): 357–372. doi:10.1016/S0040-4020(01)93223-5. ISSN 0040-4020. Raynaud JP, Philibert D, Azadian-Boulanger G (1974).
17α-Methyl-19-norprogesterone
Mammalian pheromone also found in truffles
3β-hydroxy steroids, including isopregnanolone, epipregnanolone, 3β-dihydroprogesterone, and 3β-androstanediol, which similarly do not act as such, in contrast
Androstenol
Chemical compound
Academic Press. pp. 541–567. doi:10.1016/B978-0-12-387817-5.00030-3. ISBN 978-0-12-387817-5. Maggi M (17 November 2011). Hormonal Therapy for Male Sexual
Cyproterone_acetate
Class of chemical compounds
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Adrenal_steroid
Human hormone
androsterone → 5α-androstane-3α,17β-diol → DHT. progesterone → 5α-dihydroprogesterone → allopregnanolone → 5α-pregnane-3α,17α-diol-20-one → androsterone
Dihydrotestosterone
Chemical compound
Progesterone receptor Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone
LG-2527
Antibiotic
shock syndrome with antibiotics". Expert Opin Pharmacother. 5 (8): 1701–10. doi:10.1517/14656566.5.8.1701. PMID 15264985. S2CID 24494787. Coyle EA (May 2003)
Clindamycin
Chemical compound
Progesterone receptor Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone
Chlormadinone_caproate
Chemical compound
affinity for the progesterone receptor, only about 12.5% of that of progesterone and about 2.5% of that of 19-norprogesterone in one assay. On the other
Gestronol
Chemical compound
Those Who Receive Oxacillin". Antimicrobial Agents and Chemotherapy. 60 (5): 3090–3095. doi:10.1128/AAC.03122-15. PMC 4862451. PMID 26976858. Bonow RO
Nafcillin
Medication and supplement
of cholesterol. Related steroids include pregnenolone sulfate, 3β-dihydroprogesterone (4-pregnenolone), progesterone, allopregnanolone, and pregnanolone
Pregnenolone_(medication)
Pharmaceutical combination
August 2024. "Beyaz." MPR - Obstetrician & Gynecologist Edition (2010): A.5. Academic Search Complete. EBSCO. Web. 11 October 2011. "Bayer Receives Approval
Drospirenone/ethinylestradiol/levomefolic acid
Drospirenone/ethinylestradiol/levomefolic_acid
Chemical compound
17α-diol-20-one; 5α-dihydroprogesterone (5α-DHP) is 5α-pregnane-3,20-dione, and allopregnanolone is 3α-hydroxy-dihydroprogesterone (3α-OH-DHP) or
5α-Pregnane-3α,17α-diol-20-one
5α-Pregnane-3α,17α-diol-20-one
Chemical compound
(7β-hydroxy-DHEA; 7β-OH-DHEA), also known as 3β,7β-dihydroxyandrost-5-ene-17-one, is an endogenous, naturally occurring steroid and a metabolite
7β-Hydroxy-DHEA
Class of drugs
THAZ Thio-THIP TPMPA trans-3-ACPBPA ZAPA Negative modulators: 5α-Dihydroprogesterone Bilobalide Loreclezole Picrotoxin (picrotin, picrotoxinin) Pregnanolone
GABA_analogue
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Pregnanediol_glucuronide
Opioid medication
intrathecal opioid because its lipophilic profile allows a quick onset of action (5–10 min) and intermediate duration of action (60–120 min). Spinal administration
Fentanyl
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Androsterone_glucuronide
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
Etiocholanolone
Explosive chemical compound
wax) and composition A-5 (98.5 to 99.1% RDX coated with 0.95 to 1.54% stearic acid). Composition B: Castable mixtures of 59.5% RDX and 39.4% TNT with
RDX
Chemical compound
Progesterone receptor Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone
Hydromadinone
Chemical compound
Progesterone receptor Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone
Telapristone
Chemical compound
21-Hydroxypregnenolone, also known as prebediolone, as well as 3β,21-dihydroxypregn-5-en-20-one, is a naturally occurring and endogenous pregnane steroid, and an
21-Hydroxypregnenolone
Chemical compound
Fluid". In Beier HM, Karlson P (eds.). Proteins and Steroids in Early Pregnancy. pp. 335–342. doi:10.1007/978-3-642-67890-5_22. ISBN 978-3-642-67892-9.
Megestrol_caproate
Calcium channel blocker medication
most commonly prescribed medication in the United States, with more than 5 million prescriptions. The approved uses are for the long-term treatment of
Nifedipine
Progestin medication
into 3α-dihydroprogesterone and/or 3β-dihydroprogesterone and then further metabolized into pregnanolones and pregnanediols. 3β-Dihydroprogesterone has been
Quingestrone
Vertebrate natural glucocorticoid hormone
irreversibly into 5-alpha tetrahydrocortisol (5-alpha THF) and 5-beta tetrahydrocortisol (5-beta THF), reactions for which 5-alpha reductase and 5-beta-reductase
Cortisol
Chemical compound
for Testosterone glucuronide (HMDB03193)". Human Metabolome Database, HMDB. 5.0. King C, Rios G, Green M, Tephly T (2000). "UDP-glucuronosyltransferases"
Testosterone_glucuronide
Combination drug
Ayerst, McKenna & Harrison Limited: Premarin Injectable, 20 mg. per vial of 5 c.c. General Practitioner. American Academy of General Practice. April 1962
Estrone/progesterone/testosterone
Estrone/progesterone/testosterone
Chemical compound
5-Androstenedione, also known as androst-5-ene-3,17-dione, is a prohormone of testosterone. The World Anti-Doping Agency prohibits its use in athletes
5-Androstenedione
Chemical compound
Progesterone receptor Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone
VOLT-02
Chemical compound
Meclizine reaches peak plasma concentration in about 1.5 hours and has an elimination half-life of 5–6 hours. Despite its relatively short half-life, the
Meclizine
Blood pressure medication
influence on the kinetics of telmisartan. Plasma protein binding is over 99.5%, mainly to albumin and alpha-1-acid glycoprotein. It has the longest half-life
Telmisartan
Chemical compound
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone
18-Oxocortisol
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5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
5 DIHYDROPROGESTERONE
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