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Buffer solution
Artificial cerebrospinal fluid (aCSF) is a buffer solution prepared with a composition similar to that of cerebrospinal fluid, that is used experimentally
Artificial cerebrospinal fluid
Artificial_cerebrospinal_fluid
Brain kept alive in vitro outside of a body
of various salts, or by submerging the brain in oxygenated artificial cerebrospinal fluid (CSF). It is the biological counterpart of brain in a vat. A
Isolated_brain
Laboratory method involving brain slices
tissue is initially sliced via a tissue slicer then immersed in artificial cerebrospinal fluid (aCSF) for stimulation and/or recording. The technique allows
Slice_preparation
Topics referred to by the same term
All-China Sports Federation American Clean Skies Foundation Artificial cerebrospinal fluid Atkinson Center for a Sustainable Future This disambiguation
ACSF
(February 2024). "Applied deep learning in neurosurgery: identifying cerebrospinal fluid (CSF) shunt systems in hydrocephalus patients". Acta Neurochirurgica
Artificial intelligence in healthcare
Artificial_intelligence_in_healthcare
State of steady internal conditions maintained by living things
partial pressure of carbon dioxide is detected as altered pH in the cerebrospinal fluid by central chemoreceptors (CNS) in the medulla oblongata of the brainstem
Homeostasis
Inflammation of the brain
symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid. Certain types are preventable with vaccines. Treatment may include
Encephalitis
Surgical operation on skull
lesionectomy; implantation of deep brain stimulation electrodes. Cerebrospinal fluid–related procedures: repair of CSF leaks; creation of CSF shunts;
Craniotomy
Central organ of the human nervous system
ventricular system, consisting of four interconnected ventricles in which cerebrospinal fluid is produced and circulated. Underneath the cerebral cortex are several
Human_brain
Autoimmune disease
by tests such as nerve conduction studies and examination of the cerebrospinal fluid. There are several subtypes based on the areas of weakness, results
Guillain–Barré_syndrome
Pakistani American neurosurgeon (1930–2008)
"Subcutaneus reservoir and pump for sterile access to ventricular cerebrospinal fluid". Lancet. 2 (7315): 983–984. doi:10.1016/s0140-6736(63)90681-0. PMID 14059058
Ayub_Ommaya
Hole or passage within the human body that allows fluids to move throughout it
increased intracranial pressure, a one-way valve is used to drain excess cerebrospinal fluid from the brain and carry it to other parts of the body. This valve
Shunt_(medical)
Structures within the human brain
third ventricle at the midline of the brain. As channels, they allow cerebrospinal fluid (CSF) produced in the lateral ventricles to reach the third ventricle
Interventricular foramina (neuroanatomy)
Interventricular_foramina_(neuroanatomy)
Measure of the level of acidity or basicity of an aqueous solution
both flavor and appearance. In living organisms, the pH of various body fluids, cellular compartments, and organs is tightly regulated to maintain a state
PH
Surgery used to treat abdominal aortic aneurysm
pressure, increased oxygenation, blood transfusion and cerebrospinal fluid drainage. Cerebrospinal fluid drainage is one of the adjunct methods used to reverse
Endovascular_aneurysm_repair
Medical imaging technique
Quantitative susceptibility mapping (QSM) Quantitative fluid flow MRI (i.e. some cerebrospinal fluid flow MRI) Magnetic resonance elastography (MRE) Magnetic
Magnetic_resonance_imaging
Medical treatment for cerebral edema
Effect of Reductive Ventricular Osmotherapy on the Osmolarity of Artificial Cerebrospinal Fluid and the Water Content of Cerebral Tissue Ex Vivo". Journal of
Osmotherapy
Drug for chronic pain
(FDA) approved ziconotide when delivered as an infusion into the cerebrospinal fluid using an intrathecal pump system.[citation needed] Due to the profound
Ziconotide
Increased pressure around the brain with no known cause
intracranial pressure is determined by the amount of brain tissue, cerebrospinal fluid (CSF) and blood inside the bony cranial vault. Three theories therefore
Idiopathic intracranial hypertension
Idiopathic_intracranial_hypertension
Medical condition
of 5-MTHF in their cerebrospinal fluid may be prescribed folinic acid, which efficiently penetrates the blood-cerebrospinal fluid barrier and helps restore
Autosomal recessive GTP cyclohydrolase I deficiency
Autosomal_recessive_GTP_cyclohydrolase_I_deficiency
Congenital malformation of the cerebellar vermis
space behind the cerebellum (the posterior fossa) are enlarged with cerebrospinal fluid. Most of those affected develop hydrocephalus within the first year
Dandy–Walker_malformation
Prion disease of the human brain
evaluation of sleep symptoms supported by advanced neuroimaging, cerebrospinal fluid assays, and genetic screening. The real-time quaking-induced conversion
Fatal_insomnia
Substance used to diagnose, cure, treat, or prevent disease
screening Tuberculin (Mantoux test) Intrathecal Injected into the cerebrospinal fluid within the spinal canal. Commonly used for chemotherapy and spinal
Medication
Family of conserved regulatory molecules
reported as 14-3-3 ligands. Elevated amounts of 14-3-3 protein in cerebrospinal fluid are usually a sign of rapid neurodegeneration; a common indicator
14-3-3_protein
Regulation of neurons by neurotransmitters
neuromodulators end up spending a significant amount of time in the cerebrospinal fluid (CSF), influencing (or "modulating") the activity of several other
Neuromodulation
Japanese actress (born 1975)
was withdrawing from performances of Chicago due to treatment for cerebrospinal fluid hypovolemia. "米倉涼子、27年在籍した事務所を円満退社し独立「自分らしく頑張っていきます」". ORICON NEWS
Ryoko_Yonekura
Species of protozoa
trophozoite stage is present, the flagellate form has been discovered in cerebrospinal fluid. To endure harsh environmental conditions, trophozoites transform
Naegleria_fowleri
Organelle found on eukaryotic cells
chemosensory functions. Motile cilia on ependymal cells move the cerebrospinal fluid through the ventricular system of the brain. Motile cilia are also
Cilium
Australian biomedical scientist
to 2020, contributing to fields including dental enamel research, cerebrospinal fluid biomarker discovery, and metastatic cancer resistance mechanisms
Jonathan_E._Mangum
Medical condition
uncoordinated movements, and evidence of viral infection in the cerebrospinal fluid (CSF). A tendency to abnormal bleeding has been reported in up to
Oropouche_fever
Inflammation of the entire cross-section of the spinal cord
defined sensory level Signs of inflammation (pleocytosis of the cerebrospinal fluid, or elevated immunoglobulin G, or evidence of inflammation on gadolinium-enhanced
Transverse_myelitis
Medical intervention
Facial nerve damage Dizziness or vertigo Taste changes Dural injury Cerebrospinal fluid leakage Intracranial complications such as brain abscess, subdural
Mastoidectomy
Retrieved 2023-12-13. Biofluid Mechanics Lab Laboratory for Biomedical Fluid Mechanics Biofluid Simulation and Modeling Heat Transfer Lab IIST The Technion
List of biofluid mechanics research groups
List_of_biofluid_mechanics_research_groups
Equilibrium between buoyancy and weight of an immersed object
approximately neutral buoyancy as a result of its suspension in cerebrospinal fluid. The actual mass of the human brain is about 1400 grams; however
Neutral_buoyancy
Condition in which a patient is aware but completely paralysed
move. If no mass or vascular lesion is present on the imaging scan, cerebrospinal fluid examination may be used to reveal an infectious or autoimmune root
Locked-in_syndrome
American chemist (born 1940)
professor emeritus. In 1992, Haley and a colleague, upon examining cerebrospinal fluid, reported levels of glutamine synthetase considerably higher in cases
Boyd_Haley
Organic acid
cells, the extracellular fluid immediately surrounding neurons strongly differs in composition from the blood or cerebrospinal fluid, being much richer with
Lactic_acid
Peptide hormone in humans
that patients with chronic neuropathic pain had significantly lower cerebrospinal-fluid β-endorphin concentrations than healthy controls. β-Endorphin release
Β-Endorphin
Medical condition
syndrome because lithium increases serotonin metabolites in the cerebrospinal fluid. There are several drug interactions with lithium. Interactions can
Lithium_toxicity
American neurosurgeon
grant to conduct a multi-center study evaluating the drainage of cerebrospinal fluid to treat of acute spinal cord injury. In 2010, he founded Excelsius
Nicholas_Theodore
Physiological nervous system response to increased intracranial pressure
(ICP). Since cerebrospinal fluid is located in an area surrounded by the skull, increased ICP consequently increases the pressure in the fluid itself. The
Cushing_reflex
Naturally recurring resting state of mind and body
faster rate than during an awake state, by increasing the flow of cerebrospinal fluid during sleep. The mechanism for this removal appears to be the glymphatic
Sleep
American right-to-die legal case
ex vacuo, a condition marked by enlarged ventricles filled with cerebrospinal fluid, because of this profound loss of cortical volume." Altenbernd, Chris
Terri_Schiavo_case
Absence of the sensation of weight
fluid shifts are thought to increase cerebrospinal fluid pressure (causing backaches), intracranial pressure (causing headaches), and inner ear fluid
Weightlessness
Inherited neurodegenerative disorder
Mutant huntingtin was detected and quantified for the first time in cerebrospinal fluid from HD mutation-carriers in 2015 using a novel "single-molecule
Huntington's_disease
Theories proposing consciousness as an electromagnetic phenomenon
norepinephrine modulates arteriolar vasomotion, which in turn drives ionic cerebrospinal-fluid (CSF) flow whose moving charges generate weak, structured electromagnetic
Electromagnetic theories of consciousness
Electromagnetic_theories_of_consciousness
Cognitive decline
causes such as hypothyroidism (an underactive thyroid). Fluid biomarkers detected in cerebrospinal fluid, and in blood can identify Alzheimer's disease. PET
Dementia
Bleeding within the skull
effectiveness in detecting bony fractures, vascular injuries, and cerebrospinal fluid (CSF) leaks. Despite its advantages, MRI (magnetic resonance imaging)
Intracranial_hemorrhage
Combination medication
Neprilysin also has a role in clearing the protein amyloid beta from the cerebrospinal fluid, and its inhibition by sacubitril has shown increased levels of AB1-38
Sacubitril/valsartan
British zoologist (1874–1941)
working at Davenport Military Hospital in Plymouth. Due to an outbreak of cerebrospinal fever amongst the troops, he improved cultivation methods to study meningococcus
Cresswell_Shearer
Biological fluid sampling technique
"The concentrations of free amino acids and other electrolytes in cerebrospinal fluid, in vivo dialysate of brain, and blood plasma of the dog". Journal
Microdialysis
Overview of and topical guide to the human brain
wake/sleep patterns Ventricular system – set of structures containing cerebrospinal fluid which bathes and cushions the brain and spinal cord within the skull
Outline_of_the_human_brain
perfluorocarbon emulsion not as a blood substitute, but rather as a cerebrospinal fluid (CSF) substitute. In order to increase oxygen delivery to the brains
Perfluorocarbon_emulsions
Pathogenic type of misfolded protein
was safe and reached "encouraging" concentrations in the brain and cerebrospinal fluid. While there is no known way to extend the life of a patient with
Prion
Infectious disease caused by Borrelia bacteria, spread by ticks
multiplex. Lymphocytic meningitis causes characteristic changes in the cerebrospinal fluid (CSF) and may be accompanied for several weeks by variable headache
Lyme_disease
Autoimmune disease
glands. Sjögren's disease is associated with increased levels in cerebrospinal fluid (CSF) of IL-1RA, an interleukin 1 antagonist. This suggests that
Sjögren's_disease
Medication for pain and fever
This metabolite has been detected in the brains of animals and cerebrospinal fluid of humans taking paracetamol. It is formed in the brain from another
Paracetamol
Deadly viral disease, transmitted through animals
after death. The diagnosis can also be made from saliva, urine, and cerebrospinal fluid samples, but this is not as sensitive or reliable as brain samples
Rabies
Medical condition
high levels of the amino acid, glycine, in bodily fluids and tissues, especially the cerebrospinal fluid. Severity of symptoms and outcomes correlate with
Glycine_encephalopathy
Chemical compound
clear the CNS reservoir, with ongoing trials monitoring changes in cerebrospinal fluid (CSF) viral DNA and neurocognitive function. Additional studies are
Baricitinib
Medical intervention
(failed back syndrome). Risks include damage to nerves or muscles, a cerebrospinal fluid leak, and typical surgical risks, such as infection or a failure
Minimally invasive spine surgery
Minimally_invasive_spine_surgery
understanding of how light interacts with matter. A study of proteins in cerebrospinal fluid indicates there are five subtypes of Alzheimer's disease, suggesting
2024_in_science
researched the use of this sensing technology in distinguishing cerebrospinal fluid from serum, for the diagnosis of bacterial sinusitis, conducting
C._William_Hanson
Infectious disease caused by poliovirus
it may be possible to identify poliovirus in the blood or in the cerebrospinal fluid. Poliovirus samples are further analysed using reverse transcription
Polio
used with imaging the nervous system: T1-weighted (T1W) images: Cerebrospinal fluid is dark. T1-weighted images are useful for visualizing normal anatomy
Magnetic resonance imaging of the brain
Magnetic_resonance_imaging_of_the_brain
Skin sore sustained by a vasculatory disease
used to decrease release of inflammatory cytokines, lower the amount of fluid leaking from capillaries and therefore prevent swelling, and prevent clotting
Venous_ulcer
Neurological impairment of voluntary muscle movement
magnum, sometimes causing hydrocephalus as a result of obstruction of cerebrospinal fluid outflow. Succinic semialdehyde dehydrogenase deficiency is an autosomal-recessive
Ataxia
blood–brain barrier A semipermeable membrane separating the blood from the cerebrospinal fluid, and constituting a barrier to the passage of cells, particles, and
Glossary_of_biology
Medical specialty of disorders which affect any portion of the nervous system
pituitary tumors, craniopharyngiomas, chordomas, and the repair of cerebrospinal fluid leaks. Ventricular endoscopy is used in the treatment of intraventricular
Neurosurgery
Thin astrocyte membrane surrounding the brain and spinal cord
substance entering the central nervous system from the blood or cerebrospinal fluid (CSF) must cross the glia limitans. The two different classifications
Glia_limitans
Species of bacterium
Youn, HS (July–August 2011). "Acinetobacter baumannii isolation in cerebrospinal fluid in a febrile neonate". The Turkish Journal of Pediatrics. 53 (4):
Acinetobacter_baumannii
Organ central to the nervous system
metabolites within the brain are cleared mostly by bulk flow of the cerebrospinal fluid within the glymphatic system instead of via venules like other parts
Brain
Localized enlargement of the abdominal aorta
aneurysms and to determine their size if present. Additionally, free peritoneal fluid can be detected. It is non-invasive and sensitive, but the presence of bowel
Abdominal_aortic_aneurysm
Method of analysis of genetic material
commonly used samples for metagenomic sequencing are blood, stool, cerebrospinal fluid (CSF), urine, or nasopharyngeal swabs. Among these, blood and CSF
Clinical metagenomic sequencing
Clinical_metagenomic_sequencing
Class of vitamins
is inconclusive, a lumbar puncture may be carried out to measure cerebrospinal fluid B12 levels. Serum haptocorrin binds 80-90% of circulating B12, rendering
Vitamin_B12
Chemical element with atomic number 53 (I)
tissues, including mammary glands, eyes, gastric mucosa, thymus, cerebrospinal fluid, choroid plexus, arteries, cervix, salivary glands. During pregnancy
Iodine
Medical condition
of metabolically inactive spaces e.g. cerebrospinal fluid in the case of gross hydrocephalus, which artificially lowers the calculated metabolism. Also
Disorder_of_consciousness
Movement disorder that causes involuntary tremors
Rommelspacher H (1996). "Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients". Journal of Neural Transmission. 103 (12):
Essential_tremor
Medical residency shifts done by interns
amyloid-beta, a protein aggregate commonly found in Alzheimer's, present in cerebrospinal fluid the following morning. Chronic sleep deprivation and the resulting
Medical_resident_work_hours
Injury due to pressure difference between gas filled space and adjoining tissue
round window. In the other, the tube remains closed and increased cerebrospinal fluid pressure is transmitted through the cochlea and causes outward rupture
Barotrauma
radioactive chemicals into malnourished babies and then collected cerebrospinal fluid for analysis from their brains and spines. In 1961 and 1962, ten
Unethical human experimentation in the United States
Unethical_human_experimentation_in_the_United_States
Monoamine neurotransmitter
males and females (measured by the concentration of 5-HIAA in the cerebrospinal fluid (CSF)). Dominance status and CSF serotonin levels appear to be positively
Serotonin
Canadian bioinformatician (born 1961)
quantitative metabolome analyses of human serum, urine, saliva, cerebrospinal fluid and feces. Wishart has made all his lab's data resources, computer
David_S._Wishart
Ability of a synapse to strengthen or weaken over time according to its activity
Pieter Jelle; Blennow, Kaj; Fladby, Tormod (13 October 2025). "Cerebrospinal fluid markers link to synaptic plasticity responses and Alzheimer's disease
Synaptic_plasticity
Blood infection caused by bacteria
of meningitis, a lumbar puncture can be attempted. If infected, cerebrospinal fluid (CSF) examination shows lymphocytic predominance with a cell count
Leptospirosis
Medical specialty dealing with disorders of the nervous system
perform lumbar punctures to assess characteristics of a patient's cerebrospinal fluid. Advances in genetic testing have made genetic testing an important
Neurology
cragged depression in its head containing water which acts as its cerebrospinal fluid. Korobokuru Common Korobokuru and Ishikorobokuru Dwarf-like race
List of Advanced Dungeons & Dragons 2nd edition monsters
List_of_Advanced_Dungeons_&_Dragons_2nd_edition_monsters
Species of lizard
ependymal cells that group around a tubular central canal containing cerebrospinal fluid. Axons are interspersed between these ependymal cells and encased
Lampropholis_delicata
Medical diagnostic method
brain. Subdural electrodes can shift slightly and can be affected by cerebrospinal fluid in the subdural space, which could interfere with the current used
Cortical_stimulation_mapping
American philanthropist, entrepreneur, inventor and futurist
therapy to address Alzheimer's disease by restoring the flow of cerebrospinal fluid across the cribriform plate in the nasal cavity. OncoSenX, a spinout
David_Gobel
chair over. The impact ruptured his dura mater, resulting in loss of cerebrospinal fluid. The injury was so painful that he has said he contemplated committing
List of film and television accidents
List_of_film_and_television_accidents
cyclosporin A CSA Controlled Substances Act C-section cesarean section CSF cerebrospinal fluid colony-stimulating factor CSME clinically significant macular edema
List of medical abbreviations: C
List_of_medical_abbreviations:_C
Discipline in biomedical engineering
Chih-Yang; Frim, David (2016). "Cerebrospinal Fluid Mechanics and Its Coupling to Cerebrovascular Dynamics". Annual Review of Fluid Mechanics. 48: 219–257. Bibcode:2016AnRFM
Neural_engineering
Hormone that inhibits hunger
can also impair leptin transport across the BBB. Studies on leptin cerebrospinal fluid (CSF) levels provide evidence for the reduction in leptin crossing
Leptin
Family of birds
relatively small and smooth brain, narrow subdural space, little cerebrospinal fluid surrounding it to prevent it from moving back and forth inside the
Woodpecker
Medical subspecialty
mater (which encloses the arachnoid mater, subarachnoid space, the cerebrospinal fluid, and the spinal cord). Injection of local anesthetics is often performed
Interventional_radiology
von Luschka, German anatomist – foramina of Luschka (outlets for cerebrospinal fluid in the brain); Luschka's crypts; Luschka's joints. Saint Lucy of
List_of_eponyms_(L–Z)
Chemical compound; chemotherapy medication
immediate intervention. Rescue treatments consist of washout of the cerebrospinal fluid and administration of protective medications. Children may do better
Vincristine
arteries to veins in capillaries. Cerebrospinal fluid: the physician Domenico Cotugno is credited with the discovery of this fluid in 1774. DDrna: a class of
List of Italian inventions and discoveries
List_of_Italian_inventions_and_discoveries
Electrophysiological method to record electrical activity of the brain
be used to make claims about global brain activity. The meninges, cerebrospinal fluid and skull "smear" the EEG signal, obscuring its intracranial source
Electroencephalography
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ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
ARTIFICIAL CEREBROSPINAL-FLUID
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