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Part of the innate immune system
C3b is the larger of two elements formed by the cleavage of complement component 3, and is considered an important part of the innate immune system. C3b
C3b
Aspect of the immune system
(C4b2b, historically referred C4b2a), which cleaves the C3 protein. The C3b component of the cleaved C3 binds to C3 convertase (C4b2b) to generate C5
Classical_complement_pathway
Type of cascade reaction of the complement system
pathways that opsonize and kill pathogens. The pathway is triggered when the C3b protein directly binds a microbe. It can also be triggered by foreign materials
Alternative complement pathway
Alternative_complement_pathway
Part of the immune system that enhances the ability of antibodies and phagocytic cells
the alternative pathway, C3b binds to Factor B. Factor D releases Factor Ba from Factor B bound to C3b. The complex of C3b(2)Bb is a protease which cleaves
Complement_system
American Aircraft
needed] Although there were several versions of the C3, most were either the C3B and the C3R. A few C3s were approved for float operations. The C3 was built
Stearman_C3
Type of immune system molecule
innate opsonization include C4b, C3b and iC3b. In the alternative pathway of complement activation, circulating C3b is deposited directly onto antigens
Opsonin
Class of serine proteases
C3b inactivator in the alternative pathway. C3b has different binding site for C3bINA, β1H, factor B and properdin. Binding β1H to C3b increases C3bINA
C3-convertase
Spanish anti-tank blast mines
The Expal C-3-A and C-3-B are round Spanish rubber modified polystyrene cased anti-tank blast mines. The mines differ only in minor detail. The mine is
C-3-A/B_mine
Formula One racing car
frequently failed to pre-qualify for races during 1989. It was updated to the C3B for the 1990 season, with the Cosworth DFR being replaced by a Subaru 1235
Coloni_C3
Protein found in humans
Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the
Complement_receptor_1
Protein found in humans
is cleaved by C3bBb, another form of C3-convertase composed of activated forms of C3 (C3b) and factor B (Bb). Once C3 is activated to C3b, it exposes a
Complement_component_3
glycine-rich beta-glycoprotein, heat-labile factor, C3 convertase, C3b,Bb,CVF,Bb,C5 convertase, (C3b)n,Bb, complement C 3(C 5) convertase (amplification), alternative
Alternative-complement-pathway C3/C5 convertase
Alternative-complement-pathway_C3/C5_convertase
Protein part of the complement system
factor I cleaves C3b. Complement receptors on white blood cells are able to bind iC3b, so iC3b functions as an opsonin. Unlike intact C3b, iC3b cannot associate
IC3b
Serine protease that plays key role in innate immunity
convertase differ in their C3b requirement. C3-convertase (C3bBb) need only one molecule of C3b to form, whereas two or more C3b are required for generation
C5-convertase
bacteria. CR3 also recognizes iC3b when bound to the surface of foreign cells. iC3b is generated by proteolysis of C3b and binding to the receptor causes
Macrophage-1_antigen
Protein found in humans
gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 on their surfaces, allowing
Complement_receptor_2
Mammalian protein found in Homo sapiens
regulates the complement system on the cell surface. It recognizes C4b and C3b fragments that are created during activation of C4 (classical or lectin pathway)
Decay-accelerating_factor
Reciprocating internal combustion engine
which had been used the previous season, was extensively modified into the "C3B" specification to be suitable for use with the Subaru 1235, and Bertrand
Subaru_1235
Protein found in humans
(from the N-terminus of the protein); CCPs 1–4 and CCPs 19–20 engage with C3b while CCPs 7 and CCPs 19–20 bind to GAGs and sialic acid. To date atomic
Factor_H
proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR)
C3a_(complement)
Protein
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein
Complement_factor_I
Physical effects resulting from activation of the immune system
Phagocytic efficacy can be enhanced by opsonization. Plasma derived complement C3b and antibodies that exude into the inflamed tissue during the vascular phase
Inflammation
Mammalian protein found in Homo sapiens
(ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties
Integrin_alpha_X
Protein family
phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces. complement system immunoglobulin
Complement receptor of the immunoglobulin family
Complement_receptor_of_the_immunoglobulin_family
Planned suburban rail line in Bengaluru, India
construction of line in two segments C3A and C3B, with C3A running from Kengeri to Bangalore Cantonment railway station and C3B from Cantonment to Whitefield, while
Parijaata_line
Protein-coding gene in the species Homo sapiens
up-regulator, stabilizing the C3bBb complex, and factor H is the down-regulator, promoting proteolytic degradation of C3b. Factor H is primarily produced
Properdin
Protein
complement factor I, which is an enzyme responsible for cleaving C3b into its inactive form, iC3b. When factor I is recruited to the bacterial surface through
Clumping_factor_A
Protein family
cell typesa Major activities CR1 Complement receptor 1 190,000–250,000 C3b, C4b, iC3b CD35 B, E, FDC, Mac, M0, PMN Immune complex transport (E); phagocytosis
Complement_receptor
Genetics on the peopling of the Americas
original migration into the Americas. Membership in haplogroups Q-M242 and C3b implies Indigenous American patrilineal descent. The micro-satellite diversity
Genetic history of the Indigenous peoples of the Americas
Genetic_history_of_the_Indigenous_peoples_of_the_Americas
cascade begins to work from C1 to C3b through C4b, C3b being further transformed to iC3b (inactive derivative of C3b), all of which, C4b and thereafter
Immune_adherence
Protein complex involved in the complement system
ability to bind C3b. C4BP accelerates decay of C3-convertase and is a cofactor for serine protease factor I which cleaves C4b and C3b. C4BP binds apoptotic
C4b-binding_protein
Chemical compound
is facilitated by C3b opsonization. Iptacopan acts proximally in the alternative pathway of the complement cascade to control both C3b-mediated extravascular
Iptacopan
(CD46) Decay Accelerating Factor, DAF (CD55) Protectin (CD59) Complement C3b/C4b Receptor 1, CR1 (CD35) Complement Regulator of the Immunoglobulin Superfamily
Complement_control_protein
Medical condition
bacteria are bound by IgG antibodies (IgG1 or IgG3) or the complement component C3b. These types of antibodies and complement are immune substances called opsonizers
Overwhelming post-splenectomy infection
Overwhelming_post-splenectomy_infection
Molecule formed binding antigens to antibodies
proteases. Red blood cells carrying CR1-receptors on their surface may bind C3b-coated immune complexes and transport them to phagocytes, mostly in liver
Immune_complex
Mongol ethnic group in Siberia, Mongolia, and Inner Mongolia
C-RPS4Y711/M130, including 117/217 (53.9%) C3d-M407, 18/217 (8.3%) C3∗-M217(xC3a-M93, C3b-P39, C3c-M77, C3d-M407, C3e-P53.1, C3f-P62), and 13/217 (6.0%) C3c-M77. Fourteen
Buryats
Protein domain
virus receptor or EBV-R) is the receptor for EBV and for C3d, C3dg and iC3b. Complement components may activate B cells through CD21. CD21 is part of
Sushi_domain
Buddhist site in Gansu, China
Republic of China C3 Cave 4 Sui Tang, (date unclear), Republic of China C3b Cave 5 Early Tang (date unclear) C4 Cave 7 Northern Wei Western Wei, Qing
Western_Thousand_Buddha_Caves
Human Y chromosome DNA grouping found primarily in Asia
C3a C3a C3a C3a C3a C3a C3a C3a C3a C3a C3a1 C-M208 10 V 1F 17 Eu6 H1 C C3b C2b C2a C2a C2b C2b C2a C2a C2a C2a C2a C-M210 36 V 1F 17 Eu6 H1 C C3c C2c
Haplogroup_C-M130
Cell membrane engulfing a large particle
oxidative burst in neutrophils. These receptors recognise targets coated in C3b, C4b and C3bi from plasma complement. The extracellular domain of the receptors
Phagocytosis
Excess number of eosinophil cells in the blood
Beliveau C, Baigent G, Gump D (1987). "Eosinophils of human colonic mucosa: C3b and Fc gamma receptor expression and phagocytic capabilities". Clinical Immunology
Eosinophilia
Human monocytic cell line
leukemia. Some of their characteristics are: Expression of Fc receptor and C3b receptors while lacking surface and cytoplasmic immunoglobulins. Production
THP-1_cell_line
Nematode
Microfilariae block this pathway by cleaving C3b—an important protein in this process—to form iC3b. iC3b cannot go on to activate the next step in the
Onchocerca_volvulus
Signal to activate immune cells
directly and complement component C3b bind to microbes. After C3b is degraded into a fragment iC3b (inactive derivative of C3b), then cleaved to C3dg, and finally
Co-stimulation
Mammalian protein found in Homo sapiens
system due to its capacity to bind inactivated complement component 3b (iC3b). The ITGAM (alpha) subunit of integrin αMβ2 is directly involved in causing
Integrin_alpha_M
Vertebrate cell
They bear membrane receptors for opsonins, such as IgG and the fragment C3b of complement. They express LCAs (leucocyte common antigens) CD45, CD14,
Histiocyte
Standard for developing and describing enterprise architectures
Capability Team (ACaT) of the NATO Consultation, Command and Control Board (C3B) in January 2018, provides guidance on describing both enterprise architectures
NATO_Architecture_Framework
Mixed use development in Bangkok, Thailand
Billion Buildings O4H4 (Signature Tower), O3, O2, O1B, O1AH1, H3C3A, C5, C3B, P5, H2A, H2B, R1, R2, R3, R4 Size 16.64 hectares Leasable area 1.83 million
One_Bangkok
American manufacturing company
of directors. In June 1928, the C2B airframe designation was changed to C3B, with a larger baggage compartment and oil tank. The factory was producing
Stearman_Aircraft
Protein-coding gene in the species Homo sapiens
protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. GRCh38:
V-set and immunoglobulin domain containing 4
V-set_and_immunoglobulin_domain_containing_4
Series of nine cylinder air-cooled radial aircraft engines
Ryan B-1 Brougham Spirit of St. Louis Stearman NS-1 Stearman C2B Stearman C3B Stinson Detroiter SB-1 and SM-1 Stinson Junior SM-2AB Swallow New Swallow
Wright_R-790_Whirlwind
Document issued by the United States Citizenship and Immigration Services
Office C3A F-1 Nonimmigrant, Pre-Completion Optional Practical Training C3B F-1 Nonimmigrant, Post-Completion Optional Practical Training C3C F-1 Nonimmigrant
Employment authorization document
Employment_authorization_document
Military-run national youth program
system that lays them out as uniforms C1, C2, C5, etc. Uniforms C1A, C3A, C3B, C5, and C5A are issued upon joining, along with Winter Accoutrements. Order
Royal_Canadian_Sea_Cadets
Air warfare branch of the Mexican Army
OU-2M Corsair with the 400 hp Wasp engine, nine Douglas O-2M, four Stearman C3B and six Waco Taper Wings. Only two weeks after making the request, the U
Mexican_Air_Force
Species of bacterium that can cause meningitis
acquisition. Porins are also recognized by TLR2, they bind complement factors (C3b, C4b, factor H, and C4bp (complement factor 4b-binding protein)). Cooperation
Neisseria_meningitidis
Airline of the United States (1930–2001)
DC-9-51 12 1993 Former Eastern Air Lines fleet. Northrop Alpha 14 1931 1935 Sikorsky S-61L 1 Unknown Unknown Helicopter Stearman C3B 1 Unknown Unknown
Trans_World_Airlines
Molecular markers associated with apoptosis
7 These include collectins, components of complement pathways (e.g. C1q, C3b) and other molecules found in extracellular space. Collectins (e.g. mannose-binding
ACAMPs
Motor car race
Coloni brought in ex-Rial and Onyx driver Bertrand Gachot to drive the C3B with its new Subaru-badged engine, while the sole Osella FA1M was to be driven
1990_United_States_Grand_Prix
Human Y-chromosome DNA haplogroup
Ya-Jun; Jin, Li; Li, Hui (2017). "Phylogeny of Y-chromosome haplogroup C3b-F1756, an important paternal lineage in Altaic-speaking populations". Journal
Haplogroup_C-M217
Type of white blood cell
(CR1) and 3 (CR3) that recognize pathogen-bound complement proteins C3b and iC3b, respectively, as well as fragment crystallizable γ receptors (FcγRs)
Macrophage
Family of cell surface receptors
known as the C3 convertase. C3 is cleaved into its a and b subunits, and C3b binds the convertase. These together are called the C5 convertase. Similarly
Pattern_recognition_receptor
Aviation museum in Blaine, Minnesota
Interstate S-1A Cadet Kreutzer K-5 Air Coach Paramount Cabinaire Stearman C3B Stearman Model 6 Cloudboy Stinson SM-6000-A Airliner Stinson SM-6000-B Airliner
Golden_Wings_Flying_Museum
Racing driver (born 1962)
Rial ARC2 Ford DFR 3.5 V8 JPN DNQ AUS DNQ 1990 Subaru Coloni Racing Coloni C3B Subaru 1235 F12 USA DNPQ BRA DNPQ SMR DNPQ MON DNPQ CAN DNPQ MEX DNPQ FRA
Bertrand_Gachot
Immunity strategy in living beings
into C3a and C3b. C3a aids in promoting opsonization and increases inflammation by helping immune cells move to the infection site, whereas C3b helps in forming
Innate_immune_system
Aviation museum
Alaska Aviation Museum. Retrieved June 2, 2018. "Airframe Dossier - Stearman C3B, c/n 121, c/r N5415". Aerial Visuals. AerialVisuals.ca. Retrieved June 3
Alaska_Aviation_Museum
Protein-coding gene in humans
factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin". FEBS Lett. 462 (3): 345–52. doi:10
CFHR3
Blood disorder in which cold sensitive antibodies target red blood cells
In lieu of the membrane attack complex, complement proteins (particularly C3b and C4b) are deposited on red blood cells. This opsonization enhances the
Cold_agglutinin_disease
1920's American Aircraft
the first certified Stearman aircraft, some C2 aircraft were modified to C3B standard. The most numerous version was the C2B which had a Wright J-5 radial
Stearman_C2
British protein biochemist, immunologist, and academic
antagonists of the AMD-associated variant of factor H (H384)". "C3b inactivating polypeptide". "C3b binding polypeptide". "Inhibitory nucleic acids for factor
Simon_J._Clark
Turkish admiral (born 1965)
key NATO executive boards, including Consultation Command Control Board (C3B), Agency Supervisory Board (ASB), Cyber Defense Management Board (CDMB),
Mustafa_Zeki_Uğurlu
RNA family
inhibitor and forms a tripartite complex with host complement Factor H and C3b". PLOS Pathog. 4 (12) e1000250. doi:10.1371/journal.ppat.1000250. PMC 2602735
SprD
Class of enzymes
must first bind with C3b before to form the C3bB complex. It is proposed that this conformational change of Factor B in the C3bB complex allows Factor
Factor_D
Blood infection caused by bacteria
down extracellular matrix, degrades fibrin clots and complemental proteins (C3b and C5) to avoid opsonisation. It can also recruit complement regulators
Leptospirosis
Airline of Mexico (1921–2010)
Model 9 Orion 3 1934 1946 Lockheed Model 10 Electra 8 1934 1938 Stearman C3B 3 Unknown Unknown Standard J1 8 1921 Unknown Travel Air 6000 4 1928 Unknown
Mexicana de Aviación (1921–2010)
Mexicana_de_Aviación_(1921–2010)
Indian reserve in Manitoba, Canada
announces plans for new Long Plain First Nation Wellness & Education Centre". C3b.264.myftpupload.com. 10 August 2020. Retrieved 11 November 2021. "Census
Long_Plain_First_Nation
Boeing 80 3 Fokker Super Universal (C6769, C7048, NC330M, NC7242) 2 Stearman C3B (C4686) List of defunct airlines of the United States "National Parks Airways
National_Parks_Airways
274.250.250 – complement c3a MeSH D12.776.124.486.274.250.260 – complement c3b MeSH D12.776.124.486.274.250.260.500 – complement c3c MeSH D12.776.124.486
List of MeSH codes (D12.776.124)
List_of_MeSH_codes_(D12.776.124)
System) Anti-personnel mines FMK1 (mine) No. 4 P4B SB33 Anti-tank mines C3B FMK3 M1 No. 6 SB81 Argentine Army: 194 (16 officers, 35 NCOs and 143 conscripts)
Falklands War order of battle: Argentine ground forces
Falklands_War_order_of_battle:_Argentine_ground_forces
Blood disorder in which antibodies target red blood cells
complex (MAC) or can bind the antibody, aiding phagocytosis by macrophages (C3b). This is one type of "penicillin allergy".[citation needed] In about half
Autoimmune_hemolytic_anemia
include Mfge8, Gas6, Protein S, antibodies and complement factors C1q and C3b. Phagoptosis has multiple functions including removal and disposal of: pathogenic
Phagoptosis
SpeB degrades immunoglobulins and cytokines, as well as through cleavage of C3b, inhibiting recruitment of phagocytic cells and the complement activation
Streptococcal pyrogenic exotoxin
Streptococcal_pyrogenic_exotoxin
North American subsidiary of Pantech
manufactures Slate, “world’s thinnest phone with a QWERTY keyboard,” and C3b, “the world’s smallest camera flip-phone.” Additionally, PWI created the
Pantech_Wireless
Medical condition
formation of a C3-convertase, which will cleave C3 molecules into C3a and C3b fragments. This is important because an unregulated C3-convertase will cause
Complement_3_deficiency
Species of bacterium
activation of complement protein 3 (C3). A cleaved portion of this protein, C3b, is deposited on pathogenic surfaces and results in opsonization as well
Neisseria_gonorrhoeae
Tendency of material in contact with blood to produce a clot
component C3 becomes permanently attached and turns into the reactive fragment C3b. The simultaneous release of bradykinin, clotting factors, and chemotactic
Thrombogenicity
Protein-coding gene in the species Homo sapiens
subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation
Complement_factor_B
Regulating the use of radio frequencies to promote efficient use
3 (CaP3), on behalf of the NATO Consultation, Command and Control Board (C3B), with participation of competent, authorised and mandated representatives
Spectrum_management
Family of gastropods
Austropeplea viridis Lymnaea sp. from Hawaii and from China Radix, n=17, C3b Radix labiata Radix peregra Radix ampla Radix lagotis Radix auricularia Radix
Lymnaeidae
1935 film directed by Noel M. Smith
Kinner SportsterK c/n 150, NC14237 Cycloplane C-1 c/n 3, NC12202 Stearman C3B c/n 235, NC8820 Travel Air 2000 c/n 322, NC3948 Alexander EaglerockA1 c/n
The_Fighting_Pilot
44th season of FIA Formula One motor racing
All 30 Aguri Suzuki All Subaru Coloni Racing Coloni Racing Subaru Coloni C3B Subaru 1235 3.5 F12 G 31 Bertrand Gachot 1–8 Coloni-Ford C3C Ford Cosworth
1990 Formula One World Championship
1990_Formula_One_World_Championship
Cross-referencing different names for Human Y chromosome DNA groupings
C3a C3a C3a C3a C3a C3a C3a C3a C3a C3a C3a1 C2a C-M208 10 V 1F 17 H1 C C3b C2b C2a C2a C2b C2b C2a C2a C2a C2a C2a C1b2a C-M210 36 V 1F 17 H1 C C3c
Conversion table for Y chromosome haplogroups
Conversion_table_for_Y_chromosome_haplogroups
Medical condition
conformational change that leads to C3 convertase breaking C3 into C3a and C3b. C3a, C5a, IL-8 are all chemotactic factors of the activated complement system
Diffuse proliferative nephritis
Diffuse_proliferative_nephritis
Chemical compound
structure and function of erythrocytes, in particular RBC-complement 3b (C3b) receptors. Animal studies on oral exposure of DMP in rats have established
Dimethyl_phthalate
Mammalian protein found in Homo sapiens
binding heat shock protein binding amyloid-beta binding complement component C3b binding integrin binding signaling receptor activity cargo receptor activity
Integrin_beta_2
Advanced and Challenge Convention maintained a C3B list until it disbanded in 2000. At the present, the C3B list is informally maintained by consensus of
Square_dance_program
Extracellular metalloprotease expressed by S. aureus
The active site has a high affinity for C3 and will cleave it into C3a and C3b however, the protein is cleaved two amino acid residues away from the native
Aureolysin
1933 American film
NC631H Travel Air 16K c/n 16K-2001, NR446W Standard J-1 Curtiss JN-4 Stearman C3B Emsco B7-C c/n 1, NC969-Y Travel Air R Mystery Ship, R-2002, NR613K Wedell-Williams
The_Phantom_of_the_Air
Aviation museum in Springfield, Illinois
Mustang "Worry Bird" Ryan PT-22 Recruit Sopwith Camel – replica Stearman C3B Stinson SM-2AA Junior Taylorcraft L-2M Grasshopper Vought F4U-5N Corsair
Air_Combat_Museum
1939 film directed by Christy Cabanne
July 26, 1939. The aircraft used in Legion of Lost Flyers was: Stearman C3B Fleet 1 c/n 374, NC792V Fokker F.10 Travel Air 2000 NC446W Frank Nugent in
Legion_of_Lost_Flyers
Mammalian protein found in humans
cofactor activity for inactivation (through cleavage) of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement
Membrane_cofactor_protein
C3B
C3B
C3B
C3B
Surname or Lastname
English
English : unexplained.Nicholas Wyeth emigrated from Suffolk, England to Cambridge, MA, before 1645. John Wyeth (1770–1858) was born in Cambridge and became a prominent publisher and editor in Harrisburg, PA.
Girl/Female
Muslim
Elegance
Surname or Lastname
English
English : habitational name from a place in Norfolk named Beccles, from Old English bec(e), bæce ‘stream’ + lǣs ‘meadow’.
Boy/Male
Indian, Sanskrit
First Light of Dawn
Boy/Male
Indian, Sanskrit
With a Waterjar; Lord Shiva
Boy/Male
Hindu
Victor, Eldest daughter or a Nakshatra
Surname or Lastname
English
English : variant of Harlin.German : possibly from a Germanic personal name derived from Old High German aro ‘eagle’.
Girl/Female
Indian
Eye, Thus precious
Girl/Female
Latin
Wife of Picus.
Female
Japanese
(çž³) Japanese name HITOMI means "pupil (of the eye)." This name is usually given to girls with especially beautiful eyes.Â
C3B
C3B
C3B
C3B
C3B