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CD28

  • CD28
  • Mammalian protein found in humans

    CD28 (cluster of differentiation 28) is a protein expressed on T cells that provides essential co-stimulatory signals required for T cell activation and

    CD28

    CD28

    CD28

  • Theralizumab
  • Monoclonal antibody

    Theralizumab (also known as TGN1412, CD28-SuperMAB, and TAB08) is an immunomodulatory drug developed by immunologist Thomas Hünig [de] of the University

    Theralizumab

    Theralizumab

  • CD28 family receptor
  • Group of regulatory cell surface receptors

    CD28 family receptors are a group of regulatory cell surface receptors expressed on immune cells. The CD28 family in turn is a subgroup of the immunoglobulin

    CD28 family receptor

    CD28 family receptor

    CD28_family_receptor

  • CD80
  • Mammalian protein found in humans

    works in tandem. Both CD80 and CD86 interact with costimulatory receptors CD28, CTLA-4 (CD152) and the p75 neurotrophin receptor. CD80 is a member of the

    CD80

    CD80

    CD80

  • CAR T cell
  • Genetically engineered T cell

    significant remissions. In the early 2000s, co-stimulatory domains such as CD28 or 4-1BB were added to first generation CAR's CD3ζ intracellular domain.

    CAR T cell

    CAR_T_cell

  • Acazicolcept
  • Pharmaceutical compound

    Acazicolcept (ALPN-101) is an experimental dual CD28/ICOS antagonist developed by AbbVie. It appears to be a peptide with 363 residues. Yang, Jing; Lickliter

    Acazicolcept

    Acazicolcept

  • B7 (protein)
  • Integral membrane protein

    activated antigen-presenting cells (APC) that, when paired with either a CD28 or CD152 (CTLA-4) surface protein on a T cell, can produce a costimulatory

    B7 (protein)

    B7_(protein)

  • Cytotoxic T-lymphocyte associated protein 4
  • Mammalian protein found in humans

    and avidity than CD28 thus enabling it to outcompete CD28 for its ligands. CTLA-4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory

    Cytotoxic T-lymphocyte associated protein 4

    Cytotoxic T-lymphocyte associated protein 4

    Cytotoxic_T-lymphocyte_associated_protein_4

  • Co-stimulation
  • Signal to activate immune cells

    receptor is genetically closely related to CD28 but cannot substitute for its function. Among many similarities with CD28, it also induces Akt activity through

    Co-stimulation

    Co-stimulation

  • Ipilimumab
  • Pharmaceutical drug

    CTLA-4 in mice, its conservation in humans and similarities with CD28 were soon noticed. CD28 at that time was a recently identified "T cell costimulatory"

    Ipilimumab

    Ipilimumab

    Ipilimumab

  • VEL-101
  • formerly FR104, is an experimental monovalent, pegylated fab' antibody against CD28. It is developed for transplant rejection and autoimmune diseases. Ville

    VEL-101

    VEL-101

  • ICOS (gene)
  • Protein found in humans

    the ICOS (Inducible T-cell COStimulator) gene. The protein belongs to the CD28 and CTLA-4 cell-surface receptor family. These are proteins expressed on

    ICOS (gene)

    ICOS (gene)

    ICOS_(gene)

  • TNFRSF4
  • Protein-coding gene in humans

    receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed

    TNFRSF4

    TNFRSF4

    TNFRSF4

  • T cell
  • White blood cells of the immune system

    simultaneous engagement of the T-cell receptor and a co-stimulatory molecule (like CD28, or ICOS) on the T cell by the major histocompatibility complex (MHCII) peptide

    T cell

    T cell

    T_cell

  • CD86
  • Mammalian protein found in humans

    molecule CD28 on the surface of all naïve T cells, and to the inhibitory receptor CTLA-4 (cytotoxic T-lymphocyte antigen-4, also known as CD152). CD28 and

    CD86

    CD86

    CD86

  • Antigen-presenting cell
  • Cell that displays antigen bound by MHC proteins on its surface

    for T cell activation, including CD40 and B7. The latter can interact with CD28 on the surface of a CD4+ T cell. The dendritic cell is then a fully mature

    Antigen-presenting cell

    Antigen-presenting cell

    Antigen-presenting_cell

  • Programmed cell death protein 1
  • Mammalian protein found in humans

    I membrane protein of 288 amino acids. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. The protein's structure includes an extracellular

    Programmed cell death protein 1

    Programmed cell death protein 1

    Programmed_cell_death_protein_1

  • Fc receptor
  • Surface protein important to the immune system

    successfully substitute the CD28 requirement during autoimmunity. In an autoimmune background CD4+ T cells bypass the requirement of CD28 cosignaling to become

    Fc receptor

    Fc receptor

    Fc_receptor

  • Immune checkpoint
  • Regulators of the immune system

    Another two stimulatory checkpoint molecules belong to the B7-CD28 superfamily—CD28 itself and ICOS. CD27: This molecule supports antigen-specific expansion

    Immune checkpoint

    Immune checkpoint

    Immune_checkpoint

  • T helper cell
  • Type of immune cell

    interaction between CD28 on the CD4+ T cell and the proteins CD80 (B7.1) or CD86 (B7.2) on the professional APCs. Both CD80 and CD86 activate the CD28 receptor.

    T helper cell

    T helper cell

    T_helper_cell

  • BTLA
  • Protein-coding gene in the species Homo sapiens

    cluster of differentiation 272 or CD272) is a protein that belongs to the CD28 immunoglobulin superfamily (IgSF) which is encoded by the BTLA gene located

    BTLA

    BTLA

    BTLA

  • Superantigen
  • Antigen which strongly activates the immune system

    up to 20% of the body's T-cells. Furthermore, Anti-CD3 and Anti-CD28 antibodies (CD28-SuperMAB) have also shown to be highly potent superantigens (and

    Superantigen

    Superantigen

    Superantigen

  • Immunosenescence
  • Immune system deterioration brought on by aging

    antigen-recognition repertoire of T-cell receptor (TcR) diversity down-regulation of CD28 costimulatory molecules cytotoxic activity of Natural Killer T cells (NKTs)

    Immunosenescence

    Immunosenescence

    Immunosenescence

  • Reactive arthritis
  • Inflammatory arthritis triggered by infection elsewhere in the body

    Quest. Somoza, C.; Lanier, L.L. (February 1995). "T-cell costimulation via CD28-CD80/CD86 and CD40-CD40 ligand interactions". Research in Immunology. 146

    Reactive arthritis

    Reactive arthritis

    Reactive_arthritis

  • Interleukin 2
  • Mammalian protein found in humans

    pathways: NFAT, NFkB and AP-1. In addition and after costimulation from CD28 the optimal activation of expression of IL-2 and these pathways is induced

    Interleukin 2

    Interleukin 2

    Interleukin_2

  • Kinetic-segregation model of T cell activation
  • Model for the mechanism of T-cell receptor triggering

    receptors of the Non-catalytic tyrosine-phosphorylated receptors family such as CD28. On plasma membrane of a T cell there is the T-cell receptor (consists of

    Kinetic-segregation model of T cell activation

    Kinetic-segregation_model_of_T_cell_activation

  • Avery August
  • Belizean-born American scientist (born 1964)

    the molecular basis for T cell co-stimulation by the cell surface protein CD28. This work resulted in 9 publications (see references at PubMed). This work

    Avery August

    Avery August

    Avery_August

  • TNFRSF9
  • Protein found in humans

    antibody secretion. As a T cell co-stimulator, T cell receptor (TCR) and CD28 signaling causes expression of CD137 on T cell membranes. When CD137 then

    TNFRSF9

    TNFRSF9

    TNFRSF9

  • Interleukin 10
  • Anti-inflammatory cytokine

    "A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase

    Interleukin 10

    Interleukin 10

    Interleukin_10

  • Craig B. Thompson
  • American cell biologist and cancer researcher

    of CD28 in augmenting lymphoid effector function, proliferation, and survival. Thompson identified the evolutionary duplication of CD28 into CD28 and

    Craig B. Thompson

    Craig B. Thompson

    Craig_B._Thompson

  • Rheumatoid arthritis
  • Type of autoimmune arthritis

    loci include genes affecting co-stimulatory immune pathways—for example CD28 and CD40, cytokine signaling, lymphocyte receptor activation threshold (e

    Rheumatoid arthritis

    Rheumatoid arthritis

    Rheumatoid_arthritis

  • List of minor planets: 364001–365000
  • 6, 2007 Mount Lemmon Mount Lemmon Survey  · 2.5 km MPC · JPL 364467 2007 CD28 — January 27, 2007 Kitt Peak Spacewatch  · 1.8 km MPC · JPL 364468 2007 CS28

    List of minor planets: 364001–365000

    List_of_minor_planets:_364001–365000

  • P-selectin glycoprotein ligand-1
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    P-selectin glycoprotein ligand-1

    P-selectin glycoprotein ligand-1

    P-selectin_glycoprotein_ligand-1

  • Abatacept
  • Immunomodulating pharmaceutical drug

    the APC must present a B7 protein (CD80 or CD86) on its cell surface to a CD28 protein on the surface of the T cell. These two signals activate the T cell

    Abatacept

    Abatacept

  • Endothelial protein C receptor
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Endothelial protein C receptor

    Endothelial protein C receptor

    Endothelial_protein_C_receptor

  • CD22
  • Lectin molecule

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD22

    CD22

    CD22

  • CD20
  • Mammalian protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD20

    CD20

    CD20

  • CD3G
  • Protein-coding gene in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD3G

    CD3G

    CD3G

  • RHCE (gene)
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    RHCE (gene)

    RHCE (gene)

    RHCE_(gene)

  • CD300A
  • Human gene

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD300A

    CD300A

    CD300A

  • OX40 ligand
  • Protein family

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    OX40 ligand

    OX40_ligand

  • Compugen Ltd.
  • Israeli biotechnology company

    Evogene, established as an agriscience division in 1999. PVRIG is a novel B7/CD28-like immune checkpoint target candidate. In June 2016, Compugen announced

    Compugen Ltd.

    Compugen_Ltd.

  • Glycophorin C
  • Protein family

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Glycophorin C

    Glycophorin_C

  • Toll-like receptor 3
  • Protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Toll-like receptor 3

    Toll-like receptor 3

    Toll-like_receptor_3

  • Immunological synapse
  • Interface between lymphocyte and target cell

    (central-SMAC) composed of the θ isoform of protein kinase C, CD2, CD4, CD8, CD28, Lck, and Fyn. p-SMAC (peripheral-SMAC) within which the lymphocyte function-associated

    Immunological synapse

    Immunological synapse

    Immunological_synapse

  • CNPY2
  • CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CNPY2

    CNPY2

    CNPY2

  • MSR1
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    MSR1

    MSR1

    MSR1

  • CD8A
  • Protein-coding gene in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD8A

    CD8A

    CD8A

  • Cytokine-induced killer cell
  • cytokine-induced killer cells with chimeric antigen receptors: CD28 outperforms combined CD28-OX40 "super-stimulation"". Molecular Therapy. 21 (12): 2268–77

    Cytokine-induced killer cell

    Cytokine-induced_killer_cell

  • VE-cadherin
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    VE-cadherin

    VE-cadherin

    VE-cadherin

  • Cadherin-2
  • Protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Cadherin-2

    Cadherin-2

    Cadherin-2

  • CLEC10A
  • Protein-coding gene in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CLEC10A

    CLEC10A

    CLEC10A

  • ICOSLG
  • Protein-coding gene in the species Homo sapiens

    B7 family due to the significant homology with B7 family members. The B7/CD28 superfamily provides both positive and negative co-signals to immunocytes

    ICOSLG

    ICOSLG

    ICOSLG

  • Basigin
  • Mammalian protein found in Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Basigin

    Basigin

    Basigin

  • P110δ
  • Protein-coding gene in the species Homo sapiens

    subsets. In T cells, the antigen receptor (TCR) and costimulatory receptors (CD28 and ICOS) are thought to be main receptors responsible for recruiting and

    P110δ

    P110δ

    P110δ

  • Lymphocyte-activation gene 3
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Lymphocyte-activation gene 3

    Lymphocyte-activation gene 3

    Lymphocyte-activation_gene_3

  • Carbohydrate
  • Organic compound that consists only of carbon, hydrogen, and oxygen

    Ma BY, Mikolajczak SA, Yoshida T, Yoshida R, Kelvin DJ, Ochi A (2004). "CD28 T cell costimulatory receptor function is negatively regulated by N-linked

    Carbohydrate

    Carbohydrate

    Carbohydrate

  • T memory stem cell
  • both naïve T cells markers, such as CD45RA+, CD45RO-, high levels of CD27, CD28, IL-7Rα (CD127), CD62L, and C-C chemokine receptor 7 (CCR7), as well as markers

    T memory stem cell

    T_memory_stem_cell

  • Interleukin-4 receptor
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Interleukin-4 receptor

    Interleukin-4 receptor

    Interleukin-4_receptor

  • FCGR2B
  • Antibody fragment receptor in humoral immunity

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    FCGR2B

    FCGR2B

    FCGR2B

  • Integrin alpha E
  • Protein-coding gene in the species Homo sapiens

    Tilburgs T, Scherjon SA, Roelen DL, Claas FH (February 2009). "Decidual CD8+CD28- T cells express CD103 but not perforin". Human Immunology. 70 (2): 96–100

    Integrin alpha E

    Integrin alpha E

    Integrin_alpha_E

  • Single-chain variable fragment
  • Fragment

    recombinant antibody fragments derived from antibodies that block the CD80/CD86-CD28 costimulatory pathway". Protein Expression and Purification. 22 (1): 11–24

    Single-chain variable fragment

    Single-chain variable fragment

    Single-chain_variable_fragment

  • Long-lived plasma cell
  • White blood cell

    high-affinity antibodies. CD28: Signaling through the Vav/Grb2 motif can induce NF-κB signaling and expression of BLIMP-1. CD28 engagement with its ligands

    Long-lived plasma cell

    Long-lived_plasma_cell

  • Integrin alpha 5
  • Protein

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Integrin alpha 5

    Integrin alpha 5

    Integrin_alpha_5

  • CARD11
  • Protein-coding gene in humans

    Wang D, Matsumoto R, You Y, Che T, Lin XY, Gaffen SL, et al. (2004). "CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of

    CARD11

    CARD11

    CARD11

  • List of minor planets: 28001–29000
  • CQ27 — February 10, 1999 Socorro LINEAR EOS 6.6 km MPC · JPL 28279 1999 CD28 — February 10, 1999 Socorro LINEAR  · 15 km MPC · JPL 28280 1999 CG28 — February

    List of minor planets: 28001–29000

    List_of_minor_planets:_28001–29000

  • Cluster of differentiation
  • Classification in immunology

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Cluster of differentiation

    Cluster_of_differentiation

  • List of modern Hangul characters in ISO/IEC 2022–compliant national character set standards
  • ᄎ+ᅩ+ᆼ 촤 U+CD24 35-50 — 30-70 45-49 ᄎ+ᅪ+∅ 촥 U+CD25 — 32-09 30-71 — ᄎ+ᅪ+ᆨ 촨 U+CD28 35-51 — 30-72 45-50 ᄎ+ᅪ+ᆫ 촫 U+CD2B — 32-10 — — ᄎ+ᅪ+ᆮ 촬 U+CD2C 35-52 — 30-73

    List of modern Hangul characters in ISO/IEC 2022–compliant national character set standards

    List_of_modern_Hangul_characters_in_ISO/IEC_2022–compliant_national_character_set_standards

  • Gamma-glutamyltransferase 1
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Gamma-glutamyltransferase 1

    Gamma-glutamyltransferase 1

    Gamma-glutamyltransferase_1

  • Memory T cell
  • Subset of T lymphocytes

    cells, TSCM cells are CD45RO−, CCR7+, CD45RA+, CD62L+ (L-selectin), CD27+, CD28+, and IL-7Rα+, but they also express large amounts of CD95, IL-2Rβ, CXCR3

    Memory T cell

    Memory_T_cell

  • CD36
  • Mammalian protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD36

    CD36

    CD36

  • Michel Sadelain
  • American immunologist

    Latouche, JB; Tan, C; Cheung, NK; Sadelain, M (1998). "Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically

    Michel Sadelain

    Michel Sadelain

    Michel_Sadelain

  • Carl H. June
  • American immunologist and oncologist

    T-cell therapy for cancer. In the 1980s, his lab supported research for the CD28 molecule as the major control switch for T cells. A few years later, his

    Carl H. June

    Carl H. June

    Carl_H._June

  • CD44
  • Cell-surface glycoprotein

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD44

    CD44

    CD44

  • Centroblast
  • Enlarged B cell in the germinal center of lymphoid follicles

    in the lymphoid follicle and is produced by centroblasts interacting with CD28+ helper T cells. The production of the germinal center is important for the

    Centroblast

    Centroblast

    Centroblast

  • CD68
  • Mammalian protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD68

    CD68

    CD68

  • Null cell
  • Lymphocytes without surface receptors

    Cytomegalovirus (CMV) has been shown to induce T-lymphocytes to stop expressing CD28 and other critical surface molecules. This alteration essentially converts

    Null cell

    Null cell

    Null_cell

  • CD276
  • Protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CD276

    CD276

    CD276

  • Cytotoxic T cell
  • T cell that kills infected, damaged or cancerous cells

    coreceptor and the class I MHC molecule to stabilize this signal. Second Signal CD28 molecule on the T cell either CD80 or CD86 (also called B7-1 and B7-2) CD80

    Cytotoxic T cell

    Cytotoxic T cell

    Cytotoxic_T_cell

  • GB 12052
  • Korean-language character set in China

    CDFB 췽 CDFD 츼 CE3C 츽 CE3D 칀 CE40 칄 CE44 칏 CE4F 4D5x/CDDx 칑 CE51 촤 CD24 촨 CD28 촹 CD39 춷 CDB7 쵀 CD40 췡 CDE1 췠 CDE0 칻 CE7B 캇 CE87 캍 CE8D 캰 CEB0 켝 CF1D 켣 CF23

    GB 12052

    GB_12052

  • Cereblon E3 ligase modulator
  • Class of immunomodulatory drugs

    with the co-stimulation of T-cells through the B7-CD28 complex by phosphorylating tyrosine on the CD28 receptor. In vitro data suggests this co-stimulation

    Cereblon E3 ligase modulator

    Cereblon E3 ligase modulator

    Cereblon_E3_ligase_modulator

  • P-glycoprotein
  • Protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    P-glycoprotein

    P-glycoprotein

    P-glycoprotein

  • MAP3K11
  • Protein-coding gene in humans

    Scheidereit C, Dröge W, Schmitz ML (2000). "Mixed-Lineage Kinase 3 Delivers CD3/CD28-Derived Signals into the IκB Kinase Complex". Mol. Cell. Biol. 20 (7): 2556–68

    MAP3K11

    MAP3K11

    MAP3K11

  • C5a receptor
  • Mammalian protein found in Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    C5a receptor

    C5a receptor

    C5a_receptor

  • CLEC9A
  • Protein-coding gene in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    CLEC9A

    CLEC9A

    CLEC9A

  • FCAR
  • Mammalian protein found in Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    FCAR

    FCAR

    FCAR

  • Stichodactyla toxin
  • Protein family

    memory T cells that are CD28+ are refractory to suppression by Kv1.3 blockers when they are co-stimulated by anti-CD3 and anti-CD28 antibodies, but are sensitive

    Stichodactyla toxin

    Stichodactyla toxin

    Stichodactyla_toxin

  • Joel N. Blankson
  • American medical academic

    (1): 57–62. PMC 1384024. PMID 7635522. Blankson, J.; Morse, S. (1994). "The CD28/B7 pathway costimulates the response of primary murine T cells to superantigens

    Joel N. Blankson

    Joel_N._Blankson

  • Lulizumab pegol
  • Monoclonal antibody

    Lulizumab pegol Monoclonal antibody Type ? Source Humanized Target glycoprotein CD28 Clinical data Other names BMS-931699 ATC code none Identifiers CAS Number

    Lulizumab pegol

    Lulizumab_pegol

  • Hashimoto's thyroiditis
  • Autoimmune disease

    Greenberg DA, Barbesino G, Concepcion E, Davies TF (April 2001). "CTLA-4 and not CD28 is a susceptibility gene for thyroid autoantibody production". The Journal

    Hashimoto's thyroiditis

    Hashimoto's thyroiditis

    Hashimoto's_thyroiditis

  • PROM1
  • Protein found in humans

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    PROM1

    PROM1

    PROM1

  • Plasma cell leukemia
  • Medical condition

    multiple myeloma patients; and pPCL plasma cells more frequently express CD28 than do sPCL plasma cells. Thus, immunophenotyping supports that notion that

    Plasma cell leukemia

    Plasma cell leukemia

    Plasma_cell_leukemia

  • Single-domain antibody
  • Antibody fragment

    Li D, Pan J, Ren H, Hoeltzel G, et al. (April 2023). "The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal

    Single-domain antibody

    Single-domain antibody

    Single-domain_antibody

  • Priming (immunology)
  • First contact antigen-specific T helper cell precursors have with an antigen

    includes a B7 ligand complex on antigen-presenting cells binding to the CD28 receptor on T cells); and cytokines that control differentiation into different

    Priming (immunology)

    Priming_(immunology)

  • List of minor planets: 100001–101000
  • — February 3, 1997 Kitt Peak Spacewatch  · 2.4 km MPC · JPL 100536 1997 CD28 — February 6, 1997 Xinglong SCAP (5) 2.8 km MPC · JPL 100537 1997 EL4 — March

    List of minor planets: 100001–101000

    List_of_minor_planets:_100001–101000

  • NKG2
  • Mammalian protein found in Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    NKG2

    NKG2

  • Sialyl-Lewis X
  • Chemical compound

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Sialyl-Lewis X

    Sialyl-Lewis X

    Sialyl-Lewis_X

  • Integrin alpha D
  • Protein-coding gene in the species Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    Integrin alpha D

    Integrin alpha D

    Integrin_alpha_D

  • B-cell activating factor
  • Mammalian protein found in Homo sapiens

    CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42

    B-cell activating factor

    B-cell activating factor

    B-cell_activating_factor

  • Immunosuppressive drug
  • Drug that inhibits activity of immune system

    transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling". BMC Immunology. 13 (1) 12. doi:10.1186/1471-2172-13-12

    Immunosuppressive drug

    Immunosuppressive drug

    Immunosuppressive_drug

AI & ChatGPT searchs for online references containing CD28

CD28

AI search references containing CD28

CD28

AI search queries for Facebook and twitter posts, hashtags with CD28

CD28

Follow users with usernames @CD28 or posting hashtags containing #CD28

CD28

Online names & meanings

  • Gita
  • Boy/Male

    Hindu, Indian, Telugu

    Gita

    Holy Book

  • En-tappuah
  • Biblical

    En-tappuah

    fountain of an apple, or of inflation

  • Manu
  • Boy/Male

    Egyptian Hindi

    Manu

    Born second.

  • Iftikharllah
  • Boy/Male

    Arabic, Islamic, Muslim, Pakistani, Urdu

    Iftikharllah

    Glory / Pride of Allah

  • Anna
  • Biblical

    Anna

    gracious; one who gives

  • Mawby
  • Surname or Lastname

    English

    Mawby

    English : habitational name from Mautby in Norfolk. Compare Maultsby.

  • Dilbaag
  • Boy/Male

    Sikh

    Dilbaag

    Heart blossom

  • Sanidh
  • Boy/Male

    Hindu

    Sanidh

  • Janis
  • Girl/Female

    Hebrew American English

    Janis

    Gift from God.

  • Edmund
  • Boy/Male

    American, Anglo, British, Christian, Danish, English, Finnish, French, German, Irish, Polish, Shakespearean, Swedish

    Edmund

    Wealthy Defender; Prosperous Protection; Rich Protector; Protector of Prosperity

AI search & ChatGPT queries for Facebook and twitter users, user names, hashtags with CD28

CD28

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CD28

AI searchs for Acronyms & meanings containing CD28

CD28

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Other words and meanings similar to

CD28

AI search in online dictionary sources & meanings containing CD28

CD28