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White blood cells of the immune system
of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate
T_cell
Medical condition
T cell deficiency is a deficiency of T cells, caused by decreased function of individual T cells, it causes an immunodeficiency of cell-mediated immunity
T_cell_deficiency
Type of immune cell
The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune
T_helper_cell
Genetically engineered T cell
Chimeric antigen receptor T cells (CAR T cells)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor
CAR_T_cell
T cell that kills infected, damaged or cancerous cells
A killer T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or cd8) is a T lymphocyte (a type of white
Cytotoxic_T_cell
Hematologic cancer that affects lymphocytes
diseases of lymphoid cells (i.e., B cells, T cells, NK cells, and histiocytic-dendritic cells) in which one or more of these cell types is infected with
Lymphoma
Cancerous overproduction of T cells
T-cell lymphoma is a rare form of cancerous lymphoma affecting T-cells. Lymphoma arises mainly from the uncontrolled proliferation of lymphocytes, such
T-cell_lymphoma
White blood cells of the immune system
The regulatory T cells (Tregs /ˈtiːrɛɡ/ or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune
Regulatory_T_cell
Protein complex on the surface of T cells that recognizes antigens
The T-cell receptor (TCR) is a protein complex, located on the surface of T cells (also called T lymphocytes). They are responsible for recognizing fragments
T-cell_receptor
Class of artificial monoclonal antibodies
T-cell engager (TCE) or Bi-specific T-cell engager (BiTE) is a class of artificial bispecific monoclonal antibodies that are investigated for use as anti-cancer
T_cell_engager
Subtype of white blood cell
cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for
Lymphocyte
Type of cancer
high numbers of abnormal blood cells. These blood cells are not fully developed and are called blasts or leukemia cells. Signs and symptoms may include
Leukemia
Subset of pro-inflammatory T helper cells
T helper 17 cells (Th17) are a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17). They are related to T
T_helper_17_cell
T cells with some properties of natural killer cells
T and natural killer cells. Natural killer T cells are a distinct type of cells and should not be confused as natural killer cells or killer T cells (cytotoxic
Natural_killer_T_cell
T cell subset
Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed
Gamma_delta_T_cell
A T-cell vaccine is a vaccine designed to induce protective T-cells. It is not a vaccine whereby T-cells are administered to the patient. T-cell vaccines
T-cell_vaccine
Subset of T lymphocytes
Memory T cells are a subset of T lymphocytes that might have some of the same functions as memory B cells. Their lineage is unclear. Antigen-specific memory
Memory_T_cell
Species of virus
Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus (HTLV-I or HTLV-1), also called the adult T-cell lymphoma virus type 1, is a retrovirus
Human_T-lymphotropic_virus_1
T cell which has not yet encountered its cognate antigen
In immunology, a naive T cell (Th0 cell) is a T cell that has differentiated in the thymus, and successfully undergone the positive and negative processes
Naive_T_cell
Biological system protecting an organism against disease
antibody-producing B cells. Gamma delta T cells (γδ T cells) possess an alternative T-cell receptor (TCR) as opposed to CD4+ and CD8+ (αβ) T cells and share the
Immune_system
Group of disorders
or more types of lymphoid cells (a type of white blood cell), i.e. B cells, T cells, NK cells, and histiocytic-dendritic cells, are infected with the Epstein–Barr
Epstein–Barr virus–associated lymphoproliferative diseases
Epstein–Barr_virus–associated_lymphoproliferative_diseases
Cell that displays antigen bound by MHC proteins on its surface
presentation. T cells may recognize these complexes using their T cell receptors (TCRs). APCs process antigens and present them to T cells. Almost all cell types
Antigen-presenting_cell
Type of cytotoxic lymphocyte
lymphoid cells (ILC), and represent 5–20% of all circulating lymphocytes in humans. The role of NK cells is analogous to that of cytotoxic T cells in the
Natural_killer_cell
Type of immune system cancer
non-Hodgkin lymphomas (which are generally B-cell-related), CTCL is caused by a mutation of T cells. The cancerous T cells in the body initially migrate to the
Cutaneous_T-cell_lymphoma
Type of cancer immunotherapy
T cell receptor T cell therapy (TCR-T) is a type of adoptive T-cell therapy that targets some cancers. TCR-T therapies are based on the use and redirection
T cell receptor T cell therapy
T_cell_receptor_T_cell_therapy
Type of white blood cell
believed. B cells, unlike the other two classes of lymphocytes, T cells and natural killer cells, express B cell receptors (BCRs) on their cell membrane
B_cell
Type of acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia characterized by an aggressive malignant neoplasm of the bone marrow
T-cell acute lymphoblastic leukemia
T-cell_acute_lymphoblastic_leukemia
Medical condition
T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver
T-cell prolymphocytic leukemia
T-cell_prolymphocytic_leukemia
Medical condition
two main categories: T-cell LGL leukemia (T-LGLL) and natural-killer (NK)-cell LGL leukemia (NK-LGLL). As the name suggests, T-cell large granular lymphocyte
Large granular lymphocytic leukemia
Large_granular_lymphocytic_leukemia
Immune response that does not involve antibodies
cells or T helper cells (also known as helper T cells) provide protection against distinct pathogens. Naive T cells, which are immature T cells that have
Cell-mediated_immunity
Activation or suppression of the immune system to treat disease
approaches: (1) TIL therapy, (2) T cell receptor-engineered T cells (TCR-T cells), and (3) chimeric antigen receptor T cells (CAR-T cells), with newer adaptations
Immunotherapy
Skin disease
drug or its metabolite stimulates cytotoxic T cells (i.e. CD8+ T cells) and T helper cells (i.e. CD4+ T cells) to initiate autoimmune reactions that attack
Stevens–Johnson_syndrome
Human retrovirus, cause of AIDS
HIV infects vital cells in the human immune system, such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads
HIV
Artificial stimulation of the immune system to treat cancer
enhance T cell activity against tumors. These therapies have shown effectiveness in treating cancers such as melanoma and lung cancer. Adoptive cell therapies
Cancer_immunotherapy
Medical condition
leukemia Adult T-cell leukemia/lymphoma T-cell prolymphocytic leukemia In practice, it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and
T-cell_leukemia
Accessory cell of the mammalian immune system
on the cell surface to the T cells of the immune system. They act as messengers between the innate and adaptive immune systems. Dendritic cells are present
Dendritic_cell
Immunization with inactivated T-cells
T-cell vaccination is immunization with inactivated autoreactive T cells. The concept of T-cell vaccination is, at least partially, analogous to classical
T-cell_vaccination
Group of rare lymphomas
Mature T-cell lymphoma, also called peripheral T-cell lymphoma, is a group of rare, aggressive lymphomas that develop from mature white blood cells and originate
Mature_T-cell_lymphoma
Medical condition
Angioimmunoblastic T-cell lymphoma (AITL, sometimes misspelled AILT, formerly known as "angioimmunoblastic lymphadenopathy with dysproteinemia") is a mature T-cell lymphoma
Angioimmunoblastic T-cell lymphoma
Angioimmunoblastic_T-cell_lymphoma
Type of cells of the immunological system
Lymphoid cells (lymphocytes) include T cells (subdivided into helper T cells, memory T cells, cytotoxic T cells), B cells (subdivided into plasma cells and
White_blood_cell
Medical condition
Hepatosplenic T-cell lymphoma is a rare form of lymphoma that is generally incurable, except in the case of an allogeneic stem cell transplant. It is
Hepatosplenic_T-cell_lymphoma
Type of blood cancer
center B-cell within the mantle zone that surrounds normal germinal center follicles. MCL cells generally over-express cyclin D1 due to the t(11:14) translocation
Mantle_cell_lymphoma
Cancer of plasma cells
myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies
Multiple_myeloma
Human disease
Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare cancer of the immune system's T-cells caused by human T cell leukemia/lymphotropic virus type 1
Adult T-cell leukemia/lymphoma
Adult_T-cell_leukemia/lymphoma
Bone marrow cancer in which lymphocytes are overproduced
type of white blood cell. B cell lymphocytes can begin to collect in the blood, spleen, lymph nodes, and bone marrow; these cells malfunction and crowd
Chronic_lymphocytic_leukemia
Medical condition
Cutaneous T-cell lymphomas Angioimmunoblastic T-cell lymphoma Extranodal natural killer/T-cell lymphoma, nasal type Enteropathy type T-cell lymphoma Subcutaneous
Peripheral_T-cell_lymphoma
Informal grouping of virus species
T-lymphotropic viruses (STLVs). PTLVs are named for their ability to cause adult T-cell leukemia/lymphoma, but in the case of HTLV-1 it can also cause a demyelinating
Primate_T-lymphotropic_virus
Immune cell
thymocyte is an immune cell present in the thymus, before it undergoes transformation into a T cell. Thymocytes are produced as stem cells in the bone marrow
Thymocyte
Blood cancer characterized by overproduction of lymphoblasts
lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes
Acute_lymphoblastic_leukemia
A T memory stem cell (TSCM) is a type of long-lived memory T cell with the ability to reconstitute the full diversity of memory and effector T cell subpopulations
T_memory_stem_cell
Medical condition
emphasis on cell lineage. To this end, lymphoid leukemias can also be divided by the type of cells affected: B-cell leukemia T-cell leukemia NK-cell leukemia
Lymphoid_leukemia
Removal of autoreactive T and B cells outside of the primary lymphoid organs
bone marrow (after T and B cells egress from primary lymphoid organs). Its main purpose is to ensure that self-reactive T and B cells which escaped central
Peripheral_tolerance
Mammalian protein found in humans
is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating
Programmed cell death protein 1
Programmed_cell_death_protein_1
Endocrine gland
primary lymphoid organ of the immune system. Within the thymus, T cells mature. T cells are critical to the adaptive immune system, where the body adapts
Thymus
Cell line
Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of
Jurkat_cells
Protein-coding gene in the species Homo sapiens
regulator' of hematopoietic stem cells, and plays a critical role in the development of plasma B cells, T cells, dendritic cells (DCs), macrophages, and osteoclasts
PRDM1
Japanese manga series by Akane Shimizu
when necessary. She went through T Cell training alongside Killer T Cell and Helper T Cell. Naive T Cell (ナイーブT細胞, Naību T Saibō) Voiced by: Mutsumi Tamura
Cells_at_Work!
The list of human cell types provides an enumeration and description of the various specialized cells found within the human body, highlighting their
List_of_human_cell_types
Immunotherapy using T cells
Cellular adoptive immunotherapy is a type of immunotherapy. Immune cells such as T cells are usually isolated from patients for expansion or engineering
Cellular adoptive immunotherapy
Cellular_adoptive_immunotherapy
Lymphocyte T-cell immunomodulator (LTCI) is an immune regulating polypeptide, which is a potent regulator of CD-4 lymphocyte production and function. It
Lymphocyte T-cell immunomodulator
Lymphocyte_T-cell_immunomodulator
Mammalian protein found in humans
CD4+ T cells and activated CD8+ T cells. Put shortly, the function of IL-2 is to stimulate the growth of helper, cytotoxic and regulatory T cells. IL-2
Interleukin_2
(DCs) are antigen presenting cells for the induction of antigen specific T cell response. DC-based immunotherapy is safe and can promote antitumor immune
Dendritic cell-based cancer vaccine
Dendritic_cell-based_cancer_vaccine
Type of blood cancer
Diffuse large B-cell lymphoma (DLBCL) is a cancer of B cells, a type of lymphocyte that is responsible for producing antibodies. It is the most common
Diffuse_large_B-cell_lymphoma
Subsystem of the immune system
vaccination. The cells that carry out the adaptive immune response are white blood cells known as lymphocytes. B cells and T cells, two different types
Adaptive_immune_system
Type of immune cell involved in germinal center formation and maintenance
T cells (also known as T follicular helper cells and abbreviated as TFH), are antigen-experienced CD4+ T cells found in the periphery within B cell follicles
Follicular_B_helper_T_cells
Medical condition
including T-cell acute lymphoblastic leukemia. Types of T-cell acute lymphoblastic leukemia include adult T-cell leukemia/lymphoma and (precursor) T-lymphoblastic
Acute_leukemia
Medical diagnostic method
cytometry procedure that uses tetrameric proteins to detect and quantify T cells that are specific for a given antigen within a sample (e.g. blood, CSF)
Tetramer_assay
T-cell depletion (TCD) is the process of T cell removal or reduction, which alters the immune system and its responses. Depletion can occur naturally
T-cell_depletion
Type of cancer
distinct from anaplastic large cell lymphoma, a T-cell lymphoma. Upregulation of ALK is mainly due to chromosomal translocation t(2;17), resulting in a fusion
ALK+_large_B-cell_lymphoma
Antigen which strongly activates the immune system
system. Specifically they cause non-specific activation of T-cells resulting in polyclonal T cell activation and massive cytokine release. Superantigens act
Superantigen
Immunomodulating pharmaceutical drug
In order for a T cell to be activated and produce an immune response, an antigen-presenting cell must present two signals to the T cell. One of those signals
Abatacept
Signal to activate immune cells
signal which immune cells rely on to activate an immune response in the presence of an antigen-presenting cell. In the case of T cells, two stimuli are required
Co-stimulation
Excessive production of lymphocytes by the immune system
Acute lymphoblastic leukemia Hairy cell leukemia Hemophagocytic lymphohistiocytosis (HLH) B-cell lymphomas T-cell lymphomas Multiple myeloma Waldenström's
Lymphoproliferative_disorders
Chemical entity which can be bound by an antibody
is recognized by the immune system, specifically by antibodies, B cells, or T cells. The part of an antibody that binds to the epitope is called a paratope
Epitope
Spectrum of conditions caused by HIV infection
spread and cell-to-cell spread, i.e. it employs hybrid spreading mechanisms. In the cell-free spread, virus particles bud from an infected T cell, enter the
HIV/AIDS
T helper 3 cells (Th3) are a subset of T lymphocytes with immunoregulary and immunosuppressive functions, that can be induced by administration of foreign
T_helper_3_cell
Tumors that affect the blood, bone marrow, lymph, and lymphatic system
erythrocytes, thrombocytes, macrophages and mast cells; the lymphoid cell line produces B, T, NK and plasma cells. Lymphomas, lymphocytic leukemias, and myeloma
Tumors of the hematopoietic and lymphoid tissues
Tumors_of_the_hematopoietic_and_lymphoid_tissues
Human protein and gene for T-cell signaling
The Linker for activation of T cells, also known as linker of activated T cells or LAT, is a protein involved in the T-cell antigen receptor signal transduction
Linker for activation of T cells
Linker_for_activation_of_T_cells
Elimination of autoreactive lymphocytes by the immune system
central tolerance is necessary because T cell receptors (TCRs) and B cell receptors (BCRs) are made by cells through random somatic rearrangement. This
Central_tolerance
Complication of celiac disease
Enteropathy-associated T-cell lymphoma (EATL), previously termed enteropathy-associated T-cell lymphoma, type I and at one time termed enteropathy-type T-cell lymphoma
Enteropathy-associated T-cell lymphoma
Enteropathy-associated_T-cell_lymphoma
Tissue-resident memory T cells or TRM cells represent a subset of a long-lived memory T cells that occupies epithelial, mucosal and other tissues (skin
Tissue-resident_memory_T_cell
Adaptive immunity variety-generation process
T and B cell maturation. It results in the highly diverse repertoire of antibodies/immunoglobulins and T cell receptors (TCRs) found in B cells and T
V(D)J_recombination
American biotechnology company
genetically engineered autologous CAR T cell therapy - a cell-based therapy which relies on chimeric antigen receptors and T cells. Founded in 2009, and based in
Kite_Pharma
Hematological malignancy
Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. The incidence of hairy cell leukemia
Hairy_cell_leukemia
Blood cancer that affects B-type white blood cells
The B-cell lymphomas are types of lymphoma affecting B cells. Lymphomas are "blood cancers" in the lymph nodes. They develop more frequently in older adults
B-cell_lymphoma
Protein-coding gene in the species Homo sapiens
types of cell, or cells at different developmental stages. Most immune cells (or leukocytes) secrete TGF-β1. Some T cells (e.g. regulatory T cells) release
TGF_beta_1
Immune system deterioration brought on by aging
rates of morbidity and mortality in older adults. Along with anergy and T-cell exhaustion, immunosenescence is among the major dysfunctional states of
Immunosenescence
Human disease caused by protist parasites
receptors on B cells increased Leishmania antigen-specific T cell proliferation and IFN-γ secretion. Co-culture of T cells with B cells decreased the percentage
Visceral_leishmaniasis
Autoimmune disease of skin and muscle
Novel approaches such as CD19 chimeric antigen receptor (CAR) T-cell therapy, plasma cell–directed therapies, and neonatal Fc receptor (FcRn) inhibitors
Dermatomyositis
Virtual memory T cells (TVM) are a subtype of T lymphocytes. These are cells that have a memory phenotype but have not been exposed to a foreign antigen
Virtual_memory_T_cell
Cellular process
antigen-presenting cells (mostly dendritic cells) to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells).
Cross-presentation
InterPro Family
in cells such as macrophages, B cells, and CD8+ cytotoxic T cells, it is able to promote inflammation, antiviral or antibacterial activity, and cell proliferation
Interferon_gamma
Mammalian protein found in humans
protein expressed on T cells that provides essential co-stimulatory signals required for T cell activation and survival. When T cells are stimulated through
CD28
Medical condition
Extranodal NK/T-cell lymphoma, nasal type (ENKTCL-NT) (also termed angiocentric lymphoma, nasal-type NK lymphoma, NK/T-cell lymphoma, polymorphic/malignant
Extranodal NK/T-cell lymphoma, nasal type
Extranodal_NK/T-cell_lymphoma,_nasal_type
Part of the variable chains in immunoglobulins and T cell receptors
variable chains in immunoglobulins (antibodies) and T cell receptors, generated by B-cells and T-cells respectively. CDRs are where these molecules bind
Complementarity-determining region
Complementarity-determining_region
Protein found in humans
of T cells called T follicular helper cells (TFH cells). On TFH cells, CD154 promotes B cell maturation and function by engaging CD40 on the B cell surface
CD154
Monoclonal antibody
involved in recognising antigens and activating T cells) on the surface of T-cells and modifying T-cell immune behaviour to reduce cytotoxicity. This appears
Teplizumab
Rare type of lymphoma
of cutaneous T-cell lymphoma that was first described by Albert Sézary. The affected T cells, known as Sézary's cells or Lutzner cells, have pathological
Sézary_disease
Protein-coding gene in the species Homo sapiens
by NK cells, NK1.1+ T cells, γδ T cells, activated CD8+ αβ T cells and activated macrophages. In humans, it is expressed by NK cells, γδ T cells and CD8+
NKG2D
Autoimmune diseases of the skin
of CD4+ helper T cells and Th17 helper T cells. The diminished CD4+ T cell presence is thought to cause overactivation of CD8+ T cells, which are responsible
Psoriasis
T CELL
T CELL
Male
Czechoslovakian
, given.
Female
Egyptian
, the daughter of Osirtesen.
Female
Egyptian
, a sister of the prince Ra-hotep.
Male
Hungarian
Hungarian form of Old High German Bernhard, BERNÃT means "bold as a bear."
Male
Hungarian
Czech and Hungarian form of Latin Donatus, DONÃT means "given (by God)."
Female
Icelandic
Icelandic form of Latin Margarita, MARGRÉT means "pearl."
Female
Egyptian
, the goddess of darkness.
Female
Egyptian
, the wife of Toti.
Surname or Lastname
English, French, German, Hungarian (Donát), Polish, and Czech (Donát)
English, French, German, Hungarian (Donát), Polish, and Czech (Donát) : from a medieval personal name (Latin Donatus, past participle of donare, frequentative of dare ‘to give’). The name was much favored by early Christians, either because the birth of a child was seen as a gift from God, or else because the child was in turn dedicated to God. The name was borne by various early saints, among them a 6th-century hermit of Sisteron and a 7th-century bishop of Besançon, all of whom contributed to the popularity of the baptismal name in the Middle Ages, which was not checked by the heresy of a 4th-century Carthaginian bishop who also bore it. Another bearer was a 4th-century gramMarian and commentator on Virgil, widely respected in the Middle Ages as a figure of great learning.
Male
Czechoslovakian
, earnest, serious.
Female
Egyptian
, a daughter of Rameses II; & a wife of Rameses II.
Female
Egyptian
, The Most Powerful of Beings.
Female
Egyptian
, the name of several Egyptian ladies.
Female
Egyptian
, an Egyptian lady, the wife of Antefaker.
Female
Egyptian
, the mother of the priest Fai-iten-hemh-bai.
Female
Norse
Old Norse name composed of the elements bjarga "to rescue" and ljótr "bright, light," hence "rescue light."Â
Female
Egyptian
, the daughter of King Snefru.
Female
Egyptian
, The Good Companion.
Female
Egyptian
, the goddess of time.
Male
Czechoslovakian
, living.
T CELL
T CELL
Female
African
(the one who comes quickly) the first-born of twins.
Boy/Male
Indian, Sanskrit
Cows World
Girl/Female
Hindu, Indian, Tamil
Goddess Saraswathi
Male
Egyptian
, the son of Mizraim.
Boy/Male
Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Physical Bonding
Girl/Female
Tamil
Arpita | à®…à®°à¯à®ªà®¿à®¤à®¾
Dedicate, Presenting
Biblical
a heap of skulls; something skull-shaped
Girl/Female
Arabic, Australian, Danish, French, German, Hebrew, Polish, Swedish
Coming of Dawn; Form of Sarah; Princess; Shining; Flower; Radiance; Blossoming Flower; Day's Awakening
Girl/Female
Biblical
Defluxion, imposthume.
Girl/Female
Biblical
The gift or death of a striker.
T CELL
T CELL
T CELL
T CELL
T CELL
v. t.
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