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The chaperone code refers to post-translational modifications of molecular chaperones that control protein folding. Whilst the genetic code specifies
Chaperone_code
2018 film directed by Michael Engler
The Chaperone is a 2018 period drama film, directed by Michael Engler, with a screenplay by Julian Fellowes, from the novel by Laura Moriarty. It stars
The_Chaperone_(2018_film)
1998 musical
The Drowsy Chaperone is a Canadian musical with music and lyrics by Lisa Lambert and Greg Morrison, and a book by Bob Martin and Don McKellar. The story
The_Drowsy_Chaperone
1st episode of the 6th season of Seinfeld
"The Chaperone" is the first episode of the sixth season of the American television sitcom Seinfeld, and the 87th episode overall. It first aired on NBC
The_Chaperone_(Seinfeld)
British-American biochemist (born 1973)
(2020-08-07). "Post-translational modifications of Hsp90 and translating the chaperone code". The Journal of Biological Chemistry. 295 (32): 11099–11117. doi:10
Mehdi_Mollapour
Canadian scientist
methylation of molecular chaperones is a central element of a posttranslational modification code, they termed the "chaperone code", that orchestrates the
Benoit_Coulombe
Protein found in humans
BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy
BAG3
Protein-coding gene in the species Homo sapiens
functions as a co-chaperone which reversibly links together the chaperone proteins Hsp70 and Hsp90. STI1 belongs to the large group of co-chaperones, which regulate
Stress-induced-phosphoprotein 1
Stress-induced-phosphoprotein_1
Medication for transthyretin amyloidosis
drugs that rely on those transporters. Tafamidis is a pharmacological chaperone that stabilizes the correctly folded tetrameric form of the transthyretin
Tafamidis
Corticosteroid medication
Upon binding, the formation of the GC/GCR complex causes dissociation of chaperone proteins from the glucocorticoid receptor enabling the GC/GCR complex
Prednisolone
Chris's deal worked out. Ziggy runs into Fatty who asks her to consider chaperoning one of his young stars so she feigns sickness to be Fatty's assistant
List_of_Traders_episodes
Protein-coding gene in the species Homo sapiens
chromosome 11. As a member of the heat shock protein 70 family and a chaperone protein, it facilitates the proper folding of newly translated and misfolded
HSPA8
2nd episode of the 6th season of Seinfeld
Hallo as Gendason Lauren Bowles as Waitress Episode chronology ← Previous "The Chaperone" Next → "The Pledge Drive" Seinfeld season 6 List of episodes
The_Big_Salad
Family of proteins
wound healing or tissue remodeling. Many members of this group perform chaperone functions by stabilizing new proteins to ensure correct folding or by
Heat_shock_protein
Heat shock proteins with a molecular mass around 90kDa
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in
Hsp90
Chemical compound
Sodium phenylbutyrate is also a histone deacetylase inhibitor and chemical chaperone, leading respectively to research into its use as an anti-cancer agent
Sodium_phenylbutyrate
Protein-coding gene in the species Homo sapiens
functions as a co-chaperone which inhibits the ATPase activity of the chaperone Hsp90 (heat shock protein-90) and decelerates its chaperone cycle. FNIP1 acts
FNIP1
American actor
Meanie (2025) as The Chaperone Appofeniacs (2025) as Cedrick Night Patrol (2025) as Xavier Carr Faces of Death (2026) as Josh Guy Code (2012) as Himself
Jermaine_Fowler
American science fiction TV series
Karolina Wydra as Zosia, a Polish member of the Others who acts as Carol's chaperone Carlos-Manuel Vesga as Manousos Oviedo, a Colombian immune individual
Pluribus_(TV_series)
know what he's doing. Margaret tells Jim that they've been asked to be chaperones at the dance. Jim doesn't want Bud to be surprised when his parents are
List of Father Knows Best episodes
List_of_Father_Knows_Best_episodes
Corticosteroid medication
multiprotein complexes with heat shock proteins (HSPs), immunophilins, and other chaperones such as src, and p23. The GR acts in a ligand-dependent manner, with the
Methylprednisolone
Protein-coding gene in the species Homo sapiens
Mesoderm development LRP chaperone, or MESD, is a protein that in humans is encoded by the MESD gene. GRCh38: Ensembl release 89: ENSG00000117899 – Ensembl
Mesoderm development LRP chaperone
Mesoderm_development_LRP_chaperone
Protein family around which DNA winds to form nucleosomes
functional specialization within chaperone networks. Given their critical roles, misregulation of histone chaperones has been implicated in diseases such
Histone
Process of cells digesting parts of themselves
forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. In macroautophagy (the most
Autophagy
Free online crowdsourced encyclopedia
December 26, 2008. Wilson, Chris (February 22, 2008). "The Wisdom of the Chaperones". Slate. Archived from the original on September 5, 2011. Retrieved August
Wikipedia
1946 fire in Atlanta, Georgia
staying at the Winecoff. She suffocated with another delegate and their chaperone in room 926. Christine Adams Hinson (age 17), daughter of Isham Lamar
Winecoff_Hotel_fire
Chemical compound
on their binding properties to prion proteins: implications as medical chaperones". Protein Science. 22 (1): 22–34. doi:10.1002/pro.2180. PMC 3575857. PMID 23081827
Pentosan_polysulfate
22nd episode of the 5th season of Seinfeld
Player #3 Jeffrey von Meyer as Poker Player #4 Episode chronology ← Previous "The Hamptons" Next → "The Chaperone" Seinfeld season 5 List of episodes
The_Opposite
Chemical compound
and PARP-dependent energy crisis in human skin cells". Cell Stress & Chaperones. 15 (3): 309–322. doi:10.1007/s12192-009-0145-6. PMC 2866994. PMID 19809895
Zinc_pyrithione
Dad [de] Mark von Seydlitz [de] Julia Stinshoff, Lambert Hamel Comedy a.k.a. Chaperoned a.k.a. Urlaub mit Papa Der verlorene Sohn [de] Nina Grosse Katja Flint
List of German films of the 2000s
List_of_German_films_of_the_2000s
American comedy series
punishment for leaving his classes early for rehearsals, Kate forces Kel to chaperone the winter formal. He recruits Abby to help Beth, a snobby student who
Not_Suitable_for_Work
Protein-coding gene in humans
part of the small heat shock protein family and functions as molecular chaperone that primarily binds misfolded proteins to prevent protein aggregation
CRYAB
Phylum of microscopic animals
propose (2019) that this may serve "as a RNA-chaperone involved in regulation of translation [of RNA code to proteins] following freezing." Tardigrade
Tardigrade
the valley trying to get support for the festival. Meanwhile, Doris is chaperoning Arnold and his girlfriend Sue Ann. Lisa comes by to talk about the festival
List_of_Green_Acres_episodes
Protein-coding gene in the species Homo sapiens
that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly
Binding immunoglobulin protein
Binding_immunoglobulin_protein
American sitcom
lies to Leanne and Carol about going to the doctor's. Leanne decides to chaperone Daddy to all his doctor's appointments and coordinates all his appointments
Leanne_(TV_series)
which complete genome data are available. STGA belongs to a family of co-chaperone proteins that obtain a TPR motif. STGA was discovered just 15 years ago
SGTA
American and French actor (born 1995)
Holden, Stephen (September 15, 2016). "Review: In 'Miss Stevens,' a Chaperone Greets Temptation". The New York Times. Archived from the original on
Timothée_Chalamet
Hopewell Paul Rose 11 March 2015 (2015-03-11) N/A After Dexter agrees to chaperone Nero at Elmsmere's parents' evening and assigns the gang more homework
List of 4 O'Clock Club episodes
List_of_4_O'Clock_Club_episodes
British actor (born 1953)
(1991), Boogie Nights (1997), Chocolat (2000), Luther (2003), The Da Vinci Code (2006), and Love Is Strange (2014). He has voiced characters in Rango (2011)
Alfred_Molina
American actress
operative Liz "Foxfire" Towne, in the short-lived NBC action television series Code Name: Foxfire (1985). In 1982, Cassidy had her breakthrough film role as
Joanna_Cassidy
Protein-coding gene in the species Homo sapiens
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene. The oncogene BCL2 is a membrane protein that blocks
BAG1
Protein-coding gene in humans
Hsp90 co-chaperone Cdc37 is a protein that in humans is encoded by the CDC37 gene. This protein is highly similar to Cdc 37, a cell division cycle control
CDC37
Chemical compound
BPPSA (N‐(2‐bromophenyl)pyrrolidine‐1‐sulfonamide) is a small molecular chaperone that helps partially stabilize the P187S variant of NQO1, recovering part
BPPSA
Protein-coding gene in humans
Copper chaperone for superoxide dismutase is a metalloprotein that is responsible for the delivery of Cu to superoxide dismutase (SOD1). CCS is a 54kDa
CCS_(gene)
British television soap opera (1985–present)
spent on scripts and £6.9 million went towards paying actors, extras and chaperones for child actors. According to the NAO, BBC executives approved £500,000
EastEnders
English editor (1868–1905)
carriage with the elderly family cook Elizabeth Harper (or other servant as chaperone) or her fellow illustrator and friend Gertrude Woodward. Potter and Warne
Norman_Warne
knowing. Mary also tries to avoid being alone with Pastor Rob while chaperoning the event. George takes Principal Petersen out and runs into Brenda anyway
List of Young Sheldon episodes
List_of_Young_Sheldon_episodes
Protein-coding gene in the species Homo sapiens
GroEL is a protein which belongs to the chaperonin family of molecular chaperones, and is found in many bacteria. It is required for the proper folding
GroEL
Protein-coding gene in the species Homo sapiens
BAG family molecular chaperone regulator 4 is a protein that in humans is encoded by the BAG4 gene. The protein encoded by this gene is a member of the
BAG4
hosted by Cheryl. As Lori covers for Lynn Sr. and Rita into being Lola's chaperone due to both of them being unavailable, Lola worries about losing when
List of The Loud House episodes
List_of_The_Loud_House_episodes
Pharmaceutical compound
β-glucocerebrosidase (GCase) activator, positive allosteric modulator, and/or chaperone which is under development for the treatment of Parkinson's disease, Gaucher's
GT-02287
Muslim dating app
detailed profile creation, selfie verification, privacy settings, and a chaperone feature that allows a third party to monitor interactions. The app also
Muzz_(dating_app)
Wife of J. R. R. Tolkien (1889–1971)
University, "Father Francis sometimes came to visit from Birmingham, once chaperoning Edith. She remembered the train stopping at Banbury and Father Francis
Edith_Tolkien
2026 video game
they will need to go meet up with their half brother Jeppy who is being chaperoned by Creature (Tim Robinson), a gatlian from the first game. When we go
High_on_Life_2
Period drama television series
added to the cast. Simone Kirby joined the cast in October as the girls' chaperone. In December 2023, it was confirmed that the main ensemble would return
The Buccaneers (2023 TV series)
The_Buccaneers_(2023_TV_series)
American monster television series
to Japan under an alias after discovering that her company was using her code for nefarious purposes. Her real name is later revealed as Corah Mateo. Ren
Monarch:_Legacy_of_Monsters
Medication
strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase
Miglustat
not to be left in a room alone with him again. According to McDowell, a chaperone had accompanied her to Trump's office. At the time, McDowell was 21 and
Donald Trump sexual misconduct allegations
Donald_Trump_sexual_misconduct_allegations
1930 film by Al Christie
pose as Charley's Brazilian Aunt Donna Lucia. Their purpose is to have a chaperone for their amorous visits with Amy and Kitty, niece and ward of crusty
Charley's_Aunt_(1930_film)
Protein-coding gene in the species Homo sapiens
import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding
TOMM34
curmudgeonly history teacher at a New England prep school is forced to chaperone the handful of students with nowhere to go over Christmas break. Holidate
List_of_Christmas_films
does not spend much time with his mother, but one day she agrees to help chaperone a field trip with his class. He is thrilled by his mother's involvement
List_of_Mad_Men_characters
Topics referred to by the same term
Australian Multicultural Council U.S. Army Chemical Materials Activity Chaperone-mediated autophagy Calcium magnesium acetate, an inorganic compound
CMA
English actress
Kenvale Recruitment. Bettles was born in 1969 to a mother who worked as a chaperone for the Grange Hill series from its inception in 1978 to 2002. She and
Alison_Bettles
American actress (1905–1965)
left New York, her father, and her boyfriend behind for Hollywood. As chaperone for the journey and her subsequent southern California stay, the studio
Clara_Bow
American author, journalist, and social activist (1876–1916)
visit with her sister Tess and her chaperone, Miss Hadley. It hardly seems likely that someone who required a chaperone on Saturday would move aboard as
Jack_London
information center. Retrieved July 2, 2014. "Capital punishment in Guam" (PDF). Code of the Trust Territory of the Pacific Islands, 1980 Edition: 11 TTC § 751
List of death row inmates in the United States
List_of_death_row_inmates_in_the_United_States
Mexican-American actress (1956)
Episode (1.2) 1984 The Love Boat Samantha Gregory Episode " My Mother, My Chaperone/Present, The/Death and Life of Sir Alfred Demerest, The/Welcome Aboard:
Ana_Alicia
2025 American television series
positive compliment towards Phoebe's leadership book. Phoebe ropes Max into chaperoning the field trip. Later that night, Thunderford sends a text to the Thundermans
The_Thundermans:_Undercover
Protein-coding gene in the species Homo sapiens
Tubulin-specific chaperone D is a protein that in humans is encoded by the TBCD gene. Cofactor D is one of four proteins (cofactors A, D, E, and C) involved
TBCD
1920s women's subculture
Flock and the Royal Order of the Flapper. Flappers shrugged off their chaperones, danced suggestively, and openly flirted with boys. "Flappers prized style
Flapper
American series of parties hosted by Sean Combs
it in 2000, lent Combs the Declaration but hired three armed guards to chaperone it throughout the night. This marked "a new level of fortune and braggadocio"
Diddy_parties
Inherited neurodegenerative disorder
mHTT may cause cell death have been identified. These include effects on chaperone proteins, which help fold proteins and remove misfolded ones; interactions
Huntington's_disease
Mammalian protein involved in blood clotting
reference expression data BioGPS n/a Gene ontology Molecular function chaperone binding protein homodimerization activity collagen binding protein N-terminus
Von_Willebrand_factor
American actor (born 1991)
Year Title Role Notes 2016 The Layoff Jeremy Short film 2018 The Chaperone Floyd Spare Room Matt 2024 The Front Room Norman 2025 Snow White Jonathan TBD
Andrew_Burnap
Cystic fibrosis drug
destroy such proteins soon after they are made; lumacaftor acts as a chaperone during protein folding and increases the number of CFTR proteins that
Lumacaftor/ivacaftor
Pathogenic type of misfolded protein
In yeast, protein refolding to the prion configuration is assisted by chaperone proteins such as Hsp104. All known prions induce the formation of an amyloid
Prion
Indian actress (1933–1969)
pushed her into anything ... He couldn't imagine he'd get so caught up chaperoning her that he'd never get back to working himself." Madhubala was eventually
Madhubala
Major character on the TV show "Seinfeld"
personal assistant to the eccentric, demanding Justin Pitt, starting in "The Chaperone", but later is fired when Mr. Pitt thinks she and Jerry are conspiring
Elaine_Benes
American television sitcom
facilitate a camping field trip. Evan and Gwen are dogged by Sharon, a parent chaperone who is paranoid about the students playing sex games. Evan becomes jealous
English_Teacher_(TV_series)
Mitotic crossover Model organisms Modifier gene Molecular biology Molecular chaperone Molecular farming Molecular genetics Molecular imprinting Molecular medicine
Index_of_genetics_articles
they make themselves into teenagers named "Hillary" and "Zellery" to chaperone the trip. Problems arise when Gordie falls for Zellery, Hillary fights
List of Sabrina the Teenage Witch episodes
List_of_Sabrina_the_Teenage_Witch_episodes
Restorationist Christian denomination
religious sanctions. Dating Jehovah's Witnesses are encouraged to have a chaperone when they are together to avoid acting on sexual desires. All sexual relations
Jehovah's_Witnesses
German philosopher (1844–1900)
Tautenburg in Thuringia, often with Nietzsche's sister Elisabeth as a chaperone. Salomé reports that he asked her to marry him on three separate occasions
Friedrich_Nietzsche
Christian sect formerly known as the Exclusive Brethren
marriage and are encouraged to marry within the fellowship. Courtship is chaperoned, and physical intimacy before marriage is strongly discouraged. Elderly
Plymouth Brethren Christian Church
Plymouth_Brethren_Christian_Church
Attitudes and behaviors towards sex in ancient Rome
boy for sexual purposes, or to bribe the boy's chaperone (comes) for the opportunity. Negligent chaperones could be prosecuted under various laws, placing
Sexuality_in_ancient_Rome
Honduran actor (born 1965)
Short Twilight Mr. Molina 2010 Smell the Coffee Ricky Short 2011 The Chaperone Carlos 2012 Eye of the Hurricane Roberto Cruz The Forger Mr. Weathers
José_Zúñiga_(actor)
Chaperoned student group on foot
school bus) is a form of student transport for young schoolchildren who, chaperoned typically by two adults (a "driver" leads and a "conductor" follows),
Walking_bus
American supernatural horror television series
boys to continue their work on earth, assigning Night Nurse as their chaperone. Somewhere in the Arctic, the Sprites sit with an unknown figure holding
Dead Boy Detectives (TV series)
Dead_Boy_Detectives_(TV_series)
2019 Marvel Studios film
#CaptainMarvelChallenge, a campaign to purchase tickets and refreshments for girls and chaperones at the Greater Los Angeles chapter of Girls, Inc. The campaign, inspired
Captain_Marvel_(film)
American stage and film director (1903–1986)
with Universal Pictures and Georgette was assigned by their parents to chaperone her. At a Hollywood party, Vernon Duke introduced Minnelli to Georgette
Vincente_Minnelli
Protein-coding gene in the species Homo sapiens
protein 47, also known as SERPINH1, is a serpin which serves as a human chaperone protein for collagen. HSP47 contains 3 beta sheets and 9 alpha helices
Heat_shock_protein_47
Protein-coding gene in the species Homo sapiens
molecular chaperone. Chaperones are proteins that bind to other proteins, thereby stabilizing them in an ATP-dependent manner. Chaperones stabilize new
HSP90AB1
American comedian and writer
Socialists of America, has performed at DSA-LA fundraisers, and was a chaperone at the DSA-LA 2026 Prom. She was dropped from her representation in 2023
Jamie_Loftus
He trained under S. Theodora Markson, who was also Lemony Snicket's chaperone during his early training. Markson often describes Bertrand as a model
List of A Series of Unfortunate Events characters
List_of_A_Series_of_Unfortunate_Events_characters
Ethnic group of Louisiana, USA
transported to Louisiana. (The Ursuline order of nuns, who were said to chaperone the girls until they married, denied the casket girl myth.) The system
Louisiana_Creole_people
Storyboarded by : Aaron Springer; Sherm Cohen (director) 2515–115 12 12 "The Chaperone" Sean Dempsey Written by : Sherm Cohen, Aaron Springer & Peter Burns Storyboarded
List of SpongeBob SquarePants episodes (seasons 1–10)
List_of_SpongeBob_SquarePants_episodes_(seasons_1–10)
Role in social psychology defined as providing assistance in courtship
have been called wingmen in literature, film and popular culture. Bro Code Chaperone Sidekick DiDonato, Theresa E. (February 21, 2014). "The Evolution of
Wingman_(social)
American comedy-drama television series
in the house and yells at Max and her friends for leaving it out. Sam chaperones Frankie and her friends to a poetry slam event where they are performing;
Better_Things_(TV_series)
travel, tourism, insurance
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