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Mammalian protein found in humans
Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow
Granulocyte colony-stimulating factor
Granulocyte_colony-stimulating_factor
Family of proteins
Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of committed progenitors in the bone marrow
Colony-stimulating_factor
Mammalian protein found in Homo sapiens
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages
Granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage_colony-stimulating_factor
Mammalian protein found in humans
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem
Macrophage colony-stimulating factor
Macrophage_colony-stimulating_factor
Protein found in humans
The granulocyte colony-stimulating factor receptor (G-CSF-R) also known as CD114 (Cluster of Differentiation 114) is a protein that in humans is encoded
Granulocyte colony-stimulating factor receptor
Granulocyte_colony-stimulating_factor_receptor
Protein found in humans
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation
Colony stimulating factor 1 receptor
Colony_stimulating_factor_1_receptor
Protein-coding gene in humans
colony-stimulating factor receptor, also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating
Granulocyte-macrophage colony-stimulating factor receptor
Granulocyte-macrophage_colony-stimulating_factor_receptor
Formation of blood cellular components
Erythropoiesis-stimulating agents Haematopoietic stimulants: Granulocyte colony-stimulating factor Granulocyte macrophage colony-stimulating factor Leukocyte
Haematopoiesis
Protein or other substance that stimulates cellular proliferation
A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation
Growth_factor
Category of small signaling proteins
Granulocyte colony-stimulating factor (G-CSF), used to treat neutropenia in cancer patients Granulocyte macrophage colony-stimulating factor (GM-CSF), used
Cytokine
Receptors on the surface of cells
Leukemia inhibitory factor receptor Oncostatin M receptor Type I cytokine receptors include interleukin receptors, colony stimulating factor receptors and other
Type_I_cytokine_receptor
Medication
recombinant form of the naturally occurring granulocyte colony-stimulating factor (G-CSF). It works by stimulating the body to increase neutrophil production. Filgrastim
Filgrastim
of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization
Hematopoietic stem cell mobilization
Hematopoietic_stem_cell_mobilization
Protein that stimulates red blood cell production
have a range of actions beyond stimulation of erythropoiesis including vasoconstriction-dependent hypertension, stimulating angiogenesis, and promoting cell
Erythropoietin
Percentage of guanine and cytosine in DNA or RNA molecules
temperatures. More recently, it has been demonstrated that the most important factor contributing to the thermal stability of double-stranded nucleic acids is
GC-content
Type of signaling molecule
and IL-18, tumor necrosis factor alpha (TNF-α), interferon gamma (IFNγ), and granulocyte-macrophage colony stimulating factor (GM-CSF) and play an important
Inflammatory_cytokine
Family of intracellular tyrosine kinases
of the molecules that use the JAK/STAT signaling pathway are colony-stimulating factor, prolactin, growth hormone, and many cytokines. Janus Kinases
Janus_kinase
Chemical compound
Lenograstim is a recombinant granulocyte colony-stimulating factor which functions as an immunostimulator. It is developed by Chugai Pharmaceuticals under
Lenograstim
Pharmaceutical drug
Leukine among others, is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as an immunostimulator. It is administered
Sargramostim
growth factors and other signaling molecules. Undifferentiated bone marrow cells are cultured in the presence of macrophage colony-stimulating factor (M-CSF;
Bone marrow-derived macrophage
Bone_marrow-derived_macrophage
Group of cytokines
analysis has suggested similarity to IL4 and granulocyte-macrophage colony stimulating factor (GMCSF). Interleukin 3 (IL3) is a cytokine that regulates hematopoiesis
Interleukin
Family of biomolecules
macrophage colony-stimulating factor (M-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), and neurotactin. "Neurotrophic factors". Nature
Neurotrophic_factors
Class of immunosuppressive drug
pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response. TNF is involved in autoimmune
TNF_inhibitor
Immune system messenger protein which induces inflammation
functions including stimulating endothelial cells to induce coagulation, which obstructs blood flow to prevent the spread of microbes; stimulating endothelial
Tumor_necrosis_factor
Medication
motixafortide 1.25 mg/kg with granulocyte-colony stimulating factor (N=80) or placebo with granulocyte-colony stimulating factor (N=42) for mobilization of hematopoietic
Motixafortide
Monoclonal antibody
of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. It serves to stimulate the production of white blood cells (neutrophils)
Pegfilgrastim
Topics referred to by the same term
spine Colony-stimulating factor, secreted glycoproteins Macrophage colony-stimulating factor, "CSF-1" Granulocyte-macrophage colony-stimulating factor, "CSF-2"
CSF
subsequently, macrophages). It can be induced by macrophage colony-stimulating factor.[citation needed] It is a component of myelopoiesis. Santangelo
Monocytopoiesis
Human joint disease
tumors grow due to genetic overexpression of colony stimulating factor 1. This causes colony-stimulating factor-1 receptor (CSF1R) cells to accumulate in
Tenosynovial_giant_cell_tumor
Anatomical entity
absorption and connective tissue degradation. With the lack of colony-stimulating factor 1, a factor that encourages differentiation of osteoclasts, in osteopetrotic
Dental_follicle
Monoclonal antibody
IgG1 kappa) that targets granulocyte macrophage-colony stimulating factor (GM-CSF)/colony stimulating factor 2 (CSF2) and is currently being researched for
Namilumab
Family of proteins involved in anatomical development
kinase Granulocyte-colony stimulating factor (G-CSF) Granulocyte-macrophage colony stimulating factor (GM-CSF) Nerve growth factor (NGF) Neurotrophins
Fibroblast_growth_factor
Mammalian protein found in Homo sapiens
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, is a protein that in humans
B-cell_activating_factor
Type of cytokine
to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in Th2 cells. IL-5 is also
Interleukin_5
Chemical compound
Vimseltinib is a kinase inhibitor. Vimseltinib is a macrophage colony-stimulating factor receptor antagonist. The most common adverse reactions, including
Vimseltinib
Medical condition
messenger molecule known as granulocyte/macrophage-colony stimulating factor (GM-CSF) is unable to stimulate alveolar macrophages to clear surfactant, leading
Pulmonary alveolar proteinosis
Pulmonary_alveolar_proteinosis
Class of biochemical compounds
four catalytic steps. These authors also discovered the transcription factors Bl (Bitter leaf) and Bt (Bitter fruit) that regulate this pathway in leaves
Cucurbitacin
Mammalian protein found in Homo sapiens
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117). SCF can exist both as a transmembrane
Stem_cell_factor
Experimental drug
oral, highly potent and selective small molecule blocker of the colony-stimulating factor 1 receptor (CSF-1R) independently discovered by Abbisko Therapeutics
Pimicotinib
Cytokine produced by lymphocytes
Interleukin 4 Interleukin 5 Interleukin 6 Granulocyte-macrophage colony-stimulating factor Interferon-gamma The T helper cell secretes many lymphokines that
Lymphokine
Protein-coding gene in the species Homo sapiens
tumor microenvironment. IL-34 elicits its activity by binding the Colony stimulating factor 1 receptor. Messenger RNA (mRNA) expression of human IL-34 is
Interleukin_34
Mammalian protein found in Homo sapiens
Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced
RANKL
Formation of granulocyte cells in the bone marrow
"Induction of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) expression in bone marrow and
Granulopoiesis
Medication
sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim
Oclacitinib
Biopharmaceutical for autoimmune diseases
is used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. It
Etanercept
Medication
sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim
Ruxolitinib
Medical intervention
chemotherapy affects the production of white blood cells, a granulocyte colony-stimulating factor (G-CSF) is sometimes administered along with chemotherapy. This
Breast_cancer_chemotherapy
Class of proteins
cells of kidney. Granulocyte-macrophage colony-stimulating factor and granulocyte CSF are given to stimulate white blood cell formation in cancer patients
Hemopoietic_growth_factor
Class of proteins produced by muscle
metabolism and stimulates satellite cells, but stimulates M1 and M2 macrophages; M1 macrophages release interleukin 6 (IL-6), Insulin growth factor type 1 (IGF-1)
Myokine
Abnormally low concentration of neutrophils (a type of white blood cell) in the blood
rate of 7–10%. To manage this, the application of granulocyte colony stimulating factor (G-CSF) or granulocyte transfusion and the use of broad-spectrum
Neutropenia
Monoclonal antibody
tyrosine kinase receptor colony stimulating factor 1 receptor (CSF1R; CSF-1R; CD115), also known as macrophage colony-stimulating factor receptor (M-CSFR),
Emactuzumab
Medical condition
cancers. Most cases of SCN respond to treatment with granulocyte colony-stimulating factor (filgrastim), which increases the neutrophil count and decreases
Severe_congenital_neutropenia
Biological signaling pathway h
Phosphatase SHP-1 on Epidermal Growth Factor- and Interferon-γ-stimulated Activation of STAT Transcription Factors in HeLa Cells". Journal of Biological
JAK-STAT_signaling_pathway
Protein-coding gene in the species Homo sapiens
Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded
MST1
Signaling proteins released by host cells in response to the presence of pathogens
interleukin 1, interleukin 2, interleukin-12, tumor necrosis factor and colony-stimulating factor, can also enhance interferon production. By interacting with
Interferon
Skeletal disorder
activation of colony stimulating factor 1 receptor (CSF1R). Menopause-associated increase production of TNF-α stimulates stromal cells to produce colony stimulating
Osteoporosis
Human monoclonal antibody
antibody that inhibits the protein RANKL (receptor activator of nuclear factor kappa-Β ligand). RANKL is essential for the formation, function and survival
Denosumab
Biopharmaceutical drug
who had previously experienced inadequate response to anti–tumor necrosis factor (TNF) therapy and were currently on a stable dose of methotrexate. Participants
Upadacitinib
Pharmaceutical drug
monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). It is approved in the United States and Canada
Belimumab
Australian medical researcher (1929–2014)
the discovery of colony-stimulating factors (CSFs), including macrophage colony-stimulating factor, granulocyte colony-stimulating factor and granulocyte
Donald_Metcalf
Cytokine
production of growth factors, thereby slowing tumor growth, and inhibits other cells from producing vessel-producing growth factors, thereby blocking tumor
Interferon_type_I
InterPro Family
interferons (IFN-α and IFN-β). Meanwhile, IL-4, IL-10, transforming growth factor-beta (TGF-β) and glucocorticoids are known to downregulate type II IFN expression
Interferon_gamma
Chemical compound
(class IgG1 kappa) that targets colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF). Pre-clinical evidence and
Lenzilumab
Cell type
for monoblasts and myeloblasts. Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF). There is some controversy over which
CFU-GM
Anti-cancer medication
monoclonal antibody used in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) for people one year of age and older with relapsed or
Naxitamab
Inflammation of the alveoli of the lungs
due to a lack of evidence in this area. The use of granulocyte colony stimulating factor (G-CSF) along with antibiotics does not appear to reduce mortality
Pneumonia
Substance that stimulates the immune system
One notable example is the granulocyte macrophage colony-stimulating factor. The goal of this stimulated immune response is usually to help the body have
Immunostimulant
Medical condition
congenital neutropenia, it responds well to treatment with granulocyte colony-stimulating factor (filgrastim), which increases the neutrophil count, shortens the
Cyclic_neutropenia
Immune modulating medication
also recommends using JAK inhibitors with caution in people with risk factors for blood clots in the lungs and in deep veins (venous thromboembolism
Janus_kinase_inhibitor
Monoclonal antibody
of chronic graft-versus-host disease. It is a blocker of the colony stimulating factor-1 receptor. It is given by injection into a vein. The most common
Axatilimab
Japanese biochemist
identified Interferon in 1980 and Granulocyte colony-stimulating factor in 1986. He also identified a death factor (Fas receptor) in 1991 and its ligand (Fas
Shigekazu_Nagata
Subtype of leukocytes
dendritic cells by adding the cytokines granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin 4. Such monocyte-derived cells do, however
Monocyte
Treatment and research hospital in New York City
using human G-CSF under the name "human hematopoietic pluripotent colony stimulating factor" (P-CSF). Also in 1986, Shigekazu Nagata's team and Lawrence Souza's
Memorial Sloan Kettering Cancer Center
Memorial_Sloan_Kettering_Cancer_Center
Protein that binds to a cytokine
Lessons From the Common β Subunit of the Granulocyte-Macrophage Colony-Stimulating Factor, Interleukin-3 (IL-3), and IL-5 Receptors". Blood. 89 (5): 1471–1482
Cytokine_receptor
Chemical compound
Molgramostim is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator. Quittet P, Ceballos P, Lopez E
Molgramostim
Medication
increase the risk for pulmonary embolism. Prescribers should consider risk factors for pulmonary embolism, including age, obesity, smoking, and immobilization
Tofacitinib
Protein-coding gene in the species Homo sapiens
(January 2001). "The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A". The
Ectodysplasin_A_receptor
Medication
immunostimulant/colony stimulating factor that belongs to the class of hematopoietic growth factors (granulocyte colony stimulating factor; G CSF) which
Efbemalenograstim_alfa
Chemical compound
sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim
Eltrombopag
Medical condition
in the granulocyte-macrophage colony-stimulating factor receptor or anti-granulocyte-macrophage colony-stimulating factor autoantibodies. Last, patients
MonoMAC
Type of cytokine produced primarily by monocytes and macrophages
monokines are: interleukin 1 tumor necrosis factor-alpha alpha and beta interferon colony stimulating factors Monokines released from macrophages can attract
Monokine
Non-receptor tyrosine kinase and coding gene in humans
more sensitive to growth factors such as erythropoietin and thrombopoietin, because the receptors for these growth factors require JAK2 for signal transduction
Janus_kinase_2
secrete the immune stimulatory cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), and then irradiated to prevent further cell division
GVAX
Molecules involved in immune response
Transfer factors (which come from white cells called "T cells") are essentially small immune messenger molecules that are produced by all higher organisms
Transfer_factor
include growth factors such as insulin-like growth factor-1, and activin a transforming growth factor; cytokines such as colony stimulating factor 2, WNT regulatory
Embryokine
Mammalian protein found in humans
histocompatibility complex (MHC) molecules, proinflammatory factor production, co-stimulation of CD4+ and CD8+ T cells, and tumor cell susceptibility to
CD40
Medication to treat hair loss
sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim
Ritlecitinib
Medical intervention
Dupuis G, Amrani A (September 2007). "Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic
Tolerogenic_therapy
Pharmaceutical drug
Lipegfilgrastim is similar to granulocyte colony stimulating factor (G‑CSF), a naturally occurring protein in the body that stimulates the production of white blood
Lipegfilgrastim
Type of white blood cell
pro-angiogenic factors including vascular endothelial factor (VEGF), tumor necrosis factor-alpha (TNF-alpha), macrophage colony-stimulating factor (M-CSF/CSF1)
Macrophage
Protein found in humans
CD95L or Apo-1L) is a type-II transmembrane protein in the tumor necrosis factor (TNF) superfamily. It binds to the Fas receptor (CD95) to induce apoptosis
Fas_ligand
Mammalian protein found in Homo sapiens
inhibitory factor (OCIF) or tumour necrosis factor receptor superfamily member 11B (TNFRSF11B), is a cytokine receptor of the tumour necrosis factor (TNF)
Osteoprotegerin
Italian and Swiss immunologist
maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha". The Journal of Experimental
Antonio_Lanzavecchia
Pharmaceutical drug
sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim
Interferon_alfa
Protein found in humans
(APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans is
Fas_receptor
Glycoprotein produced in the stomach which binds to vitamin B12
Intrinsic factor (IF), also known as cobalamin binding intrinsic factor, or gastric intrinsic factor (GIF), is a glycoprotein produced by specialized cells
Intrinsic_factor
Mammalian protein and protein-coding gene
which binds to stem cell factor, also known as "steel factor" or "c-kit ligand". When this receptor binds to stem cell factor (SCF) it forms a dimer that
KIT_gene
Protein-coding gene in the species Homo sapiens
on chromosome 5q31.1. Sometimes also called colony-stimulating factor, multi-CSF, mast cell growth factor, MULTI-CSF, MCGF; MGC79398, MGC79399: after
Interleukin_3
Form of acute myeloid leukemia
AML-M4 subtype. Research regarding the production of granulocyte colony stimulating factor (G-CSF) is being conducted to investigate AMML ability to secrete
Acute_myelomonocytic_leukemia
Chemical compound
sihematide (EPO-018B) G-CSF (CSF3) Agonists: Filgrastim Granulocyte colony-stimulating factor Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim
Deuruxolitinib
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COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
COLONY STIMULATING-FACTOR
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