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CTBP1

  • CTBP1
  • Protein-coding gene in the species Homo sapiens

    known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene. CtBP1 is one of two CtBP proteins, the other protein being CtBP2. The CtBP1 protein

    CTBP1

    CTBP1

    CTBP1

  • KLF12
  • Protein-coding gene in the species Homo sapiens

    Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for

    KLF12

    KLF12

    KLF12

  • Prisca Liberali
  • Italian chemist

    closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS Liberali is married with two children. Her husband is Dutch and her

    Prisca Liberali

    Prisca Liberali

    Prisca_Liberali

  • FOXP2
  • Transcription factor gene of the forkhead box family

    certain nerve cells are also observed. FOXP2 is known to regulate CNTNAP2, CTBP1, SRPX2 and SCN3A. FOXP2 downregulates CNTNAP2, a member of the neurexin

    FOXP2

    FOXP2

    FOXP2

  • KMT2A
  • Protein-coding gene in the species Homo sapiens

    schizophrenia. MLL (gene) has been shown to interact with: ASH2L, CREBBP, CTBP1, HDAC1, HCFC1, MEN1, PPIE, PPP1R15A, RBBP5, and WDR5. KMT2A rearrangements

    KMT2A

    KMT2A

    KMT2A

  • IPEX syndrome
  • Medical condition

    interactions between the N-terminal domain and Eos - which associates with CtBP1 and forms a corepressor complex. This complex binds the IL2 promoter and

    IPEX syndrome

    IPEX syndrome

    IPEX_syndrome

  • ACTL6B
  • Protein-coding gene in the species Homo sapiens

    chromatin, specifically in the brain. ACTL6B has been shown to interact with CTBP1. GRCh38: Ensembl release 89: ENSG00000077080 – Ensembl, May 2017 GRCm38:

    ACTL6B

    ACTL6B

    ACTL6B

  • CTBP2
  • Protein-coding gene in the species Homo sapiens

    CtBP2 is a protein that in humans is encoded by the CTBP2 gene. The CtBPs - CtBP1 and CtBP2 in mammals - are among the best characterized transcriptional

    CTBP2

    CTBP2

    CTBP2

  • NRIP1
  • Protein-coding gene in the species Homo sapiens

    These motifs mediate the recruitment of the C‑terminal binding proteins CTBP1 and CTBP2. CtBP recruitment is enhanced by acetylation of NRIP1 on multiple

    NRIP1

    NRIP1

    NRIP1

  • IKZF1
  • Protein-coding gene in the species Homo sapiens

    and different forms of leukemia. IKZF1 has been shown to interact with: CTBP1, HDAC1, HDAC7A, Histone deacetylase 5, IKZF2, IKZF3, IKZF4, SIN3A, Cereblon

    IKZF1

    IKZF1

    IKZF1

  • Kruppel-like factors
  • Family of zinc finger transcription factors

    repressors via interaction with the C-terminal Binding Protein 1 and 2 (CtBP1 and CtBP2). Group 2 (KLFs 1,2,4,5,6, and 7) are transcription activators

    Kruppel-like factors

    Kruppel-like_factors

  • Mdm2
  • Protein-coding gene in humans

    function. Mdm2 has been shown to interact with: ABL1, ARRB1, ARRB2, CCNG1, CTBP1, CTBP2, DAXX, DHFR, EP300, ERICH3, FKBP3, FOXO4, GNL3, HDAC1, HIF1A, HTATIP

    Mdm2

    Mdm2

    Mdm2

  • DNA end resection
  • Process involved in DNA repair

    where this complex is called the MRX complex). Before resection can start, CtBP1-interacting protein (CtIP) needs to bind to the MRN complex so that the

    DNA end resection

    DNA end resection

    DNA_end_resection

  • Housekeeping gene
  • Gene which maintains basic cellular functions

    NM_014504 RABGGTA NM_004581 RABGGTB NM_004582 CENPB Centromere protein B CTBP1 Centromere protein T CCNB1IP1 NM_021178 E3 ubiquitin-protein ligase. Modulates

    Housekeeping gene

    Housekeeping_gene

  • ZFPM2
  • Protein-coding gene in the species Homo sapiens

    and histone deacetylase complex or NuRD complex) and other of which binds CTBP1 or CTBP2 proteins. The NuRD complex and the CtBPs are classified as corepressors

    ZFPM2

    ZFPM2

    ZFPM2

  • GATA1
  • Protein-coding gene in humans

    expression-regulating complexes, Mi-2/NuRD complex (a chromatin remodeler) and CTBP1 (a histone deacetylase) and three gene expression-regulating proteins, SET8

    GATA1

    GATA1

    GATA1

  • IKZF4
  • Human gene

    lymphoid development.[supplied by OMIM] IKZF4 has been shown to interact with CTBP1 and IKZF1. GRCh38: Ensembl release 89: ENSG00000123411 – Ensembl, May 2017

    IKZF4

    IKZF4

    IKZF4

  • List of human protein-coding genes 2
  • P0CG41 3718 CTAGE9 HGNC:37275; A4FU28 3719 CTAGE15 HGNC:37295; A4D2H0 3720 CTBP1 HGNC:2494; Q13363 3721 CTBP2 HGNC:2495; P56545 3722 CTBS HGNC:2496; Q01459

    List of human protein-coding genes 2

    List_of_human_protein-coding_genes_2

  • Paul Khavari
  • Carl J. Hezrog Professor at the Stanford University School of Medicine

    (15 September 2014). "ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce

    Paul Khavari

    Paul_Khavari

  • RBBP8
  • Protein-coding gene in the species Homo sapiens

    inhibitor treatment. RBBP8 has been shown to interact with: ATM, BRCA1, CTBP1, LMO4, RB1, RBL1, RBL2, and SIAH1 GRCh38: Ensembl release 89: ENSG00000101773

    RBBP8

    RBBP8

    RBBP8

  • KLF3
  • Protein-coding gene in the species Homo sapiens

    It does this by recruiting the C-terminal Binding Protein co-repressors CTBP1 and CTBP2. CtBP docks onto a short motif (residues 61-65) in the N-terminus

    KLF3

    KLF3

    KLF3

  • Pinin
  • Protein-coding gene in the species Homo sapiens

    Pinin has been shown to interact with Keratin 8, Keratin 18, Keratin 19, CTBP1, RNPS1, PRPF4B, SFRS4, PPIG, SRRM2 and SFRS18. GRCh38: Ensembl release 89:

    Pinin

    Pinin

    Pinin

  • ZNF366
  • Protein-coding gene in the species Homo sapiens

    an acidic region, which can interact with C-terminal-binding protein 1 (CtBP1), a global corepressor. In the immune system of both mice and humans, DC-SCRIPT

    ZNF366

    ZNF366

    ZNF366

  • HDAC1
  • Protein-coding gene in humans

    BTG2, BUB1B, BUB1, BUB3, CBFA2T3, CDC20, CDH1, CHD3, CHD4, COUP-TFII, CTBP1, DDX17, DDX5, DNMT3A, DNMT3L, Death-associated protein 6, EED, EVI1, EZH2

    HDAC1

    HDAC1

    HDAC1

  • Benita Katzenellenbogen
  • American professor of physiology and cell biology

    Receptor Alpha Represses Transcription of Early Target Genes via p300 and CtBP1". Molecular and Cellular Biology. 29 (7): 1749–59. doi:10.1128/MCB.01476-08

    Benita Katzenellenbogen

    Benita_Katzenellenbogen

  • MECOM
  • Protein-coding gene in the species Homo sapiens

    insertions. MECOM has been shown to interact with: CREB binding protein CTBP1 HDAC1 Mothers against decapentaplegic homolog 3 PCAF GRCh38: Ensembl release

    MECOM

    MECOM

    MECOM

  • HIPK2
  • Protein-coding gene in the species Homo sapiens

    enhances p53 activity by phosphorylating negative regulators of p53, such as CtBP1 and Mdm2, leading to their degradation by the proteasome. HIPK2 also has

    HIPK2

    HIPK2

    HIPK2

  • EEF1D
  • Protein-coding gene in the species Homo sapiens

    Furusawa T, Moribe H, Kondoh H, Higashi Y (Dec 1999). "Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1". Molecular

    EEF1D

    EEF1D

    EEF1D

  • Homeobox protein TGIF1
  • Protein found in humans

    middle ear) Homeobox protein TGIF1 has been shown to interact with: C-jun, CTBP1, HDAC1, and Mothers against decapentaplegic homolog 2. GRCh38: Ensembl release

    Homeobox protein TGIF1

    Homeobox protein TGIF1

    Homeobox_protein_TGIF1

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