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Protein-coding gene in the species Homo sapiens
Homeobox protein CDX-1 is a protein in humans that is encoded by the CDX1 gene. CDX-1 is expressed in the developing endoderm and its expression persists
Homeobox_protein_CDX-1
Protein found in humans
Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene. The CDX-2 protein is a homeobox transcription factor expressed in the
Homeobox_protein_CDX-2
Protein family
The Cdx protein family is a group of the transcription factor proteins which bind to DNA to regulate the expression of genes. In particular this family
Cdx_protein_family
Human protein
BARX homeobox 1 is a protein that in humans is encoded by the BARX1 gene. This gene encodes a member of the Bar subclass of homeobox transcription factors
BARX_homeobox_1
Protein-coding gene in humans
Homeobox protein CDX-4 is a protein that in humans is encoded by the CDX4 gene. This gene is a member of the caudal-related homeobox transcription factor
Homeobox_protein_CDX-4
DNA pattern affecting anatomy development
cell eukaryotes. Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that
Homeobox
Protein found in humans
Homeobox protein cut-like 1 is a protein that in humans is encoded by the CUX1 gene (previously CUTL1). This protein is a homeodomain protein. The term
Homeobox_protein_cut-like_1
Protein-coding gene in the species Homo sapiens
Homeobox protein MSX-1, is a protein that in humans is encoded by the MSX1 gene. MSX1 transcripts are not only found in thyrotrope-derived TSH cells, but
Homeobox_protein_MSX-1
Mammalian protein found in Homo sapiens
NK2 homeobox 1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the NKX2-1 gene. Thyroid transcription
NK2_homeobox_1
Group of genes
The Cdx gene family, also called caudal genes, are a group of genes found in many animal genomes. Cdx genes contain a homeobox DNA sequence and code for
Cdx
Protein-coding gene in humans
Homeobox protein Nkx-2.5 is a protein that in humans is encoded by the NKX2-5 gene. Homeobox-containing genes play critical roles in regulating tissue-specific
Homeobox_protein_Nkx-2.5
Protein-coding gene in humans
Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene. In vertebrates, the genes encoding the class of transcription factors
Homeobox_A10
Protein-coding gene in humans
Homeobox protein SIX1 (Sine oculis homeobox homolog 1) is a protein that in humans is encoded by the SIX1 gene. The vertebrate SIX genes are homologs
Homeobox_protein_SIX1
Protein-coding gene in humans
Homeobox protein Hox-A1 is a protein that in humans is encoded by the HOXA1 gene. Two transcript variants encoding two different isoforms have been found
Homeobox_A1
Protein family
The family of heterochromatin protein 1 (HP1) ("Chromobox Homolog", CBX) consists of highly conserved proteins, which have important functions in the cell
Heterochromatin_protein_1
Protein-coding gene in the species Homo sapiens
LIM/homeobox protein Lhx3 is a protein that in humans is encoded by the LHX3 gene. LHX3 encodes a protein of a large protein family, members of which carry
LHX3
Mammalian protein found in humans
Homeobox protein NANOG (hNanog) is a transcriptional factor that helps embryonic stem cells (ESCs) maintain pluripotency by suppressing cell determination
Homeobox_protein_NANOG
Protein-coding gene in the species Homo sapiens
Retinal homeobox protein Rx also known as retina and anterior neural fold homeobox is a protein that in humans is encoded by the RAX gene. The RAX gene
Retinal_homeobox_protein_Rx
Protein
Prospero homeobox protein 2 is a protein that in humans is encoded by the PROX2 gene. Nishijima I, Ohtoshi A (Feb 2006). "Characterization of a novel
PROX2
Protein involved in the pancreas and duodenum differentiation
PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster. In vertebrates
PDX1
Protein-coding gene in humans
Prospero homeobox protein 1 is a protein that in humans is encoded by the PROX1 gene. The Prox1 gene is critical for the development of multiple tissues
PROX1
Protein-coding gene in the species Homo sapiens
Homeobox protein OTX2 is a protein that in humans is encoded by the OTX2 gene. This gene encodes a member of the bicoid sub-family of homeodomain-containing
Orthodenticle_homeobox_2
Protein-coding gene in humans
Homeobox protein Nkx-6.1 is a protein that in humans is encoded by the NKX6-1 gene. In the pancreas, NKX6.1 is required for the development of beta cells
NKX6-1
Protein-coding gene in the species Homo sapiens
Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX (mohawk homeobox) gene. MKX
MKX
Protein that initiates male sex determination in therian mammals
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor)
Sex-determining region Y protein
Sex-determining_region_Y_protein
Protein-coding gene in humans
Aristaless related homeobox is a protein that in humans is encoded by the ARX gene. This gene is a homeobox-containing gene expressed during development
Aristaless_related_homeobox
Protein-coding gene in the species Homo sapiens
leukemia homeobox protein 3 is a protein that in humans is encoded by the TLX3 gene. RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that
TLX3
Human protein and coding gene
ARNT-like protein 1 or aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL), or brain and muscle ARNT-like 1 is a protein that in humans
Basic helix-loop-helix ARNT-like protein 1
Basic_helix-loop-helix_ARNT-like_protein_1
Protein-coding gene in the species Homo sapiens
Paired-like homeobox 2b (PHOX2B), also known as neuroblastoma Phox (NBPhox), is a protein that in humans is encoded by the PHOX2B gene located on chromosome
PHOX2B
GS homeobox 1 (GSX1) is a protein encoded by the gene of the same name, located on chromosome 13 in humans and chromosome 5 in mice. GSX1 is part of the
GSX1
Genes regulating the development of anatomical structures in various organisms
they were first discovered) and humans. Hox genes are a subset of the homeobox genes. The Hox genes are often conserved across species, so some of the
Homeotic_gene
Protein-coding gene in humans
the mitogen-activated protein kinase (MAPK/ERK pathway), particularly to the activity of mitogen-activated protein kinase kinase-1 (MEK1). Studies have
SMAD3
Mammalian protein found in humans
cancer 4) is a highly conserved protein present in all metazoans. It belongs to the SMAD family of transcription factor proteins, which act as mediators of
SMAD4
Protein-coding gene in the species Homo sapiens
Baltimore D (February 1990). "A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL". Cell. 60 (4): 547–555
TCF3
Protein-coding gene in the species Homo sapiens
Iroquois-class homeodomain protein IRX-5, also known as Iroquois homeobox protein 5, is a protein that in humans is encoded by the IRX5 gene. IRX5 is a
IRX5
Protein-coding gene in humans
Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. PAX6
PAX6
Mammalian protein found in Homo sapiens
Homeobox protein DLX-5 is a protein that in humans is encoded by the distal-less homeobox 5 gene, or DLX5 gene. DLX5 is a member of the DLX gene family
DLX5
Protein-coding gene in humans
transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) and it is a protein that is encoded
RUNX1
Protein-coding gene in the species Homo sapiens
Homeobox protein Hox-A13 is a protein that in humans is encoded by the HOXA13 gene. In vertebrates, the genes encoding the class of transcription factors
HOXA13
Family of transcription factors
particularly teeth. It transcribes a protein of 341 amino acids from 4 exons and 1,644bps in humans. Homeobox Evolutionary developmental biology Body
Pax_genes
Protein-coding gene in the species Homo sapiens
Homeobox protein Emx2 is a protein that in humans is encoded by the EMX2 gene. The homeodomain transcription factor EMX2 is critical for central nervous
EMX2
Protein-coding gene in the species Homo sapiens
non-receptor tyrosine kinase (non-receptor TK), homeobox protein type of transcription factor (homeobox protein), acute lymphocytic leukemia (ALL), Philadelphia
ETV6
Protein-coding gene in the species Homo sapiens
EGR-1 (Early growth response protein 1) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is
EGR1
Vertebrate receptor protein and transcription factor
known as AhR, AHR, ahr, ahR, AH receptor, or as the dioxin receptor) is a protein that in humans is encoded by the AHR gene. The aryl hydrocarbon receptor
Aryl_hydrocarbon_receptor
Protein-coding gene in humans
Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. In humans, the DMRT1
DMRT1
Mammalian protein found in humans
transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded by the MITF gene. MITF is a basic
Microphthalmia-associated transcription factor
Microphthalmia-associated_transcription_factor
Protein-coding gene in humans
Homeobox Protein HB24 is a protein that in humans is encoded by the HLX gene. Hlx belongs to the class of homeobox transcription factors, initially cloned
HLX_(gene)
GS homeobox 2 (GSX2) is a protein encoded by a gene of the same name, located on chromosome 4 in humans, and on chromosome 5 in mice. It is especially
GSX2
Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)
Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors
AP-1_transcription_factor
Protein-coding gene in the species Homo sapiens
Testis-expressed protein 9 is a protein that in humans is encoded the TEX9 gene. TEX9 that encodes a 391-long amino acid protein containing two coiled-coil
TEX9
Mammalian protein found in Homo sapiens
encodes hepatocyte nuclear factor 1-beta, a protein of the homeobox-containing basic helix-turn-helix family. The HNF1B protein is believed to form heterodimers
HNF1B
Protein-coding gene in the species Homo sapiens
class 3, transcription factor 2 is a protein that in humans is encoded by the POU3F2 gene. N-Oct-3 is a protein belonging to a large family of transcription
POU3F2
Human protein and coding gene
promoter regions of genes encoding cytoprotective proteins. NRF2 induces the expression of heme oxygenase 1 in vitro leading to an increase in phase II enzymes
NFE2L2
Human gene
Homeobox protein prophet of PIT-1 is a protein that in humans is encoded by the PROP1 gene. PROP1 has both DNA-binding and transcriptional activation ability
PROP1
Family of transcription factor protein complexes
of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell
NF-κB
Protein-coding gene in the species Homo sapiens
Heat shock factor protein 1 (HSF 1) is a protein that in humans is encoded by the HSF1 gene. HSF1 is highly conserved in eukaryotes and is the primary
Heat_shock_factor_protein_1
Mammalian protein found in Homo sapiens
box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. HMG-1 belongs
HMGB1
Gene cluster
array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx, Xlox (Pdx) and Cdx gene families
ParaHox
Transcription factor gene of the forkhead box family
Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene. FOXP2 is a member of the forkhead box family of transcription
FOXP2
Protein molecule receiving signals for a cell
In biochemistry and pharmacology, receptors are proteins that receive and transduce signals that may be integrated into biological systems. These signals
Receptor_(biochemistry)
Protein that responds to low oxygen
that muscle A kinase–anchoring protein (mAKAP) organized E3 ubiquitin ligases, affecting stability and positioning of HIF-1 inside its action site in the
Hypoxia-inducible_factor
Protein-coding gene in humans
BarH-like homeobox 2 is a protein in humans that is encoded by the BARHL2 gene. GRCh38: Ensembl release 89: ENSG00000143032 – Ensembl, May 2017 GRCm38:
BARHL2
Protein-coding gene in the species Homo sapiens
Homeobox protein Hox-C9 is a protein that in humans is encoded by the HOXC9 gene. This gene belongs to the homeobox family of genes. The homeobox genes
HOXC9
Protein-coding gene in the species Homo sapiens
encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation
BAZ1B
General transcription factors
promoters of protein-coding genes in living cells. It consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known
Transcription_factor_II_D
Protein domain
Leucine Zipper Domain (bZIP domain) is found in many DNA binding eukaryotic proteins. One part of the domain contains a region that mediates sequence specific
BZIP_domain
Protein-coding gene in humans
Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene. This gene belongs to the homeobox family of genes. The homeobox genes
HOXC13
Genes that affect limb and heart development
development. Every T-box protein has a relatively large DNA-binding domain, generally comprising about a third of the entire protein that is both necessary
T-box
Protein-coding gene in the species Homo sapiens
finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene. The protein encoded
ZFP57
Protein family
high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box reported
MADS-box
Engineered zinc finger protein
C7 protein is an engineered zinc finger protein based on the murine ZFP, Zif268 and discovered by Wu et al. in 1994 (published in 1995). It shares the
C7_protein
Protein-coding gene in the species Homo sapiens
proteins MAVS, STING and TRIF at a conserved pLxIS motif recruits and specifies IRF3 phosphorylation and activation by the Serine/threonine-protein kinase
IRF3
Protein-coding gene in the species Homo sapiens
Mesenchyme homeobox 1 (MEOX1) is a protein that in humans is encoded by the MEOX1 gene. This gene encodes a member of a subfamily of non-clustered, diverged
MEOX1
Protein-coding gene in the species Homo sapiens
Hematopoietically-expressed homeobox protein HHEX is a protein that in humans is encoded by the HHEX gene and also known as Proline Rich Homeodomain protein PRH. This gene
HHEX
Protein-coding gene in humans
other processes within the cell. Twist, Msh homeobox 2 (Msx2), and promyelocytic leukemia zinc-finger protein (PLZF) act upstream of Runx2. Osterix (Osx)
RUNX2
Paired box gene 3
longest isoform and consists of 10 exons that encode a 505 amino acid protein. In other mammalian species, including mouse, the longest mRNAs correspond
PAX3
Protein-coding gene in the species Homo sapiens
Homeobox protein Hox-B8 is a protein that in humans is encoded by the HOXB8 gene. This gene is a member of the Antp homeobox family and encodes a nuclear
HOXB8
Protein-coding gene in humans
SANT/Myb family also include the SANT domain and other similar all-helical homeobox-like domains. The Myb gene family is named after the eponymous gene in
MYB_(gene)
Group of proteins
(High-Mobility Group Nucleosome-binding) proteins are members of the broader class of high-mobility group (HMG) chromosomal proteins that are involved in regulation
HMGN
Mammalian protein found in humans
The retinoblastoma protein (protein name abbreviated Rb or pRb; gene name abbreviated Rb, RB or RB1) is a tumor suppressor protein that is dysfunctional
Retinoblastoma_protein
Mammalian protein found in Homo sapiens
4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene. Oct-4 is a homeodomain
Oct-4
Protein-coding gene in the species Homo sapiens
Twist-related protein 2 is a protein that in humans is encoded by the TWIST2 gene. The protein encoded by this gene is a basic helix-loop-helix (bHLH)
Twist-related_protein_2
Protein-coding gene in humans
Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene. This gene is a member of the Antp homeobox family and encodes a nuclear
HOXB2
Protein
Homeobox protein Hox-D13 is a protein that in humans is encoded by the HOXD13 gene. This gene belongs to the homeobox family of genes. The homeobox genes
HOXD13
Protein-coding gene in the species Homo sapiens
Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 protein is a transcription factor that plays a role
ZEB2
Mammalian protein found in Homo sapiens
for "nuclear receptor subfamily 4 group A member 1") also known as Nur77, TR3, and NGFI-B is a protein that in humans is encoded by the NR4A1 gene. Nuclear
Nuclear_receptor_4A1
Protein-coding gene in the species Homo sapiens
Homeobox protein Hox-B13 is a protein that in humans is encoded by the HOXB13 gene. This gene encodes a transcription factor that belongs to the homeobox
HOXB13
Protein-coding gene in the species Homo sapiens
factor hypoxia-inducible factor (HIF1). Its protein expression level can be measured by antibodies against HIF-1-alpha through various biological detection
HIF1A
Protein-coding gene in the species Homo sapiens
Homeobox protein SIX3 is a protein that in humans is encoded by the SIX3 gene. The SIX homeobox 3 (SIX3) gene is crucial in embryonic development by providing
SIX3
Protein-coding gene in the species Homo sapiens
Homeobox protein Nkx-3.1, also known as NKX3-1, NKX3, BAPX2, NKX3A and NKX3.1 is a protein that in humans is encoded by the NKX3-1 gene located on chromosome
NKX3-1
Protein that controls rate of transcription of GH genes
POU class 1 homeobox 1, also known as pituitary-specific positive transcription factor 1 (PIT1), POU domain, class 1, transcription factor 1 (POU1F1) and
Pituitary-specific positive transcription factor 1
Pituitary-specific_positive_transcription_factor_1
Protein-coding gene in humans
The steroidogenic factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling the activity of genes related to the reproductive
Steroidogenic_factor_1
Nuclear receptor protein found in humans
also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans
Peroxisome proliferator-activated receptor alpha
Peroxisome_proliferator-activated_receptor_alpha
Mammalian protein found in humans
p53, also known as tumor protein p53, TP53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory transcription
P53
Group of proteins
Region Y Protein SOX1, SOX2, etc. TCF/LEF family (T cell factor/lymphoid enhancer factor family) LEF1 (Lymphoid enhancer-binding factor 1) TCF7 (TCF-1) TCF7L1
High-mobility_group
Protein-coding gene in the species Homo sapiens
Zinc finger E-box-binding homeobox 1 is a protein that in humans is encoded by the ZEB1 gene. ZEB1 (previously known as TCF8) encodes a zinc finger and
ZEB1
Protein-coding gene in the species Homo sapiens
Motor neuron and pancreas homeobox 1 (MNX1), also known as Homeobox HB9 (HLXB9), is a human protein encoded by the MNX1 gene. Mutations in the MNX1 gene
MNX1
Protein-coding gene in the species Homo sapiens
factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. The protein encoded by this gene is a zinc finger
Transcription_factor_Sp1
Protein-coding gene in the species Homo sapiens
Homeobox protein engrailed-1 is a protein that in humans is encoded by the EN1 gene. Homeobox-containing genes are thought to have a role in controlling
EN1_(gene)
Family of proteins
using a protein domain called a winged-helix domain. In some cases, the term has been used to refer specifically to the family of FOX proteins, where the
Winged-helix transcription factors
Winged-helix_transcription_factors
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HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
Surname or Lastname
English
English : possibly a variant of Porton, a habitational name from Porton in Wiltshire or Poorton in Dorset; both place names are formed with an obscure first element, perhaps the name of a river, + Old English tūn ‘settlement’.Dutch : habitational name for someone from a place named with Dutch poort ‘gate’.
Surname or Lastname
English
English : variant of Cox.
Girl/Female
Arabic, Australian, Muslim
Protect
Surname or Lastname
English
English : from Cocke in any the senses described + the suffix -s denoting ‘son of’ or ‘servant of’.Irish (Ulster) : mistranslation of Mac Con Coille (‘son of Cú Choille’, a personal name meaning ‘hound of the wood’), as if formed with coileach ‘cock’, ‘rooster’.
Girl/Female
Tamil
Rakshitha | ரகà¯à®·à®¿à®¤à®¾, ரகà¯à®·à¯€à®¤à®¾Â
Who protect
Rakshitha | ரகà¯à®·à®¿à®¤à®¾, ரகà¯à®·à¯€à®¤à®¾Â
Girl/Female
Tamil
Rakshita | ரகà¯à®·à®¿à®¤à®¾, ரகà¯à®·à¯€à®¤à®¾Â
Who protect
Rakshita | ரகà¯à®·à®¿à®¤à®¾, ரகà¯à®·à¯€à®¤à®¾Â
Girl/Female
Hindu, Indian
Protect
Boy/Male
Hindu
Boy/Male
German, Polish
To Protect
Girl/Female
Hindu
Who protect
Girl/Female
Hindu
Who protect
Boy/Male
Greek Shakespearean
A sea god.
Boy/Male
Bengali, Indian
Symbol
Boy/Male
Bengali, Indian
Love
Boy/Male
Hindu, Indian
Proven
Surname or Lastname
English
English : derivative of Adcock. Compare Cox.
Girl/Female
Afghan, Arabic, Australian, Danish, French, Hebrew, Muslim
Protect
Boy/Male
English, Hebrew
Protect; Heel
Surname or Lastname
English
English : variant spelling of Cox.
Surname or Lastname
English and French
English and French : regional name from Old French Poitevin, denoting someone from Poitou in western France. The form Potvin has long been established in England and was brought to the U.S. from there. However, French bearers of the surname Poitevin also came to the New World, where their surname underwent a similar transformation on arrival in New England.
HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
HOMEOBOX PROTEIN-CDX-1
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