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HYDROXYCHOLESTEROL

  • 24S-Hydroxycholesterol
  • Chemical compound

    24S-Hydroxycholesterol (24S-HC), also known as cholest-5-ene-3,24-diol or cerebrosterol, is an endogenous oxysterol produced by neurons in the brain to

    24S-Hydroxycholesterol

    24S-Hydroxycholesterol

    24S-Hydroxycholesterol

  • 25-Hydroxycholesterol
  • Chemical compound

    25-Hydroxycholesterol is a derivative of cholesterol, which plays a role in various biological processes in humans and other species. It is involved in

    25-Hydroxycholesterol

    25-Hydroxycholesterol

    25-Hydroxycholesterol

  • 27-Hydroxycholesterol
  • Chemical compound

    27-Hydroxycholesterol (27-HC) is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator

    27-Hydroxycholesterol

    27-Hydroxycholesterol

    27-Hydroxycholesterol

  • Hydroxycholesterol
  • Index of chemical compounds with the same name

    Hydroxycholesterol may refer to: 7α-Hydroxycholesterol 20S-Hydroxycholesterol 22R-Hydroxycholesterol (22(R)-Hydroxycholesterol) Cerebrosterol (24(S)-Hydroxycholesterol)

    Hydroxycholesterol

    Hydroxycholesterol

  • 27-hydroxycholesterol 7alpha-monooxygenase
  • Class of enzymes

    enzymology, a 27-hydroxycholesterol 7alpha-monooxygenase (EC 1.14.13.60) is an enzyme that catalyzes the chemical reaction 27-hydroxycholesterol + NADPH + H+

    27-hydroxycholesterol 7alpha-monooxygenase

    27-hydroxycholesterol_7alpha-monooxygenase

  • 7α-Hydroxycholesterol
  • Chemical compound

    7α-Hydroxycholesterol is a precursor of bile acids, created by cholesterol 7α-hydroxylase (CYP7A1). Its formation is the rate-determining step in bile

    7α-Hydroxycholesterol

    7α-Hydroxycholesterol

    7α-Hydroxycholesterol

  • 20S-Hydroxycholesterol
  • Chemical compound

    20S-Hydroxycholesterol is a steroid of the oxysterol class. It is a human metabolite of cholesterol. 20S-Hydroxycholesterol has been the subject of research

    20S-Hydroxycholesterol

    20S-Hydroxycholesterol

    20S-Hydroxycholesterol

  • 22R-Hydroxycholesterol
  • Chemical compound

    22R-Hydroxycholesterol, or (3β)-cholest-5-ene-3,22-diol is an endogenous, metabolic intermediate in the biosynthesis of the steroid hormones from cholesterol

    22R-Hydroxycholesterol

    22R-Hydroxycholesterol

    22R-Hydroxycholesterol

  • 24-hydroxycholesterol 7alpha-hydroxylase
  • Class of enzymes

    enzymology, a 24-hydroxycholesterol 7alpha-hydroxylase (EC 1.14.14.26) is an enzyme that catalyzes the chemical reaction 24S-hydroxycholesterol + NADPH    

    24-hydroxycholesterol 7alpha-hydroxylase

    24-hydroxycholesterol 7alpha-hydroxylase

    24-hydroxycholesterol_7alpha-hydroxylase

  • 25-hydroxycholesterol 7α-hydroxylase
  • Class of enzymes

    25-hydroxycholesterol 7alpha-hydroxylase (EC 1.14.13.100, 25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase) is an

    25-hydroxycholesterol 7α-hydroxylase

    25-hydroxycholesterol_7α-hydroxylase

  • Cholesterol 25-hydroxylase
  • Class of enzymes

    chemical reaction Cholesterol + reduced acceptor     O2 H2O       25-Hydroxycholesterol + electron acceptor   The three substrates of this enzyme are cholesterol

    Cholesterol 25-hydroxylase

    Cholesterol 25-hydroxylase

    Cholesterol_25-hydroxylase

  • Cholesterol 7 alpha-hydroxylase
  • Enzyme found in humans

    cholesterol via the classic pathway, catalyzing the formation of 7α-hydroxycholesterol. In humans, it is encoded by the CYP7A1 gene. It is a cytochrome P450

    Cholesterol 7 alpha-hydroxylase

    Cholesterol 7 alpha-hydroxylase

    Cholesterol_7_alpha-hydroxylase

  • Cholesterol 24-hydroxylase
  • Protein family

    is an enzyme that catalyzes the conversion of cholesterol to 24S-hydroxycholesterol. It is responsible for the majority of cholesterol turnover in the

    Cholesterol 24-hydroxylase

    Cholesterol 24-hydroxylase

    Cholesterol_24-hydroxylase

  • C27H46O2
  • Index of chemical compounds with the same molecular formula

    refer to: Hydroxycholesterols 7α-Hydroxycholesterol 22R-Hydroxycholesterol(22(R)-Hydroxycholesterol) Cerebrosterol (24(S)-Hydroxycholesterol) 25-Hydroxycholesterol

    C27H46O2

    C27H46O2

  • 20α,22R-Dihydroxycholesterol
  • Chemical compound

    hydroxylated by cholesterol side-chain cleavage enzyme (P450scc) to form 22R-hydroxycholesterol, which is subsequently hydroxylated again by P450scc to form 20α

    20α,22R-Dihydroxycholesterol

    20α,22R-Dihydroxycholesterol

    20α,22R-Dihydroxycholesterol

  • Ketamine
  • Dissociative anesthetic and anti-depressant

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Ketamine

    Ketamine

    Ketamine

  • List of neurosteroids
  • receptors and can quickly influence central nervous system function. 25-Hydroxycholesterol: cholest-5-en-3β,25-diol – NMDA receptor negative allosteric modulator

    List of neurosteroids

    List of neurosteroids

    List_of_neurosteroids

  • HSD3B7
  • Enzyme found in humans

    The primary reaction is to convert 7α-hydroxycholesterol to 7α-hydroxycholest-4-en-3-one: 7α-hydroxycholesterol + NAD+       H+   H+   7α-hydroxycholest-4-en-3-one

    HSD3B7

    HSD3B7

    HSD3B7

  • Bile acid
  • Steroid acid in the bile of animals

    hydroxyl group by cholesterol 7α-hydroxylase (CYP7A1) forming 7α-hydroxycholesterol. This is then metabolised to 7α-hydroxy-4-cholesten-3-one. There are

    Bile acid

    Bile_acid

  • Saffron
  • Spice made from crocus flowers

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Saffron

    Saffron

    Saffron

  • Fluorexetamine
  • Chemical compound

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Fluorexetamine

    Fluorexetamine

    Fluorexetamine

  • Cerebrotendinous xanthomatosis
  • Genetic bile acid metabolism disorder

    atherosclerosis, with patients experiencing elevated levels of 27-hydroxycholesterol and decreased high-density lipoprotein cholesterol. CTX patients often

    Cerebrotendinous xanthomatosis

    Cerebrotendinous xanthomatosis

    Cerebrotendinous_xanthomatosis

  • CYP39A1
  • Protein-coding gene in the species Homo sapiens

    Its substrates include the oxysterols 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol. GRCh38: Ensembl release 89: ENSG00000146233

    CYP39A1

    CYP39A1

    CYP39A1

  • Pharmacology of ethanol
  • Pharmacodynamics and pharmacokinetics of ethanol

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Pharmacology of ethanol

    Pharmacology of ethanol

    Pharmacology_of_ethanol

  • 7α-Hydroxy-4-cholesten-3-one
  • Chemical compound

    biochemical synthesis of bile acids from cholesterol. Its precursor, 7α-hydroxycholesterol, is produced from cholesterol by hepatic cholesterol 7α-hydroxylase

    7α-Hydroxy-4-cholesten-3-one

    7α-Hydroxy-4-cholesten-3-one

    7α-Hydroxy-4-cholesten-3-one

  • Cholesterol 7alpha-monooxygenase
  • Enzyme

    cholesterol + NADPH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons } 7alpha-hydroxycholesterol + NADP+ + H2O The 4 substrates of this enzyme are cholesterol, NADPH

    Cholesterol 7alpha-monooxygenase

    Cholesterol_7alpha-monooxygenase

  • Prostaglandin F2alpha
  • Chemical compound

    Dhawan V (June 2010). "Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis". Fertility and Sterility

    Prostaglandin F2alpha

    Prostaglandin F2alpha

    Prostaglandin_F2alpha

  • Steroidogenic acute regulatory protein, mitochondrial
  • Protein-coding gene in the species Homo sapiens

    macrophage, where it can stimulate the production of 27-hydroxycholesterol. In this case, 27-hydroxycholesterol may by itself be helpful against the production

    Steroidogenic acute regulatory protein, mitochondrial

    Steroidogenic acute regulatory protein, mitochondrial

    Steroidogenic_acute_regulatory_protein,_mitochondrial

  • Tramadol
  • Synthetic opioid pain medication

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Tramadol

    Tramadol

    Tramadol

  • 6β-Hydroxycortisol
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    6β-Hydroxycortisol

    6β-Hydroxycortisol

    6β-Hydroxycortisol

  • Cortisol
  • Vertebrate natural glucocorticoid hormone

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Cortisol

    Cortisol

    Cortisol

  • Adrenal steroid
  • Class of chemical compounds

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Adrenal steroid

    Adrenal_steroid

  • Estrogen
  • Primary female sex hormone

    estrogens, the biosyntheses of which do not involve aromatase, include 27-hydroxycholesterol, dehydroepiandrosterone (DHEA), 7-oxo-DHEA, 7α-hydroxy-DHEA, 16α-hydroxy-DHEA

    Estrogen

    Estrogen

    Estrogen

  • Hydrochlorothiazide
  • Diuretic medication

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Hydrochlorothiazide

    Hydrochlorothiazide

    Hydrochlorothiazide

  • Androstadienone
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Androstadienone

    Androstadienone

    Androstadienone

  • Cortisone
  • Corticosteroid precursor and metabolite of cortisol

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Cortisone

    Cortisone

    Cortisone

  • RAP-219
  • Pharmaceutical compound

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    RAP-219

    RAP-219

  • Ibogaine
  • Psychoactive substance found in plants in the family Apocynaceae

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Ibogaine

    Ibogaine

    Ibogaine

  • Glucocorticoid
  • Class of corticosteroids

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Glucocorticoid

    Glucocorticoid

    Glucocorticoid

  • Barbiturate
  • Class of depressant drugs derived from barbituric acid

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Barbiturate

    Barbiturate

    Barbiturate

  • Chenodeoxycholic acid
  • One of the main bile acids

    LXRTooltip Liver X receptor Agonists: 22R-Hydroxycholesterol 24S-Hydroxycholesterol 27-Hydroxycholesterol Abequolixron Cholestenoic acid DMHCA GW-3965

    Chenodeoxycholic acid

    Chenodeoxycholic acid

    Chenodeoxycholic_acid

  • Carbenoxolone
  • Chemical compound

    reversibly catalyzes the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. Carbenoxolone is a modestly potent, reasonably effective, water-soluble

    Carbenoxolone

    Carbenoxolone

    Carbenoxolone

  • Senolytic
  • Type of molecule that may be able to induce death of senescent cells

    Perez K, Clayton ZS, et al. (February 2022). "Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types". iScience. 25 (2) 103848. Bibcode:2022iSci

    Senolytic

    Senolytic

  • Alcohol (drug)
  • Active ingredient in fermented drinks

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Alcohol (drug)

    Alcohol (drug)

    Alcohol_(drug)

  • Obeticholic acid
  • Chemical compound

    LXRTooltip Liver X receptor Agonists: 22R-Hydroxycholesterol 24S-Hydroxycholesterol 27-Hydroxycholesterol Abequolixron Cholestenoic acid DMHCA GW-3965

    Obeticholic acid

    Obeticholic acid

    Obeticholic_acid

  • CYP7B1
  • Protein-coding gene in the species Homo sapiens

    25-hydroxycholesterol 7-alpha-hydroxylase also known as oxysterol and steroid 7-alpha-hydroxylase is an enzyme that in humans is encoded by the CYP7B1

    CYP7B1

    CYP7B1

    CYP7B1

  • NMDA receptor antagonist
  • Class of anesthetics

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    NMDA receptor antagonist

    NMDA receptor antagonist

    NMDA_receptor_antagonist

  • Liver X receptor
  • Nuclear receptor

    derivatives of cholesterol, such as 22(R)-hydroxycholesterol, 24(S)-hydroxycholesterol, 27-hydroxycholesterol, and cholestenoic acid, are the natural ligands

    Liver X receptor

    Liver X receptor

    Liver_X_receptor

  • Tropifexor
  • Chemical compound

    LXRTooltip Liver X receptor Agonists: 22R-Hydroxycholesterol 24S-Hydroxycholesterol 27-Hydroxycholesterol Abequolixron Cholestenoic acid DMHCA GW-3965

    Tropifexor

    Tropifexor

    Tropifexor

  • Androstenone
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Androstenone

    Androstenone

    Androstenone

  • Pentobarbital
  • Short-acting barbiturate

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Pentobarbital

    Pentobarbital

    Pentobarbital

  • Magnesium
  • Chemical element with atomic number 12 (Mg)

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Magnesium

    Magnesium

    Magnesium

  • Neurosteroid
  • Compounds that alter neuronal activity

    sulfate (DHEA-S; prasterone sulfate), and the cholestane 24(S)-hydroxycholesterol (NMDA receptor-selective; very potent). Pheromones are neurosteroids

    Neurosteroid

    Neurosteroid

    Neurosteroid

  • Acetylcysteine
  • Medication used to treat overdose of paracetamol

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Acetylcysteine

    Acetylcysteine

    Acetylcysteine

  • Zinc
  • Chemical element with atomic number 30 (Zn)

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Zinc

    Zinc

    Zinc

  • Phencyclidine
  • Dissociative hallucinogenic drug, mostly used recreationally

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Phencyclidine

    Phencyclidine

    Phencyclidine

  • Androstenetriol
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Androstenetriol

    Androstenetriol

    Androstenetriol

  • Ivermectin
  • Medication for parasite infestations

    LXRTooltip Liver X receptor Agonists: 22R-Hydroxycholesterol 24S-Hydroxycholesterol 27-Hydroxycholesterol Abequolixron Cholestenoic acid DMHCA GW-3965

    Ivermectin

    Ivermectin

    Ivermectin

  • 18-Hydroxycortisol
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    18-Hydroxycortisol

    18-Hydroxycortisol

    18-Hydroxycortisol

  • Phenobarbital
  • Medication of the barbiturate type

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Phenobarbital

    Phenobarbital

    Phenobarbital

  • Quercetin
  • Chemical compound

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Quercetin

    Quercetin

    Quercetin

  • Pregnenolone
  • Chemical compound

    intermediates in the transformation of cholesterol into pregnenolone, 22R-hydroxycholesterol and 20α,22R-dihydroxycholesterol, and all three steps in the transformation

    Pregnenolone

    Pregnenolone

    Pregnenolone

  • Steroid hormone
  • Substance with biological function

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Steroid hormone

    Steroid hormone

    Steroid_hormone

  • 11β-Hydroxytestosterone
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    11β-Hydroxytestosterone

    11β-Hydroxytestosterone

    11β-Hydroxytestosterone

  • Dihydrocortisone
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Dihydrocortisone

    Dihydrocortisone

    Dihydrocortisone

  • Mestranol/noretynodrel
  • Combined oral contraceptive medication

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Mestranol/noretynodrel

    Mestranol/noretynodrel

    Mestranol/noretynodrel

  • Progesterone
  • Sex hormone

    [citation needed] Cholesterol undergoes double oxidation to produce 22R-hydroxycholesterol and then 20α,22R-dihydroxycholesterol. This vicinal diol is then further

    Progesterone

    Progesterone

    Progesterone

  • XW10508
  • Experimental esketamine prodrug

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    XW10508

    XW10508

  • Dihydrotestosterone
  • Human hormone

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Dihydrotestosterone

    Dihydrotestosterone

    Dihydrotestosterone

  • 3-Chloro-PCP
  • Chemical compound

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    3-Chloro-PCP

    3-Chloro-PCP

    3-Chloro-PCP

  • Atrazine
  • Herbicide

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Atrazine

    Atrazine

    Atrazine

  • Atomoxetine
  • Medication used to treat ADHD

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Atomoxetine

    Atomoxetine

    Atomoxetine

  • Sevoflurane
  • Inhalational anaesthetic

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Sevoflurane

    Sevoflurane

    Sevoflurane

  • Pharmacokinetics of estradiol
  • 2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Pharmacokinetics of estradiol

    Pharmacokinetics of estradiol

    Pharmacokinetics_of_estradiol

  • Androgen
  • Any steroid hormone that promotes male characteristics

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Androgen

    Androgen

    Androgen

  • Cyclic glycine-proline
  • Small neuroactive peptide

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Cyclic glycine-proline

    Cyclic glycine-proline

    Cyclic_glycine-proline

  • 2F-NENDCK
  • Chemical compound

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    2F-NENDCK

    2F-NENDCK

    2F-NENDCK

  • Aspartic acid
  • Amino acid

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Aspartic acid

    Aspartic acid

    Aspartic_acid

  • Glutamic acid
  • Amino acid and neurotransmitter

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Glutamic acid

    Glutamic acid

    Glutamic_acid

  • Furosemide
  • Loop diuretic medication

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Furosemide

    Furosemide

    Furosemide

  • Soticlestat
  • Cholesterol 24-hydroxylase inhibitor

    enzyme in the brain that converts cholesterol to the oxysterol 24S-hydroxycholesterol (24S-HC). Reduction of 24S-HC has been shown to reduce glutamatergic

    Soticlestat

    Soticlestat

    Soticlestat

  • Diphenidine
  • Dissociative anesthetic designer drug

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Diphenidine

    Diphenidine

    Diphenidine

  • Clomifene
  • Infertility treatment for women

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Clomifene

    Clomifene

    Clomifene

  • 17β-Aminoestrogen
  • Class of chemical compounds

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    17β-Aminoestrogen

    17β-Aminoestrogen

    17β-Aminoestrogen

  • Glutamine
  • Amino acid

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Glutamine

    Glutamine

    Glutamine

  • Glutathione
  • Ubiquitous antioxidant compound in living organisms

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Glutathione

    Glutathione

    Glutathione

  • Amantadine
  • Medication used to treat dyskinesia

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Amantadine

    Amantadine

    Amantadine

  • Macrophage
  • Type of white blood cell

    been shown to be able to interact with Leydig cells by secreting 25-hydroxycholesterol, an oxysterol that can be converted to testosterone by neighbouring

    Macrophage

    Macrophage

    Macrophage

  • Nicotinamide
  • Vitamer of Vitamin B3

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Nicotinamide

    Nicotinamide

    Nicotinamide

  • 21-Deoxycortisone
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    21-Deoxycortisone

    21-Deoxycortisone

    21-Deoxycortisone

  • 1,1,1-Trichloroethane
  • Solvent, now banned for ozone depletion

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    1,1,1-Trichloroethane

    1,1,1-Trichloroethane

    1,1,1-Trichloroethane

  • 15α-Hydroxy-DHEA sulfate
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    15α-Hydroxy-DHEA sulfate

    15α-Hydroxy-DHEA sulfate

    15α-Hydroxy-DHEA_sulfate

  • Dehydroepiandrosterone
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    Dehydroepiandrosterone

    Dehydroepiandrosterone

    Dehydroepiandrosterone

  • Haloperidol
  • Typical antipsychotic medication

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Haloperidol

    Haloperidol

    Haloperidol

  • 16α-Hydroxyandrostenedione
  • Chemical compound

    v t e Endogenous steroids Precursors Cholesterol 22R-Hydroxycholesterol 20α,22R-Dihydroxycholesterol Pregnenolone 11β-Hydroxypregnenolone 17α-Hydroxypregnenolone

    16α-Hydroxyandrostenedione

    16α-Hydroxyandrostenedione

    16α-Hydroxyandrostenedione

  • Anethole
  • Chemical compound

    2-Phenylbenzofuran 2-Phenyl-1-benzothiophene 4'-Hydroxynorendoxifen 27-Hydroxycholesterol Acefluranol Acolbifene Afimoxifene Anordiol Anordrin Arzoxifene Bazedoxifene

    Anethole

    Anethole

    Anethole

  • Alanine
  • Α-amino acid that is used in the biosynthesis of proteins

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Alanine

    Alanine

    Alanine

  • Methoxyflurane
  • Volatile anaesthesia medication

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    Methoxyflurane

    Methoxyflurane

    Methoxyflurane

  • L-701324
  • NMDA receptor antagonist acting at the glycine site

    Neomycin Spermidine Spermine; Other positive allosteric modulators: 24S-Hydroxycholesterol DHEATooltip Dehydroepiandrosterone (prasterone) DHEA sulfate (prasterone

    L-701324

    L-701324

    L-701324

  • Fexaramine
  • Chemical compound

    LXRTooltip Liver X receptor Agonists: 22R-Hydroxycholesterol 24S-Hydroxycholesterol 27-Hydroxycholesterol Abequolixron Cholestenoic acid DMHCA GW-3965

    Fexaramine

    Fexaramine

    Fexaramine

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