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Excess uric acid in the blood
Hyperuricaemia or hyperuricemia is an abnormally high level of uric acid in the blood. In the pH conditions of body fluid, uric acid exists largely as
Hyperuricemia
Rare genetic disorder
disturbances including self-mutilation, and uric acid overproduction (hyperuricemia). Damage to the basal ganglia causes affected individuals to adopt a
Lesch–Nyhan_syndrome
Form of arthritis causing swollen joints
to persistently elevated levels of uric acid (urate) in the blood (hyperuricemia). This occurs from a combination of diet, other health problems, and
Gout
Organic compound
uric acid. Other factors possibly contributing to increased risk of hyperuricemia include alcohol consumption, obesity, male sex, and aging. In hominids
Uric_acid
Medical condition
insulin resistance, or prediabetes. Associated conditions include hyperuricemia; fatty liver (especially in concurrent obesity) progressing to nonalcoholic
Metabolic_syndrome
Croatian hunting/carriage/coach dog breed
suffer from hyperuricemia. Dalmatians' livers have trouble breaking down uric acid, which can build up in the blood serum (hyperuricemia) causing gout
Dalmatian_dog
Medication
Dotinurad (Urece) is a drug for the treatment of gout and hyperuricemia. It was developed by Fuji Yakuhin and approved for use in Japan in 2020, and in
Dotinurad
Loop diuretic medication
variation between individuals. Furosemide also can lead to gout caused by hyperuricemia. Hyperglycemia is also a common side effect. The tendency, as for all
Furosemide
Heterocyclic aromatic organic compound
60% of purines. A low-purine dietary plan that may reduce the risk of hyperuricemia and gout includes eggs, dairy products, fruits, vegetables, legumes
Purine
Chemical compound
acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively
Probenecid
Species of spore-bearing plant
often used as an herbal medicine, and has been used to treat gout and hyperuricemia. Lycopodioides tamariscina (P.Beauv.) H.S.Kung Lycopodium caulescens
Selaginella_tamariscina
Medical condition
high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi
Tophus
Substance that promotes the production of urine
hyperkalemia, hyponatremia, metabolic alkalosis, metabolic acidosis, and hyperuricemia. A common application of diuretics is for the purposes of invalidating
Diuretic
Medication
chemotherapeutic treatments, as these regimens can rapidly produce severe acute hyperuricemia; however, it has gradually been replaced by urate oxidase therapy. Intravenous
Allopurinol
Problematic excessive alcohol consumption
abnormalities including hypokalemia, hypomagnesemia, hyponatremia, hyperuricemia, metabolic acidosis, and respiratory alkalosis are common in people
Alcoholism
Pharmaceutical drug
of uric acid from other sources. For example, it has been used for hyperuricemia in gout, in other rheumatologic conditions, and in rhabdomyolysis with
Rasburicase
Medical condition
(hyperphosphatemia), low blood calcium (hypocalcemia), high blood uric acid (hyperuricemia), and higher than normal levels of blood urea nitrogen (BUN). These
Tumor_lysis_syndrome
Formation of mineral deposits in the kidneys
hyperuricosuria (an excessive amount of uric acid in the urine) with or without hyperuricemia (an excessive amount of uric acid in the serum). They may also form
Kidney_stone_disease
Sudden fatigue during endurance sports
the myokinase reaction and purine nucleotide cycle leads to myogenic hyperuricemia. In muscle glycogenoses (muscle GSDs), an inborn error of carbohydrate
Hitting_the_wall
Failure of cells to respond appropriately to insulin
clamp technique. Prognosis Hyperglycemia, hypertension, dyslipidemia, hyperuricemia, elevated inflammatory markers, endothelial dysfunction, a prothrombotic
Insulin_resistance
Excess uric acid in the urine
dissolution of uric acid crystals in the kidneys or urinary bladder, and hyperuricemia. Notable indirect causes include uricosuric drugs, rapid breakdown of
Hyperuricosuria
Chemical compound, medication to treat gout
sometimes referred to as FBX. Febuxostat is used to treat chronic gout and hyperuricemia. Febuxostat is typically recommended only for people who cannot tolerate
Febuxostat
Substance inhibiting xanthine oxidase
medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. Xanthine oxidase inhibitors
Xanthine_oxidase_inhibitor
Protein-coding gene in the species Homo sapiens
protein 8 is a protein that in humans is encoded by the GPATCH8 gene. Hyperuricemia cosegregating with osteogenesis imperfecta has been shown to be associated
GPATCH8
Buildup of metabolic waste due to kidney dysfunction
high amount of uric acid in blood, is a condition called hyperuricemia. Long-standing hyperuricemia can cause deposition of monosodium urate crystals in or
Protein_toxicity
Cholesterol-lowering medication
(high blood cholesterol levels). The most common side effects include hyperuricemia (high blood levels of uric acid), pain in arms or legs, and anemia (low
Bempedoic_acid
Medical condition
Kawachi, M.; Kiyokawa, H.; Wang, Y. L.; Tarui, S. (1987). "Myogenic hyperuricemia. A common pathophysiologic feature of glycogenosis types III, V, and
Glycogen_storage_disease
Medical condition
characterized by cranio-facial dysmorphisms and multiple skeletal anomalies. Hyperuricemia, hypertension and high erythrocyte sedimentation rates have also been
Familial osteodysplasia, Anderson type
Familial_osteodysplasia,_Anderson_type
Chemical compound
being developed by JW Pharmaceutical for the treatment of gout and hyperuricemia. It is a urate-lowering agent that selectively inhibits the human uric
Epaminurad
Meat-only human diet
S2CID 237343954. Li R, Yu K, Li C (2018). "Dietary factors and risk of gout and hyperuricemia: a meta-analysis and systematic review" (PDF). Asia Pacific Journal
Carnivore_diet
Exercise phenomenon
the myokinase reaction and purine nucleotide cycle leads to myogenic hyperuricemia. For McArdle disease (GSD-V), regular aerobic exercise utilizing "second
Second_wind
Human disease
same village, whose parents were not related. The acronym stands for Hyperuricemia, Pulmonary hypertension, Renal failure in infancy and Alkalosis. The
HUPRA_syndrome
Chemical compound
trade names Topiloric, Uriadec) is a drug for the treatment of gout and hyperuricemia. It was approved for use in Japan in June 2013. Topiroxostat is a xanthine
Topiroxostat
Species of tree
xanthine oxidase inhibitor, hence a potential drug for treatment of hyperuricemia and related medical conditions including gout. Cinnamomum osmophloeum
Cinnamomum_osmophloeum
Protein metabolic pathway
AMP buildup in muscle, and subsequent exercise-induced hyperuricemia (myogenic hyperuricemia) through conversion of excessive AMP into uric acid by way
Purine_nucleotide_cycle
Chemical compound
pub2. PMID 20091657. Figg WD (February 1990). "Cyclosporine-induced hyperuricemia and gout". The New England Journal of Medicine. 322 (5): 334–336. doi:10
Ciclosporin
Class of chemical compounds
blood. Hence, they are prescribed with caution in patients with gout or hyperuricemia. Chronic administration of thiazides is associated with the increase
Thiazide
Hypertension occurring during pregnancy
uric acid (hyperuricemia) to "define" pre-eclampsia, though it is a poor predictor of the disorder. Elevated levels in the blood (hyperuricemia) are likely
Pre-eclampsia
Long-term high blood pressure in the arteries
and is a component of syndrome X (or metabolic syndrome), can cause hyperuricemia and gout and is also associated with elevated blood pressure. Events
Hypertension
Drug of the fibrate class, mainly used to reduce cholesterol levels
systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia". Arthritis Care & Research. 64 (10): 1431–1446. doi:10.1002/acr.21772
Fenofibrate
Muscular diseases caused by defects in metabolic processes
(dyspnea/tachypnea/hyperpnea and tachycardia), Exercise-induced myogenic hyperuricemia (exercise-induced accelerated breakdown of purine nucleotides in muscle
Metabolic_myopathy
Pharmaceutical drug
common adverse reactions include pruritus, increased weight, rash, hyperuricemia, and upper respiratory tract infection. In April 2014, siltuximab was
Siltuximab
Poisoning caused by lead in the body
Sparrow D, Hu H (July 2000). "Effect of low level lead exposure on hyperuricemia and gout among middle aged and elderly men: the normative aging study"
Lead_poisoning
Medication mainly used to treat gout
systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia". Arthritis Care & Research. 64 (10): 1431–1446. doi:10.1002/acr.21772
Colchicine
Compound that inhibits the oxidation of other molecules
PMID 17910294. Campion EW, Glynn RJ, DeLabry LO (March 1987). "Asymptomatic hyperuricemia. Risks and consequences in the Normative Aging Study". The American
Antioxidant
Medical condition
feeding as a baby, hypoglycemia, jaundice, hemorrhage, hepatomegaly, hyperuricemia and potentially kidney failure. There are reported deaths in infants
Hereditary fructose intolerance
Hereditary_fructose_intolerance
Treatment for non-Hodgkin lymphoma
Allopurinol is typically co-administered prophylactically to prevent hyperuricemia that results from tumor lysis syndrome, the result of rapid death of
CHOP_(chemotherapy)
Combination drug
combination of bempedoic acid and ezetimibe. The most common side effects are hyperuricemia (high blood levels of uric acid) and constipation. Bempedoic acid is
Bempedoic_acid/ezetimibe
Abnormally elevated levels of lipids or lipoproteins in the blood
to chylomicrons. It is also associated with glucose intolerance and hyperuricemia. In medicine, combined hyperlipidemia (or -aemia) (also known as "multiple-type
Hyperlipidemia
Drug class
hyperuricosuria, but are contraindicated in persons with conditions including hyperuricemia and gout.[citation needed] Uricosuria Hamada T, Ichida K, Hosoyamada
Uricosuric
Class of therapeutic drug for relieving pain and inflammation
recommended owing to increased bleeding tendency. People with kidney disease, hyperuricemia, or gout should not take aspirin because it inhibits the ability of
Nonsteroidal anti-inflammatory drug
Nonsteroidal_anti-inflammatory_drug
Thiazide-like diuretic drug
with sub-clinical hyperparathyroidism are exposed to chlortalidone. Hyperuricemia, high levels of uric acid in the blood Hyperlipidemia, high cholesterol
Chlortalidone
Diuretic medication
magnesium), hyponatremia (low sodium), and hypercalcemia (high calcium) Hyperuricemia (high levels of uric acid in the blood). All thiazide diuretics including
Hydrochlorothiazide
Epidemiology of workplaces diseases
only the sample of workers with the disease to compare to a control. Hyperuricemia is a condition in which there are elevated levels of uric acid in the
Occupational_epidemiology
Lack of uric acid in the blood
women and less than 0.20 mmol/L in men.) Hyperuricemia Chizyński K, Rózycka M (November 2005). "[Hyperuricemia]". Pol. Merkur. Lekarski (in Polish). 19
Hypouricemia
Chemical compound
inhibitor, for the treatment of patients with gout and/or asymptomatic hyperuricemia in the United States and Japan: Findings from two phase II trials".
Verinurad
Aspartic protease protein and enzyme
(2009). "Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure". Am. J. Hum. Genet. 85 (2): 204–213
Renin
Body scale based on waist circumference and height
shape index for predicting the risk of hypertension, dyslipidemia, and hyperuricemia in Chinese women. Other indices of body and fat mass, such as BMI and
Body_roundness_index
Abnormal kidney structure or gradual loss of kidney function
but includes increased inflammation, reduction in erythropoietin, and hyperuricemia leading to bone marrow suppression. Hypoproliferative anemia occurs
Chronic_kidney_disease
Collective term for blood tests used to check the function of the thyroid
molecules Blood sugar level Hypoglycemia Hyperglycemia Nitrogenous Azotemia Hyperuricemia Hypouricemia Proteins LFT Elevated transaminases Elevated ALP Hypoproteinemia
Thyroid_function_tests
Class of chemically related vitamers
several grams per day. Other reactions include glucose intolerance, hyperuricemia, macular edema, and macular cysts. Niacin is incorporated into multi-vitamin
Vitamin_B3
Chemical compound
hypomagnesemia (low magnesium), hypercalcemia (high calcium), and hyperuricemia (high uric acid). These may result in dizziness, headache, or heart
Metolazone
Human disease caused by deficiency of a muscle enzyme
endocrine diseases (15.7%), musculoskeletal/rheumatic disease (12.9%), hyperuricemia/gout (11.6%), gastrointestinal diseases (11.2%), neurological disease
Glycogen storage disease type V
Glycogen_storage_disease_type_V
Medical condition
glucose-6-phosphatase are hypoglycemia, lactic acidosis, hypertriglyceridemia, and hyperuricemia. The hypoglycemia of GSD I is termed "fasting", or "post-absorptive"
Glycogen storage disease type I
Glycogen_storage_disease_type_I
American medical academic
Metabolism and in 1982, she published the book called The Kidney in Gout and Hyperuricemia . At age 81, Yu retired as the first female professor at Mount Sinai
Tsai-Fan_Yu
Diuretics that act along the loop of Henle in the kidneys
ADRs include: hyponatremia, hypokalemia, hypomagnesemia, dehydration, hyperuricemia, gout, dizziness, postural hypotension, syncope. The loss of magnesium
Loop_diuretic
in excess causes fatty liver disease). Pseudohypoxia also leads to hyperuricemia as elevated lactic acid inhibits uric acid secretion by the kidney;
Pseudohypoxia
Medication for constipation, classified as an osmotic laxative
2008). "PEG-uricase in the management of treatment-resistant gout and hyperuricemia". Advanced Drug Delivery Reviews. 60 (1): 59–68. doi:10.1016/j.addr
Macrogol
Mode of inheritance
disturbances including self-mutilation, and uric acid overproduction (hyperuricemia) Lowe syndrome; hydrophthalmia, cataracts, intellectual disabilities
X-linked recessive inheritance
X-linked_recessive_inheritance
One of the five major nucleosides in nucleic acids
51 (10): 1317–23. doi:10.1053/meta.2002.34041. PMID 12370853. "Gout, Hyperuricemia & Chronic Kidney Disease". The National Kidney Foundation. 24 December
Uridine
Discomfort following alcohol consumption
inhibition of the citric acid cycle, lactic acidosis, ketoacidosis, hyperuricemia, disturbance in cortisol and androgen metabolism and increased fibrogenesis
Hangover
Species of flowering plant in the plantain family Plantaginaceae
(Xanthine oxidase) significantly, and it can be used in the reduction of hyperuricemia and the treatment of gout. Plantamajoside can be isolated from Plantago
Plantago_asiatica
Protein-coding gene in the species Homo sapiens
transporter have been linked to increased risk of development of both hyperuricemia, gout and Alzheimer's disease. Glucose transporter Solute carrier family
SLC2A9
Pharmaceutical compound
Li R (November 2020). "The mechanism of Arhalofenate in alleviating hyperuricemia-Activating PPARγ thereby reducing caspase-1 activity". Drug Development
Arhalofenate
Medical condition
Metabolic Myopathies Exercise intolerance § low ATP reservoir Myogenic hyperuricemia Purine nucleotide cycle § pathology (low ATP reservoir, ADP>ATP, ↑AMP)
Inborn errors of carbohydrate metabolism
Inborn_errors_of_carbohydrate_metabolism
Chemical compound
resistance assessed by the homeostatic model assessment (HOMA-IR) method. Hyperuricemia or increased levels of serum uric acid have been reported with pitavastatin
Pitavastatin
Initially normal, then declining ability of a muscle to generate force
acquired) Fatigue Central fatigue Malaise Metabolic myopathy Myogenic hyperuricemia (due low ATP reservoir in muscle cell) Muscle weakness Paresis "Muscle
Muscle_fatigue
Combination drug
the US Food and Drug Administration approved it for the treatment of hyperuricemia associated with gout in patients for whom target serum uric acid levels
Lesinurad/allopurinol
Chemical reactions and pathways involving lysis of purine nucleotides
diseases are: Severe immunodeficiency by loss of adenosine deaminase. Hyperuricemia and Lesch–Nyhan syndrome by the loss of hypoxanthine-guanine phosphoribosyltransferase
Purine_metabolism
Chemical compound
Jiménez RT, Puig JG (2012). "Purine Metabolism in the Pathogenesis of Hyperuricemia and Inborn Errors of Purine Metabolism Associated With Disease". Gout
Ribose_5-phosphate
Pharmaceutical drug for the treatment of gout
oxidase inhibitor, such as allopurinol or febuxostat, for treating hyperuricemia (high levels of uric acid in the blood serum) associated with gout.
Lesinurad
Medical condition
uric acid crystals in the joints because of high acidity of the blood (hyperuricemia). Cadmium exposure is also associated with the development of kidney
Cadmium_poisoning
Chemical compound
which is being discussed as an active ingredient for the treatment of hyperuricemia and gout. 3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) has gained greater
5-Nitrovanillin
Chemical compound
Benzbromarone is primarily indicated for the long-term management of hyperuricemia and chronic gout, especially when first-line treatments like allopurinol
Benzbromarone
Human chromosome
doi:10.1089/gte.1997.1.145. PMID 10464639. "OMIM Entry - # 613845 - HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME; HUPRAS"
Chromosome_19
Class of pharmaceuticals
Research Reviews. 23 (2): 146–89. doi:10.1002/med.10025. PMID 12500287. Hyperuricemia Medication~medication at eMedicine Greger, Rainer; Windhorst, Uwe (1996)
Carbonic_anhydrase_inhibitor
Pharmaceutical drug
elevated blood pressure (hypertension) and elevated uric acid levels (hyperuricemia). There was also an increased risk of thrombosis (blood clots) in patients
Luspatercept
Mammalian protein found in Homo sapiens
nephropathy (FJHN)). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive kidney failure. Antibodies to Tamm–Horsfall protein
Uromodulin
Herring roe
dieteary cautions and recommendations apply to those diagnosed with hyperuricemia, which is considered a preliminary stage towards gout. In Japan, the
Kazunoko
Chemical compound
and Xanthine Oxidase Inhibitor, Febuxostat, in Patients With Primary Hyperuricemia". The Journal of Clinical Pharmacology. 63 (2): 239–249. doi:10.1002/jcph
Ruzinurad
Metabolism of fructose
abdominal pain, vomiting, hemorrhage, jaundice, hepatomegaly, and hyperuricemia eventually leading to liver and/or kidney failure and death. The incidence
Fructolysis
Protein-coding gene in the species Homo sapiens
gene set have been shown to cause a collection of diseases, such as hyperuricemia, metabolic alkalosis, pulmonary hypertension, and progressive kidney
SARS_(gene)
Enzyme that converts hypoxanthine to inosine monophosphate
Leishmania HGPRT and validates the result. Mutations in the gene lead to hyperuricemia. At least 67 disease-causing mutations in this gene have been discovered:
Hypoxanthine-guanine phosphoribosyltransferase
Hypoxanthine-guanine_phosphoribosyltransferase
Type of beverage
Atalay, Huseyin (October 2010). "Sugar-sweetened soda consumption, hyperuricemia, and kidney disease". Kidney International. 78 (7): 708, author reply
Sweetened_beverage
Chemical compound
the blood. The body may react to this. Signs include hyperkalemia, hyperuricemia, and hyperphosphatemia. TLS is very serious and can lead to death if
Clofarabine
Chemical compound
characterized by the overproduction and accumulation of uric acid leading to hyperuricemia and hyperuricosuria. It is one of the causes of gout. Increased levels
Phosphoribosyl_pyrophosphate
Antibiotic against tuberculosis
transaminases, and pyuria. Overdoses have been associated with hematuria and hyperuricemia. Rifapentine in pregnant women has not been studied, but animal reproduction
Rifapentine
English judge and vegetarian (1821–1894)
& was married. Hannen had a bladder stone removed and suffered from hyperuricemia. He was advised by his surgeon to take up a vegetarian diet which he
James_Hannen,_Baron_Hannen
dysplasia short stature Deafness goiter stippled epiphyses Deafness hyperuricemia neurologic ataxia Deafness hypogonadism syndrome Deafness hypospadias
List_of_diseases_(D)
Metabolic enzyme
leave the muscle cell to be converted into uric acid, known as myogenic hyperuricemia. AMP → IMP → Inosine → Hypoxanthine → Xanthine → Uric acid. Unfortunately
Phosphoglucomutase
HYPERURICEMIA
HYPERURICEMIA
HYPERURICEMIA
HYPERURICEMIA
Boy/Male
Arabic
Friend of God
Girl/Female
Tamil
Small, Intelligent and cautious
Girl/Female
Arabic, Indian, Islamic, Kashmiri, Muslim, Urdu
Beautiful
Boy/Male
Gujarati, Hindu, Indian, Kannada
One who does Good Deeds
Boy/Male
Polish
Glory and honour.
Girl/Female
Indian
Adorned with intellect
Girl/Female
Bengali, Hindu, Indian
An Princess; An Enchantress
Girl/Female
Muslim
Butterfly
Girl/Female
Hindu, Indian
Goddess
Surname or Lastname
English
English : from a diminutive of Clare or Clark.
HYPERURICEMIA
HYPERURICEMIA
HYPERURICEMIA
HYPERURICEMIA
HYPERURICEMIA