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MAJOR HISTOCOMPATIBILITY-COMPLEX-CLASS-II-DQ-ALPHA-1

  • Major histocompatibility complex, class II, DQ alpha 1
  • Protein-coding gene in the species Homo sapiens

    Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also

    Major histocompatibility complex, class II, DQ alpha 1

    Major histocompatibility complex, class II, DQ alpha 1

    Major_histocompatibility_complex,_class_II,_DQ_alpha_1

  • Major histocompatibility complex
  • Cell surface proteins, part of the adaptive immune system

    The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface

    Major histocompatibility complex

    Major histocompatibility complex

    Major_histocompatibility_complex

  • MHC class II
  • Protein of the immune system

    MHC Class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such

    MHC class II

    MHC class II

    MHC_class_II

  • List of A1 genes, proteins or receptors
  • alpha 1 Major histocompatibility complex, class II, DQ alpha 1 Myosin light chain A1, an actin-binding protein NADH dehydrogenase (ubiquinone), alpha

    List of A1 genes, proteins or receptors

    List_of_A1_genes,_proteins_or_receptors

  • HLA-DQ
  • Cell surface receptor protein found on antigen-presenting cells

    HLA-DQ (DQ) is a cell surface receptor protein found on antigen-presenting cells. It is an αβ heterodimer of type MHC class II. The α and β chains are

    HLA-DQ

    HLA-DQ

    HLA-DQ

  • Human leukocyte antigen
  • Genes on human chromosome 6

    The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many other animals. Specific HLA genes may be

    Human leukocyte antigen

    Human leukocyte antigen

    Human_leukocyte_antigen

  • HLA-DQB1
  • Protein-coding gene in the species Homo sapiens

    Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene

    HLA-DQB1

    HLA-DQB1

    HLA-DQB1

  • HLA-DR1
  • Serotype of cell surface receptors

    structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule". J. Biol. Chem. 281 (35): 25356–25364

    HLA-DR1

    HLA-DR1

    HLA-DR1

  • HLA-DQ7
  • Marcus-Bagley D, Good RA, Ahmed AR (August 1994). "Common major histocompatibility complex class II markers in clinical variants of cicatricial pemphigoid"

    HLA-DQ7

    HLA-DQ7

    HLA-DQ7

  • HLA-DQA2
  • Protein-coding gene in the species Homo sapiens

    HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23

    HLA-DQA2

    HLA-DQA2

    HLA-DQA2

  • HLA-DR
  • Subclass of HLA-D antigens that consist of alpha and beta chains

    immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules". Proc. Natl. Acad. Sci. U.S.A. 87 (22): 9052–6

    HLA-DR

    HLA-DR

    HLA-DR

  • MiR-137
  • RNA family

    (open reading frame of chromosome 6), HLA-DQA1 (Major histocompatibility complex, class II, DQ alpha 1), TNXB (A member of the tenascin family, also known

    MiR-137

    MiR-137

    MiR-137

  • HLA-DRB4
  • Protein-coding gene in the species Homo sapiens

    Major histocompatibility complex, class II, DR beta 4, also known as HLA-DRB4, is a human gene. The protein encoded by this gene belongs to the HLA class

    HLA-DRB4

    HLA-DRB4

    HLA-DRB4

  • Chromosome 6
  • Human chromosome

    represents 5.5–6% of the total DNA in cells. It contains the major histocompatibility complex, which contains over 132 genes related to the immune response

    Chromosome 6

    Chromosome 6

    Chromosome_6

  • HLA-DQ1
  • Serotype that covers a broad range of HLA-DQ haplotypes

    serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1; later, it was among 3 types

    HLA-DQ1

    HLA-DQ1

    HLA-DQ1

  • HLA-DPB1
  • Protein-coding gene in the species Homo sapiens

    class II histocompatibility antigen, DP(W2) beta chain is a protein that in humans is encoded by the HLA-DPB1 gene. HLA-DPB belongs to the HLA class II

    HLA-DPB1

    HLA-DPB1

    HLA-DPB1

  • Superantigen
  • Antigen which strongly activates the immune system

    domain. The domains have binding regions for the major histocompatibility complex class II (MHC class II) and the T-cell receptor (TCR), respectively. By

    Superantigen

    Superantigen

    Superantigen

  • HLA-DR3
  • McDonnell S, Schaid D, Moore S, Rodriguez M (1998). "Major histocompatibility complex class II alleles and the course and outcome of MS: a population-based

    HLA-DR3

    HLA-DR3

    HLA-DR3

  • HLA-DR4
  • Molecule triggering an immune response

    "Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans". Tissue Antigens. 41 (2): 57–64

    HLA-DR4

    HLA-DR4

    HLA-DR4

  • HLA A1-B8-DR3-DQ2
  • Human genotype

    1, COX, Super B8, ancestral MHC 8.1 or 8.1 ancestral haplotype) is a multigene haplotype that covers a majority of the human major histocompatibility

    HLA A1-B8-DR3-DQ2

    HLA_A1-B8-DR3-DQ2

  • Anti-SSA/Ro autoantibodies
  • Type of anti-nuclear autoantibodies

    photosensitivity. Certain alleles of the human major histocompatibility complex (MHC II, called HLA II in humans) have been associated with the presence

    Anti-SSA/Ro autoantibodies

    Anti-SSA/Ro autoantibodies

    Anti-SSA/Ro_autoantibodies

  • HLA-DQB2
  • Protein-coding gene in the species Homo sapiens

    Servenius B, et al. (1987). "Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes". J. Biol. Chem

    HLA-DQB2

    HLA-DQB2

    HLA-DQB2

  • HLA-DQ8
  • Human leukocyte antigen serotype, associated with coeliac disease

    Goto K, Ota M, Geng Z, Geng L, Li G, Inoko H (1998). "Major histocompatibility complex class II alleles in an Uygur population in the Silk Route of Northwest

    HLA-DQ8

    HLA-DQ8

    HLA-DQ8

  • HLA-DR53
  • Howard A, Awdeh Z, Alper C, Yunis E (1995). "The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced

    HLA-DR53

    HLA-DR53

    HLA-DR53

  • HLA-DQ2
  • Human leukocyte antigen serotype

    McDonnell S, Schaid D, Moore S, Rodriguez M (1998). "Major histocompatibility complex class II alleles and the course and outcome of MS: a population-based

    HLA-DQ2

    HLA-DQ2

    HLA-DQ2

  • HLA-DQ5
  • Human leukocyte antigen serotype

    "Investigation of the association of major histocompatibility complex genes, including HLA class I, class II and TAP genes, with clinical forms of Crohn's

    HLA-DQ5

    HLA-DQ5

    HLA-DQ5

  • History and naming of human leukocyte antigens
  • Classification of leukocyte antigens

    encoded MHC class II. Several renamings occurred. The D-region has 8 major coding loci that combine to form 3 different protein groups; DP, DQ, and DR. DRw

    History and naming of human leukocyte antigens

    History_and_naming_of_human_leukocyte_antigens

  • HLA-DOA
  • Protein-coding gene in the species Homo sapiens

    class II histocompatibility antigen, DO alpha chain is a protein that in humans is encoded by the HLA-DOA gene. HLA-DOA belongs to the HLA class II alpha

    HLA-DOA

    HLA-DOA

    HLA-DOA

  • HLA B7-DR15-DQ6
  • a multigene haplotype that covers a majority of the human major histocompatibility complex on chromosome 6. A multigene haplotype is set of inherited

    HLA B7-DR15-DQ6

    HLA_B7-DR15-DQ6

  • HLA-DR16
  • haplotypes and microsatellite polymorphisms in and around the major histocompatibility complex region in a Native American population with a high prevalence

    HLA-DR16

    HLA-DR16

    HLA-DR16

  • HLA-DQ3
  • molecules differ markedly in function, even when present with the same DQ alpha subunit. For this reason they are best treated independently. The serotyping

    HLA-DQ3

    HLA-DQ3

    HLA-DQ3

  • HLA-DR7
  • DR7-DQ2/DR5-DQ7 phenotype (transhaplotype encoded isoform DQα5β2) is the primary risk DQ isoform in celiac disease. DR7-DQ2/DR5-DQ7 (/DR11-DQ7 or /DR12-DQ7) is a clarifying

    HLA-DR7

    HLA-DR7

    HLA-DR7

  • HLA-DR15
  • HLA-DR serotype

    N, Souza P, Franco E, Villa L, Petzl-Erler M (2000). "Major histocompatibility complex class II polymorphisms and risk of cervical cancer and human papillomavirus

    HLA-DR15

    HLA-DR15

    HLA-DR15

  • Outline of immunology
  • Overview of and topical guide to immunology

    (G-CSF) Major histocompatibility complex MHC class I HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G MHC class II HLA-DM α β HLA-DO α β HLA-DP α1 β1 HLA-DQ α1 α2 β1

    Outline of immunology

    Outline_of_immunology

  • Apolipoprotein M
  • Protein-coding gene in the species Homo sapiens

    S, et al. (December 2003). "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse". Genome Research

    Apolipoprotein M

    Apolipoprotein M

    Apolipoprotein_M

  • HLA-DR51
  • Martin R (2006). "Redundancy in antigen-presenting function of the HLA-DR and -DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotype". J Immunol

    HLA-DR51

    HLA-DR51

    HLA-DR51

  • HLA-DR52
  • Forcione D, Finkelstein D, Podolsky DK, Pillai S (1998). "Analysis of MHC class II DP, DQ and DR alleles in Crohn's disease". Gut. 43 (2): 210–5. doi:10.1136/gut

    HLA-DR52

    HLA-DR52

    HLA-DR52

  • HLA-DR12
  • Havelka S, Ivaskova E, Stastny P (1994). "Class II alleles in juvenile arthritis in Czech children". J Rheumatol. 21 (1): 159–64. PMID 8151573. Vargas-Alarcon

    HLA-DR12

    HLA-DR12

    HLA-DR12

  • Severe cutaneous adverse reactions
  • Group of adverse drug reactions involving the skin and mucosa

    are inserted into a groove on HLA proteins that are part of major histocompatibility complexes (i.e. MHC) and presented to T-cell receptors (TCR) on nearby

    Severe cutaneous adverse reactions

    Severe_cutaneous_adverse_reactions

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