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Disease that damages the myelin sheaths around nerves
Multiple sclerosis (MS) is an autoimmune disease where the immune system attacks myelin, the insulating cover of nerve cells in the human body, causing
Multiple_sclerosis
Atypical multiple sclerosis lesions
Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics
Tumefactive multiple sclerosis
Tumefactive_multiple_sclerosis
Approaches to managing the disease
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS). Several therapies for it exist,
Management of multiple sclerosis
Management_of_multiple_sclerosis
Current standards for diagnosing multiple sclerosis (MS) are based on the 2018 revision of McDonald criteria. They rely on MRI detection (or clinical demonstration)
Diagnosis of multiple sclerosis
Diagnosis_of_multiple_sclerosis
Topics referred to by the same term
Multiple Sclerosis Society may refer to: The Multiple Sclerosis Society of Great Britain The Multiple Sclerosis Society of Canada The National Multiple
Multiple_Sclerosis_Society
Neurological signs and symptoms
Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia)
Signs and symptoms of multiple sclerosis
Signs_and_symptoms_of_multiple_sclerosis
American nonprofit organization
The National Multiple Sclerosis Society (NMSS) is an American nonprofit organization founded in 1946. It is dedicated to supporting individuals affected
National Multiple Sclerosis Society
National_Multiple_Sclerosis_Society
Medical condition
acute multiple sclerosis, also known as Marburg multiple sclerosis or acute fulminant multiple sclerosis, is considered one of the multiple sclerosis borderline
Marburg acute multiple sclerosis
Marburg_acute_multiple_sclerosis
This is a list of notable people with multiple sclerosis. Multiple sclerosis is a demyelinating disease in which the insulating covers of nerve cells in
List of people with multiple sclerosis
List_of_people_with_multiple_sclerosis
Pathologic overview
Multiple sclerosis (MS) can be pathologically defined as the presence of distributed glial scars (scleroses) in the central nervous system that must show
Pathology of multiple sclerosis
Pathology_of_multiple_sclerosis
Disease pathology and physiology
Multiple sclerosis is an inflammatory demyelinating disease of the CNS in which activated immune cells invade the central nervous system and cause inflammation
Pathophysiology of multiple sclerosis
Pathophysiology_of_multiple_sclerosis
Research in multiple sclerosis may find new pathways to interact with the disease, improve function, curtail attacks, or limit the progression of the underlying
Research in multiple sclerosis
Research_in_multiple_sclerosis
Several biomarkers for diagnosis of multiple sclerosis, disease evolution and response to medication (current or expected) are under research. While most
Biomarkers of multiple sclerosis
Biomarkers_of_multiple_sclerosis
Australian non-profit organization
Multiple Sclerosis Australia, or MS Australia, is a national non-profit organization in Australia that coordinates and allocates funds for multiple sclerosis
Multiple_Sclerosis_Australia
Stiffening of a tissue or anatomical feature
disease that most often affects the vulva and the penis. Multiple sclerosis, or focal sclerosis, is a central nervous system disease which affects coordination
Sclerosis_(medicine)
Overview article
There are several ways for pharmaceuticals for treating multiple sclerosis (MS) to reach the market. Novel pharmaceuticals cannot enter the US market without
Multiple sclerosis drug pipeline
Multiple_sclerosis_drug_pipeline
MS Focus: The Multiple Sclerosis Foundation, also known as the Multiple Sclerosis Foundation or just MS Focus, is a 501(c)(3) non-profit organization
Multiple_Sclerosis_Foundation
Research in Multiple Sclerosis (ECTRIMS) Patient Advocacy Organization: Multiple Sclerosis International Federation European Multiple Sclerosis Platform
List of multiple sclerosis organizations
List_of_multiple_sclerosis_organizations
Human disease
often grouped together under Multiple Sclerosis. They are sometimes considered different diseases from Multiple Sclerosis, but considered by others to
Inflammatory demyelinating diseases of the central nervous system
Inflammatory_demyelinating_diseases_of_the_central_nervous_system
The Multiple Sclerosis International Federation (MSIF) was established in 1967 as an international body linking the activities of various national MS societies
Multiple Sclerosis International Federation
Multiple_Sclerosis_International_Federation
Rare neurodegenerative disease
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a rare terminal neurodegenerative disease defined
ALS
Australian doctor
evaluates modifiable risk factors that predict the progression of Multiple sclerosis. He has served since 2017 as the Chief Editor for Neuroepidemiology
George_Jelinek
Episodes of uncontrollable crying or laughing
attention deficit hyperactivity disorder (ADHD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD). It has been
Pseudobulbar_affect
Academic journal
The Multiple Sclerosis Journal (formerly Multiple Sclerosis) is a monthly peer-reviewed medical journal covering the clinical neurology of multiple sclerosis
Multiple_Sclerosis_Journal
Medical condition
similar to aggressive forms of multiple sclerosis. Although historically considered rare, with fewer than 1% of multiple sclerosis cases showing the characteristic
Baló_concentric_sclerosis
Significant disability caused by MS
Malignant multiple sclerosis is used to describe MS patients who reach significant level of disability in a short period of time. Malignant MS cases are
Malignant_multiple_sclerosis
Marker in blood/cerebrospinal fluid testing
in the CSF of more than 95% of patients with clinically definite multiple sclerosis. Two methods of analysis are possible: (a) protein electrophoresis
Oligoclonal_band
American neurologist and neuroimmunologist (born c. 1956)
in St. Louis School of Medicine and co-directs the John L Trotter Multiple Sclerosis Clinic at Barnes-Jewish Hospital. Cross is a leader in the field of
Anne_Haney_Cross
Pharmaceutical drug
treatment of adults with highly active forms of relapsing-remitting multiple sclerosis. Cladribine is a purine analogue that selectively targets and suppresses
Cladribine
British health charity
The Multiple Sclerosis Trust (MS Trust) is an independent, national UK charity that was established in 1993. The MS Trust works to provide information
Multiple_Sclerosis_Trust
Central nervous system disease
include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies
Neurodegenerative_disease
Medication used to treat multiple sclerosis and Crohn's disease
the brand name Tysabri among others, is a medication used to treat multiple sclerosis and Crohn's disease. It is a humanized monoclonal antibody against
Natalizumab
Multiple Sclerosis Discovery Forum (MSDF) is a non-profit online resource created to speed progress toward a cure for multiple sclerosis (MS) and other
Multiple Sclerosis Discovery Forum
Multiple_Sclerosis_Discovery_Forum
Disorders of adaptive immune system
bowel diseases (such as Crohn's disease and ulcerative colitis), multiple sclerosis, alopecia areata, Addison's disease, pernicious anemia, psoriasis
Autoimmune_disease
Pseudoscientific alternative medical therapy using bee products
including several types of arthritis; neurological problems such as multiple sclerosis, lower back pain and migraine headaches; and skin conditions such
Apitherapy
Wakefulness-promoting medication
common and often debilitating symptom experienced by people with multiple sclerosis. Reviews and meta-analyses of controlled trials have found that modafinil
Modafinil
The Multiple Sclerosis Functional Composite (MSFC) is a clinical trial outcome measure of assessing the severity of multiple sclerosis primarily used in
Multiple sclerosis functional composite
Multiple_sclerosis_functional_composite
American actor (1947–2020)
Laverne & Shirley. He served as a goodwill ambassador for the National Multiple Sclerosis Society. David Leonard Landau was born on June 22, 1947, in Brooklyn
David_Lander
Medical diagnostic method
(PASAT). The subjects are given in the version used as part of the Multiple Sclerosis Functional Composite a number every 3 seconds and are asked to add
Paced Auditory Serial Addition Test
Paced_Auditory_Serial_Addition_Test
Neuropsychiatrist
neuropsychiatrist. His research and clinical work focuses on people with multiple sclerosis, traumatic brain injury and Conversion Disorder. He has undertaken
Anthony_Feinstein
Dutch mystic (1380-1433)
nose. Today, some posit that Saint Lidwina is one of the first known multiple sclerosis patients and attribute her disability to the effects of the disease
Lidwina
Worsening of neurologic symptoms in multiple sclerosis caused by heat
and Uhthoff's symptom) is the worsening of neurologic symptoms in multiple sclerosis (MS) and other demyelinating diseases when the body is overheated
Uhthoff's_phenomenon
Spanish athlete
with multiple sclerosis, with an extraordinary story of personal improvement, which was made into a film in 2016. After he was diagnosed with multiple sclerosis
Ramón_Arroyo_(athlete)
Pediatric neurologist and academic
University of Pennsylvania. Banwell is the co-director of the Pediatric Multiple Sclerosis and Neuroinflammatory Disorders Clinic at the Children's Hospital
Brenda_Banwell
Reversal of sleeping tendencies
patients' circadian rhythm. In neuroinflammatory conditions such as Multiple Sclerosis, sleep inversion arises due to alterations in sleep architecture,
Sleep_inversion
Class of immunosuppressive drug
a TNF-alpha inhibitor prototype, Lenercept, for the treatment of multiple sclerosis (MS). However, the patients in the study who received the drug had
TNF_inhibitor
vitamin D can result in "growth retardation and skeletal deformities." Multiple sclerosis (MS) is least prevalent in the sunniest regions. According to a study
Health effects of sunlight exposure
Health_effects_of_sunlight_exposure
Intense feelings of well-being
following the migraine episode. Euphoria sometimes occurs in persons with multiple sclerosis as the illness progresses. This euphoria is part of a syndrome originally
Euphoria
Protein-coding gene in the species Homo sapiens
Certain HLA-DQB1 alleles are also linked to a modest increased risk of multiple sclerosis. Other HLA-DQB1 alleles are associated with a predisposition to narcolepsy
HLA-DQB1
Disorder impairing normal brain function
because of years of misdiagnosis and accusations of malingering. Multiple sclerosis has some overlapping symptoms with FNSD, potentially a source of misdiagnosis
Functional neurological symptom disorder
Functional_neurological_symptom_disorder
known as the "Multiple Sclerosis Fashionista." Murray was born in Paddington, London. In 2014, Murray was diagnosed with multiple sclerosis (MS) whilst
Roxy_Murray
American actress (born 1981)
2018. In January 2016, Sigler revealed that she was diagnosed with multiple sclerosis (MS) when she was 20 years old. In 2000, while filming Campfire Stories
Jamie-Lynn_Sigler
Virus of the herpes family
active US military over 20 years suggested EBV as the leading cause of multiple sclerosis (MS), with a recent EBV infection causing a 32-fold increase in MS
Epstein–Barr_virus
American pharmaceutical company
beta-1a (Plegridy), and natalizumab (Tysabri), all for the treatment of multiple sclerosis (collectively 45% of 2024 revenues); nusinersen (Spinraza) for the
Biogen
Acute inflammation diseases of the optic nerve and spinal cord
formal loss of visual acuity. Compared to idiopathic ON and ON due to multiple sclerosis (MS), ON due to NMOSD more often results in severe visual loss at
Neuromyelitis optica spectrum disorder
Neuromyelitis_optica_spectrum_disorder
Hematologist, clinician-scientist
pioneering work on hematopoietic stem cell transplantation (HSCT) for multiple sclerosis (MS) and other severe autoimmune diseases. Based at Careggi University
Riccardo_Saccardi
Inflammation of nervous tissue
lateral sclerosis". Journal of Neuroimmunology. 235 (1–2): 104–109. doi:10.1016/j.jneuroim.2011.03.011. PMID 21501881. S2CID 30757392. "Multiple Sclerosis: Hope
Neuroinflammation
Medical specialty that focuses on the design and application of orthoses
system (e.g. cerebral palsy, traumatic brain injury, stroke, and multiple sclerosis) can cause incorrect motor impulses that often result in clearly visible
Orthotics
Natural partial recreation of myelin sheaths in the brain
the hope of finding treatments for demyelinating diseases, such as multiple sclerosis. As of 2022 the status of possible remyelination acceleration is of
Remyelination
Medical condition
optica (NMO), Balo concentric sclerosis and Marburg multiple sclerosis. Symptoms are similar to those in multiple sclerosis and may include dementia, aphasia
Diffuse myelinoclastic sclerosis
Diffuse_myelinoclastic_sclerosis
American football player (born 2003)
National Multiple Sclerosis Society, and his mother, Elsa, lives with multiple sclerosis. Mendoza, alongside his brother, has created multiple menu items
Fernando_Mendoza
Artificial miniature brain like organ
insight into dysregulation of genes responsible for tumor development. Multiple sclerosis is an auto-immune inflammatory disorder affecting the central nervous
Cerebral_organoid
Clinical situation indicative of possible multiple sclerosis
situation in which a person has white matter lesions suggestive of multiple sclerosis (MS), as shown on an MRI scan that was done for reasons unrelated
Radiologically isolated syndrome (multiple sclerosis)
Radiologically_isolated_syndrome_(multiple_sclerosis)
2024 American film by Ron Howard
focuses on writing his manifesto, while Dore resolves to cure her multiple sclerosis through meditation. Their solitude, however, is short-lived. They
Eden_(2024_film)
British neurologist (1890–1981)
multiple sclerosis. His book Multiple sclerosis, published first time in 1955, has since his death been published with the title McAlpine's Multiple Sclerosis
Douglas_McAlpine
American author and philanthropist (born 1949)
presidential campaigns in 2008 and in 2012. Romney was diagnosed with multiple sclerosis in 1998. She has credited a mixture of mainstream and alternative
Ann_Romney
Chemical compound and essential nutrient
health, and as 300 mg per day as a possibly effective treatment for multiple sclerosis (see § Research). Overconsumption of 5 mg/day or higher causes elevated
Biotin
Human disease involving inability to control defecation
constipation. It is common in people with spinal cord injury (SCI), multiple sclerosis (MS) or spina bifida. The gastrointestinal tract (GI tract) has a
Neurogenic_bowel_dysfunction
Organic chemical that functions both as a hormone and a neurotransmitter
that dopamine imbalance influences the fatigue in multiple sclerosis. In patients with multiple sclerosis, dopamine inhibits production of IL-17 and IFN-γ
Dopamine
State of tiredness, exhaustion or loss of energy
[citation needed] autoimmune diseases, such as celiac disease, lupus, multiple sclerosis, myasthenia gravis, NMOSD, Sjögren's syndrome, rheumatoid arthritis
Fatigue
Pain affecting the somatosensory nervous system
underlying conditions such as primary presentation of a tumor or multiple sclerosis. Quantitative sensory testing (QST), a system of detailed analysis
Neuropathic_pain
Dizziness with sensation of moving or surrounding objects moving
neuritis. Less common causes include stroke, brain tumors, brain injury, multiple sclerosis, migraines, trauma, and uneven pressures between the middle ears.
Vertigo
American actress (1944–2024)
(1997–98). In 2002, Garr announced that she had been diagnosed with multiple sclerosis, the symptoms of which had affected her ability to perform. She retired
Teri_Garr
Chemical compound
It has also been used as a drug, to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults
4-Aminopyridine
Inflammation of the optic nerve
ON and "atypical" ON. The most commonly considered etiologies are multiple sclerosis (MS), neuromyelitis optica (NMO) / neuromyelitis optica spectrum disorder
Optic_neuritis
First Lady of Maryland since 2023
and First Family in Annapolis, Maryland. Moore was diagnosed with multiple sclerosis (MS) in her late twenties. She controlled the disease with medication
Dawn_Moore
Cellular response to brain injury involving glial cells
multiple system atrophy, prion disease, multiple sclerosis, AIDS dementia complex, vasculitis, Parkinson's disease, amyotrophic lateral sclerosis, and
Gliosis
American actress (born 1972)
projects like Legally Blonde and Hellboy. After being diagnosed with multiple sclerosis (MS) in 2018, she has shared her experience with the condition, contributing
Selma_Blair
American actress (born 1958)
from a prominent family in Costa Rica. Stowe's father suffered from multiple sclerosis, and she accompanied him to all his medical treatments. Stowe began
Madeleine_Stowe
Anti-CD20 monoclonal antibody
the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis. It is a humanized anti-CD20 monoclonal antibody. It targets CD20
Ocrelizumab
Pharmaceutical compound
GM-CSF has been shown to be involved in autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) in which cases GM-CSF levels are
Otilimab
neurodegenerative diseases, particularly multiple sclerosis, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). His work extensively utilizes longitudinal
Alberto_Ascherio
Chemical compound
Tolebrutinib is an investigational new drug that is being evaluated to treat multiple sclerosis. It is a Bruton's tyrosine kinase inhibitor. In April 2026, the Committee
Tolebrutinib
Species of virus
virally induced paralysis, as well as encephalomyelitis comparable to multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range
Theiler's murine encephalomyelitis virus
Theiler's_murine_encephalomyelitis_virus
Organic compound involved in immune responses
production.[medical citation needed] Histamine therapy for treatment of multiple sclerosis was being studied as of 2010[update]. The different H receptors have
Histamine
Effects of vitamin D on the nervous system
neuropsychiatric disorders, including Alzheimer's disease, autism, epilepsy, multiple sclerosis, Parkinson's disease, and schizophrenia. Vitamin D (the inactive version)
Vitamin_D_and_neurology
Medical procedure to replace blood or immune stem cells
deficiency syndromes Autoimmune diseases, including multiple sclerosis Many recipients of HSCTs are multiple myeloma or leukemia patients who would not benefit
Hematopoietic stem cell transplantation
Hematopoietic_stem_cell_transplantation
American actress
she was a vegan. According to her mother, Cybill Shepherd, Ford has multiple sclerosis. In 2000, Ford married Canadian actor Chad Todhunter. They divorced
Clementine_Ford
Inflammation of the entire cross-section of the spinal cord
autoimmunity, and when it appears in multiple sclerosis (MS) cases, it's often misdiagnosed as multiple sclerosis (MS) or seen as a type of MS. But NMO
Transverse_myelitis
English television presenter (1957–2024)
young carer at the age of 8; after his mother was diagnosed with multiple sclerosis, he learned to cook to help his family. He attended Barrow-in-Furness
Dave_Myers_(presenter)
Collection of molecular regulators
artificial neural networks with a hidden layer. There are three classes of multiple sclerosis: relapsing-remitting (RRMS), primary progressive (PPMS) and secondary
Gene_regulatory_network
self-administered, targeted B-cell therapy for patients with relapsing multiple sclerosis" (Press release). Novartis. 20 August 2020. Archived from the original
List of therapeutic monoclonal antibodies
List_of_therapeutic_monoclonal_antibodies
Psychoactive component of cannabis
botanical drug which contains THC, is used medically to treat symptoms of multiple sclerosis, including spasticity and neuropathic pain. THC acts as a partial
Tetrahydrocannabinol
British sprinter (born 1996)
In August 2022, Nielsen disclosed that she had been diagnosed with multiple sclerosis in the summer of 2021. Her twin sister Lina had been diagnosed with
Laviai_Nielsen
Integrin dimer
knocked out in mice, it resulted in an embryonic lethal mutation. In multiple sclerosis (MS), the VLA-4 integrin is essential in the processes by which T-cells
VLA-4
Immune response against an organism's own healthy cells
arthritis, ankylosing spondylitis, polymyositis, dermatomyositis, and multiple sclerosis. Autoimmune diseases are very often treated with steroids. Autoimmunity
Autoimmunity
American actress (1935–2003)
Rides Tall. They divorced in 1970. In 1977, Rhue was diagnosed with multiple sclerosis. She continued to work, including a role in Days of Our Lives, but
Madlyn_Rhue
German immunologist, biomedical researcher
implications toward understanding Neurodegeneration and tissue loss in Multiple Sclerosis, Alzheimer disease and brain cancer. He has received recognition for
Burkhard_Becher
American physician (born 1949)
discoveries on the genetic basis, immune mechanisms, and treatment of multiple sclerosis (MS), most notably the development of B cell therapies for MS patients
Stephen_L._Hauser
Organic compound
multiple sclerosis were significantly lower compared to those of healthy controls, possibly indicating a diagnostic biomarker for multiple sclerosis.
Uric_acid
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
Boy/Male
Australian, Vietnamese
Many; Multiple
Boy/Male
Muslim
Multiple lights. Luster.
Boy/Male
Hebrew
God will multiply.
Girl/Female
Hebrew
God will multiply.
Girl/Female
Hebrew
God will multiply.
Boy/Male
Hebrew Spanish
God will multiply.
Boy/Male
Hebrew
God will multiply.
Boy/Male
Dutch, German, Hebrew
God will Multiply
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hebrew
God shall multiply.
Girl/Female
Hebrew
God will multiply.
Boy/Male
Hebrew Gaelic
God will multiply.
Boy/Male
Hebrew Spanish
God will multiply.
Boy/Male
Hindu, Indian
Un Countable; Multiple; Countless
Girl/Female
Hebrew
God will multiply.
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hebrew American Latin
God will multiply.
Boy/Male
Hindu, Indian, Tamil
Multiple
Boy/Male
Hebrew
God will multiply.
Boy/Male
Hebrew
God will multiply.
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
Boy/Male
Tamil
Lord Vishnu
Male
Dutch
, warrior of judgment.
Boy/Male
Bengali, Hindu, Indian
Good Mind
Girl/Female
Hindu, Indian, Punjabi, Sikh
Steady; Mountainous
Boy/Male
Hindu
Quite nature
Girl/Female
Latin
Royal grace.
Girl/Female
Tamil
Goddess name
Girl/Female
Indian
Whom's Luck is Fortunate
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Lion of the Battlefield
Girl/Female
German
Bright
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
MULTIPLE SCLEROSIS
v. t.
To redouble; to multiply; to repeat.
p. pr. & vb. n.
of Multiply
n.
The multiplier.
a.
Containing more than once, or more than one; consisting of more than one; manifold; repeated many times; having several, or many, parts.
n.
Multiplied diversity.
n.
The number by which another number is multiplied. See the Note under Multiplication.
n.
A quantity containing another quantity a number of times without a remainder.
n.
One who, or that which, multiplies or increases number.
v. i.
To increase in extent and influence; to spread.
v. t.
To add (any given number or quantity) to itself a certain number of times; to find the product of by multiplication; thus 7 multiplied by 8 produces the number 56; to multiply two numbers. See the Note under Multiplication.
v. t.
To multiply; to make manifold.
a.
Having many flues; as, a multiflue boiler. See Boiler.
a.
Tending to multiply; having the power to multiply, or incease numbers.
n.
The number which is to be multiplied by another number called the multiplier. See Note under Multiplication.
n.
The number by which another number is multiplied; a multiplier.
a.
Manifold; multiple.
imp. & p. p.
of Multiply
adv.
So as to multiply.
v. i.
To increase amount of gold or silver by the arts of alchemy.
v. t.
To multiply; to increase.